Kühnle, Ingrid

[["dc.bibliographiccitation.firstpage","851"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Blood"],["dc.bibliographiccitation.lastpage","860"],["dc.bibliographiccitation.volume","124"],["dc.contributor.author","Rensing-Ehl, Anne"],["dc.contributor.author","Voelkl, Simon"],["dc.contributor.author","Speckmann, Carsten"],["dc.contributor.author","Lorenz, Myriam Ricarda"],["dc.contributor.author","Ritter, Julia"],["dc.contributor.author","Janda, Ales"],["dc.contributor.author","Abinun, Mario"],["dc.contributor.author","Pircher, Hanspeter"],["dc.contributor.author","Bengsch, Bertram"],["dc.contributor.author","Thimme, Robert"],["dc.contributor.author","Fuchs, Ilka"],["dc.contributor.author","Ammann, Sandra"],["dc.contributor.author","Allgaeuer, Andrea"],["dc.contributor.author","Kentouche, Karim"],["dc.contributor.author","Cant, Andrew"],["dc.contributor.author","Hambleton, Sophie"],["dc.contributor.author","da Cunha, Claudia Bettoni"],["dc.contributor.author","Huetker, Sebastian"],["dc.contributor.author","Kuehnle, Ingrid"],["dc.contributor.author","Pekrun, Arnulf"],["dc.contributor.author","Seidel, Markus G."],["dc.contributor.author","Hummel, Michael"],["dc.contributor.author","Mackensen, Andreas"],["dc.contributor.author","Schwarz, Klaus"],["dc.contributor.author","Ehl, Stephan"],["dc.date.accessioned","2018-11-07T09:36:42Z"],["dc.date.available","2018-11-07T09:36:42Z"],["dc.date.issued","2014"],["dc.description.abstract","Accumulation of CD3(+) T-cell receptor (TCR)alpha beta(+)CD4(-)CD8(-) double-negative T cells(DNT) is a hallmark of autoimmune lymphoproliferative syndrome (ALPS). DNT origin and differentiation pathways remain controversial. Here we show that human ALPS DNT have features of terminally differentiated effector memory T cells reexpressing CD45RA(+) (TEMRA), but are CD27(+)CD28(+)KLRG1(-) and do not express the transcription factor T-bet. This unique phenotype was also detected among CD4(+) or CD8(+) ALPS TEMRA cells. T-cell receptor beta deep sequencing revealed a significant fraction of shared CDR3 sequences between ALPS DNT and both CD4(+) and CD8(+) TEMRA cells. Moreover, in ALPS patients with a germ line FAS mutation and somatic loss of heterozygosity, in whom biallelic mutant cells can be tracked by absent Fas expression, Fas-negative T cells accumulated not only among DNT, but also among CD4(+) and CD8(+)TEMRA cells. These data indicate that in human Fas deficiency DNT cannot only derive from CD8(+), but also from CD4(+) T cells. Furthermore, defective Fas signaling leads to aberrant transcriptional programs and differentiation of subsets of CD4(+) and CD8(+) T cells. Accumulation of these cells before their double-negative state appears to be an important early event in the pathogenesis of lymphoproliferation in ALPS patients."],["dc.identifier.doi","10.1182/blood-2014-03-564286"],["dc.identifier.isi","000342620400012"],["dc.identifier.pmid","24894771"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32677"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Soc Hematology"],["dc.relation.issn","1528-0020"],["dc.relation.issn","0006-4971"],["dc.title","Abnormally differentiated CD4(+) or CD8(+) T cells with phenotypic and genetic features of double negative T cells in human Fas deficiency"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","984"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","994"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Hartmann, Franziska"],["dc.contributor.author","Lockmann, Anike"],["dc.contributor.author","Himpel, Okko"],["dc.contributor.author","Kühnle, Ingrid"],["dc.contributor.author","Hensen, Janina"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Thoms, Kai‐Martin"],["dc.date.accessioned","2021-04-14T08:22:56Z"],["dc.date.available","2021-04-14T08:22:56Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1111/ddg.14184_g"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80738"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Orale Propranolol‐ und Neodym:YAG‐Farbstofflaser‐Kombinationstherapie infantiler Hämangiome: eine retrospektive Analyse von 30 Kindern mit 48 Hämangiomen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Lockmann, Anike"],["dc.contributor.author","Groenemeyer, L.-L."],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Zutt, Markus"],["dc.contributor.author","von Fintel, H."],["dc.contributor.author","Kuehnle, Ingrid"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Thoms, Kai Martin"],["dc.date.accessioned","2018-11-07T09:58:42Z"],["dc.date.available","2018-11-07T09:58:42Z"],["dc.date.issued","2015"],["dc.format.extent","97"],["dc.identifier.isi","000360219000277"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37426"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Nd:YAG- and pulsed Colouring Laster-Therapy of 271 infantile Haemangiomas in 149 Children: a retrospective Analysis"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e27012"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Pediatric Blood & Cancer"],["dc.bibliographiccitation.volume","65"],["dc.contributor.author","Kube, Stefanie"],["dc.contributor.author","Vokuhl, Christian"],["dc.contributor.author","Dantonello, Tobias"],["dc.contributor.author","Scheer, Monika"],["dc.contributor.author","Hallmen, Erika"],["dc.contributor.author","Feuchtgruber, Simone"],["dc.contributor.author","Escherich, Gabriele"],["dc.contributor.author","Niggli, Felix"],["dc.contributor.author","Kuehnle, Ingrid"],["dc.contributor.author","von Kalle, Thekla"],["dc.contributor.author","Bielack, Stefan"],["dc.contributor.author","Klingebiel, Thomas"],["dc.contributor.author","Koscielniak, Ewa"],["dc.date.accessioned","2020-12-10T14:07:03Z"],["dc.date.available","2020-12-10T14:07:03Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1002/pbc.v65.6"],["dc.identifier.issn","1545-5009"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70112"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Inflammatory myofibroblastic tumors-A retrospective analysis of the Cooperative Weichteilsarkom Studiengruppe"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3555"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Cancers"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Hell, Anna K."],["dc.contributor.author","Kühnle, Ingrid"],["dc.contributor.author","Lorenz, Heiko M."],["dc.contributor.author","Braunschweig, Lena"],["dc.contributor.author","Lüders, Katja A."],["dc.contributor.author","Bock, Hans Christoph"],["dc.contributor.author","Kramm, Christof M."],["dc.contributor.author","Ludwig, Hans Christoph"],["dc.contributor.author","Tsaknakis, Konstantinos"],["dc.date.accessioned","2021-04-14T08:27:47Z"],["dc.date.available","2021-04-14T08:27:47Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.3390/cancers12123555"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82404"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.publisher","MDPI"],["dc.relation.eissn","2072-6694"],["dc.rights","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Spinal Deformities after Childhood Tumors"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Journal of Clinical Immunology"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Rensing-Ehl, Anne"],["dc.contributor.author","Voelkl, Simon"],["dc.contributor.author","Speckmann, Carsten"],["dc.contributor.author","Lorenz, Myriam Ricarda"],["dc.contributor.author","Ritter, J."],["dc.contributor.author","Janda, Ales"],["dc.contributor.author","Abinun, Mario"],["dc.contributor.author","Pircher, Hanspeter"],["dc.contributor.author","Bengsch, B."],["dc.contributor.author","Thimme, Robert"],["dc.contributor.author","Fuchs, Ilka"],["dc.contributor.author","Ammann, Sandra"],["dc.contributor.author","Allgaeuer, Andrea"],["dc.contributor.author","Kentouche, Karim"],["dc.contributor.author","Cant, A."],["dc.contributor.author","Hambleton, Sophie"],["dc.contributor.author","da Cunha, Claudia Bettoni"],["dc.contributor.author","Huetker, Sebastian"],["dc.contributor.author","Kuehnle, Ingrid"],["dc.contributor.author","Pekrun, Arnulf"],["dc.contributor.author","Seidel, Markus G."],["dc.contributor.author","Hummel, Michael"],["dc.contributor.author","Mackensen, Andreas"],["dc.contributor.author","Schwarz, K."],["dc.contributor.author","Ehl, Stephan"],["dc.date.accessioned","2018-11-07T09:33:54Z"],["dc.date.available","2018-11-07T09:33:54Z"],["dc.date.issued","2014"],["dc.format.extent","S165"],["dc.identifier.isi","000347389100046"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32064"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.conference","16th Biennial Meeting of the European-Society-for-Immunodeficiencies"],["dc.relation.eventlocation","Prague, CZECH REPUBLIC"],["dc.relation.issn","1573-2592"],["dc.relation.issn","0271-9142"],["dc.title","Abnormally Differentiated CD4+OR CD8+T-Cells with Phenotypic and Genetic Features of Double Negative T-Cells in Human FAS Deficiency"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Neuro-Oncology"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Friedrich, Carsten"],["dc.contributor.author","Kuehn, Alexander"],["dc.contributor.author","Zimmermann, Martin"],["dc.contributor.author","Hoffmann, Marion"],["dc.contributor.author","Kuehnle, Ingrid"],["dc.contributor.author","Nowak, Johannes"],["dc.contributor.author","Warmuth-Metz, Monika"],["dc.contributor.author","Pietsch, Torsten"],["dc.contributor.author","Schrappe, Martin"],["dc.contributor.author","Escherich, Gabriele"],["dc.contributor.author","Burkhardt, Birgit"],["dc.contributor.author","Kortmann, Rolf-Dieter"],["dc.contributor.author","von Bueren, Andre Oscar"],["dc.contributor.author","Kramm, Christof M."],["dc.date.accessioned","2018-11-07T10:13:06Z"],["dc.date.available","2018-11-07T10:13:06Z"],["dc.date.issued","2016"],["dc.format.extent","55"],["dc.identifier.isi","000379749000210"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40369"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.publisher.place","Cary"],["dc.relation.conference","17th International Symposium on Pediatric Neuro-Oncology (ISPNO)"],["dc.relation.eventlocation","Liverpool, ENGLAND"],["dc.relation.issn","1523-5866"],["dc.relation.issn","1522-8517"],["dc.title","HIGH-GRADE GLIOMA ARISING IN SURVIVORS OF PEDIATRIC ACUTE LYMPHOBLASTIC MALIGNANCIES: A COOPERATIVE ANALYSIS OF THE GERMAN HIT-HGG/-GBM AND ALL-BFM/COALL STUDIES"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Pediatric Blood & Cancer"],["dc.bibliographiccitation.volume","63"],["dc.contributor.author","Scheer, M."],["dc.contributor.author","Hallmen, E."],["dc.contributor.author","Sparber-Sauer, M."],["dc.contributor.author","Vokuhl, C."],["dc.contributor.author","Leuschner, Ivo"],["dc.contributor.author","Hartwig, M."],["dc.contributor.author","Kuhnle, Ingrid"],["dc.contributor.author","Seitz, G."],["dc.contributor.author","Ladenstein, Ruth"],["dc.contributor.author","Niggli, F."],["dc.contributor.author","Gustaf, L."],["dc.contributor.author","Bielack, Stefan S."],["dc.contributor.author","Thomas, Kelly A."],["dc.contributor.author","Koscielniak, Ewa"],["dc.date.accessioned","2018-11-07T10:06:11Z"],["dc.date.available","2018-11-07T10:06:11Z"],["dc.date.issued","2016"],["dc.format.extent","S262"],["dc.identifier.isi","000384818801548"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39040"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1545-5017"],["dc.relation.issn","1545-5009"],["dc.title","Desmoplastic Small Round Cell Tumors (DSRCT) in Children and Adolescents Experience of the CWS Study Group"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","73"],["dc.bibliographiccitation.journal","Journal of Clinical Immunology"],["dc.bibliographiccitation.lastpage","74"],["dc.bibliographiccitation.volume","32"],["dc.contributor.author","Rensing-Ehl, Anne"],["dc.contributor.author","Janda, Ales"],["dc.contributor.author","Vach, Werner"],["dc.contributor.author","Gladstone, Beryl P."],["dc.contributor.author","Abinun, Mario"],["dc.contributor.author","Albert, M. H."],["dc.contributor.author","Butler, Karina"],["dc.contributor.author","Cant, A."],["dc.contributor.author","Cseh, Anna-Maria"],["dc.contributor.author","Ebinger, Martin"],["dc.contributor.author","Goldacker, Sigune"],["dc.contributor.author","Hambleton, Sophie"],["dc.contributor.author","Hebart, Holger F."],["dc.contributor.author","Houet, Leonora"],["dc.contributor.author","Kentouche, Karim"],["dc.contributor.author","Kuehnle, Ingrid"],["dc.contributor.author","Lehmberg, Kai"],["dc.contributor.author","Mejstrikova, Ester"],["dc.contributor.author","Niemeyer, C."],["dc.contributor.author","Minkov, Milen"],["dc.contributor.author","Neth, O."],["dc.contributor.author","Dueckers, Gregor"],["dc.contributor.author","Owens, S."],["dc.contributor.author","Richards, M."],["dc.contributor.author","Roesler, J."],["dc.contributor.author","Schilling, Freimut H."],["dc.contributor.author","Schuster, Volker"],["dc.contributor.author","Seidel, Markus G."],["dc.contributor.author","Smisek, Petr"],["dc.contributor.author","Sukova, Martina"],["dc.contributor.author","Svec, Peter"],["dc.contributor.author","Wiesel, Thomas"],["dc.contributor.author","Lorenz, M."],["dc.contributor.author","Schwarz, K."],["dc.contributor.author","Ehl, Stephan"],["dc.contributor.author","Speckmann, Carsten"],["dc.date.accessioned","2018-11-07T09:06:30Z"],["dc.date.available","2018-11-07T09:06:30Z"],["dc.date.issued","2012"],["dc.identifier.isi","000308728900140"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25578"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.conference","15th Biennial Meeting European-Society-for-Immunodeficiency (ESID)"],["dc.relation.eventlocation","Florence, ITALY"],["dc.relation.issn","0271-9142"],["dc.title","WHEN SHOULD THE FAS GENE BE SEQUENCED IN PATIENTS WITH LYMPHOPROLIFERATION AND AUTOIMMUNITY"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","56"],["dc.bibliographiccitation.journal","Diagnostic Pathology"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Schildhaus, Hans-Ulrich"],["dc.contributor.author","Lokka, Suvi"],["dc.contributor.author","Fenner, Werner"],["dc.contributor.author","Kuester, Jens"],["dc.contributor.author","Kuehnle, Ingrid"],["dc.contributor.author","Heinmoeller, Ernst"],["dc.date.accessioned","2018-11-07T10:12:34Z"],["dc.date.available","2018-11-07T10:12:34Z"],["dc.date.issued","2016"],["dc.description.abstract","Background: Embryonal rhabdomyosarcoma of the prostate in an adult is a very rare event with only a few cases published. Diagnosis usually occurs with advanced disease frequently already with metastatic spread. In adults prognosis is very poor, therefore early diagnosis is crucial. To date, only three cases of spindle cell subtype of embryonal rhabdomyosarcoma of the prostate in an adult have been published. Case presentation: We report an additional case of prostatic spindle cell embryonal rhabdomyosarcoma subtype in an adult. Conclusions: We discuss relevant clinicopathological features of spindle cell embryonal rhabdomyosarcoma of the prostate in adult patients in the context of the literature."],["dc.identifier.doi","10.1186/s13000-016-0507-1"],["dc.identifier.isi","000379299000001"],["dc.identifier.pmid","27357857"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/13382"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40263"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","1746-1596"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Spindle cell embryonal rhabdomyosarcoma of the prostate in an adult patient - case report and review of clinicopathological features"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]