Now showing 1 - 10 of 31
  • 2018Journal Article
    [["dc.bibliographiccitation.firstpage","102"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","107"],["dc.bibliographiccitation.volume","272"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Willems, Rik"],["dc.contributor.author","Sprenkeler, David J."],["dc.contributor.author","Fischer, Thomas H."],["dc.contributor.author","Flevari, Panayota"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Katsaras, Dimitrios"],["dc.contributor.author","Kirova, Aleksandra"],["dc.contributor.author","Lehnart, Stephan E."],["dc.contributor.author","Lüthje, Lars"],["dc.contributor.author","Röver, Christian"],["dc.contributor.author","Seegers, Joachim"],["dc.contributor.author","Sossalla, Samuel"],["dc.contributor.author","Dunnink, Albert"],["dc.contributor.author","Sritharan, Rajevaa"],["dc.contributor.author","Tuinenburg, Anton E."],["dc.contributor.author","Vandenberk, Bert"],["dc.contributor.author","Vos, Marc A."],["dc.contributor.author","Wijers, Sofieke C."],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Zabel, Markus"],["dc.date.accessioned","2019-07-09T11:50:23Z"],["dc.date.available","2019-07-09T11:50:23Z"],["dc.date.issued","2018"],["dc.description.abstract","BACKGROUND AND OBJECTIVE: We prospectively investigated combinations of risk stratifiers including multiple EP diagnostics in a cohort study of ICD patients. METHODS: For 672 enrolled patients, we collected history, LVEF, EP study and T-wave alternans testing, 24-h Holter, NT-proBNP, and the eGFR. All-cause mortality and first appropriate ICD shock were predefined endpoints. RESULTS: The 635 patients included in the final analyses were 63 ± 13 years old, 81% were male, LVEF averaged 40 ± 14%, 20% were inducible at EP study, 63% had a primary prophylactic ICD. During follow-up over 4.3 ± 1.5 years, 108 patients died (4.0% per year), and appropriate shock therapy occurred in n = 96 (3.9% per year). In multivariate regression, age (p < 0.001), LVEF (p < 0.001), NYHA functional class (p = 0.007), eGFR (p = 0.024), a history of atrial fibrillation (p = 0.011), and NT-pro-BNP (p = 0.002) were predictors of mortality. LVEF (p = 0.002), inducibility at EP study (p = 0.007), and secondary prophylaxis (p = 0.002) were identified as independent predictors of appropriate shocks. A high annualized risk of shocks of about 10% per year was prevalent in the upper quintile of the shock score. In contrast, a low annual risk of shocks (1.8% per year) was found in the lower two quintiles of the shock score. The lower two quintiles of the mortality score featured an annual mortality <0.6%. CONCLUSIONS: In a prospective ICD patient cohort, a very good approximation of mortality versus arrhythmic risk was possible using a multivariable diagnostic strategy. EP stimulation is the best test to assess risk of arrhythmias resulting in ICD shocks."],["dc.identifier.doi","10.1016/j.ijcard.2018.06.103"],["dc.identifier.pmid","29983251"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15929"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59764"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.intern","In goescholar not merged with http://resolver.sub.uni-goettingen.de/purl?gs-1/15360 but duplicate"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/241526/EU//EUTRIGTREAT"],["dc.relation.issn","1874-1754"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.access","openAccess"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.subject.ddc","610"],["dc.subject.mesh","Aged"],["dc.subject.mesh","Aged, 80 and over"],["dc.subject.mesh","Arrhythmias, Cardiac"],["dc.subject.mesh","Cohort Studies"],["dc.subject.mesh","Death, Sudden, Cardiac"],["dc.subject.mesh","Defibrillators"],["dc.subject.mesh","Defibrillators, Implantable"],["dc.subject.mesh","Female"],["dc.subject.mesh","Follow-Up Studies"],["dc.subject.mesh","Humans"],["dc.subject.mesh","Male"],["dc.subject.mesh","Middle Aged"],["dc.subject.mesh","Mortality"],["dc.subject.mesh","Multivariate Analysis"],["dc.subject.mesh","Natriuretic Peptide, Brain"],["dc.subject.mesh","Peptide Fragments"],["dc.subject.mesh","Prospective Studies"],["dc.subject.mesh","Risk Factors"],["dc.title","Differential multivariable risk prediction of appropriate shock versus competing mortality - A prospective cohort study to estimate benefits from ICD therapy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2021Journal Article
    [["dc.bibliographiccitation.journal","Pacing and Clinical Electrophysiology"],["dc.contributor.author","Schlögl, Simon"],["dc.contributor.author","Schlögl, Klaudia Stella"],["dc.contributor.author","Haarmann, Helge"],["dc.contributor.author","Bengel, Philipp"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Rasenack, Eva"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Zabel, Markus"],["dc.date.accessioned","2021-12-01T09:21:15Z"],["dc.date.available","2021-12-01T09:21:15Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1111/pace.14392"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/94387"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-478"],["dc.relation.eissn","1540-8159"],["dc.relation.issn","0147-8389"],["dc.title","Remote magnetic navigation versus manual catheter ablation of atrial fibrillation: A single center long‐term comparison"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article
    [["dc.bibliographiccitation.firstpage","222"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Cardiovascular Computed Tomography"],["dc.bibliographiccitation.lastpage","229"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Sohns, Christian"],["dc.date.accessioned","2021-06-01T10:49:41Z"],["dc.date.available","2021-06-01T10:49:41Z"],["dc.date.issued","2014"],["dc.identifier.doi","10.1016/j.jcct.2014.03.004"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86375"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.issn","1934-5925"],["dc.title","Prevalence of noncardiac findings in computed tomography angiography before transcatheter aortic valve replacement"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","99"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Vascular"],["dc.bibliographiccitation.lastpage","110"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Sohns, Jan M"],["dc.contributor.author","Menke, Jan"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Weiss, Bernhard G"],["dc.contributor.author","Kröhn, Hannah"],["dc.contributor.author","Weiberg, Desiree"],["dc.contributor.author","Derlin, Thorsten"],["dc.contributor.author","Schmuck, Sebastian"],["dc.date.accessioned","2020-12-10T18:38:35Z"],["dc.date.available","2020-12-10T18:38:35Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1177/1708538117724628"],["dc.identifier.eissn","1708-539X"],["dc.identifier.issn","1708-5381"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77377"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Screening of extravascular findings in pulmonary embolism computer tomography: 397 patients with 1950 non-pulmonary artery findings"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","424"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Heart Rhythm"],["dc.bibliographiccitation.lastpage","432"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Backhaus, Sören J."],["dc.contributor.author","Weber-Krüger, Mark"],["dc.contributor.author","Bauer, Lukas"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Lüthje, Lars"],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Bergau, Leonard"],["dc.date.accessioned","2020-12-10T14:24:26Z"],["dc.date.available","2020-12-10T14:24:26Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.hrthm.2018.09.016"],["dc.identifier.issn","1547-5271"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72245"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Reverse left ventricular structural remodeling after catheter ablation of atrial fibrillation in patients with preserved left ventricular function: Insights from cardiovascular magnetic resonance native T1 mapping"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article
    [["dc.bibliographiccitation.journal","Journal of Interventional Cardiac Electrophysiology"],["dc.contributor.author","Schlögl, Simon"],["dc.contributor.author","Schlögl, Klaudia Stella"],["dc.contributor.author","Bengel, Philipp"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Haarmann, Helge"],["dc.contributor.author","Rasenack, Eva"],["dc.contributor.author","Hasenfuss, Gerd"],["dc.contributor.author","Zabel, Markus"],["dc.date.accessioned","2022-09-01T09:49:21Z"],["dc.date.available","2022-09-01T09:49:21Z"],["dc.date.issued","2022"],["dc.description.abstract","Abstract\n \n Background\n In atrial fibrillation (AF) patients, catheter ablation of pulmonary veins (PVI) is the most effective therapeutic option to maintain sinus rhythm. To improve successful PVI, contact force–sensing (CF) catheters became routinely available. Previous studies did not clearly show superior clinical efficacy in comparison with non-CF catheters.\n \n \n Methods\n We investigated consecutive patients, who underwent index PVI for AF at our hospital between 2012 and 2018. Three hundred and fifty-four patients were ablated without CF. After availability of CF catheters in 2016, 317 patients were ablated using CF. In case of crossover between the groups, follow-up was censored. The primary endpoint was any documented atrial tachycardia (AT) or atrial fibrillation > 30 s after a 3-month blanking period. Secondary endpoints were procedural characteristics and periprocedural complications.\n \n \n Results\n \n There was no significant difference between the groups at baseline except hyperlipidemia. After 365 days of follow-up, 67% of patients in the CF group remained free from AF/AT recurrence compared to 59% in non-CF group (\n P\n  = 0.038). In multivariable Cox regression analysis, non-CF ablation was an independent risk factor for AF recurrence besides age and persistent AF. Total fluoroscopy time (15 ± 7.6 vs. 28 ± 15.9 min) and total procedure time (114 ± 29.6 vs. 136 ± 38.5 min) were significantly lower for CF-guided PVI (\n P\n  < 0.001). Complication rates did not differ between groups (\n P\n  = 0.661).\n \n \n \n Conclusions\n In our study, the AT/AF recurrence rate and pulmonary vein reconnection rate is lower after CF PVI with a similar complication rate but lower total procedure time and total fluoroscopy time compared to non-CF PVI."],["dc.identifier.doi","10.1007/s10840-022-01316-8"],["dc.identifier.pii","1316"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113401"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.eissn","1572-8595"],["dc.relation.issn","1383-875X"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Impact of open-irrigated radiofrequency catheter with contact force measurement on the efficacy and safety of atrial fibrillation ablation: a single-center direct comparison"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","27"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Vascular"],["dc.bibliographiccitation.lastpage","38"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Sohns, Jan M"],["dc.contributor.author","Menke, Jan"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Weiss, Bernhard G"],["dc.contributor.author","Schmuck, Sebastian"],["dc.contributor.author","Weiberg, Desiree"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Derlin, Thorsten"],["dc.contributor.author","Dorenkamp, Marc"],["dc.contributor.author","Sohns, Christian"],["dc.date.accessioned","2020-12-10T18:38:34Z"],["dc.date.available","2020-12-10T18:38:34Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1177/1708538117714401"],["dc.identifier.eissn","1708-539X"],["dc.identifier.issn","1708-5381"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77376"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Extra-vascular findings in patients undergoing magnetic resonance angiography of the abdomen, pelvis and lower extremities: A retrospective study of 352 patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","684"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","European Heart Journal - Cardiovascular Imaging"],["dc.bibliographiccitation.lastpage","691"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Luethje, Lars"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Dorenkamp, Marc"],["dc.contributor.author","Zwaka, Paul A."],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Zabel, Markus"],["dc.date.accessioned","2017-09-07T11:47:40Z"],["dc.date.available","2017-09-07T11:47:40Z"],["dc.date.issued","2013"],["dc.description.abstract","Aims This study aimed to identify whether left atrial (LA) volume assessed by multidetector computed tomography (MDCT) is related to the long-term success of pulmonary vein ablation (PVA). MDCT is used to guide PVA for the treatment of atrial fibrillation (AF). MDCT permits accurate sizing of LA dimensions. Methods and results We analysed data from 368 ablation procedures of 279 consecutive patients referred for PVA due to drug-refractory symptomatic AF (age 62 +/- 10; 58% men; 71% paroxysmal AF). Prior to the procedure, all patients underwent ECG-gated 64-MDCT scan for assessment of LA and PV anatomy, LA thrombus evaluation, LA volume estimation, and electroanatomical mapping integration. Within a mean follow-up of 356 +/- 128 days, 64% of the patients maintained sinus rhythm after the initial ablation, and 84% when including repeat PVA. LA diameter (P = 0.004), LA volume (P = 0.002), and type of AF (P = 0.001) were independent predictors of AF recurrence in univariate analysis. There was a relatively low correlation between the echocardiographic LA diameter and LA volume from MDCT (P = 0.01, r = 0.5). In multivariate analysis, paroxysmal AF (P < 0.006) and LA volume below the median value of 106 mL (P = 0.042) were significantly associated with the success of PVA, whereas LA diameter was not (P = 0.245). Analysing receiver-operator characteristics, the area under the curve for LA volume was 0.73 (P = 0.001) compared with 0.60 (P = 0.09) for LA diameter from echocardiography. Conclusion LA volume assessed by MDCT is a better predictor of AF recurrence after PVA than echocardiograpic LA diameter and can be derived from the pre-procedural imaging data set."],["dc.identifier.doi","10.1093/ehjci/jet017"],["dc.identifier.gro","3142334"],["dc.identifier.isi","000321462600013"],["dc.identifier.pmid","23435593"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7131"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","2047-2404"],["dc.title","Left atrial volumetry from routine diagnostic work up prior to pulmonary vein ablation is a good predictor of freedom from atrial fibrillation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article
    [["dc.bibliographiccitation.firstpage","647"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","The International Journal of Cardiovascular Imaging"],["dc.bibliographiccitation.lastpage","657"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Hinojar, Rocio"],["dc.contributor.author","Dorenkamp, Marc"],["dc.contributor.author","Obenauer, Silvia"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Sohns, Christian"],["dc.date.accessioned","2018-11-07T09:43:08Z"],["dc.date.available","2018-11-07T09:43:08Z"],["dc.date.issued","2014"],["dc.description.abstract","We sought to evaluate the diagnostic accuracy of contrast-enhanced cardiac magnetic resonance (CMR) imaging for the detection of intracardiac masses and thrombus formation in patients with history of coronary artery disease (CAD) in comparison to transthoracic echocardiography (TTE) under clinical routine conditions. 171 patients with history of CAD (89 male, aged 34-89 years, median 63 +/- A 11) underwent TTE and CMR during routine clinical examinations. TTE and CMR were independently analysed regarding the presence of intracardiac thrombus formation, masses and related size, dimensions, shape and signal characteristics. TTE depicted intracavitary thrombus formation in 40/171 patients (23.4 %) and intracardiac mass in 12/171 patients (7.0 %). All masses revealed in TTE were correctly detected on CMR and confirmed by histology. However, CMR showed 15 additional thrombi and 3 additional intracardiac masses (p = 0.001) that were not seen in TTE. Patients with poor systolic function (LVEF < 30 %) had misleading results when referred to TTE (19 vs. 27 thrombi detected, p < 0.01). The detection of intracardiac masses or thrombi was not significantly different in patient with LVEF > 30 %, whereas CMR was superior when the LVEF was < 30 %. Routine TTE in patients with CAD leads to lower detection rates of intracardiac masses and thrombus formation in patients with severely impaired EF. Consequently we are missing a significant amount of clinically relevant diagnosis when only assessing patients with TTE. In patients with CAD and severely impaired LVEF, CMR should be considered as first line imaging tool to detect or rule out intracardiac masses and thrombi."],["dc.identifier.doi","10.1007/s10554-013-0357-9"],["dc.identifier.isi","000333212900021"],["dc.identifier.pmid","24384859"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34110"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1573-0743"],["dc.relation.issn","1569-5794"],["dc.title","Detection of intracardiac masses in patients with coronary artery disease using cardiac magnetic resonance imaging: a comparison with transthoracic echocardiography"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","963"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","EP Europace"],["dc.bibliographiccitation.lastpage","970"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Sticherling, Christian"],["dc.contributor.author","Arendacka, Barbora"],["dc.contributor.author","Svendsen, Jesper Hastrup"],["dc.contributor.author","Wijers, Sofieke"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Stockinger, Jochem"],["dc.contributor.author","Dommasch, Michael"],["dc.contributor.author","Merkely, Bela"],["dc.contributor.author","Willems, Rik"],["dc.contributor.author","Lubinski, Andrzej"],["dc.contributor.author","Scharfe, Michael"],["dc.contributor.author","Braunschweig, Frieder"],["dc.contributor.author","Svetlosak, Martin"],["dc.contributor.author","Zürn, Christine S"],["dc.contributor.author","Huikuri, Heikki"],["dc.contributor.author","Flevari, Panagiota"],["dc.contributor.author","Lund-Andersen, Caspar"],["dc.contributor.author","Schaer, Beat A"],["dc.contributor.author","Tuinenburg, Anton E"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Schmidt, Georg"],["dc.contributor.author","Szeplaki, Gabor"],["dc.contributor.author","Vandenberk, Bert"],["dc.contributor.author","Kowalczyk, Emilia"],["dc.contributor.author","Eick, Christian"],["dc.contributor.author","Juntilla, Juhani"],["dc.contributor.author","Conen, David"],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Aaboud, M. et al. (ATLAS Collaboration)"],["dc.date.accessioned","2021-11-22T14:31:38Z"],["dc.date.available","2021-11-22T14:31:38Z"],["dc.date.issued","2017"],["dc.description.abstract","Aims Therapy with an implantable cardioverter defibrillator (ICD) is established for the prevention of sudden cardiac death (SCD) in high risk patients. We aimed to determine the effectiveness of primary prevention ICD therapy by analysing registry data from 14 centres in 11 European countries compiled between 2002 and 2014, with emphasis on outcomes in women who have been underrepresented in all trials. Methods and results Retrospective data of 14 local registries of primary prevention ICD implantations between 2002 and 2014 were compiled in a central database. Predefined primary outcome measures were overall mortality and first appropriate and first inappropriate shocks. A multivariable model enforcing a common hazard ratio for sex category across the centres, but allowing for centre-specific baseline hazards and centre specific effects of other covariates, was adjusted for age, the presence of ischaemic cardiomyopathy or a CRT-D, and left ventricular ejection fraction ≤25%. Of the 5033 patients, 957 (19%) were women. During a median follow-up of 33 months (IQR 16–55 months) 129 women (13%) and 807 men (20%) died (HR 0.65; 95% CI: [0.53, 0.79], P-value < 0.0001). An appropriate ICD shock occurred in 66 women (8%) and 514 men (14%; HR 0.61; 95% CI: 0.47–0.79; P = 0.0002). Conclusion Our retrospective analysis of 14 local registries in 11 European countries demonstrates that fewer women than men undergo ICD implantation for primary prevention. After multivariate adjustment, women have a significantly lower mortality and receive fewer appropriate ICD shocks."],["dc.identifier.doi","10.1093/europace/eux176"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15529"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/93395"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation","info:eu-repo/grantAgreement/EC/FP7/602299/EU//EU-CERT-ICD"],["dc.relation.issn","1532-2092"],["dc.relation.issn","1099-5129"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.title","Sex differences in outcomes of primary prevention implantable cardioverter-defibrillator therapy: combined registry data from eleven European countries"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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