Hartmann, Franziska

[["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Therapeutic Drug Monitoring"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Brandhorst, Gunnar"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Petrova, Darinka Todorova"],["dc.contributor.author","Gross, Oliver"],["dc.contributor.author","Armstrong, Victor William"],["dc.contributor.author","Oellerich, M."],["dc.date.accessioned","2018-11-07T11:24:07Z"],["dc.date.available","2018-11-07T11:24:07Z"],["dc.date.issued","2009"],["dc.format.extent","664"],["dc.identifier.isi","000270484600225"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56334"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","11th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology"],["dc.relation.eventlocation","Montreal, CANADA"],["dc.relation.issn","0163-4356"],["dc.title","Mycophenolate Mofetil improves Kidney Function but not Survival in a COL4A3-deficient Mouse Model for Progressive Renal Fibrosis"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Thoms, Kai-Martin"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Zutt, Markus"],["dc.contributor.author","Schoen, Michael Peter"],["dc.date.accessioned","2018-11-07T08:52:30Z"],["dc.date.available","2018-11-07T08:52:30Z"],["dc.date.issued","2011"],["dc.format.extent","7"],["dc.identifier.isi","000294842800023"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/22182"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Malden"],["dc.relation.issn","1610-0379"],["dc.title","Percutaneous transluminal Angioplasty (PTA) in Ulcus cruris mixtum"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Daeschlein, G."],["dc.contributor.author","Ahmed, R."],["dc.contributor.author","Pfeiffer, S."],["dc.contributor.author","Goerlitz, Anke"],["dc.contributor.author","Simon, D."],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Wandke, Dirk"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T09:19:10Z"],["dc.date.available","2018-11-07T09:19:10Z"],["dc.date.issued","2013"],["dc.format.extent","10"],["dc.identifier.isi","000324332500029"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28574"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","The Treatment of chronic venous Leg Ulcers with direct Plasma (PlasmaDerm (R) VU 2010): Results of a single center, two-arm, open-label, randomized, controlled Trial"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Experimental Dermatology"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Daeschlein, G."],["dc.contributor.author","Ahmed, R."],["dc.contributor.author","Goerlitz, Anke"],["dc.contributor.author","Simon, D."],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Wandke, Dirk"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T09:27:22Z"],["dc.date.available","2018-11-07T09:27:22Z"],["dc.date.issued","2013"],["dc.format.extent","E11"],["dc.identifier.isi","000316332000063"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30517"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","40th Annual Meeting of the Association-of-Dermatological-Research"],["dc.relation.eventlocation","Dessau, GERMANY"],["dc.relation.issn","0906-6705"],["dc.title","Treatment of chronic venous leg ulcers with a hand-held DBD plasma generator (PlasmaDerm (R) VU-2010): results of a monocentric, two-armed, open, randomized, and controlled trial (NCT01415622)"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","946"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Der Hautarzt"],["dc.bibliographiccitation.lastpage","948"],["dc.bibliographiccitation.volume","64"],["dc.contributor.author","Lockmann, Anike"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Hofmann, L."],["dc.contributor.author","Wolff, Christian"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Brauns, B."],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.date.accessioned","2018-11-07T09:17:00Z"],["dc.date.available","2018-11-07T09:17:00Z"],["dc.date.issued","2013"],["dc.identifier.doi","10.1007/s00105-013-2669-z"],["dc.identifier.isi","000328492200016"],["dc.identifier.pmid","24337309"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28062"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-1173"],["dc.relation.issn","0017-8470"],["dc.title","Brown Macule with parallel Ridge Pattern on the Palm of a 58-Year-old Woman"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","148"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of the European Academy of Dermatology and Venereology"],["dc.bibliographiccitation.lastpage","155"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Daeschlein, G."],["dc.contributor.author","Ahmed, R."],["dc.contributor.author","Pfeiffer, S."],["dc.contributor.author","Goerlitz, Anke"],["dc.contributor.author","Simon, D."],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Wandke, Dirk"],["dc.contributor.author","Emmert, Steffen"],["dc.date.accessioned","2018-11-07T10:04:03Z"],["dc.date.available","2018-11-07T10:04:03Z"],["dc.date.issued","2015"],["dc.description.abstract","BackgroundCold atmospheric plasma (CAP, i.e. ionized air) is an innovating promising tool in reducing bacteria. ObjectiveWe conducted the first clinical trial with the novel PlasmaDerm((R)) VU-2010 device to assess safety and, as secondary endpoints, efficacy and applicability of 45s/cm(2) cold atmospheric plasma as add-on therapy against chronic venous leg ulcers. MethodsFrom April 2011 to April 2012, 14 patients were randomized to receive standardized modern wound care (n=7) or plasma in addition to standard care (n=7) 3x per week for 8weeks. The ulcer size was determined weekly (Visitrak((R)), photodocumentation). Bacterial load (bacterial swabs, contact agar plates) and pain during and between treatments (visual analogue scales) were assessed. Patients and doctors rated the applicability of plasma (questionnaires). ResultsThe plasma treatment was safe with 2 SAEs and 77 AEs approximately equally distributed among both groups (P=0.77 and P=1.0, Fisher's exact test). Two AEs probably related to plasma. Plasma treatment resulted in a significant reduction in lesional bacterial load (P=0.04, Wilcoxon signed-rank test). A more than 50% ulcer size reduction was noted in 5/7 and 4/7 patients in the standard and plasma groups, respectively, and a greater size reduction occurred in the plasma group (plasma -5.3cm(2), standard: -3.4cm(2)) (non-significant, P=0.42, log-rank test). The only ulcer that closed after 7weeks received plasma. Patients in the plasma group quoted less pain compared to the control group. The plasma applicability was not rated inferior to standard wound care (P=0.94, Wilcoxon-Mann-Whitney test). Physicians would recommend (P=0.06, Wilcoxon-Mann-Whitney test) or repeat (P=0.08, Wilcoxon-Mann-Whitney test) plasma treatment by trend. ConclusionCold atmospheric plasma displays favourable antibacterial effects. We demonstrated that plasma treatment with the PlasmaDerm((R)) VU-2010 device is safe and effective in patients with chronic venous leg ulcers. Thus, larger controlled trials and the development of devices with larger application surfaces are warranted."],["dc.identifier.doi","10.1111/jdv.12490"],["dc.identifier.isi","000346733800024"],["dc.identifier.pmid","24666170"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38612"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1468-3083"],["dc.relation.issn","0926-9959"],["dc.title","Alleviation of chronic venous leg ulcers with a hand-held dielectric barrier discharge plasma generator (PlasmaDerm (R) VU-2010): results of a monocentric, two-armed, open, prospective, randomized and controlled trial (NCT01415622)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","984"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","994"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Hartmann, Franziska"],["dc.contributor.author","Lockmann, Anike"],["dc.contributor.author","Himpel, Okko"],["dc.contributor.author","Kühnle, Ingrid"],["dc.contributor.author","Hensen, Janina"],["dc.contributor.author","Schön, Michael P."],["dc.contributor.author","Thoms, Kai‐Martin"],["dc.date.accessioned","2021-04-14T08:22:56Z"],["dc.date.available","2021-04-14T08:22:56Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1111/ddg.14184_g"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80738"],["dc.language.iso","de"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Orale Propranolol‐ und Neodym:YAG‐Farbstofflaser‐Kombinationstherapie infantiler Hämangiome: eine retrospektive Analyse von 30 Kindern mit 48 Hämangiomen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","73"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Therapeutic Drug Monitoring"],["dc.bibliographiccitation.lastpage","78"],["dc.bibliographiccitation.volume","32"],["dc.contributor.author","Brandhorst, Gunnar"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Petrova, Darinka T"],["dc.contributor.author","Gross, Oliver"],["dc.contributor.author","Miosge, Nicolai"],["dc.contributor.author","Armstrong, Victor W"],["dc.contributor.author","Oellerich, Michael"],["dc.date.accessioned","2021-06-01T10:46:58Z"],["dc.date.available","2021-06-01T10:46:58Z"],["dc.date.issued","2010"],["dc.description.abstract","Within the scope of this study, the potential antifibrotic effect of mycophenolate mofetil (MMF) on COL4A3-deficient mice as an animal model for progressive renal fibrosis was investigated regarding kidney function and survival. Thirty-five animals were randomly assigned to one of five groups and treated with doses of 0, 10, 50, 100, or 150 mg/kg MMF per day, respectively. When increasing somnolence was observed, indicating end-stage renal disease, the mice were euthanized and blood was obtained. Serum concentrations of creatinine, urea nitrogen, total protein, mycophenolic acid (MPA), and mycophenolic acid glucuromide (MPAG) were quantified. The kidney histology was examined using hematoxylin and eosin as well as trichrome staining. The mean overall survival was 65.9 (+/- 6.1) days with no significant difference between the treatment groups (P > 0.05, Mantel-Cox test). Serum predose concentrations of MPA and MPAG showed considerable interindividual variability. There was no correlation between Survival time and MPA or MPAG concentrations (P > 0.05, Spearman rank correlation). However, an apparent decrease in serum creatinine and urea nitrogen concentrations was observed at higher doses of MMF, eg, -54% for creatinine in the 150-mg/kg/day group compared with placebo. A highly significant reciprocal correlation between MPA concentrations and serum creatinine was demonstrated (P < 0.01, r = -0.655, Spearman rank correlation). In conclusion, MMF may be a candidate drug for preserving kidney function in progressive renal fibrosis."],["dc.identifier.doi","10.1097/FTD.0b013e3181c91fc4"],["dc.identifier.isi","000274072000011"],["dc.identifier.pmid","20042922"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85439"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","0163-4356"],["dc.title","Mycophenolic Acid Predose Concentrations and Renal Function in a Mouse Model for Progressive Renal Fibrosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","140"],["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.lastpage","141"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Haenssle, Holger Andreas"],["dc.contributor.author","Mograby, Nerjes"],["dc.contributor.author","Ngassa, A."],["dc.contributor.author","Buhl, Timo"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Emmert, Steffen"],["dc.contributor.author","Schoen, M."],["dc.contributor.author","Rosenberger, Albert"],["dc.contributor.author","Bertsch, Hans-Peter"],["dc.date.accessioned","2018-11-07T09:58:44Z"],["dc.date.available","2018-11-07T09:58:44Z"],["dc.date.issued","2015"],["dc.identifier.isi","000360219000395"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37429"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Primary Melanoma in Association with pre Navi: Results of a prospective Observational Study involving 832 High Risk Patients"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","JDDG Journal der Deutschen Dermatologischen Gesellschaft"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Brehmer, Franziska"],["dc.contributor.author","Baltzer, Anne"],["dc.contributor.author","Forkel, Susann"],["dc.contributor.author","Al Ghazal, Philipp"],["dc.contributor.author","Schoen, Michael Peter"],["dc.contributor.author","Thoms, Kai Martin"],["dc.contributor.author","Kretschmer, Lutz"],["dc.date.accessioned","2018-11-07T09:53:40Z"],["dc.date.available","2018-11-07T09:53:40Z"],["dc.date.issued","2015"],["dc.format.extent","41"],["dc.identifier.isi","000360219800091"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36374"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.issn","1610-0387"],["dc.relation.issn","1610-0379"],["dc.title","Complete Remission of cutaneous Melanoma Metastases with Combination Therapy of Ipilimumab and Diphenylcyclopropenone (DPCP)"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]