Now showing 1 - 10 of 39
  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","134"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Der Gynäkologe"],["dc.bibliographiccitation.lastpage","138"],["dc.bibliographiccitation.volume","50"],["dc.contributor.author","Artelt, Tanja"],["dc.contributor.author","Kaase, Martin"],["dc.contributor.author","Scheithauer, Simone"],["dc.date.accessioned","2020-12-10T14:08:43Z"],["dc.date.available","2020-12-10T14:08:43Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00129-016-4011-1"],["dc.identifier.eissn","1433-0393"],["dc.identifier.issn","0017-5994"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70529"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Infektiologische Herausforderungen nach Migration"],["dc.title.alternative","Challenges regarding infectious diseases in migrants. Special aspects in the care of female refugees"],["dc.title.subtitle","Besonderheiten bei der Betreuung weiblicher Flüchtlinge"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article Research Paper
    [["dc.bibliographiccitation.firstpage","689"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Antibiotics"],["dc.bibliographiccitation.volume","11"],["dc.contributor.affiliation","Pankok, Frederik; 1Institute for Infection Control and Infectious Diseases, University Medical Center Göttingen, 37075 Göttingen, Germany; frederik.pankok@med.uni-goettingen.de (F.P.); stefan.taudien@med.uni-goettingen.de (S.T.); martin.kaase@med.uni-goettingen.de (M.K.); simone.scheithauer@med.uni-goettingen.de (S.S.)"],["dc.contributor.affiliation","Taudien, Stefan; 1Institute for Infection Control and Infectious Diseases, University Medical Center Göttingen, 37075 Göttingen, Germany; frederik.pankok@med.uni-goettingen.de (F.P.); stefan.taudien@med.uni-goettingen.de (S.T.); martin.kaase@med.uni-goettingen.de (M.K.); simone.scheithauer@med.uni-goettingen.de (S.S.)"],["dc.contributor.affiliation","Dekker, Denise; 2Department of Implementation Research, Bernhard Nocht Institute for Tropical Medicine Hamburg, 20359 Hamburg, Germany; dekker@bnitm.de"],["dc.contributor.affiliation","Thye, Thorsten; 3Department of Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine Hamburg, 20359 Hamburg, Germany; thye@bnitm.de (T.T.); lamshoeft@bnitm.de (M.L.); anna.jaeger@bnitm.de (A.J.); may@bnitm.de (J.M.)"],["dc.contributor.affiliation","Oppong, Kwabena; 4Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi 039-5028, Ghana; Oppong.kwabena@presbyuniversity.edu.gh (K.O.); danquah@kccr.de (C.W.A.)"],["dc.contributor.affiliation","Wiafe Akenten, Charity; 4Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi 039-5028, Ghana; Oppong.kwabena@presbyuniversity.edu.gh (K.O.); danquah@kccr.de (C.W.A.)"],["dc.contributor.affiliation","Lamshöft, Maike; 3Department of Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine Hamburg, 20359 Hamburg, Germany; thye@bnitm.de (T.T.); lamshoeft@bnitm.de (M.L.); anna.jaeger@bnitm.de (A.J.); may@bnitm.de (J.M.)"],["dc.contributor.affiliation","Jaeger, Anna; 3Department of Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine Hamburg, 20359 Hamburg, Germany; thye@bnitm.de (T.T.); lamshoeft@bnitm.de (M.L.); anna.jaeger@bnitm.de (A.J.); may@bnitm.de (J.M.)"],["dc.contributor.affiliation","Kaase, Martin; 1Institute for Infection Control and Infectious Diseases, University Medical Center Göttingen, 37075 Göttingen, Germany; frederik.pankok@med.uni-goettingen.de (F.P.); stefan.taudien@med.uni-goettingen.de (S.T.); martin.kaase@med.uni-goettingen.de (M.K.); simone.scheithauer@med.uni-goettingen.de (S.S.)"],["dc.contributor.affiliation","Scheithauer, Simone; 1Institute for Infection Control and Infectious Diseases, University Medical Center Göttingen, 37075 Göttingen, Germany; frederik.pankok@med.uni-goettingen.de (F.P.); stefan.taudien@med.uni-goettingen.de (S.T.); martin.kaase@med.uni-goettingen.de (M.K.); simone.scheithauer@med.uni-goettingen.de (S.S.)"],["dc.contributor.affiliation","Tanida, Konstantin; 6Department of Microbiology and Hospital Hygiene, Bundeswehr Hospital Hamburg, External Site at the Bernhard Nocht Institute for Tropical Medicine Hamburg, 20359 Hamburg, Germany; Konstantin.tanida@gmail.com (K.T.); frickmann@bnitm.de (H.F.)"],["dc.contributor.affiliation","Frickmann, Hagen; 6Department of Microbiology and Hospital Hygiene, Bundeswehr Hospital Hamburg, External Site at the Bernhard Nocht Institute for Tropical Medicine Hamburg, 20359 Hamburg, Germany; Konstantin.tanida@gmail.com (K.T.); frickmann@bnitm.de (H.F.)"],["dc.contributor.affiliation","May, Jürgen; 3Department of Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine Hamburg, 20359 Hamburg, Germany; thye@bnitm.de (T.T.); lamshoeft@bnitm.de (M.L.); anna.jaeger@bnitm.de (A.J.); may@bnitm.de (J.M.)"],["dc.contributor.affiliation","Loderstädt, Ulrike; 1Institute for Infection Control and Infectious Diseases, University Medical Center Göttingen, 37075 Göttingen, Germany; frederik.pankok@med.uni-goettingen.de (F.P.); stefan.taudien@med.uni-goettingen.de (S.T.); martin.kaase@med.uni-goettingen.de (M.K.); simone.scheithauer@med.uni-goettingen.de (S.S.)"],["dc.contributor.author","Pankok, Frederik"],["dc.contributor.author","Taudien, Stefan"],["dc.contributor.author","Dekker, Denise"],["dc.contributor.author","Thye, Thorsten"],["dc.contributor.author","Oppong, Kwabena"],["dc.contributor.author","Wiafe Akenten, Charity"],["dc.contributor.author","Lamshöft, Maike"],["dc.contributor.author","Jaeger, Anna"],["dc.contributor.author","Kaase, Martin"],["dc.contributor.author","Scheithauer, Simone"],["dc.contributor.author","Loderstädt, Ulrike"],["dc.contributor.author","Tanida, Konstantin"],["dc.contributor.author","Frickmann, Hagen"],["dc.contributor.author","May, Jürgen"],["dc.date.accessioned","2022-06-01T09:39:55Z"],["dc.date.available","2022-06-01T09:39:55Z"],["dc.date.issued","2022"],["dc.date.updated","2022-06-05T19:53:00Z"],["dc.description.abstract","Little information is available on the local epidemiology of mobile genetic elements such as plasmids harboring acquired beta-lactamase genes in Western African Ghana. In the present study, we screened for plasmids in three Escherichia coli and four Klebsiella pneumoniae isolates expressing extended spectrum beta-lactamases (ESBL) mediated by the blaCTX-M-15 gene from chronically infected wounds of Ghanaian patients. Bacterial isolates were subjected to combined short-read and long-read sequencing to obtain the sequences of their respective plasmids. In the blaCTX-M-15-gene-carrying plasmids of the four ESBL-positive K. pneumoniae isolates, IncFIB/IncFII (n = 3) and FIA (n = 1) sequences were detected, while in the blaCTX-M-15-gene-carrying plasmids of the three ESBL-positive E. coli isolates, IncFIA/IncFIB (n = 2) and IncFIB (n = 1) sequences were found. The three IncFIB/IncFII sequence-containing plasmids were almost identical to a K. pneumoniae plasmid reported from France. They belonged to the clonal lineages ST17, ST36 and ST39 of K. pneumoniae, suggesting transversal spread of this obviously evolutionary successful plasmid in Ghana. Other resistance gene-encoding plasmids observed in the assessed Enterobacterales harbored IncFIA/IncR and IncFII sequences. International spread was confirmed by the high genetic similarity to resistance-mediating plasmids published from Asia, Australia, Europe and Northern America, including a blaCTX-M-15-gene-carrying plasmid isolated from a wild bird in Germany. In conclusion, the study contributed to the scarcely available information on the epidemiology of third-generation cephalosporine resistance-mediating plasmids in Ghana. Furthermore, the global spread of resistance-mediating plasmids provided hints on the evolutionary success of individual resistance-harboring plasmids by transversal spread among K. pneumoniae lineages in Ghana."],["dc.description.sponsorship","Bernhard Nocht Institute for Tropical Medicine (BNITM)"],["dc.description.sponsorship","Open-Access-Publikationsfonds 2022"],["dc.identifier.doi","10.3390/antibiotics11050689"],["dc.identifier.pii","antibiotics11050689"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/108594"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/108722"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-572"],["dc.relation.eissn","2079-6382"],["dc.rights","CC BY 4.0"],["dc.title","Epidemiology of Plasmids in Escherichia coli and Klebsiella pneumoniae with Acquired Extended Spectrum Beta-Lactamase Genes Isolated from Chronic Wounds in Ghana"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]
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  • 2018Journal Article
    [["dc.bibliographiccitation.firstpage","634"],["dc.bibliographiccitation.issue","09"],["dc.bibliographiccitation.journal","Deutsche medizinische Wochenschrift"],["dc.bibliographiccitation.lastpage","642"],["dc.bibliographiccitation.volume","143"],["dc.contributor.author","Scheithauer, Simone"],["dc.contributor.author","Kaase, Martin"],["dc.date.accessioned","2020-12-10T18:12:26Z"],["dc.date.available","2020-12-10T18:12:26Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1055/s-0043-115622"],["dc.identifier.eissn","1439-4413"],["dc.identifier.issn","0012-0472"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74372"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Prävention und Diagnostik multiresistenter Erreger"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.firstpage","765"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Der Anaesthesist"],["dc.bibliographiccitation.lastpage","777"],["dc.bibliographiccitation.volume","64"],["dc.contributor.author","Bauer, M."],["dc.contributor.author","Scheithauer, Simone"],["dc.contributor.author","Moerer, Onnen"],["dc.contributor.author","Puetz, H."],["dc.contributor.author","Sliwa, Bodo"],["dc.contributor.author","Schmidt, C. E."],["dc.contributor.author","Russo, Sebastian Giuseppe"],["dc.contributor.author","Waeschle, Reiner M."],["dc.date.accessioned","2018-11-07T09:50:46Z"],["dc.date.available","2018-11-07T09:50:46Z"],["dc.date.issued","2015"],["dc.description.abstract","Background. The assurance of high standards of care is a major requirement in German hospitals while cost reduction and efficient use of resources are mandatory. These requirements are particularly evident in the high-risk and cost-intensive operating theatre field with multiple process steps. The cleaning of operating rooms (OR) between surgical procedures is of major relevance for patient safety and requires time and human resources. The hygiene procedure plan for OR cleaning between operations at the university hospital in Gottingen was revised and optimized according to the plan-do-check-act principle due to not clearly defined specifications of responsibilities, use of resources, prolonged process times and increased staff engagement. Methods. The current status was evaluated in 2012 as part of the first step \"plan\". The subsequent step \"do\" included an expert symposium with external consultants, interdisciplinary consensus conferences with an actualization of the former hygiene procedure plan and the implementation process. All staff members involved were integrated into this management change process. The penetration rate of the training and information measures as well as the acceptance and compliance with the new hygiene procedure plan were reviewed within step \"check\". The rates of positive swabs and air sampling as well as of postoperative wound infections were analyzed for quality control and no evidence for a reduced effectiveness of the new hygiene plan was found. After the successful implementation of these measures the next improvement cycle (\"act\") was performed in 2014 which led to a simplification of the hygiene plan by reduction of the number of defined cleaning and disinfection programs for preparation of the OR. Results. The reorganization measures described led to a comprehensive commitment of the hygiene procedure plan by distinct specifications for responsibilities, for the course of action and for the use of resources. Furthermore, a simplification of the plan, a rational staff assignment and reduced process times were accomplished. Finally, potential conflicts due to an insufficient evidence-based knowledge of personnel was reduced. Conclusion. This present project description can be used by other hospitals as a guideline for similar changes in management processes."],["dc.identifier.doi","10.1007/s00101-015-0086-7"],["dc.identifier.isi","000363241800009"],["dc.identifier.pmid","26428000"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35777"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-055X"],["dc.relation.issn","0003-2417"],["dc.title","Implementation of a rational standard of hygiene for preparation of operating rooms"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2022Journal Article
    [["dc.bibliographiccitation.journal","Journal of Neurological Surgery Part A: Central European Neurosurgery"],["dc.contributor.author","Abboud, Tammam"],["dc.contributor.author","Melich, Patrick"],["dc.contributor.author","Scheithauer, S"],["dc.contributor.author","Rohde, Veit"],["dc.contributor.author","Schatlo, Bawarjan"],["dc.date.accessioned","2022-04-01T10:01:47Z"],["dc.date.available","2022-04-01T10:01:47Z"],["dc.date.issued","2022"],["dc.description.abstract","Objective: Infectious spondylodiscitis is a heterogeneous disease usually affecting a fragile patient population with multiple comorbidities. Therefore, surgical and medical complications are important considerations before initiating treatment. Methods: This retrospective analysis included data of 218 patients who underwent surgical treatment for pyogenic spondylodiscitis between 2008 and 2016. Groups were divided into length of hospital stay (LOS) of >21 days (Group I =<21 days, Group II > 21days). Analysis included patient age, gender, Charlson Comorbidity Index, smoking, obesity, osteoporosis, colonization with multidrug-resistant bacteria, preoperative neurological deficit, pre- und postoperative inflammation markers (CRP and WBC), duration of surgery, number of operated segments, vertebrectomy, postoperative medical and surgical complications. The case value for each patient expressed in Euro was retrieved from hospital records and included in the analysis. Results: Duration of stay after surgical treatment of spondylodiscitis was =<21 days (4 to 21, mean 16 days) in 41% and > 21 days (22 to 162, mean 41 days) in 59% of the patients. Multivariate analysis showed that both medical complications (OR 2.62, 95% CI 1.24-5.56, p=0.012) and surgical site infection (OR 6.04, 95% CI 2.35-15.51, p<0.001) were independently associated with a long hospital stay. Case values averaged at 21,667 ± 1,579 Euro (min: 2,888 and max: 203,802 Euro) and correlated significantly with the length of hospital stay (Pearson correlation coefficient 0.681, p<0.05). The occurrence of a postoperative complication increased the cost of care significantly from 17,790 to 24,527 Euro on average (p=0.025). Conclusions: This study provides benchmark data for patients treated surgically for spondylodiscitis. Surgical site infection and medical complications are the main drivers of prolonged hospital stays and cost of care."],["dc.identifier.doi","10.1055/a-1811-7633"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/105749"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-530"],["dc.relation.eissn","2193-6323"],["dc.relation.issn","2193-6315"],["dc.title","Complications, length of hospital stay and cost of care after surgery for pyogenic spondylodiscitis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","321"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Hospital Infection"],["dc.bibliographiccitation.lastpage","327"],["dc.bibliographiccitation.volume","103"],["dc.contributor.author","Fehling, P."],["dc.contributor.author","Hasenkamp, J."],["dc.contributor.author","Unkel, S."],["dc.contributor.author","Thalmann, I."],["dc.contributor.author","Hornig, S."],["dc.contributor.author","Trümper, L."],["dc.contributor.author","Scheithauer, S."],["dc.date.accessioned","2020-12-10T14:25:09Z"],["dc.date.available","2020-12-10T14:25:09Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.jhin.2019.06.004"],["dc.identifier.issn","0195-6701"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72459"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Effect of gloved hand disinfection on hand hygiene before infection-prone procedures on a stem cell ward"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","112"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie"],["dc.bibliographiccitation.lastpage","120"],["dc.bibliographiccitation.volume","51"],["dc.contributor.author","Reichard, Utz"],["dc.contributor.author","Rettkowski, Renate"],["dc.contributor.author","Scheithauer, Simone"],["dc.date.accessioned","2018-11-07T10:18:30Z"],["dc.date.available","2018-11-07T10:18:30Z"],["dc.date.issued","2016"],["dc.description.abstract","Zusammenfassung Multiresistente Keime spielen im klinischen Alltag eine zunehmend bedeutsame Rolle. Dieses besonders auf Intensivstationen bzw. in Risikobereichen. Oftmals herrschen Unklarheiten bezuglich diagnostischer Screening-Indikationen und Strategien zur Vermeidung von ubertragungen mittels Hygiene- und Isolierungsma ss nahmen. Wir geben einen orientierenden uberblick uber die zur Zeit gangigen Empfehlungen und bewerten diese fur Methicillin-resistente Staphylococcusaureus-Stamme (MRSA) und multiresistente gramnegative Bakterien (MRGN). Abstract Multiresistant bacteria play an increasingly important role in everyday clinical practice. This is particularly the case in intensive care units and wards with critically ill patients. Often there is insufficient knowledge concerning diagnostic screening indications and strategies to avoid cross-transmission via infection control strategies. Hereby, we provide an orienting overview and assessment about current guidelines and recommendations with special focus on methicillin-resistant Staphylococcus aureus (MRSA) and multiresistantgramnegative bacteria (MRGN)."],["dc.identifier.doi","10.1055/s-0041-103142"],["dc.identifier.isi","000371904700006"],["dc.identifier.pmid","26949906"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41458"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Georg Thieme Verlag Kg"],["dc.relation.issn","1439-1074"],["dc.relation.issn","0939-2661"],["dc.title","Multiresistant Pathogen Prevention and Diagnosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2018Journal Article
    [["dc.bibliographiccitation.firstpage","e66"],["dc.bibliographiccitation.issue","S 01"],["dc.bibliographiccitation.journal","Methods of Information in Medicine"],["dc.bibliographiccitation.lastpage","e81"],["dc.bibliographiccitation.volume","57"],["dc.contributor.author","Haarbrandt, Birger"],["dc.contributor.author","Schreiweis, Björn"],["dc.contributor.author","Rey, Sabine"],["dc.contributor.author","Sax, Ulrich"],["dc.contributor.author","Scheithauer, Simone"],["dc.contributor.author","Rienhoff, Otto"],["dc.contributor.author","Knaup-Gregori, Petra"],["dc.contributor.author","Bavendiek, Udo"],["dc.contributor.author","Dieterich, Christoph"],["dc.contributor.author","Brors, Benedikt"],["dc.contributor.author","Kraus, Inga"],["dc.contributor.author","Thoms, Caroline"],["dc.contributor.author","Jäger, Dirk"],["dc.contributor.author","Ellenrieder, Volker"],["dc.contributor.author","Bergh, Björn"],["dc.contributor.author","Yahyapour, Ramin"],["dc.contributor.author","Eils, Roland"],["dc.contributor.author","Consortium, HiGHmed"],["dc.contributor.author","Marschollek, Michael"],["dc.date.accessioned","2020-12-10T18:47:27Z"],["dc.date.available","2020-12-10T18:47:27Z"],["dc.date.issued","2018"],["dc.description.abstract","This article is part of the Focus Theme of Methods of Information in Medicine on the German Medical Informatics Initiative. HiGHmed brings together 24 partners from academia and industry, aiming at improvements in care provision, biomedical research and epidemiology. By establishing a shared information governance framework, data integration centers and an open platform architecture in cooperation with independent healthcare providers, the meaningful reuse of data will be facilitated. Complementary, HiGHmed integrates a total of seven Medical Informatics curricula to develop collaborative structures and processes to train medical informatics professionals, physicians and researchers in new forms of data analytics."],["dc.identifier.doi","10.3414/ME18-02-0002"],["dc.identifier.eissn","2511-705X"],["dc.identifier.issn","0026-1270"],["dc.identifier.pmid","30016813"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15525"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78770"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.relation.eissn","2511-705X"],["dc.relation.issn","0026-1270"],["dc.relation.issn","2511-705X"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.title","HiGHmed – An Open Platform Approach to Enhance Care and Research across Institutional Boundaries"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2014Journal Article
    [["dc.bibliographiccitation.firstpage","926"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","American Journal of Infection Control"],["dc.bibliographiccitation.lastpage","928"],["dc.bibliographiccitation.volume","42"],["dc.contributor.author","Scheithauer, Simone"],["dc.contributor.author","Haefner, Helga"],["dc.contributor.author","Schroeder, Joerg"],["dc.contributor.author","Nowicki, Katharina"],["dc.contributor.author","Lemmen, Sebastian"],["dc.date.accessioned","2018-11-07T09:36:59Z"],["dc.date.available","2018-11-07T09:36:59Z"],["dc.date.issued","2014"],["dc.description.abstract","To assess the influence of signal colors on hand disinfectant dispenser activities, health care workers (HCWs) at a medical intensive care unit were analyzed for a total of 20 weeks with 8 weeks before and 12 weeks after exchange to signal color. No significant increase in hand rubs (HRs) per patient day (PD) was observed (about 40 HRs/PD); however, HCW-adjusted compliance showed a 6% increase with signal colored devices. Therefore, colored devices may help to improve hand hygiene compliance. Copyright (C) 2014 by the Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved."],["dc.description.sponsorship","Ophardt Hygienetechnik"],["dc.identifier.doi","10.1016/j.ajic.2014.05.021"],["dc.identifier.isi","000341306700024"],["dc.identifier.pmid","25087148"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32734"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Mosby-elsevier"],["dc.relation.issn","1527-3296"],["dc.relation.issn","0196-6553"],["dc.title","Influence of signal colored hand disinfectant dispensers on hand hygiene compliance at a medical intensive care unit"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2021Journal Article
    [["dc.bibliographiccitation.firstpage","3049"],["dc.bibliographiccitation.issue","14"],["dc.bibliographiccitation.journal","Journal of Clinical Medicine"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Gross, Oliver"],["dc.contributor.author","Moerer, Onnen"],["dc.contributor.author","Rauen, Thomas"],["dc.contributor.author","Böckhaus, Jan"],["dc.contributor.author","Hoxha, Elion"],["dc.contributor.author","Jörres, Achim"],["dc.contributor.author","Kamm, Matthias"],["dc.contributor.author","Elfanish, Amin"],["dc.contributor.author","Windisch, Wolfram"],["dc.contributor.author","Blaschke, Sabine"],["dc.contributor.author","Dreher, Michael"],["dc.contributor.author","Floege, Juergen"],["dc.contributor.author","Kluge, Stefan"],["dc.contributor.author","Schmidt-Lauber, Christian"],["dc.contributor.author","Turner, Jan-Eric"],["dc.contributor.author","Huber, Samuel"],["dc.contributor.author","Addo, Marylyn M."],["dc.contributor.author","Scheithauer, Simone"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Braun, Gerald S."],["dc.contributor.author","Huber, Tobias B."],["dc.date.accessioned","2021-08-12T07:46:00Z"],["dc.date.available","2021-08-12T07:46:00Z"],["dc.date.issued","2021"],["dc.description.abstract","In COVID-19, guidelines recommend a urinalysis on hospital admission as SARS-CoV-2 renal tropism, post-mortem, was associated with disease severity and mortality. Following the hypothesis from our pilot study, we now validate an algorithm harnessing urinalysis to predict the outcome and the need for ICU resources on admission to hospital. Patients were screened for urinalysis, serum albumin (SA) and antithrombin III activity (AT-III) obtained prospectively on admission. The risk for an unfavorable course was categorized as (1) “low”, (2) “intermediate” or (3) “high”, depending on (1) normal urinalysis, (2) abnormal urinalysis with SA ≥ 2 g/dL and AT-III ≥ 70%, or (3) abnormal urinalysis with SA or AT-III abnormality. Time to ICU admission or death served as the primary endpoint. Among 223 screened patients, 145 were eligible for enrollment, 43 falling into the low, 84 intermediate, and 18 into high-risk categories. An abnormal urinalysis significantly elevated the risk for ICU admission or death (63.7% vs. 27.9%; HR 2.6; 95%-CI 1.4 to 4.9; p = 0.0020) and was 100% in the high-risk group. Having an abnormal urinalysis was associated with mortality, a need for mechanical ventilation, extra-corporeal membrane oxygenation or renal replacement therapy. In conclusion, our data confirm that COVID-19-associated urine abnormalities on admission predict disease aggravation and the need for ICU (ClinicalTrials.gov number NCT04347824)."],["dc.description.abstract","In COVID-19, guidelines recommend a urinalysis on hospital admission as SARS-CoV-2 renal tropism, post-mortem, was associated with disease severity and mortality. Following the hypothesis from our pilot study, we now validate an algorithm harnessing urinalysis to predict the outcome and the need for ICU resources on admission to hospital. Patients were screened for urinalysis, serum albumin (SA) and antithrombin III activity (AT-III) obtained prospectively on admission. The risk for an unfavorable course was categorized as (1) “low”, (2) “intermediate” or (3) “high”, depending on (1) normal urinalysis, (2) abnormal urinalysis with SA ≥ 2 g/dL and AT-III ≥ 70%, or (3) abnormal urinalysis with SA or AT-III abnormality. Time to ICU admission or death served as the primary endpoint. Among 223 screened patients, 145 were eligible for enrollment, 43 falling into the low, 84 intermediate, and 18 into high-risk categories. An abnormal urinalysis significantly elevated the risk for ICU admission or death (63.7% vs. 27.9%; HR 2.6; 95%-CI 1.4 to 4.9; p = 0.0020) and was 100% in the high-risk group. Having an abnormal urinalysis was associated with mortality, a need for mechanical ventilation, extra-corporeal membrane oxygenation or renal replacement therapy. In conclusion, our data confirm that COVID-19-associated urine abnormalities on admission predict disease aggravation and the need for ICU (ClinicalTrials.gov number NCT04347824)."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft"],["dc.description.sponsorship","Bundesministerium für Bildung und Forschung"],["dc.identifier.doi","10.3390/jcm10143049"],["dc.identifier.pii","jcm10143049"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88595"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-448"],["dc.publisher","MDPI"],["dc.relation.eissn","2077-0383"],["dc.rights","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Validation of a Prospective Urinalysis-Based Prediction Model for ICU Resources and Outcome of COVID-19 Disease: A Multicenter Cohort Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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