Roder, Sascha

[["dc.bibliographiccitation.artnumber","403"],["dc.bibliographiccitation.firstpage","403"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Infectious Diseases"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Dopfer-Jablonka, Alexandra"],["dc.contributor.author","Steffens, Sandra"],["dc.contributor.author","Müller, Frank"],["dc.contributor.author","Mikuteit, Marie"],["dc.contributor.author","Niewolik, Jacqueline"],["dc.contributor.author","Cossmann, Anne"],["dc.contributor.author","Stankov, Metodi V."],["dc.contributor.author","Behrens, Georg M. N."],["dc.contributor.author","Hummers, Eva"],["dc.contributor.author","Heesen, Gloria"],["dc.contributor.author","Schröder, Dominik"],["dc.contributor.author","Roder, Sascha"],["dc.contributor.author","Klawonn, Frank"],["dc.contributor.author","Vahldiek, Kai"],["dc.contributor.author","Hasenkamp, Justin"],["dc.contributor.author","Kallusky, Jonathan"],["dc.contributor.author","Falk, Christine S."],["dc.contributor.author","Overbeck, Tobias R."],["dc.contributor.author","Heinemann, Stephanie"],["dc.date.accessioned","2022-04-29T07:33:23Z"],["dc.date.accessioned","2022-08-12T12:57:45Z"],["dc.date.available","2022-04-29T07:33:23Z"],["dc.date.available","2022-08-12T12:57:45Z"],["dc.date.issued","2022-04-25"],["dc.date.updated","2022-07-29T12:00:25Z"],["dc.description.abstract","Background\r\n Immunocompromised people (ICP) and elderly individuals (older than 80 years) are at increased risk for severe coronavirus infections. To protect against serious infection with SARS-CoV-2, ICP are taking precautions that may include a reduction of social contacts and participation in activities which they normally enjoy. Furthermore, for these people, there is an uncertainty regarding the effectiveness of the vaccination. The COVID-19 Contact (CoCo) Immune study strives to characterize the immune response to COVID-19 vaccination in immunocompromised, elderly people, and patients with hematological or oncological diseases. The study uses blood-based screenings to monitor the humoral and cellular immune response in these groups after vaccination. Questionnaires and qualitative interviews are used to describe the level of social participation.\r\n \r\n \r\n Methods\r\n The CoCo Immune Study is a mixed methods prospective, longitudinal, observational study at two large university hospitals in Northern Germany. Starting in March 2021, it monitors anti-SARS-CoV-2 immune responses and collects information on social participation in more than 600 participants, at least 18 years old. Inclusion criteria and subcohorts: Participants with (1) regularly intake of immunosuppressive medication (ICP-cohort) or (2) age ≥ 80 years (80 + -cohort). Additionally, patients with current or former (3) myeloid, (4) lymphatic disease or (5) solid tumor under checkpoint inhibition (3–5: HO-cohort). Exclusion criteria: (1) refusal to give informed consent, (2) contraindication to blood testing, (3) inability to declare consent. Participants complete a questionnaire at four different time points: prior to full vaccination, and 1, 6 and 12 months after completed vaccination. In addition, participants draw blood samples themselves or through a local health care provider and send them with their questionnaires per post at the respective time points after vaccination. Patients of the HO cohort dispense additional blood samples at week 3 to 12 and at month 6 to 9 after 2nd vaccination to gain additional knowledge in B and T cell responses. Selected participants are invited to qualitative interviews about social participation.\r\n \r\n \r\n Discussion\r\n This observational study is designed to gain insight into the immune response of people with weakened immune systems and to find out how social participation is affected after COVID-19 vaccination.\r\n Trial registration: This study was registered with German Clinical Trial Registry (registration number: DRKS00023972) on 30th December 2020."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.citation","BMC Infectious Diseases. 2022 Apr 25;22(1):403"],["dc.identifier.doi","10.1186/s12879-022-07347-w"],["dc.identifier.pmid","35468758"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/106987"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/112723"],["dc.language.iso","en"],["dc.relation","DEFEnse Against COVID-19 STudy"],["dc.relation.eissn","1471-2334"],["dc.relation.issn","1471-2334"],["dc.relation.orgunit","Institut für Allgemeinmedizin"],["dc.rights","CC BY 4.0"],["dc.rights.holder","The Author(s)"],["dc.subject","SARS-CoV-2"],["dc.subject","COVID-19"],["dc.subject","Pandemic"],["dc.subject","Humoral and cellular immunity"],["dc.subject","Immunocompromised people"],["dc.subject","Elderly"],["dc.subject","Hematology"],["dc.subject","Solid tumor"],["dc.subject","Checkpoint inhibition"],["dc.subject","Serological testing"],["dc.subject","Coronavirus"],["dc.subject","Social participation"],["dc.subject","Immunogenicity"],["dc.title","SARS-CoV-2-specific immune responses in elderly and immunosuppressed participants and patients with hematologic disease or checkpoint inhibition in solid tumors: study protocol of the prospective, observational CoCo immune study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","82"],["dc.bibliographiccitation.issue","1-2"],["dc.bibliographiccitation.journal","Siegen: sozial"],["dc.bibliographiccitation.lastpage","87"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Roder, Sascha"],["dc.date.accessioned","2021-12-16T13:09:11Z"],["dc.date.available","2021-12-16T13:09:11Z"],["dc.date.issued","2021-12"],["dc.description.abstract","Human - Machine - Participation. On the Success and the Shortcomings of the Hearing Prosthesis Cochlear Implant The recovery of hearing in deafness or profound hearing loss after a cochlear implant is nowadays the rule rather than the exception. However, next to the multiple success with the hearing prosthesis and the associated gain in freedom in professional, social and cultural participation, the person concerned encounter serious challenges. Many of those who have received a hearing prosthesis are burdened by years of strenuous practice in learning to understand with the cochlear implant. Beside this, cochlear users experience after-effects due to the implant surgery such as tinnitus, dizziness or impaired balance. Furthermore, they face a dependence on the few existing medical and technical experts for the care of their hearing prosthesis and a lack of local care concepts for necessary therapeutic support. They also meet various hearing barriers in their everyday life. People at an advanced age currently play a particularly important role due to the high number of fittings. In a reconstructive study, more than 70 people with a cochlear implant were interviewed by means of a guideline interview on their personal experiences with the operating clinics and their newly experienced social, cultural and professional participation in society. The results which were evaluated with the qualitative content analysis showed, on one hand, outstanding improvements in the communicative processes in the users’ direct surroundings. However, on the other hand, the high demands placed on the mastery of technology and a comprehensive personal responsibility in dealing with the hearing comprehension with the prosthesis, which was perceived as disconcerting, led to considerable burdens. This clearly showed the limits of human-machine-interaction."],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/96978"],["dc.language.iso","en"],["dc.relation.issn","0949-5673"],["dc.relation.orgunit","Institut für Allgemeinmedizin"],["dc.title","Human-Machine-Participation. On the success and shortcomings oft he hearing prosthesis cochlear implant."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Die Rehabilitation"],["dc.contributor.author","Roder, Sascha"],["dc.contributor.author","Strünck, Christoph"],["dc.date.accessioned","2022-04-01T10:00:41Z"],["dc.date.available","2022-04-01T10:00:41Z"],["dc.date.issued","2022"],["dc.description.abstract","Ziel der Studie Cochlea-Implantate können Menschen mit einer erworbenen, progredient verlaufenden Ertaubung helfen, ihr Hörvermögen wiederzuerlangen. Die betroffenen Personen durchleben allerdings auch einen jahrelangen Prozess der Adaptation, in dem sie ein neues, technisch unterstütztes Hören lernen müssen. Die Studie zeigt, wie Betroffene diesen Prozess erleben und ob ihre Erwartungen an das Implantat erfüllt werden. Methodik Im Rahmen einer qualitativen Studie wurden 50 Cochlea-Implantat-Träger innen in einem Leitfaden-gestützten Interview befragt. 30 Personen wurden über den Kontakt zu Selbsthilfegruppen rekrutiert, weitere 20 Personen über ein Hörzentrum nach Vermittlung durch einen leitenden Audiologen. Die Interviewten gaben Auskunft über ihre persönlichen Erfahrungen mit den operierenden Kliniken, über das Erleben der sozialen, kulturellen und beruflichen Teilhabe sowie über die auch nach der CI-Versorgung bestehenden Hörbarrieren im Alltag. Die Befragten trugen die Hörprothese maximal drei Jahre, ein Zeitrahmen, innerhalb dessen die meisten der Folgetherapien beendet sind und der initiale Lernprozess mit dem CI als abgeschlossen gilt. Ergebnisse Auch mit einem Cochlea-Implantat bleiben Kommunikationshindernisse bestehen. Erwartungen eines vollen Hörverstehens im Freundes- und Bekanntenkreis werden nur bedingt erfüllt. Schwierigkeiten im Umgang mit einer hochtechnisierten Hörprothese sowie das Erleben als „Fremdkörper“ erschweren die Akzeptanz eines CIs. Schlussfolgerung Die Beratung in der Versorgung mit Cochlea-Implantaten sollte sich an realistischen Zielen und Erwartungen orientieren. Die Versorgung mit einem CI lässt sich verbessern, wenn angeleitete Hörtrainings und Kommunikationsangebote ausgeweitet werden. Auch können ortsnahe Versorgungsstrukturen wie zum Beispiel über zertifizierte Hörakustiker einbezogen werden und dabei helfen, Unsicherheiten abzubauen."],["dc.identifier.doi","10.1055/a-1723-1854"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/105489"],["dc.language.iso","de"],["dc.notes.intern","DOI-Import GROB-530"],["dc.relation.eissn","1439-1309"],["dc.relation.issn","0034-3536"],["dc.relation.orgunit","Institut für Allgemeinmedizin"],["dc.title","Mehr soziale Teilhabe für Hörgeschädigte durch Cochlea-Implantate? Zur Ambivalenz der Mensch-Maschine-Interaktion und zum Stellenwert psycho-sozialer Begleitung"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]