Anderson-Schmidt, Heike

[["dc.bibliographiccitation.firstpage","96"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","American Journal of Medical Genetics Part B Neuropsychiatric Genetics"],["dc.bibliographiccitation.lastpage","121"],["dc.bibliographiccitation.volume","162B"],["dc.contributor.author","Anderson-Schmidt, Heike"],["dc.contributor.author","Beltcheva, Olga"],["dc.contributor.author","Brandon, Mariko D."],["dc.contributor.author","Byrne, Enda M."],["dc.contributor.author","Diehl, Eric J."],["dc.contributor.author","Duncan, Laramie"],["dc.contributor.author","Gonzalez, Suzanne D."],["dc.contributor.author","Hannon, Eilis"],["dc.contributor.author","Kantojarvi, Katri"],["dc.contributor.author","Karagiannidis, Iordanis"],["dc.contributor.author","Kos, Mark Z."],["dc.contributor.author","Kotyuk, Eszter"],["dc.contributor.author","Laufer, Benjamin I."],["dc.contributor.author","Mantha, Katarzyna"],["dc.contributor.author","McGregor, Nathaniel W."],["dc.contributor.author","Meier, Sandra"],["dc.contributor.author","Nieratschker, Vanessa"],["dc.contributor.author","Spiers, Helen"],["dc.contributor.author","Squassina, Alessio"],["dc.contributor.author","Thakur, Geeta A."],["dc.contributor.author","Tiwari, Yash"],["dc.contributor.author","Viswanath, Biju"],["dc.contributor.author","Way, Michael J."],["dc.contributor.author","Wong, Cybele C. P."],["dc.contributor.author","O'Shea, Anne"],["dc.contributor.author","DeLisi, Lynn E."],["dc.date.accessioned","2018-11-07T09:27:46Z"],["dc.date.available","2018-11-07T09:27:46Z"],["dc.date.issued","2013"],["dc.description.abstract","The XXth World Congress of Psychiatric Genetics (WCPG), sponsored by The International Society of Psychiatric Genetics (ISPG) took place in Hamburg, Germany on October 1418, 2012. Approximately 600 participants gathered to discuss the latest findings in this rapidly advancing field. The following report was written by student travel awardees. Each was assigned sessions as rapporteurs. This manuscript represents topics covered in most, but not all, oral presentations during the conference, and some of the major notable new findings reported at this 2012 WCPG. (c) 2013 Wiley Periodicals, Inc."],["dc.identifier.doi","10.1002/ajmg.b.32132"],["dc.identifier.isi","000315330800002"],["dc.identifier.pmid","23341144"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30615"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1552-485X"],["dc.relation.issn","1552-4841"],["dc.title","Selected rapporteur summaries from the XX world congress of psychiatric genetics, Hamburg, Germany, october 1418, 2012"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","36"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Schizophrenia Research"],["dc.bibliographiccitation.lastpage","42"],["dc.bibliographiccitation.volume","159"],["dc.contributor.author","Scanlon, Cathy"],["dc.contributor.author","Anderson-Schmidt, Heike"],["dc.contributor.author","Kilmartin, Liam"],["dc.contributor.author","McInerney, Shane"],["dc.contributor.author","Kenney, Joanne"],["dc.contributor.author","McFarland, John"],["dc.contributor.author","Waldron, Mairead"],["dc.contributor.author","Ambati, Srinath"],["dc.contributor.author","Fullard, Anna"],["dc.contributor.author","Logan, Sam"],["dc.contributor.author","Hallahan, Brian"],["dc.contributor.author","Barker, Gareth J."],["dc.contributor.author","Elliott, Mark A."],["dc.contributor.author","McCarthy, Peter"],["dc.contributor.author","Cannon, Dara M."],["dc.contributor.author","McDonald, Colm"],["dc.date.accessioned","2018-11-07T09:34:38Z"],["dc.date.available","2018-11-07T09:34:38Z"],["dc.date.issued","2014"],["dc.description.abstract","First episode psychosis (FEP) has been associated with structural brain changes, largely identified by volumetric analyses. Advances in neuroimaging processing have made it possible to measure geometric properties that may identify subtle structural changes not appreciated by a measure of volume alone. In this study we adopt complementary methods of assessing the structural integrity of grey matter in FEP patients and assess whether these relate to patient clinical and functional outcome at 3 year follow-up. 1.5 Tesla T1-weighted Magnetic Resonance (MR) images were acquired for 46 patients experiencing their first episode of psychosis and 46 healthy controls. Cerebral cortical thickness and local gyrification index (LGI) were investigated using FreeSurfer software. Volume and shape of the hippocampus, caudate and lateral ventricles were assessed using manual tracing and spherical harmonics applied for shape description. A cluster of cortical thinning was identified in FEP compared to controls; this was located in the right superior temporal gyrus, sulcus, extended into the middle temporal gyrus (lateral temporal cortex - LTC). Bilateral caudate volumes were significantly lower in FEP relative to controls and the right caudate also displayed regions of shape deflation in the FEP group. No significant structural abnormalities were identified in cortical LGI or hippocampal or lateral ventricle volume/shape. Neither LTC nor caudate abnormalities were related to change in symptom severity or global functioning 3 years later. LTC and caudate abnormalities are present at the first episode of psychosis but do not appear to directly affect clinical or functional outcome. (C) 2014 Elsevier B. V. All rights reserved."],["dc.description.sponsorship","Health Research Board [HRA_POR/2011/100]"],["dc.identifier.doi","10.1016/j.schres.2014.07.030"],["dc.identifier.isi","000343107400007"],["dc.identifier.pmid","25124520"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32217"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","1573-2509"],["dc.relation.issn","0920-9964"],["dc.title","Cortical thinning and caudate abnormalities in first episode psychosis and their association with clinical outcome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S968"],["dc.bibliographiccitation.journal","European Neuropsychopharmacology"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Gade, Katrin"],["dc.contributor.author","Papiol, Sergi"],["dc.contributor.author","Heilbronner, Urs"],["dc.contributor.author","Budde, Monika"],["dc.contributor.author","Adorjan, Kristina"],["dc.contributor.author","Anderson-Schmidt, Heike"],["dc.contributor.author","Kalman, Janos"],["dc.contributor.author","Aldinger, Fanny"],["dc.contributor.author","Andlauer, Till F.M."],["dc.contributor.author","Schulze, Thomas"],["dc.date.accessioned","2020-12-10T14:23:55Z"],["dc.date.available","2020-12-10T14:23:55Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.euroneuro.2017.08.333"],["dc.identifier.issn","0924-977X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72075"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","THE IMPACT OF BIPOLAR AND SCHIZOPHRENIA POLYGENIC RISK SCORES ON FAMILIAL FEATURES OF BIPOLAR DISORDER"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S951"],["dc.bibliographiccitation.journal","European Neuropsychopharmacology"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Adorjan, Kristina"],["dc.contributor.author","Papiol, Sergi"],["dc.contributor.author","Gade, Katrin"],["dc.contributor.author","Malzahn, Dörthe"],["dc.contributor.author","Sherva, Richard"],["dc.contributor.author","Budde, Monika"],["dc.contributor.author","Aldinger, Fanny"],["dc.contributor.author","Kalman, Janos"],["dc.contributor.author","Heilbronner, Urs"],["dc.contributor.author","Anderson-Schmidt, Heike"],["dc.contributor.author","Pogarell, Oliver"],["dc.contributor.author","Falkai, Peter"],["dc.contributor.author","Gelernter, Joel"],["dc.contributor.author","Schulze, Thomas"],["dc.date.accessioned","2020-12-10T14:23:55Z"],["dc.date.available","2020-12-10T14:23:55Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1016/j.euroneuro.2017.08.302"],["dc.identifier.issn","0924-977X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72073"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","POLYGENIC RISK BURDEN AND CANNABIS USE COMORBIDITY IN PATIENTS WITH SCHIZOPHRENIA AND BIPOLAR DISORDER"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","115"],["dc.bibliographiccitation.journal","Comprehensive Psychiatry"],["dc.bibliographiccitation.lastpage","121"],["dc.bibliographiccitation.volume","61"],["dc.contributor.author","Lang, F. U."],["dc.contributor.author","Walther, Stefanie"],["dc.contributor.author","Stegmayer, Katharina"],["dc.contributor.author","Anderson-Schmidt, Heike"],["dc.contributor.author","Schulze, Thomas G."],["dc.contributor.author","Becker, T."],["dc.contributor.author","Jaeger, Markus"],["dc.date.accessioned","2018-11-07T09:54:08Z"],["dc.date.available","2018-11-07T09:54:08Z"],["dc.date.issued","2015"],["dc.description.abstract","Background: Schizophrenia is a heterogeneous disorder. Over the years, different approaches have been proposed to approach this heterogeneity by categorizing symptom patterns. The study aimed to compare positive/negative and system-specific approaches to subtyping. Methods: We used the Positive and Negative Syndrome Scale (PANSS) and Bern Psychopathology Scale (BPS), which consists of subscales for three domains (language, affect and motor behavior) that are hypothesized to be related to specific brain circuits, to assess cross-sectional psychopathological characteristics in a sample of 100 inpatients with schizophrenia spectrum disorders. We then categorized participants into positive/negative and system-specific subgroups to allow comparisons of the two approaches. Results: The analyses revealed correlations between the PANSS positive subscore and the BPS affective subscore (r =.446, p <.001) and between the PANSS negative subscore and the BPS motor behavior subscore (r =.227, p =.023). As regards the positive and negative subtype, more participants were classified as positive in the language-dominant subtype (30.3%) and affect-dominant subtype (30.3%), whereas more were classified as negative in the motor behavior-dominant subtype (44.4%). However, most patients met the criteria for the mixed subtype. Conclusions: The results suggest that the positive/negative and system-specific approaches can be regarded as complementary. Future studies should examine both approaches in a longitudinal assessment of psychopathological symptoms and link them with qualitative-phenomenological approaches. (C) 2015 Elsevier Inc. All rights reserved."],["dc.identifier.doi","10.1016/j.comppsych.2015.05.014"],["dc.identifier.isi","000357908800016"],["dc.identifier.pmid","26104431"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36473"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","W B Saunders Co-elsevier Inc"],["dc.relation.issn","1532-8384"],["dc.relation.issn","0010-440X"],["dc.title","Subtyping schizophrenia: A comparison of positive/negative and system-specific approaches"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","American Journal of Medical Genetics Part B: Neuropsychiatric Genetics"],["dc.bibliographiccitation.volume","180"],["dc.contributor.author","Budde, Monika"],["dc.contributor.author","Anderson‐Schmidt, Heike"],["dc.contributor.author","Gade, Katrin"],["dc.contributor.author","Reich‐Erkelenz, Daniela"],["dc.contributor.author","Adorjan, Kristina"],["dc.contributor.author","Kalman, Janos L."],["dc.contributor.author","Senner, Fanny"],["dc.contributor.author","Papiol, Sergi"],["dc.contributor.author","Andlauer, Till F. M."],["dc.contributor.author","Comes, Ashley L."],["dc.contributor.author","Heilbronner, Urs"],["dc.date.accessioned","2021-12-08T12:29:30Z"],["dc.date.available","2021-12-08T12:29:30Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1002/ajmg.b.32717"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/96099"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-476"],["dc.relation.eissn","1552-485X"],["dc.relation.issn","1552-4841"],["dc.title","Cover Image, Volume 180B, Number 2, March 2019"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S395"],["dc.bibliographiccitation.journal","European Neuropsychopharmacology"],["dc.bibliographiccitation.lastpage","S396"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Anderson-Schmidt, Heike"],["dc.contributor.author","Papiol, Sergi"],["dc.contributor.author","Andlauer, Till F.M."],["dc.contributor.author","Heilbronner, Urs"],["dc.contributor.author","Budde, Monika"],["dc.contributor.author","Kalman, Janos"],["dc.contributor.author","Degenhardt, Franziska"],["dc.contributor.author","Nöthen, Markus"],["dc.contributor.author","Strohmaier, Jana"],["dc.contributor.author","Frank, Josef"],["dc.contributor.author","Witt, Stephanie"],["dc.contributor.author","Müller-Myhsok, Bertram"],["dc.contributor.author","Falkai, Peter"],["dc.contributor.author","Rietschel, Marcella"],["dc.contributor.author","Schulze, Thomas G."],["dc.date.accessioned","2020-12-10T14:23:51Z"],["dc.date.available","2020-12-10T14:23:51Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1016/j.euroneuro.2016.09.433"],["dc.identifier.issn","0924-977X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72065"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Using Polygenic Scores Based on Schneiderian First Rank Symptoms To Characterize Disease Trajectories In Severe Mental Illnesses"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","456"],["dc.bibliographiccitation.journal","European Neuropsychopharmacology"],["dc.bibliographiccitation.lastpage","457"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Heilbronner, Urs"],["dc.contributor.author","Jain, Gaurav"],["dc.contributor.author","Kaurani, Lalit"],["dc.contributor.author","Kondofersky, Ivan"],["dc.contributor.author","Budde, Monika"],["dc.contributor.author","Gade, Katrin"],["dc.contributor.author","Kalman, Janos"],["dc.contributor.author","Adorjan, Kristina"],["dc.contributor.author","Aldinger, Fanny"],["dc.contributor.author","Anderson-Schmidt, Heike"],["dc.contributor.author","Mueller, Nikola"],["dc.contributor.author","Theis, Fabian J."],["dc.contributor.author","Falkai, Peter"],["dc.contributor.author","Fischer, André"],["dc.contributor.author","Schulze, Thomas G."],["dc.date.accessioned","2018-01-09T14:32:55Z"],["dc.date.available","2018-01-09T14:32:55Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1016/j.euroneuro.2016.09.527"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/11601"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.title","The Role Of Micrornas In The Course Of Severe Mental Disorders"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","944"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Neuropsychopharmacology"],["dc.bibliographiccitation.lastpage","954"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Holleran, Laurena"],["dc.contributor.author","Ahmed, Mohamed"],["dc.contributor.author","Anderson-Schmidt, Heike"],["dc.contributor.author","McFarland, John"],["dc.contributor.author","Emsell, Louise"],["dc.contributor.author","Leemanss, Alexander"],["dc.contributor.author","Scanlon, Cathy"],["dc.contributor.author","Dockery, Peter"],["dc.contributor.author","McCarthy, Peter"],["dc.contributor.author","Barker, Gareth J."],["dc.contributor.author","McDonald, Colm"],["dc.contributor.author","Cannon, Dara M."],["dc.date.accessioned","2018-11-07T09:43:28Z"],["dc.date.available","2018-11-07T09:43:28Z"],["dc.date.issued","2014"],["dc.description.abstract","Diffusion MRI investigations in schizophrenia provide evidence of abnormal white matter (WM) microstructural organization as indicated by reduced fractional anisotropy (FA) primarily in interhemispheric, left frontal and temporal WM. Using tract-based spatial statistics (TBSS), we examined diffusion parameters in a sample of patients with severe chronic schizophrenia. Diffusion MRI data were acquired on 19 patients with chronic severe schizophrenia and 19 age- and gender-matched healthy controls using a 64 gradient direction sequence, (b = 1300 s/mm(2)) collected on a Siemens 1.5T MRI scanner. Diagnosis of schizophrenia was determined by Diagnostic and Statistical Manual for Mental Disorders 4th Edition (DSM-IV) Structured Clinical Interview for DSM disorder (SCID). Patients were treatment resistance, having failed to respond to at least two antipsychotic medications, and had prolonged periods of moderate to severe positive or negative symptoms. Analysis of diffusion parameters was carried out using TBSS. Individuals with chronic severe schizophrenia had significantly reduced FA with corresponding increased radial diffusivity in the genu, body, and splenium of the corpus callosum, the right posterior limb of the internal capsule, right external capsule, and the right temporal inferior longitudinal fasciculus. There were no voxels of significantly increased FA in patients compared with controls. A decrease in splenium FA was shown to be related to a longer illness duration. We detected widespread abnormal diffusivity properties in the callosal and temporal lobe WM regions in individuals with severe chronic schizophrenia who have not previously been exposed to clozapine. These deficits can be driven by a number of factors that are indistinguishable using in vivo diffusion-weighted imaging, but may be related to reduced axonal number or packing density, abnormal glial cell arrangement or function, and reduced myelin."],["dc.identifier.doi","10.1038/npp.2013.294"],["dc.identifier.isi","000331345300017"],["dc.identifier.pmid","24150571"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34192"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Nature Publishing Group"],["dc.relation.issn","1740-634X"],["dc.relation.issn","0893-133X"],["dc.title","Altered Interhemispheric and Temporal Lobe White Matter Microstructural Organization in Severe Chronic Schizophrenia"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","121"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Zeitschrift für Sexualforschung"],["dc.bibliographiccitation.lastpage","131"],["dc.bibliographiccitation.volume","28"],["dc.contributor.author","Signerski-Krieger, Jörg"],["dc.contributor.author","Annen, Saskia"],["dc.contributor.author","Anderson-Schmidt, Heike"],["dc.contributor.author","Plitt, Heike"],["dc.contributor.author","Wiltfang, Jens"],["dc.date.accessioned","2017-09-07T11:44:29Z"],["dc.date.available","2017-09-07T11:44:29Z"],["dc.date.issued","2015"],["dc.description.abstract","Zum Häufigkeit sexueller Probleme bei Patientinnen und Patienten mit einer Borderline-Persönlichkeitsstörungen (BPS) liegen bisher nur wenige Forschungsergebnisse vor. Ziel der vorliegenden Studie war es, Sexualität und Lebenszufriedenheit bei BPS-Patientinnen und Patienten im Vergleich mit einer Kontrollgruppe zu untersuchen. Dazu wurde ein Fragebogen mit dem die Skalen „Allgemeine Zufriedenheit“, „Sexuelle Zufriedenheit“, „Ängste/Depressionen“ und „Sexuelle Probleme“ entwickelt. Dieser wurde dann an einer klinischen Population von Patientinnen und Patienten mit einer Borderline-Persönlichkeitsstörungen (n = 52) sowie an einer nicht-klinischen Stichprobe (n = 293) erhoben. Der Vergleich zwischen BPS-Patientinnen und Patienten und der Kontrollgruppe zeigt Unterschiede in allen vier Skalen sowie Zusammenhänge zwischen den einzelnen Skalen. Auf Grundlage der Ergebnisse wird die störungsspezifische Symptomatik der sexuellen Probleme von BPS-Patientinnen und Patienten diskutiert."],["dc.identifier.doi","10.1055/s-0035-1553075"],["dc.identifier.gro","3151683"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8501"],["dc.language.iso","de"],["dc.notes.status","final"],["dc.notes.submitter","chake"],["dc.relation.issn","0932-8114"],["dc.title","Sexuelle Probleme, sexuelle Zufriedenheit und Lebenszufriedenheit bei Patientinnen und Patienten mit einer Borderline-Persönlichkeitsstörung"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]