Gliem, Nina

[["dc.bibliographiccitation.firstpage","861"],["dc.bibliographiccitation.issue","09"],["dc.bibliographiccitation.journal","Zeitschrift für Gastroenterologie"],["dc.bibliographiccitation.lastpage","865"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Gliem, Nina"],["dc.contributor.author","Broekaert, Sigrid"],["dc.contributor.author","Seitz, Cornelia"],["dc.contributor.author","Schön, Michael"],["dc.contributor.author","Ellenrieder, Volker"],["dc.date.accessioned","2020-12-10T18:12:26Z"],["dc.date.available","2020-12-10T18:12:26Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1055/s-0043-113833"],["dc.identifier.eissn","1439-7803"],["dc.identifier.issn","0044-2771"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74371"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Esomeprazol-induzierter kutaner Lupus erythematodes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","HNO"],["dc.contributor.author","Schuppe, Marie Charlotte"],["dc.contributor.author","Lex, Christiane"],["dc.contributor.author","Gliem, Nina"],["dc.contributor.author","Olgemüller, Ulrike"],["dc.contributor.author","Koziolek, Michael"],["dc.contributor.author","Forkel, Susann"],["dc.contributor.author","Gupta, Sidhi"],["dc.contributor.author","Dombrowski, Tobias"],["dc.contributor.author","Czech-Zechmeister, Bozena A."],["dc.contributor.author","Geier, Johannes"],["dc.contributor.author","Buhl, Timo"],["dc.date.accessioned","2022-11-01T10:17:33Z"],["dc.date.available","2022-11-01T10:17:33Z"],["dc.date.issued","2022"],["dc.description.abstract","Zusammenfassung\n \n Hintergrund\n Obwohl allergologische Erkrankungen zu den wichtigen Gesundheitsstörungen laut ärztlicher Approbationsordnung zählen, ist die Allergologie in Deutschland nicht als selbstständiges Fach im Studium der Humanmedizin verankert.\n \n \n Ziel der Arbeit\n Da sämtliche Universitäts- und Hochschulstandorte mit dieser Herausforderung umgehen müssen, war es Ziel unseres Lehrprojekts, eine exemplarische und mit allen beteiligten Kliniken und Instituten abgestimmte Koordination und Verzahnung der allergologischen Lehre an einem Standort zu etablieren. Insbesondere Comprehensive Allergy Centers (CAC) bieten eine bereits vorhandene Infrastruktur, in der diese Neukonzeption der allergologischen Lehre auf andere Standorte übertragen werden könnte.\n \n \n Material und Methoden\n Nach umfangreicher Bestandsaufnahme der aktuellen allergologischen Lehre an der Universitätsmedizin Göttingen wurde im interdisziplinären Konsens ein neues Lehrkonzept entwickelt, durch die Bereitstellung zusätzlicher digitaler Lehr- und Lernanteile ergänzt („blended learning“) und schließlich evaluiert.\n \n \n Ergebnisse\n Die allergologische Lehre im klinischen Studienabschnitt zeigte eine starke Fragmentierung, die ohne Koordination der zwölf beteiligten Kliniken/Institute und ohne Abstimmung der jeweiligen Lerninhalte stattfand. In der etablierten Struktur des interdisziplinären CAC erfolgte eine Neukonzeption, Koordination und Schwerpunktsetzung der studentischen Lehre zur klinischen Allergologie. Die Bereitstellung von neuen interaktiven Lerneinheiten sowie ergänzender Materialien zum Selbststudium wurden von den Studierenden positiv bewertet. Eine vergleichende Evaluation von Studierenden nach Absolvieren der unterschiedlichen Curricula zeigte signifikante Verbesserungen im Erreichen der gewünschten Lernziele."],["dc.description.abstract","Abstract\n \n Background\n Although allergic diseases are among the most important health disorders, allergology is not anchored as an independent subject in the clinical part of medical studies in Germany.\n \n \n Objective\n As all universities and institutes face the same challenge, the aim of our project was to establish exemplary coordination and networking of education in allergology at one location in agreement with all involved departments and institutes. Particularly, Comprehensive Allergy Centers (CAC) offer an established infrastructure via which the revised allergology education program can be transferred to other universities.\n \n \n Materials and methods\n After an extensive inventory of the current allergological curriculum at the University Medical Center Göttingen, a new teaching concept was developed in interdisciplinary consensus, supplemented by first-time provision of additional digital contents (“blended learning”), and finally evaluated.\n \n \n Results\n Initially, we observed a high level of fragmentation in the teaching of allergology in the clinical study sections of human medicine, with no coordination between the 12 clinical departments/institutes involved and no coherent framework for the specific learning content. Within the established structure of the interdisciplinary CAC, we revised, coordinated, and defined key areas for improved student education in clinical allergology. The allocation of new interactive learning elements as well as supplementary materials for self-studies was welcomed by the students and positively evaluated. A survey among students after completing the former vs. current curricula showed significant improvements in achieving the desired educational objectives."],["dc.identifier.doi","10.1007/s00106-022-01222-5"],["dc.identifier.pii","1222"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/116840"],["dc.language.iso","de"],["dc.notes.intern","DOI-Import GROB-605"],["dc.relation.eissn","1433-0458"],["dc.relation.issn","0017-6192"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Interdisziplinäre Neukonzeption der Lehre im Querschnittsfach „Allergologie“ im Studiengang Humanmedizin"],["dc.title.translated","New interdisciplinary teaching concept for the cross-sectional subject of allergology in human medicine studies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Japanese Journal of Radiology"],["dc.contributor.author","Biggemann, Lorenz"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Gliem, Nina"],["dc.contributor.author","Al-Bourini, Omar"],["dc.contributor.author","Wedi, Edris"],["dc.contributor.author","Ellenrieder, Volker"],["dc.contributor.author","Ghadimi, Michael"],["dc.contributor.author","Uecker, Martin"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Streit, Ulrike"],["dc.date.accessioned","2022-01-11T14:05:34Z"],["dc.date.available","2022-01-11T14:05:34Z"],["dc.date.issued","2021"],["dc.description.abstract","Abstract Purpose To assess the esophagogastric junction (EGJ) on real-time MRI and compare imaging parameters to EGJ morphology on high-resolution manometry (HRM). Methods A total of 105 of 117 eligible patients who underwent real-time MRI and high-resolution manometry for GERD-like symptoms between 2015 and 2018 at a single center were retrospectively evaluated (male n  = 57; female n  = 48; mean age 52.5 ± 15.4 years). Real-time MRI was performed at a median investigation time of 15 min (1 frame/40 ms). On HRM, EGJ morphology was assessed according to the Chicago classification of esophageal motility disorders. Real-time MRI was performed at 3 T using highly undersampled radial fast low-angle shot acquisitions with NLINV image reconstruction. A 10 mL pineapple juice bolus served as oral contrast agent at supine position. Real-time MRI films of the EGJ were acquired during swallowing events and during Valsalva maneuver. Anatomic and functional MRI parameters were compared to EGJ morphology on HRM. Results On HRM, n  = 42 patients presented with EGJ type I (40.0%), n  = 33 with EGJ type II (31.4%), and n  = 30 with EGJ type III (28.6%). On real-time MRI, hiatal hernia was more common in patients with EGJ type III (66.7%) than in patients with EGJ type I (26.2%) and EGJ type II (30.3%; p  < 0.001). Sliding hiatal hernia was more frequent in patients with EGJ type II (33.3%) than in patients with EGJ type III (16.7%) and EGJ type I (7.1%; p  = 0.017). The mean esophagus–fundus angle of patients was 85 ± 31° at rest and increased to 101 ± 36° during Valsalva maneuver. Conclusion Real-time MRI is a non-invasive imaging method for assessment of the esophagogastric junction. Real-time MRI can visualize dynamic changes of the EGJ during swallowing events."],["dc.identifier.doi","10.1007/s11604-021-01210-9"],["dc.identifier.pii","1210"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/97695"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-507"],["dc.relation.eissn","1867-108X"],["dc.relation.issn","1867-1071"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.relation.orgunit","Institut für Diagnostische und Interventionelle Neuroradiologie"],["dc.relation.orgunit","Max-Planck-Institut für biophysikalische Chemie"],["dc.title","Assessment of esophagogastric junction morphology by dynamic real-time MRI: comparison of imaging features to high-resolution manometry"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","703"],["dc.bibliographiccitation.issue","09"],["dc.bibliographiccitation.journal","Allergologie"],["dc.bibliographiccitation.lastpage","711"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Lex, C."],["dc.contributor.author","Beutner, D."],["dc.contributor.author","Buhl, T."],["dc.contributor.author","Czech-Zechmeister, B.A."],["dc.contributor.author","Dombrowski, T."],["dc.contributor.author","Ellenrieder, V."],["dc.contributor.author","Fischer, A."],["dc.contributor.author","Geier, J."],["dc.contributor.author","Gliem, N."],["dc.contributor.author","Hasenfuß, G."],["dc.contributor.author","Beutner, C."],["dc.date.accessioned","2022-12-01T08:31:49Z"],["dc.date.available","2022-12-01T08:31:49Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.5414/ALX02350"],["dc.identifier.pii","02350"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/118274"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-621"],["dc.relation.issn","0344-5062"],["dc.title","Allergiezentrum Südniedersachsen – Das Comprehensive Allergy Center der Universitätsmedizin Göttingen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","361"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Der Gastroenterologe"],["dc.bibliographiccitation.lastpage","365"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Gliem, N."],["dc.contributor.author","Ellenrieder, V."],["dc.date.accessioned","2020-12-10T14:12:00Z"],["dc.date.available","2020-12-10T14:12:00Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1007/s11377-018-0277-2"],["dc.identifier.eissn","1861-969X"],["dc.identifier.issn","1861-9681"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71271"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Seltene Formen der intestinalen Polyposis"],["dc.title.alternative","Rare forms of intestinal polyposis. Cronkhite–Canada syndrome and other hamartomatous polyposis syndromes"],["dc.title.subtitle","Cronkhite-Canada-Syndrom und andere hamartomatöse Polyposissyndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","108856"],["dc.bibliographiccitation.journal","European Journal of Radiology"],["dc.bibliographiccitation.volume","125"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Streit, Ulrike"],["dc.contributor.author","Gliem, Nina"],["dc.contributor.author","Wedi, Edris"],["dc.contributor.author","Ellenrieder, Volker"],["dc.contributor.author","Ghadimi, Michael B."],["dc.contributor.author","Ahmed, Saheeb"],["dc.contributor.author","Uecker, Martin"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Biggemann, Lorenz"],["dc.date.accessioned","2020-05-13T13:44:06Z"],["dc.date.available","2020-05-13T13:44:06Z"],["dc.date.issued","2020-04"],["dc.description.abstract","Purpose To evaluate the diagnostic potential of real-time MRI for dynamic assessment of gastroesophageal reflux in patients with GERD (gastroesophageal reflux disease)-like symptoms compared to pH-metry and impedance. Methods Patients who underwent real-time MRI and pH-metry between 2015–2018 were included in this retrospective study. Real-time MRI at 3 T was achieved by undersampled radial FLASH acquisitions with iterative image reconstruction by NLINV. Real-time MRI visualized transit of pineapple juice through the gastroesophageal junction and during Valsalva maneuver. MRI results were compared to 24 h pH-metry to assess acidic reflux (following Lyon Consensus guidelines) and to impedance to assess non-acidic reflux. A standard 2 × 2 table was chosen to calculate diagnostic performance. Results 91/93 eligible patients fulfilled inclusion criteria (male n = 49; female n = 42; median age 55 y). All MRI studies were successfully completed without adverse events at a mean examination time of 15 min. On real-time MRI, reflux was evident in 60 patients (66 %). pH-metry revealed reflux in 41 patients (45 %), and impedance in 54 patients (59 %). Compared to pH-metry and impedance, real-time MRI sensitivity was 0.78 (95 % CI: 0.66-0.87), specificity 0.67 (95 % CI: 0.45-0.84) and PPV 0.87 (95 % CI: 0.75-0.94). Conclusion Real-time MRI is an imaging method for assessment of gastroesophageal reflux in patients with GERD-like symptoms. Considering its high positive predictive value, real-time MRI can accurately identify patients in which further invasive testing with pH-metry and impedance might be considered."],["dc.identifier.doi","10.1016/j.ejrad.2020.108856"],["dc.identifier.pmid","32062571"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/65362"],["dc.language.iso","en"],["dc.relation.eissn","1872-7727"],["dc.relation.issn","0720-048X"],["dc.title","Real-time MRI for dynamic assessment of gastroesophageal reflux disease: Comparison to pH-metry and impedance"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","387"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Pflügers Archiv - European Journal of Physiology"],["dc.bibliographiccitation.lastpage","393"],["dc.bibliographiccitation.volume","446"],["dc.contributor.author","Schuttert, J. B."],["dc.contributor.author","Liu, M. H."],["dc.contributor.author","Gliem, N."],["dc.contributor.author","Fiedler, Gabriele"],["dc.contributor.author","Zopf, S."],["dc.contributor.author","Mayer, C."],["dc.contributor.author","Mueller, Gerhard A."],["dc.contributor.author","Grunewald, Rolf W."],["dc.date.accessioned","2018-11-07T10:38:45Z"],["dc.date.available","2018-11-07T10:38:45Z"],["dc.date.issued","2003"],["dc.description.abstract","Angiotensin II (Ang II) as a vasoactive hormone may be involved in progressive renal interstitial fibrosis. We investigated the influence of Ang II on cell proliferation and synthesis of extracellular matrix (collagen I, III and fibronectin) in human renal fibroblasts derived from normal (TK 173 cell line) and fibrotic (TK 188 cell line) kidneys which possess both Ang Il type I and type 2 (AT1 and AT2) receptors. Incubation of the cells with Ang II increased the cell proliferation and the synthesis of extracellular matrix significantly in both cell lines. However, proliferation and extracellular matrix synthesis showed a greater increase in the cells derived from the fibrotic kidney. The Ang II mediated effect on cell proliferation and extracellular matrix synthesis was diminished in the presence of the AT1 receptor blocker losartan in both cell lines. No inhibition was observed using the AT2 receptor blocker PD123319. Ang II induced cell proliferation could be completely inhibited by incubation with human TGF-betal antibody. Incubation with Ang II did not affect TGF beta 1 production but in untreated cells TGF-beta 1 content was higher in the cells derived from the fibrotic kidney. This might be the reason for the more sensitive reaction on exposure to Ang II."],["dc.identifier.doi","10.1007/s00424-003-1026-y"],["dc.identifier.isi","000184055800016"],["dc.identifier.pmid","12684791"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/45886"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.conference","3rd FEPS Meeting"],["dc.relation.eventlocation","NICE, FRANCE"],["dc.relation.issn","0031-6768"],["dc.title","Human renal fibroblasts derived from normal and fibrotic kidneys show differences in increase of extracellular matrix synthesis and cell proliferation upon angiotensin II exposure"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.journal","Digestion"],["dc.bibliographiccitation.lastpage","5"],["dc.contributor.author","Gliem, Nina"],["dc.contributor.author","Ammer-Herrmenau, Christoph"],["dc.contributor.author","Ellenrieder, Volker"],["dc.contributor.author","Neesse, Albrecht"],["dc.date.accessioned","2021-06-01T10:47:46Z"],["dc.date.available","2021-06-01T10:47:46Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1159/000506830"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85714"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1421-9867"],["dc.relation.issn","0012-2823"],["dc.title","Management of Severe Acute Pancreatitis: An Update"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","109265"],["dc.bibliographiccitation.journal","European Journal of Radiology"],["dc.bibliographiccitation.volume","132"],["dc.contributor.author","Biggemann, Lorenz"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Gliem, Nina"],["dc.contributor.author","Al-Bourini, Omar"],["dc.contributor.author","Wedi, Edris"],["dc.contributor.author","Ellenrieder, Volker"],["dc.contributor.author","Ghadimi, Michael B."],["dc.contributor.author","Uecker, Martin"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Hosseini, Ali Seif Amir"],["dc.contributor.author","Streit, Ulrike"],["dc.date.accessioned","2021-03-08T07:14:06Z"],["dc.date.available","2021-03-08T07:14:06Z"],["dc.date.issued","2020-11"],["dc.description.abstract","To investigate imaging findings of esophageal motility disorders on dynamic real-time."],["dc.identifier.doi","10.1016/j.ejrad.2020.109265"],["dc.identifier.pmid","33010683"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80478"],["dc.language.iso","en"],["dc.relation.eissn","1872-7727"],["dc.relation.issn","0720-048X"],["dc.title","Assessment of esophageal motility disorders by real-time MRI"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]