Now showing 1 - 10 of 31
  • 2021Journal Article
    [["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","01"],["dc.bibliographiccitation.journal","Trace Elements and Electrolytes"],["dc.bibliographiccitation.lastpage","7"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Büntzel, Judith"],["dc.contributor.author","Bauer, Christoph"],["dc.contributor.author","Kisters, Klaus"],["dc.contributor.author","Büntzel, Jens"],["dc.date.accessioned","2021-04-14T08:29:34Z"],["dc.date.available","2021-04-14T08:29:34Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.5414/TEX01654"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82935"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.issn","0946-2104"],["dc.title","Make experience visible: Possible new data management in phytotherapy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.artnumber","e16712"],["dc.bibliographiccitation.issue","31"],["dc.bibliographiccitation.journal","Medicine"],["dc.bibliographiccitation.volume","98"],["dc.contributor.author","Buentzel, Judith"],["dc.contributor.author","Yao, Sha"],["dc.contributor.author","Elakad, Omar"],["dc.contributor.author","Lois, Anna-Maria"],["dc.contributor.author","Brünies, Jana"],["dc.contributor.author","König, Julia"],["dc.contributor.author","Hinterthaner, Marc"],["dc.contributor.author","Danner, Bernhard C."],["dc.contributor.author","Ströbel, Philipp"],["dc.contributor.author","Emmert, Alexander"],["dc.contributor.author","Bohnenberger, Hanibal"],["dc.date.accessioned","2019-08-09T06:40:34Z"],["dc.date.available","2019-08-09T06:40:34Z"],["dc.date.issued","2019"],["dc.description.abstract","Molecular characterization of lung cancer specimens after radical surgery offers additional prognostic information and may help to guide adjuvant therapeutic procedures. The transcriptional regulators alpha thalassemia/mental retardation X-linked (ATRX) and death domain-associated protein (DAXX) have recently been described in different cancer entities as a useful prognostic biomarker. This study was initiated to explore their protein expression patterns and prognostic value in patients with operable lung cancer disease.The protein abundance (in the following text also named protein expression) of ATRX and DAXX were analyzed by immunohistochemistry in 194 samples of squamous cell lung carcinoma (SQCLC), 111 samples of pulmonary adenocarcinoma (AC) and 40 samples of small cell lung cancer (SCLC). The protein levels of ATRX and DAXX were correlated with clinicopathological characteristics and patient outcome.ATRX showed strong protein expression in 16.2% of AC, 11.9% of SQCLC, and 42.5% of SCLC. DAXX was highly expressed in 54.9% of AC, 76.2% of SQCLC, and 82.5% of SCLC. Immunostaining of both ATRX and DAXX were seen in 14.4% of AC, 11.3% of SQCLC, and 42.5% of SCLC. High protein expression of ATRX was a favorable prognostic marker for patients with AC (hazard ratio 0.38, P = .02). Sub-group analyses showed a significant correlation between ATRX and the clinical stage of SQCLC and SCLC. Histological grading and ATRX were also significantly associated in cases of SQCLC.The presence of ATRX and DAXX are correlated with lung cancer histology. Strong ATRX protein expression is associated with a significantly longer overall survival in patients with AC."],["dc.description.sponsorship","Open-Access-Publikationafonds 2019"],["dc.identifier.doi","10.1097/MD.0000000000016712"],["dc.identifier.pmid","31374064"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16343"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62353"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","1536-5964"],["dc.relation.issn","0025-7974"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.title","Expression and prognostic impact of alpha thalassemia/mental retardation X-linked and death domain-associated protein in human lung cancer"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2020Journal Article
    [["dc.bibliographiccitation.firstpage","283"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Der Onkologe"],["dc.bibliographiccitation.lastpage","288"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Büntzel, Judith"],["dc.contributor.author","Mathies, Viktoria"],["dc.contributor.author","Hübner, Jutta"],["dc.contributor.author","Büntzel, Jens"],["dc.date.accessioned","2021-04-14T08:27:13Z"],["dc.date.available","2021-04-14T08:27:13Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s00761-020-00717-6"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82210"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1433-0415"],["dc.relation.issn","0947-8965"],["dc.title","Komplementärmedizinische Behandlungsansätze bei Gastritis und funktionellen Magenbeschwerden während der Tumortherapie"],["dc.title.translated","Complementary treatment approaches for patients with gastritis and functional dyspepsia during anticancer treatment"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2021Journal Article
    [["dc.bibliographiccitation.firstpage","3213"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Anticancer Research"],["dc.bibliographiccitation.lastpage","3232"],["dc.bibliographiccitation.volume","41"],["dc.contributor.author","GREMMLER, LENNART"],["dc.contributor.author","KUTSCHAN, SABINE"],["dc.contributor.author","DÖRFLER, JENNIFER"],["dc.contributor.author","BÜNTZEL, JUDITH"],["dc.contributor.author","BÜNTZEL, JENS"],["dc.contributor.author","HÜBNER, JUTTA"],["dc.date.accessioned","2021-09-01T06:38:21Z"],["dc.date.available","2021-09-01T06:38:21Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.21873/anticanres.15108"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88914"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-455"],["dc.relation.eissn","1791-7530"],["dc.relation.issn","0250-7005"],["dc.title","Proteolytic Enzyme Therapy in Complementary Oncology: A Systematic Review"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article
    [["dc.bibliographiccitation.journal","Journal of Cancer Research and Clinical Oncology"],["dc.contributor.author","Ritschel, Maria-Louisa"],["dc.contributor.author","Hübner, Jutta"],["dc.contributor.author","Wurm-Kuczera, Rebecca"],["dc.contributor.author","Büntzel, Judith"],["dc.date.accessioned","2022-09-01T09:49:17Z"],["dc.date.available","2022-09-01T09:49:17Z"],["dc.date.issued","2022"],["dc.description.abstract","Abstract\n \n Background\n Plant remedies are often used next to conventional standard of care by cancer patients. However, user rates are often underestimated and physicians usually feel not equipped to counsel patients. Hence, routinely recording the use of phytotherapy and sufficient knowledge on herbal medicine of the medical staff are required to improve the situation. Appraising the current state of knowledge of medical students may offer insight if education on herbals needs improvement. Here, we propose a simple anamnesis tool to assess knowledge and usage pattern of medical plants and demonstrate how to extrapolate symptom cluster participants associated with plants investigated in this study focussing on the common symptom of oral discomfort.\n \n \n Methods\n By screening German literature (popular science, specialist’s literature, books for the interested layman) on medical plants used for treating oral discomfort, we were able to deviate a list of plants most often recommended for treating oral discomfort and to develop an anamnesis tool to assess knowledge and usage of 16 different plants. A group of 120 head-neck cancer patients (under surveillance, after receiving treatment) and 168 medical students were questioned at a collaborating out-patient clinic and via an online survey, respectively, in 2020. Students were additionally asked to write down indications of the plants they used in daily life. Knowledge and usage pattern were compared between both groups. Primary component analysis and heat-map analysis were used to visualize common and distinguishing features. Network analysis and VENN diagrams were used to extrapolate data of the medical students’ cohort.\n \n \n Results\n \n Head-neck cancer patients and students show similar knowledge. However, students used significantly more plants in daily life than patients (\n p\n  < 0.001). Overall, the user rate of patients and students were 82.50 and 93.94%, respectively. The top five most commonly known plants were similar in both groups (\n Marticaria recutita L.\n ,\n Zingiber offinicale ROSCOE, Taraxacum Wigg. Calendula officinalis L.\n ) with the exception of\n Salvia officinalis L.\n (patients’ cohort) and\n Carum carvi/Cuminum cyminum L.\n (students’ cohort). Despite this slight difference, usage pattern of the top five most commonly used plants was the same between the groups. Students’ indications were compared to indications found in the literature, unmasking several differences between commonly practiced and written knowledge on German phytotherapy. Network analysis revealed, that students associated certain plants with corresponding symptom clusters (e.g., coughing, oral mucositis).\n \n \n \n Conclusion\n The majority of surveyed cancer patients as well as medical students use phytotherapy for treating oral discomfort. Both groups know and use similar plants. However, indications of written folk medicine differ from the lived and practiced tradition."],["dc.identifier.doi","10.1007/s00432-022-04200-0"],["dc.identifier.pii","4200"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113384"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.eissn","1432-1335"],["dc.relation.issn","0171-5216"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Phytotherapy known and applied by head-neck cancer patients and medical students to treat oral discomfort in Germany: an observational study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","269"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Der Onkologe"],["dc.bibliographiccitation.lastpage","274"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Büntzel, Judith"],["dc.contributor.author","Hübner, Jutta"],["dc.contributor.author","Büntzel, Jens"],["dc.date.accessioned","2020-12-10T14:11:00Z"],["dc.date.available","2020-12-10T14:11:00Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1007/s00761-019-0521-5"],["dc.identifier.eissn","1433-0415"],["dc.identifier.issn","0947-8965"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70936"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Komplementärmedizinische Behandlungsansätze bei oraler Mukositis und Xerostomie"],["dc.title.alternative","Complementary medical treatment approaches for oral mucositis and xerostomia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","615"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Der Onkologe"],["dc.bibliographiccitation.lastpage","620"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Büntzel, Judith"],["dc.contributor.author","Hübner, Jutta"],["dc.contributor.author","Steinau, Philipp"],["dc.contributor.author","Büntzel, Jens"],["dc.date.accessioned","2020-12-10T14:11:00Z"],["dc.date.available","2020-12-10T14:11:00Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1007/s00761-019-0590-5"],["dc.identifier.eissn","1433-0415"],["dc.identifier.issn","0947-8965"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70937"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Komplementärmedizinische Behandlungsansätze bei Verlust des Riechens und Schmeckens"],["dc.title.alternative","Complementary medical treatment approaches for patients with loss of smell and taste"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","979"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","In Vivo"],["dc.bibliographiccitation.lastpage","982"],["dc.bibliographiccitation.volume","33"],["dc.contributor.author","BÜNTZEL, JUDITH"],["dc.contributor.author","MICKE, OLIVER"],["dc.contributor.author","KISTERS, KLAUS"],["dc.contributor.author","BÜNTZEL, JENS"],["dc.contributor.author","MÜCKE, RALPH"],["dc.date.accessioned","2020-12-10T18:43:04Z"],["dc.date.available","2020-12-10T18:43:04Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.21873/invivo.11567"],["dc.identifier.eissn","1791-7549"],["dc.identifier.issn","0258-851X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78184"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Malnutrition and Survival – Bioimpedance Data in Head Neck Cancer Patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","4603"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Anticancer Research"],["dc.bibliographiccitation.lastpage","4612"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","BUENTZEL, JUDITH"],["dc.contributor.author","HEINZ, JUDITH"],["dc.contributor.author","BLECKMANN, ANNALEN"],["dc.contributor.author","BAUER, CHRISTOPH"],["dc.contributor.author","RÖVER, CHRISTIAN"],["dc.contributor.author","BOHNENBERGER, HANIBAL"],["dc.contributor.author","SAHA, SHEKHAR"],["dc.contributor.author","HINTERTHANER, MARC"],["dc.contributor.author","BARAKI, HASSINA"],["dc.contributor.author","KUTSCHKA, INGO"],["dc.contributor.author","EMMERT, ALEXANDER"],["dc.date.accessioned","2020-12-10T18:43:04Z"],["dc.date.available","2020-12-10T18:43:04Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.21873/anticanres.13640"],["dc.identifier.eissn","1791-7530"],["dc.identifier.issn","0250-7005"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78183"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Sarcopenia as Prognostic Factor in Lung Cancer Patients: A Systematic Review and Meta-analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","e1847"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","The International Journal of Medical Robotics and Computer Assisted Surgery"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Buentzel, Judith"],["dc.contributor.author","Heinz, Judith"],["dc.contributor.author","Hinterthaner, Marc"],["dc.contributor.author","Schöndube, Friedrich A."],["dc.contributor.author","Straube, Carmen"],["dc.contributor.author","Roever, Christian"],["dc.contributor.author","Emmert, Alexander"],["dc.date.accessioned","2020-12-10T14:07:09Z"],["dc.date.available","2020-12-10T14:07:09Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1002/rcs.v13.4"],["dc.identifier.issn","1478-5951"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70138"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Robotic versus thoracoscopic thymectomy: The current evidence"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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