Grimm, Michael

[["dc.bibliographiccitation.firstpage","106"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","113"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","von Lewinski, Dirk"],["dc.contributor.author","Gasser, Robert"],["dc.contributor.author","Rainer, Peter P."],["dc.contributor.author","Huber, Marie-Sophie"],["dc.contributor.author","Wilhelm, Bastian"],["dc.contributor.author","Roessl, Ulrich"],["dc.contributor.author","Haas, Tobias"],["dc.contributor.author","Wasler, Andrae"],["dc.contributor.author","Grimm, Michael"],["dc.contributor.author","Bisping, Egbert"],["dc.contributor.author","Pieske, Burkert M."],["dc.date.accessioned","2018-11-07T08:46:11Z"],["dc.date.available","2018-11-07T08:46:11Z"],["dc.date.issued","2010"],["dc.description.abstract","Insulin-dependent positive inotropic effects (PIE) are partially Ca(2+) independent. This mechanism is potentially glucose dependent. In contrast to most animal species, human myocardium expresses high levels of sodium-glucose-transporter-1 (SGLT-1) mRNA besides the common glucose-transporters-1 and -4 (GLUT1, GLUT4). We used ventricular myocardium from 61 end-stage failing human hearts (ischaemic cardiomyopathy, ICM and dilated cardiomyopathy, DCM) and 13 non-failing donor hearts. The effect of insulin on isometric twitch force was examined with or without blocking of PI3-kinase, GLUT4-translocation, or SGLT-1. Substrate-dependent (glucose vs. pyruvate vs. palmitoyl-carnitine) effects were tested in atrial myocardium. mRNA expression of glucose transporters was analysed. Insulin increased developed force by 122 +/- 7.4, 121.7 +/- 2.5, and 134.1 +/- 5.7% in non-failing, DCM, and ICM (P < 0.05 vs. DCM), respectively. Positive inotropic effect was partially blunted by inhibition of PI-3-kinase, GLUT4, or SGLT1. Combined inhibition of PI3-kinase and glucose-transport completely abolished PIE. Positive inotropic effect was significantly stronger in glucose-containing solution compared with pyruvate or palmitoyl-carnitine containing. mRNA expression showed only a tendency towards elevated GLUT4-expression in ICM. Positive inotropic effect of insulin is pronounced in ICM, but underlying mechanisms are unaltered. The Ca(2+)-independent PIE of insulin is mediated via glucose-transporters. Together with the Ca(2+)-dependent PI-3-kinase mediated pathway, it is responsible for the entire PIE. Substrate-dependency affirms a glucose-dependent part of the PIE."],["dc.description.sponsorship","Merck KGaA, Darmstadt, Germany"],["dc.identifier.doi","10.1093/eurjhf/hfp191"],["dc.identifier.isi","000273868800003"],["dc.identifier.pmid","20083620"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20628"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1388-9842"],["dc.title","Functional effects of glucose transporters in human ventricular myocardium"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","318"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.lastpage","329"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Pacher, R."],["dc.contributor.author","Stanek, B."],["dc.contributor.author","Hulsmann, M."],["dc.contributor.author","Berger, R."],["dc.contributor.author","Siegel, A."],["dc.contributor.author","Daneschvar, H."],["dc.contributor.author","Rodler, S."],["dc.contributor.author","Frey, B."],["dc.contributor.author","Grimm, M."],["dc.contributor.author","Laufer, G."],["dc.date.accessioned","2020-11-05T14:51:28Z"],["dc.date.available","2020-11-05T14:51:28Z"],["dc.date.issued","1997"],["dc.identifier.doi","10.1093/oxfordjournals.eurheartj.a015235"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/68218"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-352.3"],["dc.relation.eissn","1522-9645"],["dc.relation.issn","0195-668X"],["dc.title","Prostaglandin E1--bridge to cardiac transplantation: Technique, dosage, results"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","759"],["dc.bibliographiccitation.journal","Journal of the Royal Statistical Society Series A (Statistics in Society)"],["dc.bibliographiccitation.lastpage","784"],["dc.bibliographiccitation.volume","174"],["dc.contributor.author","Graeb, Johannes"],["dc.contributor.author","Grimm, Michael"],["dc.date.accessioned","2018-11-07T09:01:36Z"],["dc.date.available","2018-11-07T09:01:36Z"],["dc.date.issued","2011"],["dc.description.abstract","Empirical evidence suggests that regional disparities in income are often very wide, that these disparities do not necessarily disappear as economies grow and that these disparities are themselves a major driver of growth. We use a novel approach based on multilevel modelling to decompose the sources of inequality in household incomes in Burkina Faso. We show that differences in income across space are explained not only by the spatial concentration of households with favourable characteristics but to a large extent also by disparities in community endowments. Climatic differences across regions do matter, also, but to a much smaller extent. On the basis of the findings, it would be worth assessing the potential effects of policies which build and enhance infrastructure that connects communities complemented by interventions targeted to specific villages that particularly lag behind."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft [GR3097/1-1]"],["dc.identifier.doi","10.1111/j.1467-985X.2010.00686.x"],["dc.identifier.isi","000292339000013"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24471"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","0964-1998"],["dc.title","Inequality in Burkina Faso-to what extent do household, community and regional factors matter?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","754"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.lastpage","758"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Grimm, Michael"],["dc.date.accessioned","2018-11-07T10:01:30Z"],["dc.date.available","2018-11-07T10:01:30Z"],["dc.date.issued","2006"],["dc.identifier.doi","10.1086/500093"],["dc.identifier.isi","000236978900012"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38034"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Univ Chicago Press"],["dc.publisher.place","Chicago"],["dc.relation.issn","0013-0079"],["dc.title","The microeconomics of income distribution dynamics in East Asia and Latin America"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.seriesnr","14"],["dc.contributor.author","Klasen, Stephan"],["dc.contributor.author","Grimm, Michael"],["dc.date.accessioned","2018-06-05T13:50:38Z"],["dc.date.available","2018-06-05T13:50:38Z"],["dc.date.issued","2009"],["dc.description.abstract","There is a well-known debate about the role of institutions in explaining the long-term development of countries. We believe there is value-added to consider the institutions hypothesis at the micro level within a country to analyze the exact transmission channels linking endogenous institutional change to development outcomes. Given the central importance of agricultural productivity improvements for initiating the process of economic development, we focus on the transmission mechanisms that lead to the emergence of institutions relevant for agricultural development, thereby incorporating insights from the literatures on demographic influences of institutional change, induced innovations, as well as the central role of land rights in our analysis. Our main argument is that in conditions of relative land abundance, geographic factors influence rural-rural migration flows to geographically well-endowed regions which in turn give rise to migration-induced land scarcity. Land scarcity in turn, provides incentives to formalize landownership. Eventually, formalized land rights increase investment in land and enhance the adoption of new and better technologies promoting agricultural growth and economic development. We provide empirical evidence for this hypothesis using longitudinal village and household survey data from Indonesia."],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/14898"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.publisher","Courant Research Centre PEG"],["dc.relation.crisseries","Discussion Papers (Courant Research Centre \"Poverty, Equity and Growth in Developing and Transition Countries: Statistical Methods and Empirical Analysis\")"],["dc.relation.ispartofseries","Courant Research Centre: Poverty, Equity and Growth - Discussion Papers; 14"],["dc.title","Endogenous Institutional Change and Economic Development: A Micro-Level Analysis of Transmission Channels"],["dc.type","working_paper"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","80"],["dc.bibliographiccitation.issue","1-2"],["dc.bibliographiccitation.journal","Transplantation Proceedings"],["dc.bibliographiccitation.lastpage","81"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Frey, B"],["dc.contributor.author","Zuckermann, A"],["dc.contributor.author","Koller-Strametz, J"],["dc.contributor.author","Rödler, S"],["dc.contributor.author","Hülsmann, M"],["dc.contributor.author","Stanek, B"],["dc.contributor.author","Grimm, M"],["dc.contributor.author","Laufer, G"],["dc.contributor.author","Pacher, R"],["dc.date.accessioned","2020-11-05T14:51:45Z"],["dc.date.available","2020-11-05T14:51:45Z"],["dc.date.issued","1999"],["dc.identifier.doi","10.1016/S0041-1345(98)01446-8"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/68337"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-352.3"],["dc.relation.issn","0041-1345"],["dc.title","Effects of continuous, long-term therapy with prostaglandin E1 preoperatively on outcome after heart transplantation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","411"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Land Economics"],["dc.bibliographiccitation.lastpage","434"],["dc.bibliographiccitation.volume","91"],["dc.contributor.author","Grimm, M."],["dc.contributor.author","Klasen, S."],["dc.date.accessioned","2018-05-21T19:27:59Z"],["dc.date.available","2018-05-21T19:27:59Z"],["dc.date.issued","2015"],["dc.description.abstract","We explore the role played by migration-induced population pressure for the endogenous adoption of formal land titles and subsequent investments in land in Central Sulawesi, Indonesia. Using original village- and household-level data we provide evidence that migration pressure increased the incentives to formalize landownership. The adoption of formal land rights was in turn associated with increased expenditures for agricultural inputs and investment in trees, terraces, ditches, and irrigation systems. We show that the availability of a demand-driven land titling system has been critical for increased agricultural intensification in this Indonesian setting."],["dc.identifier.doi","10.3368/le.91.3.411"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/14698"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation","SFB 990: Ökologische und sozioökonomische Funktionen tropischer Tieflandregenwald-Transformationssysteme (Sumatra, Indonesien)"],["dc.relation","SFB 990 | C | C04: Mitigating trade-offs between economic and ecological functions and services through certification"],["dc.subject.gro","sfb990_reviews"],["dc.title","Migration Pressure, Tenure Security, and Agricultural Intensification: Evidence from Indonesia"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.subtype","overview_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","193"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Oxford Economic Papers"],["dc.bibliographiccitation.lastpage","211"],["dc.bibliographiccitation.volume","60"],["dc.contributor.author","Grimm, Michael"],["dc.contributor.author","Harttgen, Kenneth"],["dc.date.accessioned","2018-11-07T11:16:48Z"],["dc.date.available","2018-11-07T11:16:48Z"],["dc.date.issued","2008"],["dc.description.abstract","Whereas life expectancy continues to increase in most industrialized countries, many developing and transition countries are today confronted with decreases in life expectancy. Usual measures employed to compare welfare over time and space fail to deal with such demographic change and may lead to the so-called repugnant conclusion that lower life expectancy involves higher welfare per capita. We illustrate this type of transmission channel using various welfare criteria and reference populations. We also consider feed-back effects from the demography on the economy using a neo-classical growth model. We show that the repugnant conclusion can be avoided if we choose a lifetime welfare measure instead of a period (or snapshot) welfare measure. All concepts are illustrated empirically using a small sample of developed and developing countries."],["dc.identifier.doi","10.1093/oep/gpm025"],["dc.identifier.isi","000254294900001"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54676"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0030-7653"],["dc.title","Longer life, higher welfare"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","231"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Policy Modeling"],["dc.bibliographiccitation.lastpage","247"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Grimm, Michael"],["dc.date.accessioned","2018-11-07T11:20:45Z"],["dc.date.available","2018-11-07T11:20:45Z"],["dc.date.issued","2005"],["dc.description.abstract","I use a dynamic microsimulation model to analyse the distributional effects of educational policies in Cote d' Ivoire. The simulations replicate several policies in force or subject to debate in this country. The direct effects between education and income as well as the different transmission channels, such as occupational choices and household composition, are analysed. The simulations show that even if the most optimistic policy considered was really set up the effects on poverty would be very modest as long as returns to education remain constant and the labour market segmented. This has interesting implications for the elaboration of poverty reduction strategies. (c) 2005 Society for Policy Modeling. Published by Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.jpolmod.2004.12.002"],["dc.identifier.isi","000228715200007"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/55614"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0161-8938"],["dc.title","Educational policies and poverty reduction in Cote d'Ivoire"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","393"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Population Research and Policy Review"],["dc.bibliographiccitation.lastpage","407"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Cogneau, Denis"],["dc.contributor.author","Grimm, Michael"],["dc.date.accessioned","2018-11-07T09:30:58Z"],["dc.date.available","2018-11-07T09:30:58Z"],["dc.date.issued","2006"],["dc.description.abstract","Lack of knowledge about differential AIDS mortality seriously hampers the study of the economic impact of AIDS in developing countries. We derive HIV infection risk differentials by age, education, and other microeconomic characteristics using the Ivorian Demographic and Health Survey. Our model is based on econometrically estimated equations using commonly available variables, therefore it can be used whenever such a survey is available but there is no representative information about HIV infection by socioeconomic group. For instance, we found that educated people have a higher risk of HIV infection, because they are more likely to have several sexual partners. However, this effect is partly offset by a higher probability of condom use relative to less educated people. The identification of the socioeconomic characteristics of low and high risk groups seems indispensable to set up adequate AIDS prevention and therapy policies in developing countries."],["dc.identifier.doi","10.1007/s11113-006-9008-3"],["dc.identifier.isi","000242439400005"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/31435"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0167-5923"],["dc.title","Socioeconomic status, sexual behavior, and differential AIDS mortality: evidence from Cote d'Ivoire"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]