Tietze, Lutz Friedjan

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[["dc.bibliographiccitation.firstpage","3286"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Chemistry - A European Journal"],["dc.bibliographiccitation.lastpage","3291"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Tietze, Lutz Friedjan"],["dc.contributor.author","Hungerland, Tim"],["dc.contributor.author","Duefert, Alexander"],["dc.contributor.author","Objartel, Ina"],["dc.contributor.author","Stalke, Dietmar"],["dc.date.accessioned","2018-11-07T09:12:39Z"],["dc.date.available","2018-11-07T09:12:39Z"],["dc.date.issued","2012"],["dc.description.abstract","Helical tetrasubstituted alkenes (7) were obtained in a highly efficient way through a palladium-catalyzed domino-carbopalladation/CH-activation reaction of propargylic alcohols 6 in good to excellent yields. Electron-withdrawing- and electron-donating substituents can be introduced onto the upper and lower aromatic rings. The substrates (6) for the domino process were synthesized by addition of the lithiated alkyne (20) to various aldehydes (19); moreover, the substrates were accessible enantioselectively (in 95?% ee) by reduction of the corresponding ketone using the Noyori procedure."],["dc.identifier.doi","10.1002/chem.201103209"],["dc.identifier.isi","000300972500025"],["dc.identifier.pmid","22259072"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/26989"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-v C H Verlag Gmbh"],["dc.relation.issn","0947-6539"],["dc.title","Synthesis of Tetrasubstituted Alkenes through a Palladium-Catalyzed Domino Carbopalladation/C-H-Activation Reaction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2007"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Organic Letters"],["dc.bibliographiccitation.lastpage","2010"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Khan, Taukeer A."],["dc.contributor.author","Fornefeld, Torsten"],["dc.contributor.author","Hübner, Dennis"],["dc.contributor.author","Vana, Philipp"],["dc.contributor.author","Tietze, Lutz F."],["dc.date.accessioned","2018-08-14T15:26:49Z"],["dc.date.available","2018-08-14T15:26:49Z"],["dc.date.issued","2018"],["dc.description.abstract","A palladium-catalyzed 4-fold domino reaction consisting of two carbopalladation reactions and two C–H activation reactions, followed by the introduction of an acrylate moiety, led to the tetra-substituted helical alkene A2, using the dialkyne A3 as a substrate. The alkene was copolymerized with butyl acrylate by using the reversible addition–fragmentation chain transfer polymerization (RAFT) to give the desired polymeric switch A1."],["dc.identifier.doi","10.1021/acs.orglett.8b00553"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15296"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.title","Palladium-Catalyzed 4-Fold Domino Reaction for the Synthesis of a Polymeric Double Switch"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1296"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Chemistry - A European Journal"],["dc.bibliographiccitation.lastpage","1302"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Tietze, Lutz Friedjan"],["dc.contributor.author","Griesbach, U."],["dc.contributor.author","Schuberth, I."],["dc.contributor.author","Bothe, U."],["dc.contributor.author","Marra, A."],["dc.contributor.author","Dondoni, A."],["dc.date.accessioned","2018-11-07T10:39:58Z"],["dc.date.available","2018-11-07T10:39:58Z"],["dc.date.issued","2003"],["dc.description.abstract","The synthesis of the novel unprotected carboranyl C-glycosides 2 and 20 24 starting from ethynyl C-glycosides 1, 5-8, 10, and 13 is described. The new compounds are highly water-soluble and display only a very low cytotoxicity, which makes them promising candidates for use in boron neutron capture therapy for the treatment of cancer."],["dc.identifier.doi","10.1002/chem.200390148"],["dc.identifier.isi","000181817400005"],["dc.identifier.pmid","12645018"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/46188"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-v C H Verlag Gmbh"],["dc.relation.issn","0947-6539"],["dc.title","Novel carboranyl C-glycosides for the treatment of cancer by boron neutron capture therapy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","517"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Antimicrobial Agents and Chemotherapy"],["dc.bibliographiccitation.lastpage","521"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Bajohr, Lara Liv"],["dc.contributor.author","Ma, Ling"],["dc.contributor.author","Platte, Christian"],["dc.contributor.author","Liesenfeld, Oliver"],["dc.contributor.author","Tietze, Lutz Friedjan"],["dc.contributor.author","Gross, Uwe"],["dc.contributor.author","Bohne, Wolfgang"],["dc.date.accessioned","2018-11-07T08:47:00Z"],["dc.date.available","2018-11-07T08:47:00Z"],["dc.date.issued","2010"],["dc.description.abstract","1-Hydroxy-2-dodecyl-4(1H) quinolone (HDQ) was recently identified as a Toxoplasma gondii inhibitor. We describe here two novel 1-hydroxyquinolones, which displayed 50% inhibitory concentrations 10- and 5-fold lower than that of HDQ. In a mouse model of acute toxoplasmosis, these two compounds and HDQ reduced the percentages of infected peritoneal cells and decreased the parasite loads in lungs and livers. Compound B showed a tendency toward lowering parasite loads in brains in a mouse model of toxoplasmic encephalitis."],["dc.identifier.doi","10.1128/AAC.01001-09"],["dc.identifier.isi","000272931200069"],["dc.identifier.pmid","19884369"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20837"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Soc Microbiology"],["dc.relation.issn","0066-4804"],["dc.title","In Vitro and In Vivo Activities of 1-Hydroxy-2-Alkyl-4(1H)Quinolone Derivatives against Toxoplasma gondii"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

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