Now showing 1 - 4 of 4
  • 2019Journal Article
    [["dc.bibliographiccitation.firstpage","e17082"],["dc.bibliographiccitation.issue","37"],["dc.bibliographiccitation.journal","Medicine"],["dc.bibliographiccitation.volume","98"],["dc.contributor.author","Wienbeck, Susanne"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Fischer, Uwe"],["dc.contributor.author","Hellriegel, Martin"],["dc.contributor.author","von Fintel, Eva"],["dc.contributor.author","Kulenkampff, Dietrich"],["dc.contributor.author","Surov, Alexey"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Perske, Christina"],["dc.date.accessioned","2020-12-10T18:20:08Z"],["dc.date.available","2020-12-10T18:20:08Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1097/MD.0000000000017082"],["dc.identifier.issn","0025-7974"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16517"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75461"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY-NC-ND 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc-nd/4.0"],["dc.title","Breast lesion size assessment in mastectomy specimens"],["dc.title.alternative","Correlation of cone-beam breast-CT, digital breast tomosynthesis and full-field digital mammography with histopathology"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2016Journal Article
    [["dc.bibliographiccitation.firstpage","2132"],["dc.bibliographiccitation.issue","20"],["dc.bibliographiccitation.journal","Neurology"],["dc.bibliographiccitation.lastpage","2138"],["dc.bibliographiccitation.volume","87"],["dc.contributor.author","Olthoff, Arno"],["dc.contributor.author","Carstens, Per-Ole"],["dc.contributor.author","Zhang, Shuo"],["dc.contributor.author","von Fintel, Eva"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Schmidt, Jens"],["dc.date.accessioned","2020-12-10T18:41:43Z"],["dc.date.available","2020-12-10T18:41:43Z"],["dc.date.issued","2016"],["dc.description.abstract","Objective: To assess safety and feasibility of real-time (RT) MRI for evaluation of dysphagia and to compare this technique to standard assessment by flexible endoscopic evaluation of swallowing (FEES) and videofluoroscopy (VF) in a cohort of patients with inclusion body myositis (IBM). Methods: Using RT-MRI, FEES, and VF, an unselected cohort of 20 patients with IBM was studied as index disease with a uniform dysphagia. Symptoms of IBM and dysphagia were explored by standardized tools including Swallowing-Related Quality of Life Questionnaire (SWAL-QoL), IBM Functional Rating Scale, Patient-Reported Functional Assessment, and Medical Research Council Scale. Results: Dysphagia was noted in 80% of the patients and SWAL-QoL was impaired in patients with IBM compared to published reference values of healthy elderly. Swallowing in a supine position during RT-MRI was well-tolerated by all patients. RT-MRI equally revealed dysphagia compared to VF and FEES and correlated well with the SWAL-QoL. Only RT-MRI allowed precise time measurements and identification of the respective tissue morphology. The pharyngeal transit times were 2-fold longer compared to published reference values and significantly correlated with morphologic abnormalities. Conclusions: RT-MRI is safe and equally capable as VF to identify the cause of dysphagia in IBM. Advantages of RT-MRI include visualization of soft tissue, more reliable timing analysis, and lack of X-ray exposure. RT-MRI may become a routine diagnostic tool for detailed assessment of the esophagus and other moving parts of the body, facilitating longitudinal evaluations in daily practice and clinical trials."],["dc.identifier.doi","10.1212/WNL.0000000000003337"],["dc.identifier.eissn","1526-632X"],["dc.identifier.isi","000392236100014"],["dc.identifier.issn","0028-3878"],["dc.identifier.pmid","27770070"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77659"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1526-632X"],["dc.relation.issn","0028-3878"],["dc.title","Evaluation of dysphagia by novel real-time MRI"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]
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  • 2017-12Journal Article
    [["dc.bibliographiccitation.firstpage","904"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Translational oncology"],["dc.bibliographiccitation.lastpage","910"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Fischer, Uwe"],["dc.contributor.author","von Fintel, Eva"],["dc.contributor.author","Stahnke, Vera"],["dc.contributor.author","Perske, Christina"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Wienbeck, Susanne"],["dc.date.accessioned","2019-07-09T11:44:45Z"],["dc.date.available","2019-07-09T11:44:45Z"],["dc.date.issued","2017-12"],["dc.description.abstract","PURPOSE: To evaluate whether contrast enhancement on cone-beam breast-CT (CBBCT) could aid in discrimination of breast cancer subtypes and receptor status. METHODS: This study included female patients age >40 years with malignant breast lesions identified on contrast-enhanced CBBCT. Contrast enhancement of malignant breast lesions was standardized to breast fat tissue contrast enhancement. All breast lesions were approved via image-guided biopsy or surgery. Immunohistochemical staining was conducted for expression of estrogen (ER), progesterone (PR), human epidermal growth factor receptor-2 (HER2) and Ki-67 index. Contrast enhancement of breast lesions was correlated with immunohistochemical breast cancer subtypes (Luminal A, Luminal B, HER2 positive, triple negative), receptor status and Ki-67 expression. RESULTS: Highest contrast enhancement was seen for Luminal A lesions (93.6 HU) compared to Luminal B lesions (47.6 HU, P=.002), HER2 positive lesions (83.5 HU, P=.359) and triple negative lesions (45.3 HU, P=.005). Contrast enhancement of HER2 positive lesions was higher than Luminal B lesions (P=.044) and triple negative lesions (P=.039). No significant difference was evident between Luminal B and triple negative lesions (P=.439). Lesions with high Ki-67 index showed lower contrast enhancement than those with low Ki-67 index (P=.0043). ER, PR and HER2 positive lesions demonstrated higher contrast enhancement than their receptor negative counterparts, although differences did not reach statistical significance (P=.1714; P=.3603; P=.2166). CONCLUSIONS: Contrast enhancement of malignant breast lesions on CBBCT correlates with immunohistochemical subtype and proliferative potential. Thereby, CBBCT might aid in selecting individualized treatment strategies for breast cancer patients based on pre-operative imaging."],["dc.identifier.doi","10.1016/j.tranon.2017.08.010"],["dc.identifier.pmid","28946110"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/14887"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59085"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1936-5233"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.subject.ddc","610"],["dc.title","Contrast Enhancement on Cone-Beam Breast-CT for Discrimination of Breast Cancer Immunohistochemical Subtypes."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]
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  • 2017Journal Article
    [["dc.bibliographiccitation.firstpage","5185"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","European Radiology"],["dc.bibliographiccitation.lastpage","5195"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Wienbeck, Susanne"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Luftner-Nagel, Susanne"],["dc.contributor.author","Zapf, Antonia"],["dc.contributor.author","Surov, Alexey"],["dc.contributor.author","von Fintel, Eva"],["dc.contributor.author","Stahnke, Vera"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Fischer, Uwe"],["dc.date.accessioned","2020-12-10T14:10:11Z"],["dc.date.available","2020-12-10T14:10:11Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00330-017-4911-z"],["dc.identifier.eissn","1432-1084"],["dc.identifier.issn","0938-7994"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70670"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","The role of cone-beam breast-CT for breast cancer detection relative to breast density"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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