Emmert, Steffen

[["dc.bibliographiccitation.firstpage","278"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Plasma Processes and Polymers"],["dc.bibliographiccitation.lastpage","286"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Helmke, Andreas"],["dc.contributor.author","Hoffmeister, Dennis"],["dc.contributor.author","Berge, Frank"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Laspe, Petra"],["dc.contributor.author","Mertens, Nina"],["dc.contributor.author","Vioel, Wolfgang"],["dc.contributor.author","Weltmann, Klaus-Dieter"],["dc.date.accessioned","2018-11-07T08:56:58Z"],["dc.date.available","2018-11-07T08:56:58Z"],["dc.date.issued","2011"],["dc.description.abstract","The inactivation of the Gram-positive bacteria Staphylococcus epidermidis (ATCC 12228) in its vegetative state was studied in vitro after exposure to cold atmospheric pressure plasma generated by direct dielectric barrier discharge (DBD). Compared to UV radiation at 254 nm, plasma UV emission yielded no significant contribution to bacterial inactivation. Analysis of bacterial growth inhibition revealed a pH dependency on growth media. Yet, measurements combined with numerical simulations excluded the pH shift induced by plasma generated reactive species as the main cause of bacterial inactivation. Scanning electron microscopy (SEM) images showed no alteration of cell walls, while fluorescence microscopy revealed lethal damage to cell membranes even after 1 s treatment. When the cell membrane was already severely damaged, also degradation of the bacterial DNA by plasma treatment was found. We conclude that membrane damage due to reactive oxygen species (ROS) and DNA degradation are the main mechanisms of plasma-induced bacterial death that is aggregated by milieu acidification."],["dc.identifier.doi","10.1002/ppap.201000168"],["dc.identifier.isi","000289999200001"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23275"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-v C H Verlag Gmbh"],["dc.relation.issn","1612-8869"],["dc.relation.issn","1612-8850"],["dc.title","Physical and Microbiological Characterisation of Staphylococcus epidermidis Inactivation by Dielectric Barrier Discharge Plasma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1085"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Carcinogenesis"],["dc.bibliographiccitation.lastpage","1090"],["dc.bibliographiccitation.volume","26"],["dc.contributor.author","Blankenburg, S."],["dc.contributor.author","Konig, I. R."],["dc.contributor.author","Moessner, R."],["dc.contributor.author","Laspe, Petra"],["dc.contributor.author","Thoms, Kai Martin"],["dc.contributor.author","Krueger, Ulrich"],["dc.contributor.author","Khan, Sajjad"],["dc.contributor.author","Westphal, G."],["dc.contributor.author","Berking, Carola"],["dc.contributor.author","Volkenandt, Matthias"],["dc.contributor.author","Reich, Kristian"],["dc.contributor.author","Neumann, C."],["dc.contributor.author","Ziegler, Andreas"],["dc.contributor.author","Kraemer, Kenneth H."],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T10:29:15Z"],["dc.date.available","2018-11-07T10:29:15Z"],["dc.date.issued","2005"],["dc.description.abstract","Individuals with the rare DNA repair deficiency syndrome xeroderma pigmentosum (XP) are sensitive to the sun and exhibit a 1000-fold increased risk for developing skin cancers, including cutaneous melanoma. Inherited polymorphisms of XP genes may contribute to subtle variations in DNA repair capacity and genetic susceptibility to melanoma. We investigated the role of three polymorphic alleles of the DNA repair gene XPC in a hospital-based case-control study of 294 Caucasian patients from Germany who had cutaneous melanoma and 375 healthy cancer-free sex-matched Caucasian control subjects from the same area. We confirmed that the XPC intron 9 PAT+, intron 11 -6A, and the exon 15 2920C polymorphisms are in a linkage disequilibrium. Only 1.6% of the 669 donors genotyped were discordant for these three polymorphisms. The allele frequencies (cases: controls) were for intron 9 PAT+ 41.7%:36.9%, for intron 11 -6A 41.8%:37.0% and for exon 15 2920C 41.3%:37.3%. Using multivariate logistic regression analyses to control for age, skin type and number of nevi, the three polymorphisms were significantly associated with increased risks of melanoma: OR 1.87 (95% CI: 1.10-3.19; P = 0.022), OR 1.83 (95% CI: 1.07-3.11; P = 0.026), and OR 1.82 (95% CI: 1.07-3.08; P = 0.026), respectively. Exploratory multivariate analyses of distinct subgroups revealed that these polymorphisms were associated with increased risks for the development of multiple primary melanomas (n = 28). The results of our case-control study support the hypothesis that the intron 9 PAT+, intron 11 -6A and exon 15 2920C haplotype may contribute to the risk of developing cutaneous melanoma by increasing the rate of an alternatively spliced XPC mRNA isoform that skips exon 12 and leads to reduced DNA repair. Our results should be validated in independent samples in order to guard against false positive findings."],["dc.description.sponsorship","Intramural NIH HHS [Z01 BC004517-31]"],["dc.identifier.doi","10.1093/carcin/bgi055"],["dc.identifier.isi","000229700100008"],["dc.identifier.pmid","15731165"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/43601"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","0143-3334"],["dc.title","Assessment of 3 xeroderma pigmentosum group C gene polymorphisms and risk of cutaneous melanoma: a case-control study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

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[["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Buhl, Timo"],["dc.contributor.author","Richter, A."],["dc.contributor.author","Haas, E."],["dc.contributor.author","Holzkamp, R."],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.date.accessioned","2018-11-07T08:52:36Z"],["dc.date.available","2018-11-07T08:52:36Z"],["dc.date.issued","2011"],["dc.format.extent","781"],["dc.identifier.isi","000294596900143"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22210"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Malden"],["dc.relation.issn","1610-0379"],["dc.title","Radiotherapy in thyroid Eye Disease: Ocurrence of pigmented Basal Cell Carcinomas with 15 years Latency"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

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[["dc.bibliographiccitation.firstpage","220"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.lastpage","221"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Kaune, Kjell Matthias"],["dc.contributor.author","Chapuy, Björn"],["dc.contributor.author","Steidl, Christian"],["dc.contributor.author","Ressel, A."],["dc.contributor.author","Baesecke, Joerg"],["dc.contributor.author","Glass, Bertram"],["dc.contributor.author","Neumann, C."],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T10:12:10Z"],["dc.date.available","2018-11-07T10:12:10Z"],["dc.date.issued","2006"],["dc.identifier.isi","000235370600115"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40180"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Blackwell Publishing"],["dc.publisher.place","Oxford"],["dc.relation.conference","33rd Annual Meeting of the Arbeitsgemeinschaft-Dermatologische-Forschung (ADF)"],["dc.relation.eventlocation","Aachen, GERMANY"],["dc.relation.issn","0906-6705"],["dc.title","Sweet-like bullous skin infiltrations in a chronic myeloic leucemia patient treated with tyrosine kinase inhibitors"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Daeschlein, G."],["dc.contributor.author","Ahmed, R."],["dc.contributor.author","Pfeiffer, S."],["dc.contributor.author","Goerlitz, Anke"],["dc.contributor.author","Simon, D."],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Wandke, Dirk"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T09:19:10Z"],["dc.date.available","2018-11-07T09:19:10Z"],["dc.date.issued","2013"],["dc.format.extent","10"],["dc.identifier.isi","000324332500029"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28574"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","The Treatment of chronic venous Leg Ulcers with direct Plasma (PlasmaDerm (R) VU 2010): Results of a single center, two-arm, open-label, randomized, controlled Trial"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Ochsendorf, F."],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Hamm, Henning"],["dc.contributor.author","Hartmann, K."],["dc.contributor.author","Hartmann, M."],["dc.contributor.author","Juenger, M."],["dc.contributor.author","Psotta-Schachtner, C."],["dc.contributor.author","Staender, Sonja"],["dc.contributor.author","von Stebut-Borschitz, E. E."],["dc.contributor.author","Loeser, C."],["dc.date.accessioned","2018-11-07T09:58:43Z"],["dc.date.available","2018-11-07T09:58:43Z"],["dc.date.issued","2015"],["dc.format.extent","111"],["dc.identifier.isi","000360219000315"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37427"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Teaching Situation of the Compartment Dermatology at German medical Faculties"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","647"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.lastpage","649"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Schiller, Stina A."],["dc.contributor.author","Seebode, Christina"],["dc.contributor.author","Wieser, Georg L."],["dc.contributor.author","Goebbels, Sandra"],["dc.contributor.author","Ruhwedel, Torben"],["dc.contributor.author","Horowitz, Mia"],["dc.contributor.author","Rapaport, Debora"],["dc.contributor.author","Sarig, Ofer"],["dc.contributor.author","Sprecher, Eli"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T10:11:12Z"],["dc.date.available","2018-11-07T10:11:12Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1111/exd.13050"],["dc.identifier.isi","000380705500016"],["dc.identifier.pmid","27095090"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40000"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1600-0625"],["dc.relation.issn","0906-6705"],["dc.title","Non-keratinocyte SNAP29 influences epidermal differentiation and hair follicle formation in mice"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Hoffmann, S."],["dc.contributor.author","Buhl, Timo"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Rosenberger, Albert"],["dc.date.accessioned","2018-11-07T09:36:15Z"],["dc.date.available","2018-11-07T09:36:15Z"],["dc.date.issued","2014"],["dc.format.extent","15"],["dc.identifier.isi","000340532500037"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32571"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Determination of Patient Characteristics in Specific Melanoma Subtypes by means of a Prospective Observational Study"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]