Holke, Karin

[["dc.bibliographiccitation.artnumber","46"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Intensive Care Medicine Experimental"],["dc.bibliographiccitation.volume","5"],["dc.contributor.author","Cambiaghi, Barbara"],["dc.contributor.author","Vasques, Francesco"],["dc.contributor.author","Mörer, Onnen"],["dc.contributor.author","Ritter, Christian"],["dc.contributor.author","Mauri, Tommaso"],["dc.contributor.author","Kunze-Szikszay, Nils"],["dc.contributor.author","Holke, Karin"],["dc.contributor.author","Collino, Francesca"],["dc.contributor.author","Maiolo, Giorgia"],["dc.contributor.author","Rapetti, Francesca"],["dc.contributor.author","Schulze-Kalthoff, Elias"],["dc.contributor.author","Tonetti, Tommaso"],["dc.contributor.author","Hahn, Günter"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Gattinoni, Luciano"],["dc.date.accessioned","2020-12-10T18:41:24Z"],["dc.date.available","2020-12-10T18:41:24Z"],["dc.date.issued","2017"],["dc.description.abstract","Abstract Background Severe hypoperfusion can cause lung damage. We studied the effects of regional perfusion block in normal lungs and in the lungs that had been conditioned by lavage with 500 ml saline and high V T (20 ml kg−1) ventilation. Methods Nineteen pigs (61.2 ± 2.5 kg) were randomized to five groups: controls (n = 3), the right lower lobe block alone (n = 3), lavage and high V T (n = 4), lung lavage, and high V T plus perfusion block of the right (n = 5) or left (n = 4) lower lobe. Gas exchange, respiratory mechanics, and hemodynamics were measured hourly. After an 8-h observation period, CT scans were obtained at 0 and 15 cmH2O airway pressure. Results Perfusion block did not damage healthy lungs. In conditioned lungs, the left perfusion block caused more edema in the contralateral lung (777 ± 62 g right lung vs 484 ± 204 g left; p < 0.05) than the right perfusion block did (581 ± 103 g right lung vs 484 ± 204 g left; p n.s.). The gas/tissue ratio, however, was similar (0.5 ± 0.3 and 0.8 ± 0.5; p n.s.). The lobes with perfusion block were not affected (gas/tissue ratio right 1.6 ± 0.9; left 1.7 ± 0.5, respectively). Pulmonary artery pressure, PaO2/FiO2, dead space, and lung mechanics were more markedly affected in animals with left perfusion block, while the gas/tissue ratios were similar in the non-occluded lobes. Conclusions The right and left perfusion blocks caused the same “intensity” of edema in conditioned lungs. The total amount of edema in the two lungs differed because of differences in lung size. If capillary permeability is altered, increased blood flow may induce or increase edema."],["dc.identifier.doi","10.1186/s40635-017-0161-2"],["dc.identifier.eissn","2197-425X"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15183"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77572"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.publisher","Springer"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Effects of regional perfusion block in healthy and injured lungs"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","869"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Der Internist"],["dc.bibliographiccitation.lastpage","+"],["dc.bibliographiccitation.volume","53"],["dc.contributor.author","Muehlhausen, Johannes"],["dc.contributor.author","Mueller, Georg Anton"],["dc.contributor.author","Eiffert, Helmut"],["dc.contributor.author","Wulf, Gerald"],["dc.contributor.author","Holke, Karin"],["dc.contributor.author","Koziolek, Michael Johann"],["dc.date.accessioned","2018-11-07T09:08:39Z"],["dc.date.available","2018-11-07T09:08:39Z"],["dc.date.issued","2012"],["dc.description.abstract","Sarcoidosis is a multi-systemic disease. A 21-year-old female patient was admitted to our department with lymphadenopathy, B symptoms, erythema nodosum and joint pain. Sarcoidosis showed a very atypical course, lacking any pulmonary symptoms or typical laboratory values. The diagnosis was finally confirmed histologically and thus various differential diagnoses such as microbiological and malignant diseases could be excluded. Oral steroid medication led to remission."],["dc.identifier.doi","10.1007/s00108-012-3049-y"],["dc.identifier.isi","000305803900008"],["dc.identifier.pmid","22484921"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26082"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0020-9554"],["dc.title","B symptoms, lymphadenopathy and signs of systemic disease in a 21-year-old female"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1175"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Der Ophthalmologe"],["dc.bibliographiccitation.lastpage","1177"],["dc.bibliographiccitation.volume","108"],["dc.contributor.author","Atili, A."],["dc.contributor.author","Holke, Karin"],["dc.contributor.author","Karimdadian, Desiree"],["dc.contributor.author","Schittkowski, Michael P."],["dc.date.accessioned","2018-11-07T08:49:26Z"],["dc.date.available","2018-11-07T08:49:26Z"],["dc.date.issued","2011"],["dc.description.abstract","A 22-year-old patient presented with persistent epiphora over a period of about 7 months. The clinical examination revealed a canalicular swelling in both lacrimal ducts, which postoperatively transpired to be an exophytic tumor. The histopathology result of the excised tumor showed an epithelial lesion, a partially inverted papilloma without malignancy. For tumors arising from lachrimal ducts the first-line therapy is complete tumor resection."],["dc.identifier.doi","10.1007/s00347-011-2437-3"],["dc.identifier.isi","000297709800014"],["dc.identifier.pmid","22016192"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21456"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0941-293X"],["dc.title","Recurrent canaliculitis in a 22-year-old patient"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","119"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Anesthesiology"],["dc.bibliographiccitation.lastpage","130"],["dc.bibliographiccitation.volume","130"],["dc.contributor.author","Collino, Francesca"],["dc.contributor.author","Rapetti, Francesca"],["dc.contributor.author","Vasques, Francesco"],["dc.contributor.author","Maiolo, Giorgia"],["dc.contributor.author","Tonetti, Tommaso"],["dc.contributor.author","Romitti, Federica"],["dc.contributor.author","Niewenhuys, Julia"],["dc.contributor.author","Behnemann, Tim"],["dc.contributor.author","Camporota, Luigi"],["dc.contributor.author","Hahn, Günter"],["dc.contributor.author","Reupke, Verena"],["dc.contributor.author","Holke, Karin"],["dc.contributor.author","Herrmann, Peter"],["dc.contributor.author","Duscio, Eleonora"],["dc.contributor.author","Cipulli, Francesco"],["dc.contributor.author","Moerer, Onnen"],["dc.contributor.author","Marini, John J."],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Gattinoni, Luciano"],["dc.date.accessioned","2020-12-10T18:19:47Z"],["dc.date.available","2020-12-10T18:19:47Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1097/ALN.0000000000002458"],["dc.identifier.issn","0003-3022"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75382"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Positive End-expiratory Pressure and Mechanical Power"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","155"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.lastpage","157"],["dc.bibliographiccitation.volume","102"],["dc.contributor.author","Schroeter, M. R."],["dc.contributor.author","Unsoeld, Bernhard W."],["dc.contributor.author","Holke, Karin"],["dc.contributor.author","Schillinger, Wolfgang"],["dc.date.accessioned","2018-11-07T09:28:45Z"],["dc.date.available","2018-11-07T09:28:45Z"],["dc.date.issued","2013"],["dc.identifier.doi","10.1007/s00392-012-0494-5"],["dc.identifier.isi","000314036900008"],["dc.identifier.pmid","22829017"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8806"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30853"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1861-0684"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Pro-thrombotic condition in a woman with peripartum cardiomyopathy treated with bromocriptine and an Impella LP 2.5 heart pump"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]