Suhr, Markus

[["dc.contributor.author","Umbach, Nadine"],["dc.contributor.author","Freckmann, Luca"],["dc.contributor.author","Knopp, Cornelius"],["dc.contributor.author","Meyer, Tim"],["dc.contributor.author","Suhr, Markus"],["dc.contributor.author","Kusch, Harald"],["dc.creator.author","Harald Kusch"],["dc.creator.author","Tim Meyer"],["dc.creator.author","Nadine Umbach"],["dc.creator.author","Luca Freckmann"],["dc.creator.author","Cornelius Knopp"],["dc.creator.author","Markus Suhr"],["dc.date.accessioned","2019-10-16T07:34:34Z"],["dc.date.available","2019-10-16T07:34:34Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.3205/18gmds098"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62499"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/224"],["dc.language.iso","en"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.conference","63. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS)"],["dc.relation.eventend","2018"],["dc.relation.eventlocation","Osnabrück"],["dc.relation.eventstart","2018"],["dc.relation.workinggroup","RG Nußbeck"],["dc.relation.workinggroup","RG Zimmermann (Engineered Human Myocardium)"],["dc.title","From seamless acquisition and sustainable management to publication of next-generation sequencing data"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","363"],["dc.bibliographiccitation.lastpage","367"],["dc.contributor.author","Suhr, Markus"],["dc.contributor.author","Umbach, Nadine"],["dc.contributor.author","Meyer, Tim"],["dc.contributor.author","Zimmermann, Wolfram-Hubertus"],["dc.contributor.author","Sax, Ulrich"],["dc.contributor.editor","Ohno-Machado, Lucila"],["dc.contributor.editor","Séroussi, Brigitte"],["dc.date.accessioned","2022-05-13T08:13:00Z"],["dc.date.available","2022-05-13T08:13:00Z"],["dc.date.issued","2019-08-21"],["dc.description.abstract","Methods for cardiac tissue engineering and application in experiments are core technologies developed at the Institute of Pharmacology and Toxicology in Göttingen. As is the case in many academic research laboratories data capture and documentation may be improved to latest methods of digital research. A comprehensive information system infrastructure is the foundation of further advances toward automation of lab processes. A data management system concept is proposed and prototypically deployed that enables traceability of assets within the lab and reproducibility of published assays and results. The prototype integrates existing electronic lab notebook, experiment result database, and a newly introduced research data management system by means of a custom developed portal and integration component. The architecture concept and developed integration tools explore connection of routine experimental work in a biomedical research lab to a universal infrastructure of data."],["dc.identifier.doi","10.3233/SHTI190244"],["dc.identifier.pmid","31437946"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107853"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/306"],["dc.language.iso","en"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.ispartof","MEDINFO 2019: Health and Wellbeing e-Networks for All"],["dc.relation.workinggroup","RG Nußbeck"],["dc.relation.workinggroup","RG Zimmermann (Engineered Human Myocardium)"],["dc.title","Cardiac Tissue Engineering as Use Case to Connect Biomedical Research Laboratories to an Emerging Global Data Infrastructure"],["dc.type","book_chapter"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Suhr, Markus"],["dc.contributor.author","Jahn, Najko"],["dc.contributor.author","Mietchen, Daniel"],["dc.contributor.author","Kusch, Harald"],["dc.creator.author","Najko Jahn"],["dc.creator.author","Daniel Mietchen"],["dc.creator.author","Markus Suhr"],["dc.creator.author","Harald Kusch"],["dc.date.accessioned","2019-10-16T07:37:33Z"],["dc.date.available","2019-10-16T07:37:33Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.3205/18gmds173"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62500"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/222"],["dc.language.iso","en"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.conference","63. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e. V. (GMDS)"],["dc.relation.eventend","2018"],["dc.relation.eventlocation","Osnabrück"],["dc.relation.eventstart","2018"],["dc.relation.workinggroup","RG Nußbeck"],["dc.title","Wikidata as semantic representation platform of the scientific achievements of the biomedical Collaborative Research Centre 1002"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","GMS German Medical Science"],["dc.contributor.author","Lehmann, Christoph"],["dc.contributor.author","Suhr, Markus"],["dc.contributor.author","Umbach, Nadine"],["dc.contributor.author","Cyganek, Lukas"],["dc.contributor.author","Kleinsorge, Mandy"],["dc.contributor.author","Nussbeck, Sara Yasemin"],["dc.contributor.author","Kusch, Harald"],["dc.date.accessioned","2022-05-17T08:04:37Z"],["dc.date.available","2022-05-17T08:04:37Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.3205/19gmds037"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107988"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/346"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.conference","64. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)"],["dc.relation.eventend","2019-09-11"],["dc.relation.eventlocation","Dortmund"],["dc.relation.eventstart","2019-09-08"],["dc.relation.workinggroup","RG Cyganek (Stem Cell Unit)"],["dc.relation.workinggroup","RG Nußbeck"],["dc.title","Leaving spreadsheets behind – FAIR documentation and representation of human stem cell lines in the Collaborative Research Centre 1002 Meeting Abstract"],["dc.type","conference_abstract"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","GMS German Medical Science"],["dc.contributor.author","Bender, Theresa"],["dc.contributor.author","Parciak, Marcel"],["dc.contributor.author","Suhr, Markus"],["dc.contributor.author","Sax, Ulrich"],["dc.contributor.author","Bauer, Christian R."],["dc.date.accessioned","2022-05-17T08:04:51Z"],["dc.date.available","2022-05-17T08:04:51Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.3205/20gmds162"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107990"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/389"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.conference","65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)"],["dc.relation.eventend","2020-09-09"],["dc.relation.eventlocation","Berlin"],["dc.relation.eventstart","2020-09-06"],["dc.relation.workinggroup","RG Nußbeck"],["dc.title","Sustainable Deployment of Research Infrastructure Components"],["dc.type","conference_abstract"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Suhr, Markus"],["dc.contributor.author","Lehmann, Christoph"],["dc.contributor.author","Bauer, Christian Robert"],["dc.contributor.author","Bender, Theresa"],["dc.contributor.author","Knopp, Cornelius"],["dc.contributor.author","Freckmann, Luca"],["dc.contributor.author","Hansen, Björn Öst"],["dc.contributor.author","Henke, Christian"],["dc.contributor.author","Aschenbrandt, Georg"],["dc.contributor.author","Kühlborn, Lea Katharina"],["dc.contributor.author","Rheinländer, Sophia"],["dc.contributor.author","Weber, Linus"],["dc.contributor.author","Marzec, Bartlomiej"],["dc.contributor.author","Hellkamp, Marcel"],["dc.contributor.author","Wieder, Philipp"],["dc.contributor.author","Kusch, Harald"],["dc.contributor.author","Sax, Ulrich"],["dc.contributor.author","Nussbeck, Sara Yasemin"],["dc.date.accessioned","2020-03-30T08:51:14Z"],["dc.date.available","2020-03-30T08:51:14Z"],["dc.date.issued","2020-02-07"],["dc.description.abstract","Background: Biomedical research projects deal with data management requirements from multiple sources like funding agencies' guidelines, publisher policies, discipline best practices, and their own users' needs. We describe functional and quality requirements based on many years of experience implementing data management for the CRC 1002 and CRC 1190. A fully equipped data management software should improve documentation of experiments and materials, enable data storage and sharing according to the FAIR Guiding Principles while maximizing usability, information security, as well as software sustainability and reusability. Results: We introduce the modular web portal software menoci for data collection, experiment documentation, data publication, sharing, and preservation in biomedical research projects. Menoci modules are based on the Drupal content management system which enables lightweight deployment and setup, and creates the possibility to combine research data management with a customisable project home page or collaboration platform. Conclusions: Management of research data and digital research artefacts is transforming from individual researcher or groups best practices towards project- or organisation-wide service infrastructures. To enable and support this structural transformation process, a vital ecosystem of open source software tools is needed. Menoci is a contribution to this ecosystem of research data management tools that is specifically designed to support biomedical research projects."],["dc.identifier.arxiv","2002.06161"],["dc.identifier.doi","10.48550/arXiv.2002.06161"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/63412"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/342"],["dc.identifier.url","https://sfb1190.med.uni-goettingen.de/production/literature/publications/106"],["dc.language.iso","en"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation","SFB 1190: Transportmaschinen und Kontaktstellen zellulärer Kompartimente"],["dc.relation","SFB 1190 | Z03: Synthetische genetische Analyse, automatisierte Mikroskopie und Bildanalyse"],["dc.relation.workinggroup","RG Nußbeck"],["dc.relation.workinggroup","RG Schwappach (Membrane Protein Biogenesis)"],["dc.title","menoci: Lightweight Extensible Web Portal enabling FAIR Data Management for Biomedical Research Projects"],["dc.type","preprint"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.contributor.advisorcorporation","Georg-August-Universität Göttingen"],["dc.contributor.author","Suhr, Markus"],["dc.date.accessioned","2019-11-26T08:55:32Z"],["dc.date.available","2019-11-26T08:55:32Z"],["dc.date.issued","2018"],["dc.description.abstract","Methods for the generation of engineered heart muscle (EHM) from induced pluripotent stem cells and application in experiment are advanced at the Institute of Pharmacology and Toxicology in Göttingen. Documentation and data capture do not adhere to latest developments of digital research. A comprehensive information system infrastructure is the foundation of further advances toward automation of lab processes. A data management system concept is proposed, prototypically deployed, and evaluated that should enable traceability of assets within the lab and reproducibility of published assays and results. Challenges, approaches, and software solutions are investigated by literature search and assessment. System requirements are defined based on regulations, best practises, and analysis of the local processes. Overarching goals are to enable research process, to maximize usability, to ensure information security, to favour dynamic extension, to maximize sustainability, and to increase reporting quality of results. These are translated into an architecture framework for a comprehensive research laboratory data management system. The proposed framework uses a service integration approach to combine five core components into a central portal site: electronic laboratory notebook, laboratory information management system, data integration and analysis system, research data management system, and multiple experiment-specific systems. Practical application of the concept is demonstrated by implementing a prototype system. The prototype integrates an existing electronic lab notebook, existing EHM process database, and a newly introduced research data management system by means of a custom developed portal and integration component based on the Drupal framework. Evaluation of the deployed prototype’s contribution to process quality shows moderately positive results. The overall architecture and developed tools are promising foundation for subsequent advancements."],["dc.format.extent","121"],["dc.identifier.issn","1612-6793"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62671"],["dc.language.iso","en"],["dc.publisher.place","Göttingen"],["dc.title","Concept for acquisition and storage of process data and metadata to improve traceability and reproducibility in biomedicine"],["dc.type","thesis"],["dc.type.internalPublication","yes"],["dc.type.subtype","master"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","GMS German Medical Science"],["dc.contributor.author","Rheinländer, Sophia"],["dc.contributor.author","Aschenbrandt, Georg"],["dc.contributor.author","Nussbeck, Sara Yasemin"],["dc.contributor.author","Suhr, Markus"],["dc.contributor.author","Kusch, Harald"],["dc.date.accessioned","2022-05-17T08:04:44Z"],["dc.date.available","2022-05-17T08:04:44Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.3205/19gmds038"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/107989"],["dc.identifier.url","https://sfb1002.med.uni-goettingen.de/production/literature/publications/347"],["dc.relation","SFB 1002: Modulatorische Einheiten bei Herzinsuffizienz"],["dc.relation","SFB 1002 | INF: Unterstützung der SFB 1002 Forschungsdatenintegration, -visualisierung und -nachnutzung"],["dc.relation.conference","64. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)"],["dc.relation.eventend","2019-09-11"],["dc.relation.eventlocation","Dortmund"],["dc.relation.eventstart","2019-09-08"],["dc.relation.workinggroup","RG Nußbeck"],["dc.title","Towards standardized documentation of mouse lines in biomedical basic research"],["dc.type","conference_abstract"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]