Richter, Claudia

[["dc.bibliographiccitation.firstpage","371"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","The Journal of Heart and Lung Transplantation"],["dc.bibliographiccitation.lastpage","378"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Wittwer, Thorsten"],["dc.contributor.author","Franke, Ulrich F. W."],["dc.contributor.author","Fehrenbach, A."],["dc.contributor.author","Ochs, Matthias"],["dc.contributor.author","Sandhaus, T."],["dc.contributor.author","Schuette, A."],["dc.contributor.author","Richter, S."],["dc.contributor.author","Dreyer, N."],["dc.contributor.author","Knudsen, L."],["dc.contributor.author","Mueller, T."],["dc.contributor.author","Schubert, H."],["dc.contributor.author","Richter, J."],["dc.contributor.author","Wahlers, T."],["dc.date.accessioned","2018-11-07T11:12:02Z"],["dc.date.available","2018-11-07T11:12:02Z"],["dc.date.issued","2005"],["dc.description.abstract","Background: Ischemia-reperfusion injury accounts for one-third of early deaths after lung transplantation. To expand the limited donor pool, lung retrieval from non-heart-beating donors (NHBD) has been introduced recently. However, because of potentially deleterious effects of warm ischemia on microvascular integrity, use of NHBD lungs is limited by short tolerable time periods before preservation. After intravenous prostanoids are routinely used to ameliorate reperfusion injury, the latest evidence suggests. similar efficacy of inhaled prostacyclin. Therefore, the impact of donor pretreatment with the prostacyclin analogue iloprost on postischemic NHBD lung function and preservation quality was evaluated. Methods: Asystolic pigs (5 per group) were ventilated for 180 minutes of warm ischemia (Group 2). In Group 3, 100 mu g iloprost was aerosolized during the final 30 minutes of ventilation with a novel mobile ultrasonic nebulizer. Lungs were then retrogradely preserved with Perfadex and stored for 3 hours. After left lung transplantation and contralateral lung exclusion, hemodynamics, rO(2)/FiO(2), and dynamic compliance were monitored for 6 hours and compared with sham-operated controls (Group 1). Pulmonary edema was determined both stereologically and by wet-to-dry weight ratio (W/D). Statistics comprised analysis of variance with repeated measures and Mann-Whitney test. Results: Flush preservation pressures, dynamic compliance, inspiratory pressures, and W/D were significantly superior in iloprost-treated lungs, and oxygenation and pulmonary hemodynamics were comparable between groups. Stereology revealed a trend toward lower intraalveolar edema formation in iloprost-treated lungs compared with untreated grafts. Conclusions: Alveolar deposition of Iloprost in NHBD lungs before preservation ameliorates postischemic edema and significantly improves lung compliance. This easily applicable innovative approach, which uses a mobile ultrasonic nebulizer, offers an important strategy for improvement of pulmonary preservation quality and might expand the pool of donor lungs. Copyright (c) 2005 by the International Society for Heart and Lung Transplantation."],["dc.identifier.doi","10.1016/j.healun.2004.02.014"],["dc.identifier.isi","000227922400002"],["dc.identifier.pmid","15812907"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/53571"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.publisher.place","New york"],["dc.relation.conference","23rd Annual Meeting of the International-Society-for-Heart-and-Lung-Transplantation"],["dc.relation.eventlocation","Vienna, AUSTRIA"],["dc.relation.issn","1053-2498"],["dc.title","Donor pretreatment using the aerosolized prostacyclin analogue iloprost optimizes post-ischemic function of non-heart beating donor lungs"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","35"],["dc.bibliographiccitation.lastpage","81"],["dc.bibliographiccitation.seriesnr","338"],["dc.contributor.author","Schwalbe, Harald"],["dc.contributor.author","Carlomagno, Teresa"],["dc.contributor.author","Hennig, Matthias H."],["dc.contributor.author","Junker, Jochen"],["dc.contributor.author","Reif, Bernd"],["dc.contributor.author","Richter, C."],["dc.contributor.author","Griesinger, Christian"],["dc.date.accessioned","2017-09-07T11:46:43Z"],["dc.date.available","2017-09-07T11:46:43Z"],["dc.date.issued","2001"],["dc.identifier.gro","3144329"],["dc.identifier.isi","000170035300002"],["dc.identifier.pmid","11460558"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/1941"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Academic Press"],["dc.publisher.place","San Diego"],["dc.relation.crisseries","Methods in Enzymology"],["dc.relation.isbn","0-12-182239-7"],["dc.relation.ispartof","Nuclear magnetic resonance of biological macromolecules. Part A"],["dc.relation.ispartofseries","Methods in enzymology; 338"],["dc.title","Cross-correlated relaxation for measurement of angles between tensorial interactions"],["dc.type","book_chapter"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","810"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Der Chirurg"],["dc.bibliographiccitation.lastpage","822"],["dc.bibliographiccitation.volume","75"],["dc.contributor.author","Dralle, H."],["dc.contributor.author","Kruse, Eberhard"],["dc.contributor.author","Hamelmann, W. H."],["dc.contributor.author","Grond, S."],["dc.contributor.author","Neumann, H. J."],["dc.contributor.author","Sekulla, C."],["dc.contributor.author","Richter, C."],["dc.contributor.author","Thomusch, O."],["dc.contributor.author","Muhlig, H. P."],["dc.contributor.author","Voss, J."],["dc.contributor.author","Timmermann, W."],["dc.date.accessioned","2018-11-07T10:46:34Z"],["dc.date.available","2018-11-07T10:46:34Z"],["dc.date.issued","2004"],["dc.description.abstract","Since the phoniatrician H. Bauer described the first case of recurrent laryngeal nerve palsy most likely caused by intubation some 45 years ago, several case reports have been published. However, systematic analyses regarding the frequency of recurrent laryngeal nerve palsies due to intubation are scarce, and none of them has used the proper methods to demonstrate clearly that such a mechanism exists. Currently available data justify the assumption that not every recurrent laryngeal nerve palsy following thyroid surgery is due to the operation itself and that the damage caused by intubation, however, may only account for a minority of these cases. The differential diagnosis of postoperative recurrent laryngeal nerve palsy requires the use of specific tools which go beyond simple laryngoscopy and include stroboscopy as well as intra- and extralaryngeal electromyography. A partial palsy of recurrent laryngeal nerve due to intubation would be associated with severe dysphonia or aphonia, not with dyspnea because of the typical intermediate position of the paralyzed vocal folds with a normal electromyographic function of the cricothyroid muscle. The use of these methods to identify the nature of postoperative recurrent laryngeal nerve palsy is recommended in cases of regular intraoperative neuromonitoring but postoperatively impaired function of the vocal cords."],["dc.identifier.doi","10.1007/s00104-004-0857-1"],["dc.identifier.isi","000223729000011"],["dc.identifier.pmid","15146278"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/47776"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1433-0385"],["dc.relation.issn","0009-4722"],["dc.title","Not all vocal cord failure following thyroid surgery is recurrent paresis due to damage during operation. Statement of German Interdisciplinary Study Group on Neuromonitoring of Thyroid Surgery concerning recurring paresis due to intubation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","241"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Biomolecular NMR"],["dc.bibliographiccitation.lastpage","250"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Richter, C."],["dc.contributor.author","Griesinger, Christian"],["dc.contributor.author","Felli, I. C."],["dc.contributor.author","Cole, Trevor"],["dc.contributor.author","Varani, G."],["dc.contributor.author","Schwalbe, Harald"],["dc.date.accessioned","2017-09-07T11:47:26Z"],["dc.date.available","2017-09-07T11:47:26Z"],["dc.date.issued","1999"],["dc.description.abstract","A new experiment, the forward directed quantitative Gamma-HCCH-TOCSY for the measurement of the conformation of the five-membered ribosyl unit in RNA oligonucleotides, is presented. The experiment relies on quantification of cross peak intensities caused by evolution of CH,CH-dipole-dipole cross correlated relaxation in non-evolution periods and the resolution enhancement obtainable in forward directed HCC-TOCSY transfer. Cross correlated relaxation rates are interpreted to reveal the sugar conformation of 22 out of 25 nucleotides in an isotopically labelled 25-mer RNA. The results obtained with this new method are in agreement with the conformational analysis derived from (3)J(H,H) coupling constants."],["dc.identifier.doi","10.1023/A:1008319130714"],["dc.identifier.gro","3144437"],["dc.identifier.isi","000084377900006"],["dc.identifier.pmid","10677827"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/2061"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Kluwer Academic Publ"],["dc.relation.issn","0925-2738"],["dc.title","Determination of sugar conformation in large RNA oligonucleotides from analysis of dipole-dipole cross correlated relaxation by solution NMR spectroscopy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","107"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","The European Physical Journal E"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Richter, C."],["dc.contributor.author","Schmiedeberg, M."],["dc.contributor.author","Stark, Holger"],["dc.date.accessioned","2022-03-01T11:43:40Z"],["dc.date.available","2022-03-01T11:43:40Z"],["dc.date.issued","2011"],["dc.identifier.doi","10.1140/epje/i2011-11107-7"],["dc.identifier.pii","9648"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/102806"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-531"],["dc.relation.eissn","1292-895X"],["dc.relation.issn","1292-8941"],["dc.title","A colloidal model system with tunable disorder: Solid-fluid transition and discontinuities in the limit of zero disorder"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","39"],["dc.bibliographiccitation.journal","Progress in Biophysics and Molecular Biology"],["dc.bibliographiccitation.lastpage","50"],["dc.bibliographiccitation.volume","154"],["dc.contributor.author","Richter, Claudia"],["dc.contributor.author","Brügmann, Tobias"],["dc.date.accessioned","2021-04-14T08:24:33Z"],["dc.date.available","2021-04-14T08:24:33Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1016/j.pbiomolbio.2019.08.013"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81332"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.issn","0079-6107"],["dc.title","No light without the dark: Perspectives and hindrances for translation of cardiac optogenetics"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","750535"],["dc.bibliographiccitation.journal","Frontiers in Physiology"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Diaz-Maue, Laura"],["dc.contributor.author","Steinebach, Janna"],["dc.contributor.author","Richter, Claudia"],["dc.date.accessioned","2022-10-06T13:26:46Z"],["dc.date.available","2022-10-06T13:26:46Z"],["dc.date.issued","2022"],["dc.description.abstract","Much has been reported about optogenetic based cardiac arrhythmia treatment and the corresponding characterization of photostimulation parameters, but still, our capacity to interact with the underlying spatiotemporal excitation patterns relies mainly on electrical and/or pharmacological approaches. However, these well-established treatments have always been an object of somehow heated discussions. Though being acutely life-saving, they often come with potential side-effects leading to a decreased functionality of the complex cardiac system. Recent optogenetic studies showed the feasibility of the usage of photostimulation as a defibrillation method with comparatively high success rates. Although, these studies mainly concentrated on the description as well as on the comparison of single photodefibrillation approaches, such as locally focused light application and global illumination, less effort was spent on the description of excitation patterns during actual photostimulation. In this study, the authors implemented a multi-site photodefibrillation technique in combination with Multi-Lead electrocardiograms (ECGs). The technical connection of real-time heart rhythm measurements and the arrhythmia counteracting light control provides a further step toward automated arrhythmia classification, which can lead to adaptive photodefibrillation methods. In order to show the power effectiveness of the new approach, transgenic murine hearts expressing channelrhodopsin-2\n ex vivo\n were investigated using circumferential micro-LED and ECG arrays. Thus, combining the best of two methods by giving the possibility to illuminate either locally or globally with differing pulse parameters. The optical technique presented here addresses a number of challenges of technical cardiac optogenetics and is discussed in the context of arrhythmic development during photostimulation."],["dc.identifier.doi","10.3389/fphys.2021.750535"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115163"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1664-042X"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Patterned Illumination Techniques in Optogenetics: An Insight Into Decelerating Murine Hearts"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","International Journal of Medical Microbiology"],["dc.bibliographiccitation.volume","296"],["dc.contributor.author","Neumayer, W."],["dc.contributor.author","Truejlzsch, K."],["dc.contributor.author","Richter, S."],["dc.contributor.author","Schmid, A."],["dc.contributor.author","Sauer, Guido"],["dc.contributor.author","Heesemann, Juergen"],["dc.contributor.author","Wilharm, Gottfried"],["dc.date.accessioned","2018-11-07T09:19:42Z"],["dc.date.available","2018-11-07T09:19:42Z"],["dc.date.issued","2006"],["dc.format.extent","145"],["dc.identifier.isi","000241442600272"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28702"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Gmbh, Urban & Fischer Verlag"],["dc.publisher.place","Jena"],["dc.relation.eventlocation","Wurzburg, GERMANY"],["dc.relation.issn","1438-4221"],["dc.title","Cross-talk between type three secretion system and metabolism in Yersinia"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1956"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Journal of the American Chemical Society"],["dc.bibliographiccitation.lastpage","1957"],["dc.bibliographiccitation.volume","121"],["dc.contributor.author","Felli, I. C."],["dc.contributor.author","Richter, C."],["dc.contributor.author","Griesinger, Christian"],["dc.contributor.author","Schwalbe, Harald"],["dc.date.accessioned","2017-09-07T11:47:33Z"],["dc.date.available","2017-09-07T11:47:33Z"],["dc.date.issued","1999"],["dc.identifier.doi","10.1021/ja983434r"],["dc.identifier.gro","3144485"],["dc.identifier.isi","000079143700026"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/2114"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Amer Chemical Soc"],["dc.relation.issn","0002-7863"],["dc.title","Determination of RNA sugar pucker mode from cross-correlated relaxation in solution NMR spectroscopy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Frontiers in Cardiovascular Medicine"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Richter, Claudia"],["dc.contributor.author","Hinkel, Rabea"],["dc.date.accessioned","2021-08-12T07:45:42Z"],["dc.date.available","2021-08-12T07:45:42Z"],["dc.date.issued","2021"],["dc.description.abstract","Diabetes and the often accompanying cardiovascular diseases including cardiomyopathy represent a complex disease, that is reluctant to reveal the molecular mechanisms and underlying cellular responses. Current research projects on diabetic cardiomyopathy are predominantly based on animal models, in which there are not only obvious advantages, such as genetics that can be traced over generations and the directly measurable influence of dietary types, but also not despisable disadvantages. Thus, many studies are built up on transgenic rodent models, which are partly comparable to symptoms in humans due to their genetic alterations, but on the other hand are also under discussion regarding their clinical relevance in the translation of biomedical therapeutic approaches. Furthermore, a focus on transgenic rodent models ignores spontaneously occurring diabetes in larger mammals (such as dogs or pigs), which represent with their anatomical similarity to humans regarding their cardiovascular situation appealing models for testing translational approaches. With this in mind, we aim to shed light on the currently most popular animal models for diabetic cardiomyopathy and, by weighing the advantages and disadvantages, provide decision support for future animal experimental work in the field, hence advancing the biomedical translation of promising approaches into clinical application."],["dc.description.abstract","Diabetes and the often accompanying cardiovascular diseases including cardiomyopathy represent a complex disease, that is reluctant to reveal the molecular mechanisms and underlying cellular responses. Current research projects on diabetic cardiomyopathy are predominantly based on animal models, in which there are not only obvious advantages, such as genetics that can be traced over generations and the directly measurable influence of dietary types, but also not despisable disadvantages. Thus, many studies are built up on transgenic rodent models, which are partly comparable to symptoms in humans due to their genetic alterations, but on the other hand are also under discussion regarding their clinical relevance in the translation of biomedical therapeutic approaches. Furthermore, a focus on transgenic rodent models ignores spontaneously occurring diabetes in larger mammals (such as dogs or pigs), which represent with their anatomical similarity to humans regarding their cardiovascular situation appealing models for testing translational approaches. With this in mind, we aim to shed light on the currently most popular animal models for diabetic cardiomyopathy and, by weighing the advantages and disadvantages, provide decision support for future animal experimental work in the field, hence advancing the biomedical translation of promising approaches into clinical application."],["dc.identifier.doi","10.3389/fcvm.2021.703355"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/88532"],["dc.notes.intern","DOI Import GROB-448"],["dc.relation.eissn","2297-055X"],["dc.title","Research('s) Sweet Hearts: Experimental Biomedical Models of Diabetic Cardiomyopathy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]