Schneider, Lukas

[["dc.bibliographiccitation.firstpage","463"],["dc.bibliographiccitation.journal","Computer Physics Communications"],["dc.bibliographiccitation.lastpage","476"],["dc.bibliographiccitation.volume","235"],["dc.contributor.author","Schneider, L."],["dc.contributor.author","Müller, M."],["dc.date.accessioned","2020-12-10T14:23:18Z"],["dc.date.available","2020-12-10T14:23:18Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.cpc.2018.08.011"],["dc.identifier.issn","0010-4655"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71894"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Multi-architecture Monte-Carlo (MC) simulation of soft coarse-grained polymeric materials: SOft coarse grained Monte-Carlo Acceleration (SOMA)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","135"],["dc.bibliographiccitation.journal","Cortex"],["dc.bibliographiccitation.lastpage","149"],["dc.bibliographiccitation.volume","99"],["dc.contributor.author","Wilke, Melanie"],["dc.contributor.author","Schneider, Lukas"],["dc.contributor.author","Dominguez-Vargas, Adan-Ulises"],["dc.contributor.author","Schmidt-Samoa, Carsten"],["dc.contributor.author","Miloserdov, Kristina"],["dc.contributor.author","Nazzal, Ahmad"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Cabral-Calderin, Yuranny"],["dc.contributor.author","Scherberger, Hansjörg"],["dc.contributor.author","Kagan, Igor"],["dc.contributor.author","Bähr, Mathias"],["dc.date.accessioned","2018-02-08T10:49:56Z"],["dc.date.available","2018-02-08T10:49:56Z"],["dc.date.issued","2018-02"],["dc.description.abstract","Expansion of the dorsal pulvinar in humans and its anatomical connectivity suggests its involvement in higher-order cognitive and visuomotor functions. We investigated visuomotor performance in a 31 year old patient (M.B.) with a lesion centered on the medial portion of the dorsal pulvinar (left > right) due to an atypical Sarcoidosis manifestation. Unlike lesions with a vascular etiology, the lesion of M.B. did not include primary sensory or motor thalamic nuclei. Thus, this patient gave us the exceedingly rare opportunity to study the contribution of the dorsal pulvinar to visuomotor behavior in a human without confounding losses in primary sensory or motor domains. We investigated reaching, saccade and visual decision making performance. Patient data in each task was compared to at least seven age matched healthy controls. While saccades were hypometric towards both hemifields, the patient did not show any spatial choice bias or perceptual deficits. At the same time, he exhibited reach and grasp difficulties, which shared features with both, parietal and cerebellar damage. In particular, he had problems to form a precision grip and exhibited reach deficits expressed in decreased accuracy, delayed initiation and prolonged movement durations. Reach deficits were similar in foveal and extrafoveal viewing conditions and in both visual hemifields but were stronger with the right hand. These results suggest that dorsal pulvinar function in humans goes beyond its subscribed role in visual cognition and is critical for the programming of voluntary actions with the hands."],["dc.identifier.doi","10.1016/j.cortex.2017.10.011"],["dc.identifier.pmid","29216478"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/12057"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.doi","10.1016/j.cortex.2017.10.011"],["dc.relation.eissn","1973-8102"],["dc.relation.issn","1973-8102"],["dc.title","Reach and grasp deficits following damage to the dorsal pulvinar"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","367"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Neurophysiology"],["dc.bibliographiccitation.lastpage","391"],["dc.bibliographiccitation.volume","123"],["dc.contributor.author","Schneider, Lukas"],["dc.contributor.author","Dominguez-Vargas, Adan-Ulises"],["dc.contributor.author","Gibson, Lydia"],["dc.contributor.author","Kagan, Igor"],["dc.contributor.author","Wilke, Melanie"],["dc.date.accessioned","2020-12-10T18:37:39Z"],["dc.date.available","2020-12-10T18:37:39Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1152/jn.00432.2019"],["dc.identifier.eissn","1522-1598"],["dc.identifier.issn","0022-3077"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77054"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Eye position signals in the dorsal pulvinar during fixation and goal-directed saccades"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2234"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","The Journal of Neuroscience"],["dc.bibliographiccitation.lastpage","2257"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Dominguez-Vargas, Adan-Ulises"],["dc.contributor.author","Schneider, Lukas"],["dc.contributor.author","Wilke, Melanie"],["dc.contributor.author","Kagan, Igor"],["dc.date.accessioned","2021-06-01T10:48:23Z"],["dc.date.available","2021-06-01T10:48:23Z"],["dc.date.issued","2017"],["dc.description.abstract","The pulvinar complex is interconnected extensively with brain regions involved in spatial processing and eye movement control. Recent inactivation studies have shown that the dorsal pulvinar (dPul) plays a role in saccade target selection; however, it remains unknown whether it exerts effects on visual processing or at planning/execution stages. We used electrical microstimulation of the dPul while monkeys performed saccade tasks toward instructed and freely chosen targets. Timing of stimulation was varied, starting before, at, or after onset of target(s). Stimulation affected saccade properties and target selection in a time-dependent manner. Stimulation starting before but overlapping with target onset shortened saccadic reaction times (RTs) for ipsiversive (to the stimulation site) target locations, whereas stimulation starting at and after target onset caused systematic delays for both ipsiversive and contraversive locations. Similarly, stimulation starting before the onset of bilateral targets increased ipsiversive target choices, whereas stimulation after target onset increased contraversive choices. Properties of dPul neurons and stimulation effects were consistent with an overall contraversive drive, with varying outcomes contingent upon behavioral demands. RT and choice effects were largely congruent in the visually-guided task, but stimulation during memory-guided saccades, while influencing RTs and errors, did not affect choice behavior. Together, these results show that the dPul plays a primary role in action planning as opposed to visual processing, that it exerts its strongest influence on spatial choices when decision and action are temporally close, and that this choice effect can be dissociated from motor effects on saccade initiation and execution."],["dc.identifier.doi","10.1523/JNEUROSCI.1984-16.2016"],["dc.identifier.gro","3151616"],["dc.identifier.pmid","28119401"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85917"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","final"],["dc.notes.submitter","chake"],["dc.relation.eissn","1529-2401"],["dc.relation.issn","0270-6474"],["dc.title","Electrical Microstimulation of the Pulvinar Biases Saccade Choices and Reaction Times in a Time-Dependent Manner"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Schneider, Lukas"],["dc.contributor.author","Dominguez-Vargas, Adan-Ulises"],["dc.contributor.author","Gibson, Lydia"],["dc.contributor.author","Kagan, Igor"],["dc.contributor.author","Wilke, Melanie"],["dc.date.accessioned","2019-07-30T07:42:00Z"],["dc.date.available","2019-07-30T07:42:00Z"],["dc.date.issued","2019"],["dc.description.abstract","Most sensorimotor cortical areas contain eye position information thought to ensure perceptual stability across saccades and underlie spatial transformations supporting goal-directed actions. One pathway by which eye position signals could be relayed to and across cortical areas is via the dorsal pulvinar. Several studies demonstrated saccade-related activity in the dorsal pulvinar and we have recently shown that many neurons exhibit post-saccadic spatial preference long after the saccade execution. In addition, dorsal pulvinar lesions lead to gaze-holding deficits expressed as nystagmus or ipsilesional gaze bias, prompting us to investigate the effects of eye position. We tested three starting eye positions (-15°/0°/15°) in monkeys performing a visually-cued memory saccade task. We found two main types of gaze dependence. First, ~50% of neurons showed an effect of static gaze direction during initial and post-saccadic fixation. Eccentric gaze preference was more common than straight ahead. Some of these neurons were not visually-responsive and might be primarily signaling the position of the eyes in the orbit, or coding foveal targets in a head/body/world-centered reference frame. Second, many neurons showed a combination of eye-centered and gaze-dependent modulation of visual, memory and saccadic responses to a peripheral target. A small subset showed effects consistent with eye position-dependent gain modulation. Analysis of reference frames across task epochs from visual cue to post-saccadic target fixation indicated a transition from predominantly eye-centered encoding to representation of final gaze or foveated locations in non-retinocentric coordinates. These results show that dorsal pulvinar neurons carry information about eye position, which could contribute to steady gaze during postural changes and to reference frame transformations for visually-guided eye and limb movements."],["dc.identifier.doi","10.1101/681130"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62175"],["dc.language.iso","en"],["dc.title","Eye position signals in the dorsal pulvinar during fixation and goal-directed saccades"],["dc.type","preprint"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]