Bräuer, Anselm

[["dc.bibliographiccitation.firstpage","842"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Der Anaesthesist"],["dc.bibliographiccitation.lastpage","850"],["dc.bibliographiccitation.volume","59"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Waeschle, Reiner M."],["dc.contributor.author","Heise, Daniel"],["dc.contributor.author","Perl, Tal Naggan"],["dc.contributor.author","Hinz, Jose Maria"],["dc.contributor.author","Quintel, M."],["dc.contributor.author","Bauer, M."],["dc.date.accessioned","2018-11-07T08:39:25Z"],["dc.date.available","2018-11-07T08:39:25Z"],["dc.date.issued","2010"],["dc.description.abstract","Despite the broad application of intraoperative warming new studies still show a high incidence of perioperative hypothermia. Therefore a prewarming program in the preoperative holding area was started. The efficacy of the prewarming program was assessed with an accompanying quality assurance check sheet over a period of 3 months. During the 3 month test period 127 patients were included. The median length from arrival in the holding area to beginning prewarming was 6 min and the average duration of prewarming was 46 +/- 38 min. During prewarming the core temperature rose by 0.3 +/- 0.4A degrees C to 37.1 +/- 0.5A degrees C and decreased to 36.3 +/- 0.5A degrees C after induction of anesthesia. At the end of the operation the core temperature was 36.4 +/- 0.5A degrees C and 14% of the patients were hypothermic. These data allow 2 conclusions: 1. Prewarming in the holding area is possible with a sufficient duration. 2. Prewarming is highly efficient even when performed over a relatively short duration."],["dc.identifier.doi","10.1007/s00101-010-1772-0"],["dc.identifier.isi","000281844600007"],["dc.identifier.pmid","20703440"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18992"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0003-2417"],["dc.title","Preoperative prewarming as a routine measure. First experiences"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e0284"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Critical Care Explorations"],["dc.bibliographiccitation.lastpage","5"],["dc.bibliographiccitation.volume","2"],["dc.contributor.author","Hofmann-Winkler, Heike"],["dc.contributor.author","Moerer, Onnen"],["dc.contributor.author","Alt-Epping, Sabine"],["dc.contributor.author","Bräuer, Anselm"],["dc.contributor.author","Büttner, Benedikt"],["dc.contributor.author","Müller, Martin"],["dc.contributor.author","Fricke, Torben"],["dc.contributor.author","Grundmann, Julian"],["dc.contributor.author","Harnisch, Lars-Olav"],["dc.contributor.author","Heise, Daniel"],["dc.contributor.author","Kernchen, Andrea"],["dc.contributor.author","Pressler, Meike"],["dc.contributor.author","Stephani, Caspar"],["dc.contributor.author","Tampe, Björn"],["dc.contributor.author","Kaul, Artur"],["dc.contributor.author","Gärtner, Sabine"],["dc.contributor.author","Kramer, Stefanie"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.author","Winkler, Martin Sebastian"],["dc.date.accessioned","2020-11-27T11:23:20Z"],["dc.date.accessioned","2021-10-27T13:22:21Z"],["dc.date.available","2020-11-27T11:23:20Z"],["dc.date.available","2021-10-27T13:22:21Z"],["dc.date.issued","2020"],["dc.description.abstract","Objectives: Severe acute respiratory syndrome coronavirus 2 cell entry depends on angiotensin-converting enzyme 2 and transmembrane serine protease 2 and is blocked in cell culture by camostat mesylate, a clinically proven protease inhibitor. Whether camostat mesylate is able to lower disease burden in coronavirus disease 2019 sepsis is currently unknown. Design: Retrospective observational case series. Setting: Patient treated in ICU of University hospital Göttingen, Germany. Patients: Eleven critical ill coronavirus disease 2019 patients with organ failure were treated in ICU. Interventions: Compassionate use of camostat mesylate (six patients, camostat group) or hydroxychloroquine (five patients, hydroxychloroquine group). Measurements and Main Results: Clinical courses were assessed by Sepsis-related Organ Failure Assessment score at days 1, 3, and 8. Further, viral load, oxygenation, and inflammatory markers were determined. Sepsis-related Organ Failure Assessment score was comparable between camostat and hydroxychloroquine groups upon ICU admission. During observation, the Sepsis-related Organ Failure Assessment score decreased in the camostat group but remained elevated in the hydroxychloroquine group. The decline in disease severity in camostat mesylate treated patients was paralleled by a decline in inflammatory markers and improvement of oxygenation. Conclusions: The severity of coronavirus disease 2019 decreased upon camostat mesylate treatment within a period of 8 days and a similar effect was not observed in patients receiving hydroxychloroquine. Camostat mesylate thus warrants further evaluation within randomized clinical trials."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2020"],["dc.identifier.doi","10.1097/CCE.0000000000000284"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17663"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/92088"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.relation.eissn","2639-8028"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","Camostat Mesylate May Reduce Severity of Coronavirus Disease 2019 Sepsis: A First Observation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","58"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Anaesthesia and Intensive Care"],["dc.bibliographiccitation.lastpage","66"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Wetz, A. J."],["dc.contributor.author","Richardt, E. M."],["dc.contributor.author","Schotola, H."],["dc.contributor.author","Bauer, M."],["dc.contributor.author","Bräuer, A."],["dc.date.accessioned","2020-12-10T18:38:26Z"],["dc.date.available","2020-12-10T18:38:26Z"],["dc.date.issued","2017"],["dc.description.abstract","Acute kidney injury (AKI) is frequently observed after cardiac surgery (CS) with cardiopulmonary bypass (CPB). Multiple mechanisms underlie this phenomenon, including CPB-dependent haemolysis. Haemoglobin is released during haemolysis, and free haemoglobin (frHb) causes tubular cell injury after exceeding the binding capacity of haptoglobin (Hp). The objective of this study was to investigate the influence of perioperative changes in frHb and Hp levels on the incidence of CS-associated (CSA) AKI. After receiving local ethics committee approval and obtaining informed consent from our patients, we analysed the data pertaining to 154 patients undergoing CPB surgery. We recorded frHb and Hp concentrations pre-, intra- and postoperatively and defined AKI using the Kidney Disease Improving Global Outcomes (KDIGO) classification. We observed that frHb levels increased significantly during surgery and then decreased at ten hours thereafter and that Hp levels decreased during surgery and remained at low levels until the first postoperative day. We noted a moderate negative correlation between frHb and Hp levels. AKI was identified in 45.5% of patients; however, there was no significant difference in frHb or Hp levels between patients with and without AKI. We did not observe a relationship between frHb or Hp levels and CSA AKI and thus could not confirm the hypothesis that patients with higher baseline Hp concentrations experience a lower incidence of AKI than patients with lower baseline Hp concentrations."],["dc.identifier.doi","10.1177/0310057X1704500109"],["dc.identifier.eissn","1448-0271"],["dc.identifier.isi","000392257300009"],["dc.identifier.issn","0310-057X"],["dc.identifier.pmid","28072936"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77317"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Australian Soc Anaesthetists"],["dc.relation.issn","1448-0271"],["dc.relation.issn","0310-057X"],["dc.title","Haptoglobin and free haemoglobin during cardiac surgery-is there a link to acute kidney injury?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","612"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Der Anaesthesist"],["dc.bibliographiccitation.lastpage","+"],["dc.bibliographiccitation.volume","64"],["dc.contributor.author","Waeschle, Reiner M."],["dc.contributor.author","Russo, Sebastian Giuseppe"],["dc.contributor.author","Sliwa, Bodo"],["dc.contributor.author","Bleeker, F."],["dc.contributor.author","Russo, M."],["dc.contributor.author","Bauer, M."],["dc.contributor.author","Braeuer, Anselm"],["dc.date.accessioned","2018-11-07T09:53:47Z"],["dc.date.available","2018-11-07T09:53:47Z"],["dc.date.issued","2015"],["dc.description.abstract","Improvement of quality of care and patient safety while decreasing costs are major challenges in healthcare systems. This challenge includes the avoidance of perioperative hypothermia to reduce the associated adverse effects, length of stay and treatment costs. Due to the medical and economic relevance the national S3 guidelines for the prevention of perioperative hypothermia were recently published. This study presents and analyses the reality of utilization of thermal management in German hospitals depending on the size of the hospital, which is based on the number of beds. Based on the data of an online survey among all members of the German Society of Anesthesiology and Intensive Care Medicine about perioperative thermal management, a subgroup analysis differentiating between the size of hospitals was performed. The survey included questions about the structural and organizational conditions, the practical implementation of temperature measurement and warming therapy and the developmental status of clinical standard operating procedures (SOP) and educational training. Comparing the structural quality, major differences were found with respect to the availability of core body temperature measurement and the provision of warming devices especially at different peripheral anesthesia workplaces as well as the existence of SOPs and educational training. The availability increased with hospital size. With respect to process quality, the frequency of prewarming increased with hospital size as well as the frequency of intraoperative temperature measurements during different anesthesia procedures. Major differences were found in several aspects of perioperative thermal management depending on the hospital size. The main potential for improvement was found in smaller hospitals. Developmental needs primarily exist in the configuration of peripheral anesthesia workplaces, educational training, implementation of SOPs and prewarming of patients."],["dc.identifier.doi","10.1007/s00101-015-0057-z"],["dc.identifier.isi","000359808400009"],["dc.identifier.pmid","26194652"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36401"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-055X"],["dc.relation.issn","0003-2417"],["dc.title","Perioperative thermal management in Germany varies depending on the hospital size"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","205"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Anesthesiology"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Koh, Wenjun"],["dc.contributor.author","Chakravarthy, Murali"],["dc.contributor.author","Simon, Edgard"],["dc.contributor.author","Rasiah, Raveenthiran"],["dc.contributor.author","Charuluxananan, Somrat"],["dc.contributor.author","Kim, Tae-Yop"],["dc.contributor.author","Chew, Sophia T. H."],["dc.contributor.author","Bräuer, Anselm"],["dc.contributor.author","Ti, Lian Kah"],["dc.date.accessioned","2021-09-01T06:38:32Z"],["dc.date.available","2021-09-01T06:38:32Z"],["dc.date.issued","2021"],["dc.description.abstract","Abstract Background Anesthesia leads to impairments in central and peripheral thermoregulatory responses. Inadvertent perioperative hypothermia is hence a common perioperative complication, and is associated with coagulopathy, increased surgical site infection, delayed drug metabolism, prolonged recovery, and shivering. However, surveys across the world have shown poor compliance to perioperative temperature management guidelines. Therefore, we evaluated the prevalent practices and attitudes to perioperative temperature management in the Asia–Pacific region, and determined the individual and institutional factors that lead to noncompliance. Methods A 40-question anonymous online questionnaire was distributed to anesthesiologists and anesthesia trainees in six countries in the Asia–Pacific (Singapore, Malaysia, Philippines, Thailand, India and South Korea). Participants were polled about their current practices in patient warming and temperature measurement across the preoperative, intraoperative and postoperative periods. Questions were also asked regarding various individual and environmental barriers to compliance. Results In total, 1154 valid survey responses were obtained and analyzed. 279 (24.2%) of respondents prewarm, 508 (44.0%) perform intraoperative active warming, and 486 (42.1%) perform postoperative active warming in the majority of patients. Additionally, 531 (46.0%) measure temperature preoperatively, 767 (67.5%) measure temperature intraoperatively during general anesthesia, and 953 (82.6%) measure temperature postoperatively in the majority of patients. The availability of active warming devices in the operating room ( p  < 0.001, OR 10.040), absence of financial restriction ( p  < 0.001, OR 2.817), presence of hospital training courses ( p  = 0.011, OR 1.428), and presence of a hospital SOP ( p  < 0.001, OR 1.926) were significantly associated with compliance to intraoperative active warming. Conclusions Compliance to international perioperative temperature management guidelines in Asia–Pacific remains poor, especially in small hospitals. Barriers to compliance were limited temperature management equipment, lack of locally-relevant standard operating procedures and training. This may inform international guideline committees on the needs of developing countries, or spur local anesthesiology societies to publish their own national guidelines."],["dc.description.abstract","Abstract Background Anesthesia leads to impairments in central and peripheral thermoregulatory responses. Inadvertent perioperative hypothermia is hence a common perioperative complication, and is associated with coagulopathy, increased surgical site infection, delayed drug metabolism, prolonged recovery, and shivering. However, surveys across the world have shown poor compliance to perioperative temperature management guidelines. Therefore, we evaluated the prevalent practices and attitudes to perioperative temperature management in the Asia–Pacific region, and determined the individual and institutional factors that lead to noncompliance. Methods A 40-question anonymous online questionnaire was distributed to anesthesiologists and anesthesia trainees in six countries in the Asia–Pacific (Singapore, Malaysia, Philippines, Thailand, India and South Korea). Participants were polled about their current practices in patient warming and temperature measurement across the preoperative, intraoperative and postoperative periods. Questions were also asked regarding various individual and environmental barriers to compliance. Results In total, 1154 valid survey responses were obtained and analyzed. 279 (24.2%) of respondents prewarm, 508 (44.0%) perform intraoperative active warming, and 486 (42.1%) perform postoperative active warming in the majority of patients. Additionally, 531 (46.0%) measure temperature preoperatively, 767 (67.5%) measure temperature intraoperatively during general anesthesia, and 953 (82.6%) measure temperature postoperatively in the majority of patients. The availability of active warming devices in the operating room ( p  < 0.001, OR 10.040), absence of financial restriction ( p  < 0.001, OR 2.817), presence of hospital training courses ( p  = 0.011, OR 1.428), and presence of a hospital SOP ( p  < 0.001, OR 1.926) were significantly associated with compliance to intraoperative active warming. Conclusions Compliance to international perioperative temperature management guidelines in Asia–Pacific remains poor, especially in small hospitals. Barriers to compliance were limited temperature management equipment, lack of locally-relevant standard operating procedures and training. This may inform international guideline committees on the needs of developing countries, or spur local anesthesiology societies to publish their own national guidelines."],["dc.identifier.doi","10.1186/s12871-021-01414-6"],["dc.identifier.pii","1414"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88954"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-455"],["dc.relation.eissn","1471-2253"],["dc.title","Perioperative temperature management: a survey of 6 Asia–Pacific countries"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","375"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","MINERVA ANESTESIOLOGICA"],["dc.bibliographiccitation.lastpage","383"],["dc.bibliographiccitation.volume","75"],["dc.contributor.author","Quintel, M."],["dc.contributor.author","Braeuer, Anselm"],["dc.date.accessioned","2018-11-07T08:29:31Z"],["dc.date.available","2018-11-07T08:29:31Z"],["dc.date.issued","2009"],["dc.description.abstract","Currently, tracheostomy represents an established procedure for airway management in critically ill patients who require long-term respiratory support, and it is one of the most frequently performed surgical procedures in critically ill patients. It offers a number of practical and theoretical advantages when compared to conventional translaryngeal oro- or nasotracheal intubation, but is also associated with a number of serious complications. In the last 20 years, several retrospective studies, randomized prospective trials, and meta-analyses have been published to determine the best timing for tracheostomy. However, these studies presented conflicting results. All studies performed so far in a prospective randomized fashion were relatively small and underpowered. Currently, several large controlled randomized studies are underway that will hopefully help physicians make better evidence-based decisions on the timing of tracheostomy. Based on our current knowledge, the following recommendations might be made on a low level of evidence: on day 2 or 3 after onset of mechanical ventilation (>48 h of mechanical ventilation or need for an artificial airway) tracheostomy should be seriously considered. Before decisions are made, several questions should be answered: Is the situation suitable for tracheostomy? Are there relevant contraindications for the performance of a tracheostomy? What is the most likely course of the underlying respiratory insufficiency? What is the likelihood the patient will stay in need of invasive mechanical ventilation for more than a week, either because of an ongoing impairment of oxygenation, weaning failure, upper airway obstruction, coma or a swallowing disorder? If no relevant contraindication is present and if the need for invasive mechanical ventilation can be expected to last for more than one week, tracheostomy should be planned and performed within the next 2 days."],["dc.identifier.isi","000266482100005"],["dc.identifier.pmid","18946428"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/16673"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Edizioni Minerva Medica"],["dc.relation.issn","0375-9393"],["dc.title","Timing of tracheostomy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","287"],["dc.bibliographiccitation.journal","ANASTHESIOLOGIE & INTENSIVMEDIZIN"],["dc.bibliographiccitation.lastpage","+"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Russo, M."],["dc.contributor.author","Nickel, E. A."],["dc.contributor.author","Bauer, M."],["dc.contributor.author","Russo, Sebastian Giuseppe"],["dc.date.accessioned","2018-11-07T09:56:16Z"],["dc.date.available","2018-11-07T09:56:16Z"],["dc.date.issued","2015"],["dc.description.abstract","The 2014 S3 Guideline for the prevention of perioperative hypothermia (see also short version on page 308 of this issue) recently published by the AWMF (Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften) emphasises the importance of an optimized perioperative thermal management for the prevention of adverse effects of hypothermia and the resulting economic consequences. However, it is still unclear how perioperative thermal management is carried out in Germany. Therefore, we conducted an online survey which included all members of the German Society of Anaesthesiology and Intensive Care Medicine. The questionnaire contained mainly questions focusing on the following areas: infrastructure of the workplaces, equipment used to measure core temperature and to warm patients, actual perioperative thermal management and available standards. The results were compared to the recommendations of the 2014 S3 Guideline for the prevention of perioperative hypothermia. Especially in the central O.R. units most of the recommendations have already been implemented. However, the actual prewarming strategies do not comply with the recommendations, so that there seems to be a large potential for improvement. Other areas with potential for improvement are the anaesthesia workplaces outside the central O.R. unit like emergency rooms, delivery rooms and radiological and cardiological intervention rooms. Furthermore, a relevant deficit exists in the training of physicians and in the introduction and implementation of standard operating procedures. In summary, our results show that some relevant aspects of perioperative thermal management can be improved to enhance patient safety and to reduce the economic consequences of perioperative hypothermia."],["dc.identifier.isi","000357846600003"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36922"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Aktiv Druck & Verlag Gmbh"],["dc.relation.issn","0170-5334"],["dc.title","Perioperative thermal management in Germany - Results of an online survey"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Journal of Clinical Monitoring and Computing"],["dc.contributor.author","Nemeth, Marcus"],["dc.contributor.author","Lovric, Marijana"],["dc.contributor.author","Asendorf, Thomas"],["dc.contributor.author","Bräuer, Anselm"],["dc.contributor.author","Miller, Clemens"],["dc.date.accessioned","2021-04-14T08:32:08Z"],["dc.date.available","2021-04-14T08:32:08Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1007/s10877-020-00609-5"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83822"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1573-2614"],["dc.relation.issn","1387-1307"],["dc.title","Intraoperative zero-heat-flux thermometry overestimates esophageal temperature by 0.26 °C: an observational study in 100 infants and young children"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","7541"],["dc.bibliographiccitation.issue","14"],["dc.bibliographiccitation.journal","International Journal of Environmental Research and Public Health"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Nemeth, Marcus"],["dc.contributor.author","Miller, Clemens"],["dc.contributor.author","Bräuer, Anselm"],["dc.date.accessioned","2021-08-12T07:45:58Z"],["dc.date.available","2021-08-12T07:45:58Z"],["dc.date.issued","2021"],["dc.description.abstract","Background: First described by paediatric anaesthesiologists, perioperative hypothermia is one of the earliest reported side effects of general anaesthesia. Deviations from normothermia are associated with numerous complications and adverse outcomes, with infants and small children at the highest risk. Nowadays, maintenance of normothermia is an important quality metric in paediatric anaesthesia. Methods: This review is based on our collection of publications regarding perioperative hypothermia and was supplemented with pertinent publications from a MEDLINE literature search. Results: We provide an overview on perioperative hypothermia in the paediatric patient, including definition, history, incidence, development, monitoring, risk factors, and adverse events, and provide management recommendations for its prevention. We also summarize the side effects and complications of perioperative temperature management. Conclusions: Perioperative hypothermia is still common in paediatric patients and may be attributed to their vulnerable physiology, but also may result from insufficient perioperative warming. An effective perioperative warming strategy incorporates the maintenance of normothermia during transportation, active warming before induction of anaesthesia, active warming during anaesthesia and surgery, and accurate measurement of core temperature. Perioperative temperature management must also prevent hyperthermia in children."],["dc.description.abstract","Background: First described by paediatric anaesthesiologists, perioperative hypothermia is one of the earliest reported side effects of general anaesthesia. Deviations from normothermia are associated with numerous complications and adverse outcomes, with infants and small children at the highest risk. Nowadays, maintenance of normothermia is an important quality metric in paediatric anaesthesia. Methods: This review is based on our collection of publications regarding perioperative hypothermia and was supplemented with pertinent publications from a MEDLINE literature search. Results: We provide an overview on perioperative hypothermia in the paediatric patient, including definition, history, incidence, development, monitoring, risk factors, and adverse events, and provide management recommendations for its prevention. We also summarize the side effects and complications of perioperative temperature management. Conclusions: Perioperative hypothermia is still common in paediatric patients and may be attributed to their vulnerable physiology, but also may result from insufficient perioperative warming. An effective perioperative warming strategy incorporates the maintenance of normothermia during transportation, active warming before induction of anaesthesia, active warming during anaesthesia and surgery, and accurate measurement of core temperature. Perioperative temperature management must also prevent hyperthermia in children."],["dc.description.sponsorship","3M San Antonio, TX, USA"],["dc.identifier.doi","10.3390/ijerph18147541"],["dc.identifier.pii","ijerph18147541"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88585"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-448"],["dc.publisher","MDPI"],["dc.relation.eissn","1660-4601"],["dc.rights","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Perioperative Hypothermia in Children"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","308"],["dc.bibliographiccitation.journal","ANASTHESIOLOGIE & INTENSIVMEDIZIN"],["dc.bibliographiccitation.lastpage","315"],["dc.bibliographiccitation.volume","56"],["dc.contributor.author","Torossian, Alexander"],["dc.contributor.author","Braeuer, Anselm"],["dc.contributor.author","Hocker, J."],["dc.contributor.author","Bein, B."],["dc.contributor.author","Wulf, Hinnerk"],["dc.contributor.author","Horn, E.-P."],["dc.date.accessioned","2018-11-07T09:56:16Z"],["dc.date.available","2018-11-07T09:56:16Z"],["dc.date.issued","2015"],["dc.description.abstract","Introduction: 26-90% of all patients undergoing elective surgery suffer from inadvertent postoperative hypothermia, i.e., a core body temperature below 36 degrees C. Compared to normothermic patients, these patients have more frequent wound infections (relative risk (RR) 3.25, 95% confidence interval (CI) 1.35-7.84, cardiac complications (RR 4.49, CI 1.00-20.16), and blood transfusions (RR 1.33, CI 1.06-1.66). Hypothermic patients feel uncomfortable, and shivering raises oxygen consumption by about 40%. Methods: This guideline is based on a systematic review of the literature up to and including October 2012 and a further one from November 2012 to August 2014. The recommendations were developed and agreed upon by representatives of five medical specialty societies in a structured consensus process. Results: The patient's core temperature should be measured 1-2 hours before the start of anesthesia, and either continuously or every 15 minutes during surgery. Depending on the nature of the operation, the site of temperature measurement should be oral, naso-/oropharyngeal, esophageal, vesical, or tympanic (direct). The patient should be actively prewarmed 20-30 minutes before surgery to counteract the decline in temperature. Prewarmed patients must be actively warmed intraoperatively as well if the planned duration of anesthesia is longer than 60 minutes (without prewarming, 30 minutes). The ambient temperature in the operating room should be at least 21 degrees C for adult patients and at least 24 degrees C for children. Infusions and blood transfusions that are given at rates of >500 ml/h should be warmed first. Perioperatively, the largest possible area of the body surface should be thermally insulated. Emergence from general anesthesia should take place at normal body temperature. Postoperative hypothermia, if present, should be treated by the administration of convective or conductive heat until normothermia is achieved. Shivering can be treated with medications. Conclusion: Inadvertent perioperative hypothermia can adversely affect the outcome of surgery and the patient's postoperative course. It should be actively prevented."],["dc.identifier.isi","000357846600011"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36924"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Aktiv Druck & Verlag Gmbh"],["dc.relation.issn","0170-5334"],["dc.title","S3-Guideline: Avoid unintentional perioperative Hypothermia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]