Umbach, Nadine

[["dc.contributor.author","Umbach, Nadine"],["dc.contributor.author","Freckmann, Luca"],["dc.contributor.author","Knopp, Cornelius"],["dc.contributor.author","Meyer, Tim"],["dc.contributor.author","Suhr, Markus"],["dc.contributor.author","Kusch, Harald"],["dc.creator.author","Harald Kusch"],["dc.creator.author","Tim Meyer"],["dc.creator.author","Nadine Umbach"],["dc.creator.author","Luca Freckmann"],["dc.creator.author","Cornelius Knopp"],["dc.creator.author","Markus Suhr"],["dc.date.accessioned","2019-10-16T07:34:34Z"],["dc.date.available","2019-10-16T07:34:34Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.3205/18gmds098"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62499"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/224"],["dc.language.iso","en"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.conference","63. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS)"],["dc.relation.eventend","2018"],["dc.relation.eventlocation","Osnabrück"],["dc.relation.eventstart","2018"],["dc.relation.workinggroup","RG Nußbeck"],["dc.relation.workinggroup","RG Zimmermann (Engineered Human Myocardium)"],["dc.title","From seamless acquisition and sustainable management to publication of next-generation sequencing data"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","260"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Biopreservation and Biobanking"],["dc.bibliographiccitation.lastpage","266"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Nussbeck, Sara Y."],["dc.contributor.author","Benson, Erica E."],["dc.contributor.author","Betsou, Fay"],["dc.contributor.author","Guadagni, Fiorella"],["dc.contributor.author","Lehmann, Sabine"],["dc.contributor.author","Umbach, Nadine"],["dc.date.accessioned","2018-11-07T09:19:22Z"],["dc.date.available","2018-11-07T09:19:22Z"],["dc.date.issued","2013"],["dc.identifier.doi","10.1089/bio.2013.1152"],["dc.identifier.isi","000325690600002"],["dc.identifier.pmid","24835256"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28616"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Mary Ann Liebert, Inc"],["dc.relation.issn","1947-5543"],["dc.relation.issn","1947-5535"],["dc.title","Is There a Protocol for Using the SPREC?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","479"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Briefings in Bioinformatics"],["dc.bibliographiccitation.lastpage","487"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Bauer, Christian R."],["dc.contributor.author","Knecht, Carolin"],["dc.contributor.author","Fretter, Christoph"],["dc.contributor.author","Baum, Benjamin"],["dc.contributor.author","Jendrossek, Sandra"],["dc.contributor.author","Ruehlemann, Malte"],["dc.contributor.author","Heinsen, Femke-Anouska"],["dc.contributor.author","Umbach, Nadine"],["dc.contributor.author","Grimbacher, Bodo"],["dc.contributor.author","Franke, Andre"],["dc.contributor.author","Lieb, Wolfgang"],["dc.contributor.author","Krawczak, Michael"],["dc.contributor.author","Huett, Marc-Thorsten"],["dc.contributor.author","Sax, Ulrich"],["dc.date.accessioned","2018-11-07T10:24:26Z"],["dc.date.available","2018-11-07T10:24:26Z"],["dc.date.issued","2017"],["dc.description.abstract","Electronic access to multiple data types, from generic information on biological systems at different functional and cellular levels to high-throughputmolecular data from human patients, is a prerequisite of successful systems medicine research. However, scientists often encounter technical and conceptual difficulties that forestall the efficient and effective use of these resources. We summarize and discuss some of these obstacles, and suggest ways to avoid or evade them. The methodological gap between data capturing and data analysis is huge in human medical research. Primary data producers often do not fully apprehend the scientific value of their data, whereas data analysts maybe ignorant of the circumstances under which the data were collected. Therefore, the provision of easy-to-use data access tools not only helps to improve data quality on the part of the data producers but also is likely to foster an informed dialogue with the data analysts. We propose a means to integrate phenotypic data, questionnaire data and microbiome data with a user-friendly Systems Medicine toolbox embedded into i2b2/tranSMART. Our approach is exemplified by the integration of a basic outlier detection tool and a more advanced microbiome analysis (alpha diversity) script. Continuous discussion with clinicians, data managers, biostatisticians and systems medicine experts should serve to enrich even further the functionality of toolboxes like ours, being geared to be used by 'informed non-experts' but at the same time attuned to existing, more sophisticated analysis tools."],["dc.identifier.doi","10.1093/bib/bbw024"],["dc.identifier.isi","000400968000012"],["dc.identifier.pmid","27016392"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42664"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1477-4054"],["dc.relation.issn","1467-5463"],["dc.title","Interdisciplinary approach towards a systems medicine toolbox using the example of inflammatory diseases"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Information Technology"],["dc.bibliographiccitation.volume","59"],["dc.contributor.author","Baum, Benjamin"],["dc.contributor.author","Bauer, Christian R."],["dc.contributor.author","Franke, Thomas"],["dc.contributor.author","Kusch, Harald"],["dc.contributor.author","Parciak, Marcel"],["dc.contributor.author","Rottmann, Thorsten"],["dc.contributor.author","Umbach, Nadine"],["dc.contributor.author","Sax, Ulrich"],["dc.date.accessioned","2018-04-24T15:08:22Z"],["dc.date.available","2018-04-24T15:08:22Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1515/itit-2016-0031"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/13765"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/176"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.workinggroup","RG Nußbeck"],["dc.title","Opinion paper: Data provenance challenges in biomedical research"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","overview_ja"],["dspace.entity.type","Publication"]]