Bertsch, Hans P.

[["dc.bibliographiccitation.firstpage","691"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Der Hautarzt"],["dc.bibliographiccitation.lastpage","695"],["dc.bibliographiccitation.volume","62"],["dc.contributor.author","Meyersburg, Damian"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Bertsch, Hans-Peter"],["dc.contributor.author","Seitz, Cornelia S."],["dc.date.accessioned","2018-11-07T08:52:36Z"],["dc.date.available","2018-11-07T08:52:36Z"],["dc.date.issued","2011"],["dc.description.abstract","Sarcoidosis is a granulomatous multisystemic disease of unclear etiology, which can affect any organ. The cutaneous manifestations are variable, but ulcerative cutaneous sarcoidosis is very yare. One must rule out other granulomatous skin diseases, especially necrobiosis lipoidica. There is no standarized therapy; usually an interdisciplinary acropachy over years taking multiple side effects into consideration is needed. A 58-year-old woman with a long history of cutaneous, nodal and pulmonary sarcoidosis suddenly developed ulcerations within the disseminated skin lesions on her legs. The combination of systemic hydroxychloroquine and modern wound management lead to complete healing of the ulcers and a significant improvement in the remaining skin lesions."],["dc.identifier.doi","10.1007/s00105-010-2120-7"],["dc.identifier.isi","000294498600012"],["dc.identifier.pmid","21656110"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22208"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0017-8470"],["dc.title","Uncommon cutaneous ulcerative and systemic sarcoidosis. Successful treatment with hydroxychloroquine and compression therapy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1495"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Investigative Dermatology"],["dc.bibliographiccitation.lastpage","1502"],["dc.bibliographiccitation.volume","122"],["dc.contributor.author","Hallermann, Christian"],["dc.contributor.author","Kaune, Kjell Matthias"],["dc.contributor.author","Siebert, Reiner"],["dc.contributor.author","Vermeer, M. H."],["dc.contributor.author","Tensen, C. P."],["dc.contributor.author","Willemze, R."],["dc.contributor.author","Gunawan, Bastian"],["dc.contributor.author","Bertsch, Hans-Peter"],["dc.contributor.author","Neumann, C."],["dc.date.accessioned","2018-11-07T10:48:33Z"],["dc.date.available","2018-11-07T10:48:33Z"],["dc.date.issued","2004"],["dc.description.abstract","The diagnostic and prognostic importance of recurrent chromosomal aberrations in systemic B cell lymphoma is well documented. In contrast, limited data exist on genetic changes in primary cutaneous B cell lymphoma. In this study we investigated chromosomal aberration patterns in two types of primary cutaneous B cell lymphoma with a different clinical behavior. Twenty-two primary cutaneous B cell lymphomas, including nine follicle center cell lymphomas and 13 large B cell lymphomas of the leg, were analyzed by comparative genomic hybridization and in part by fluorescence in situ hybridization. The most frequent imbalances detectable were gains in 18q (eight of 22), 1q (six of 22), 7 (six of 22), 12q (six of 22), or Xp (four of 22), and losses in 6q (four of 22). In contrast to large B cell lymphomas of the leg, primary cutaneous follicle center cell lymphomas had fewer imbalances and lacked translocations affecting the IGH locus. Gains in 18q (eight of 13) and losses in 6q (four of 13) as well as breakpoints within the IGH locus (six of 11) were restricted to the large B cell lymphomas of the leg subtype. Translocation t(14; 18) was excluded in 16 primary cutaneous B cell lymphomas of both subtypes that were studied by fluorescence in situ hybridization. These results suggest that primary cutaneous follicle center cell lymphoma and large B cell lymphoma of the leg are characterized by different chromosomal aberration patterns, which in part might determine the different clinical course of these malignancies."],["dc.identifier.doi","10.1111/j.0022-202X.2003.12635.x"],["dc.identifier.isi","000221693500024"],["dc.identifier.pmid","15175042"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/48225"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing Inc"],["dc.relation.issn","0022-202X"],["dc.title","Chromosomal aberration patterns differ in subtypes of primary cutaneous B cell lymphomas"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Kraus, Sophie Luise"],["dc.contributor.author","Mempel, Martin"],["dc.contributor.author","Bertsch, Hans-Peter"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Thoms, Kai Martin"],["dc.date.accessioned","2018-11-07T09:05:25Z"],["dc.date.available","2018-11-07T09:05:25Z"],["dc.date.issued","2012"],["dc.format.extent","E2"],["dc.identifier.doi","10.1111/j.1610-0387.2012.08012_suppl.x"],["dc.identifier.isi","000309186700005"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25308"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0379"],["dc.title","Successful treatment of severe cutaneous leishmaniasis with sodium Stibugluconat perilesional injections"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","37"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","45"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Hoffmann, Saskia"],["dc.contributor.author","Buhl, Timo"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Bertsch, Hans Peter"],["dc.contributor.author","Rosenberger, Albert"],["dc.date.accessioned","2018-11-07T10:04:00Z"],["dc.date.available","2018-11-07T10:04:00Z"],["dc.date.issued","2015"],["dc.description.abstract","BackgroundCertain melanoma histotypes carry a worse prognosis than others. We aimed to identify patient related factors associated with specific melanoma histotypes. Patients and methodsSingle center study including 347 melanoma patients, prospectively assessed for 22 variables leading to a database of more than 7600 features. ResultsMelanomas were histologically categorized as superficial spreading (SSM, 70.6%), nodular (NM; 12.7%), acrolentiginous (ALM; 4.0%), lentigo maligna (LMM; 3.8%), or unclassified melanoma (UCM; 8.9%). Well recognized melanoma risk indicators (i.e. many atypical nevi, freckles, previous melanoma), were significantly associated with SSM and LMM histotypes. NM and ALM patients carried significantly less common and/or atypical nevi. NM were mostly self-detected or detected by relatives. In contrast, SSM, LMM, and ALM were most frequently detected by dermatologists. NM and UCM were preferentially located on poorly observable sites, SSM on the lower limbs, ALM on plantar sites, and LMM on the head and neck. ALM and LMM patients were significantly older than other patients. A multinomial logistic model was designed to predict a certain melanoma histotype (overall accuracy 81%), which could be helpful to focus the attention of clinicians or may be integrated into fully automated diagnostic algorithms. ConclusionsMelanoma histotypes show significant differences regarding patients' characteristics."],["dc.identifier.doi","10.1111/ddg.12561"],["dc.identifier.isi","000347445900006"],["dc.identifier.pmid","25640492"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38598"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Assessment of melanoma histotypes and associated patient related factors: Basis for a predictive statistical model"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","317"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","EUROPEAN JOURNAL OF DERMATOLOGY"],["dc.bibliographiccitation.lastpage","322"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Hallermann, Christian"],["dc.contributor.author","Middel, Peter"],["dc.contributor.author","Griesinger, Frank"],["dc.contributor.author","Gunawan, Bastian"],["dc.contributor.author","Bertsch, Hans-Peter"],["dc.contributor.author","Neumann, C."],["dc.date.accessioned","2018-11-07T10:45:55Z"],["dc.date.available","2018-11-07T10:45:55Z"],["dc.date.issued","2004"],["dc.description.abstract","We here report on a case of a blastic tumor, recently described to belong to a new entity sharing phenotypic similarities with blood derived plasmocytoid dendritic cells and formerly regarded as belonging to the group of natural killer cell lymphomas. Besides immunophenotypic characteristics such as the absence of T- cell markers and almost complete absence of markers of the myeloid lineage, these tumors express CD4, CD56 and CD123, the receptor for interleukin-3. Moreover, using the comparative genomic hybridisation technique, CGH, we demonstrate a gain of chromosome 7q, 22 and a loss of chromosome 3p and 13q. Since this type of hematologic disorder often shows its primary manifestation in the skin and often runs a rapidly fatal course, it is important to distinguish this from other types of primary cutaneous lymphomas."],["dc.identifier.isi","000223904100005"],["dc.identifier.pmid","15358570"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/47615"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","John Libbey Eurotext Ltd"],["dc.relation.issn","1167-1122"],["dc.title","CD4+CD56+blastic tumor of the skin: cytogenetic observations and further evidence of an origin from plasmocytoid dendritic cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1107"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","British Journal of Dermatology"],["dc.bibliographiccitation.lastpage","1109"],["dc.bibliographiccitation.volume","164"],["dc.contributor.author","Thoms, Kai Martin"],["dc.contributor.author","Hellriegel, Simin"],["dc.contributor.author","Krone, Bernd"],["dc.contributor.author","Beckmann, I."],["dc.contributor.author","Ritter, K."],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Bertsch, Hans-Peter"],["dc.contributor.author","Kretschmer, Lutz"],["dc.date.accessioned","2018-11-07T08:56:30Z"],["dc.date.available","2018-11-07T08:56:30Z"],["dc.date.issued","2011"],["dc.description.abstract","P>Background Infantile haemangioma (IH) is a tumour of the microvasculature composed predominantly of proliferating endothelial cells. It expresses markers associated with endothelial, haematopoietic and mesenchymal lineages. We have previously shown that the cells forming the capillary endothelium of proliferating IH express cell surface markers and transcriptions factors consistent with it being a haemogenic endothelium. Objectives We wished to determine whether the expression of transcription factors associated with the erythroid lineage was of physiological relevance and sufficient for IH tissue cultured in vitro to undergo erythropoiesis. Methods Immunohistochemical staining of paraffin-embedded sections of proliferating IHs was undertaken and expression of the embryonically associated haemoglobin zeta (HBZ) chain and the erythropoietin receptor (EPO-R) was determined. Relative expression of mRNA encoding these proteins was determined by quantitative reverse transcription-polymerase chain reaction using snap-frozen biopsy samples. Differentiation towards erythrocytes was investigated using freshly resected tissue cultured as explants in Matrigel. Results The endothelium of the microvessels, but not the pericyte layer, was strongly immunoreactive for the EPO-R and the embryonically associated HBZ chain. Abundant expression of transcripts encoding these proteins was also detected, corroborating the immunohistochemical staining. When tissue was grown in culture the cells emanating from IH explants were able to generate enucleated erythrocytes in vitro. The erythrocytes were immunoreactive for the erythrocyte-specific marker glycophorin A. Conclusions The microvessels in IH are a functional haemogenic endothelium that expresses the embryonically associated HBZ chain and is able to form erythrocytes in vitro. IH thus represents a possible extramedullary site for tumour-associated primitive erythropoiesis."],["dc.identifier.doi","10.1111/j.1365-2133.2010.10188.x"],["dc.identifier.isi","000289898200028"],["dc.identifier.pmid","21166659"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23170"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0007-0963"],["dc.title","Successful treatment of classic kaposi sarcoma with low-dose intramuscular immunoglobulins"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","81"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","83"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Claßen, Anna"],["dc.contributor.author","Kitz, Julia"],["dc.contributor.author","Perske, Christina"],["dc.contributor.author","Overbeck, Tobias"],["dc.contributor.author","Bertsch, Hans Peter"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Lippert, Undine"],["dc.date.accessioned","2020-12-10T18:27:17Z"],["dc.date.available","2020-12-10T18:27:17Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1111/ddg.13398"],["dc.identifier.issn","1610-0379"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76294"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Leukemia cutis in a patient with chronic myelomonocytic leukemia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","E21"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Clinical Lymphoma & Myeloma"],["dc.bibliographiccitation.lastpage","E24"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Buhl, Timo"],["dc.contributor.author","Bertsch, Hans P."],["dc.contributor.author","Kaune, Kjell M."],["dc.contributor.author","Mitteldorf, Christina"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Kretschmer, Lutz"],["dc.date.accessioned","2021-06-01T10:48:52Z"],["dc.date.available","2021-06-01T10:48:52Z"],["dc.date.issued","2009"],["dc.identifier.doi","10.3816/CLM.2009.n.079"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86081"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","1557-9190"],["dc.title","Low-Dose Gemcitabine Efficacious in Three Patients With Tumor-Stage Mycosis Fungoides"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","944"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","British Journal of Dermatology"],["dc.bibliographiccitation.lastpage","946"],["dc.bibliographiccitation.volume","167"],["dc.contributor.author","Mitteldorf, Christina"],["dc.contributor.author","Tronnier, Michael"],["dc.contributor.author","Merz, H."],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Bertsch, Hans-Peter"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Kaune, Kjell Matthias"],["dc.date.accessioned","2018-11-07T09:05:19Z"],["dc.date.available","2018-11-07T09:05:19Z"],["dc.date.issued","2012"],["dc.identifier.doi","10.1111/j.1365-2133.2012.10966.x"],["dc.identifier.isi","000309391100034"],["dc.identifier.pmid","22458707"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25290"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0007-0963"],["dc.title","Insect bite-like reactions in a patient with B-cell chronic lymphocytic leukaemia: fluorescence in situ hybridization analysis revealed neoplastic B cells within the skin infiltrate"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","702"],["dc.bibliographiccitation.journal","Allergy"],["dc.bibliographiccitation.lastpage","703"],["dc.bibliographiccitation.volume","65"],["dc.contributor.author","Jung, A."],["dc.contributor.author","Meyer, C."],["dc.contributor.author","Fischer, T."],["dc.contributor.author","Feindt, M."],["dc.contributor.author","Bertsch, Hans-Peter"],["dc.contributor.author","Schoen, M."],["dc.contributor.author","Lippert, Undine"],["dc.date.accessioned","2018-11-07T08:42:22Z"],["dc.date.available","2018-11-07T08:42:22Z"],["dc.date.issued","2010"],["dc.identifier.isi","000329462103472"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19683"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","29th Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI)"],["dc.relation.eventlocation","London, ENGLAND"],["dc.relation.issn","1398-9995"],["dc.relation.issn","0105-4538"],["dc.title","Bullous diffuse cutaneous mastocytosis"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]