Now showing 1 - 10 of 55
  • 2015Conference Abstract
    [["dc.bibliographiccitation.journal","Oncology Research and Treatment"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Schanz, J."],["dc.contributor.author","Haase, Detlef"],["dc.date.accessioned","2018-11-07T09:50:35Z"],["dc.date.available","2018-11-07T09:50:35Z"],["dc.date.issued","2015"],["dc.format.extent","32"],["dc.identifier.isi","000364268800068"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35736"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.publisher.place","Basel"],["dc.relation.issn","2296-5262"],["dc.relation.issn","2296-5270"],["dc.title","Evolution of chromosome 7 material loss in myeloid malignancies"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2015Journal Article
    [["dc.bibliographiccitation.firstpage","254"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","European Journal Of Haematology"],["dc.bibliographiccitation.lastpage","256"],["dc.bibliographiccitation.volume","95"],["dc.contributor.author","Schanz, Julie"],["dc.contributor.author","Haase, Detlef"],["dc.contributor.author","Steuernagel, Peter"],["dc.contributor.author","Shirneshan, Katayoo"],["dc.contributor.author","Baesecke, Joerg"],["dc.date.accessioned","2018-11-07T09:52:53Z"],["dc.date.available","2018-11-07T09:52:53Z"],["dc.date.issued","2015"],["dc.description.abstract","A 62-yr-old man with two healthy daughters was diagnosed with osteomyelofibrosis. To our surprise, a female XX-karyotype was observed in bone marrow and confirmed in PHA-stimulated T-lymphocytes from peripheral blood. Further molecular genetic investigation revealed a submicroscopic translocation between the short arm of X and Y, which leads to an XX-male genotype based on an unbalanced translocation X;Y. This rare coincidence was further accentuated as the USP9Y gene, suspected to be to be involved in sperm cell production, was absent, but no azoospermia was present. In general, routine cytogenetics may result in findings that need to be further delineated and, as here, lead to a rare observation."],["dc.identifier.doi","10.1111/ejh.12555"],["dc.identifier.isi","000359600500009"],["dc.identifier.pmid","25808090"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36217"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1600-0609"],["dc.relation.issn","0902-4441"],["dc.title","Primary osteomyelofibrosis and an XX-male genotype"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2014Conference Abstract
    [["dc.bibliographiccitation.firstpage","43"],["dc.bibliographiccitation.journal","Oncology Research and Treatment"],["dc.bibliographiccitation.lastpage","44"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Kaempfe, Dietrich"],["dc.contributor.author","Machherndl-Spandl, Sigrid"],["dc.contributor.author","Suessner, Susanne"],["dc.contributor.author","Koziolek, Michael Johann"],["dc.contributor.author","Haase, Detlef"],["dc.contributor.author","Schanz, J."],["dc.date.accessioned","2018-11-07T09:34:10Z"],["dc.date.available","2018-11-07T09:34:10Z"],["dc.date.issued","2014"],["dc.identifier.isi","000343816900097"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32120"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.publisher.place","Basel"],["dc.relation.issn","2296-5262"],["dc.relation.issn","2296-5270"],["dc.title","Significance of Y-chromosome loss in MDS"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2016Conference Abstract
    [["dc.bibliographiccitation.journal","Haematologica"],["dc.bibliographiccitation.volume","101"],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Dierks, Sascha"],["dc.contributor.author","Glass, Bertram"],["dc.contributor.author","Stuhlmann, Reingard"],["dc.contributor.author","Baesecke, Joerg"],["dc.contributor.author","Sievers, B."],["dc.contributor.author","Simon-Becker, S."],["dc.contributor.author","Flach, J."],["dc.contributor.author","Martin, R."],["dc.contributor.author","Bacher, Ulrike"],["dc.contributor.author","Haase, Detlef"],["dc.date.accessioned","2018-11-07T10:13:03Z"],["dc.date.available","2018-11-07T10:13:03Z"],["dc.date.issued","2016"],["dc.format.extent","495"],["dc.identifier.isi","000379484601582"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40359"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Ferrata Storti Foundation"],["dc.publisher.place","Pavia"],["dc.relation.conference","21st Congress of the European-Hematology-Association"],["dc.relation.eventlocation","Copenhagen, DENMARK"],["dc.relation.issn","0390-6078"],["dc.title","SPATIAL INTERACTION OF CYTOGENETIC AND MOLECULAR MUTATIONS IN MYELODYSPLASTIC SYNDROMES"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2013Journal Article
    [["dc.bibliographiccitation.firstpage","900"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Leukemia Research"],["dc.bibliographiccitation.lastpage","906"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Jung, Klaus"],["dc.contributor.author","Schanz, Julie"],["dc.contributor.author","Götze, Katharina S."],["dc.contributor.author","Müller-Thomas, Catharina"],["dc.contributor.author","Platzbecker, Uwe"],["dc.contributor.author","Germing, Ulrich"],["dc.contributor.author","Brümmendorf, Tim H."],["dc.contributor.author","Bug, Gesine"],["dc.contributor.author","Ottmann, Oliver G."],["dc.contributor.author","Giagounidis, Aristoteles A. N."],["dc.contributor.author","Stadler, Michael"],["dc.contributor.author","Hofmann, Wolf-Karsten"],["dc.contributor.author","Schafhausen, Philippe"],["dc.contributor.author","Lübbert, Michael"],["dc.contributor.author","Schlenk, Richard F."],["dc.contributor.author","Blau, Igor W."],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Pfeiffer, Sebastian"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Metz, Michael"],["dc.contributor.author","Detken, Sven"],["dc.contributor.author","Seraphin, Jörg"],["dc.contributor.author","Jentsch-Ullrich, Kathleen"],["dc.contributor.author","Böhme, Angelika"],["dc.contributor.author","Schmidt, Burkhard C."],["dc.contributor.author","Trümper, Lorenz"],["dc.contributor.author","Haase, Detlef"],["dc.date.accessioned","2018-11-07T09:22:10Z"],["dc.date.available","2018-11-07T09:22:10Z"],["dc.date.issued","2013"],["dc.description.abstract","The gold standard of cytogenetic analysis in myelodysplastic syndromes (MDS) is conventional chromosome banding (CCB) analysis of bone marrow (BM) metaphases. Most aberrations can also be detected by fluorescence-in situ-hybridization (FISH). For this prospective multicenter German diagnostic study (www.clinicaltrials.gov: #NCT01355913) 360 patients, as yet, were followed up to 3 years by sequential FISH analyses of immunomagnetically enriched CD34+ peripheral blood (PB) cells using comprehensive FISH probe panels, resulting in a total number of 19,516 FISH analyses. We demonstrate that CD34+ PB FISH correlates significantly with CCB analysis and represents a feasible method for a reliable non-invasive cytogenetic monitoring from PB. (C) 2013 Elsevier Ltd. All rights reserved."],["dc.description.sponsorship","Celgene(R) Germany"],["dc.identifier.doi","10.1016/j.leukres.2013.03.019"],["dc.identifier.isi","000321111900012"],["dc.identifier.pmid","23623559"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29278"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.notes.submitter","Najko"],["dc.relation.issn","0145-2126"],["dc.title","Molecular cytogenetic monitoring from CD34+peripheral blood cells in myelodysplastic syndromes: First results from a prospective multicenter German diagnostic study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]
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  • 2016Conference Abstract
    [["dc.bibliographiccitation.journal","Oncology Research and Treatment"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Germing, U."],["dc.contributor.author","Schuler, E."],["dc.contributor.author","Schulz, Xenia"],["dc.contributor.author","Platzbecker, Uwe"],["dc.contributor.author","Nolte, F."],["dc.contributor.author","Hofmann, W-K"],["dc.contributor.author","Giagounidis, Aristoteles A. N."],["dc.contributor.author","Goetze, K."],["dc.contributor.author","Luebbert, Michael"],["dc.contributor.author","Schlenk, Richard F."],["dc.contributor.author","Schanz, J."],["dc.contributor.author","Bacher, Ulrike"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Ganser, Arnold"],["dc.contributor.author","Letsch, Anne"],["dc.contributor.author","Schafhausen, Philippe"],["dc.contributor.author","Bug, G."],["dc.contributor.author","Bruemmendorf, Tim Hendrik"],["dc.contributor.author","Haas, Rainer"],["dc.contributor.author","Truemper, Lorenz H."],["dc.contributor.author","Haase, Detlef"],["dc.date.accessioned","2018-11-07T10:07:38Z"],["dc.date.available","2018-11-07T10:07:38Z"],["dc.date.issued","2016"],["dc.format.extent","235"],["dc.identifier.isi","000385691300581"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39317"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.publisher.place","Basel"],["dc.relation.issn","2296-5262"],["dc.relation.issn","2296-5270"],["dc.title","Cytogenetic monitoring from peripheral blood in patients with myelodysplastic syndrome: First results from the German LEMON-5 trial"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2014Conference Abstract
    [["dc.bibliographiccitation.firstpage","235"],["dc.bibliographiccitation.journal","Oncology Research and Treatment"],["dc.bibliographiccitation.lastpage","236"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Platzbecker, Uwe"],["dc.contributor.author","Mueller-Thomas, Catharina"],["dc.contributor.author","Goetze, K."],["dc.contributor.author","Germing, U."],["dc.contributor.author","Bruemmendorf, Tim Hendrik"],["dc.contributor.author","Nolte, F."],["dc.contributor.author","Hofmann, W-K"],["dc.contributor.author","Giagounidis, Aristoteles A. N."],["dc.contributor.author","Luebbert, Michael"],["dc.contributor.author","Greenberg, Peter L."],["dc.contributor.author","Bennett, John M."],["dc.contributor.author","Sole, Francesco"],["dc.contributor.author","Mallo, Mar"],["dc.contributor.author","Slovak, Marilyn L."],["dc.contributor.author","Ohyashiki, Kazuma"],["dc.contributor.author","Le Beau, Michelle M."],["dc.contributor.author","Tuechler, Heinz"],["dc.contributor.author","Pfeilstoecker, Michael"],["dc.contributor.author","Noesslinger, T."],["dc.contributor.author","Hildebrandt, B."],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Aul, Carlo"],["dc.contributor.author","Stauder, Reinhard"],["dc.contributor.author","Sperr, Wolfgang R."],["dc.contributor.author","Valent, Peter"],["dc.contributor.author","Fonatsch, Christa"],["dc.contributor.author","Truemper, Lorenz H."],["dc.contributor.author","Haase, Detlef"],["dc.contributor.author","Schanz, J."],["dc.date.accessioned","2018-11-07T09:34:15Z"],["dc.date.available","2018-11-07T09:34:15Z"],["dc.date.issued","2014"],["dc.identifier.isi","000343816900574"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32137"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.publisher.place","Basel"],["dc.relation.issn","2296-5262"],["dc.relation.issn","2296-5270"],["dc.title","Is IPSS/IPSS-R cytogenetic classification possible from peripheral blood in MDS patients? Comparative results from a prospective German diagnostic study with the data set of an international collaboration"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2013Conference Abstract
    [["dc.bibliographiccitation.journal","Onkologie"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Schanz, J."],["dc.contributor.author","Goetze, K."],["dc.contributor.author","Mueller-Thomas, Catharina"],["dc.contributor.author","Platzbecker, Uwe"],["dc.contributor.author","Germing, U."],["dc.contributor.author","Bruemmendorf, Tim Hendrik"],["dc.contributor.author","Bug, G."],["dc.contributor.author","Giagounidis, Aristoteles A. N."],["dc.contributor.author","Nolte, F."],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Metz, M."],["dc.contributor.author","Truemper, Lorenz H."],["dc.contributor.author","Haase, Detlef"],["dc.date.accessioned","2018-11-07T09:19:07Z"],["dc.date.available","2018-11-07T09:19:07Z"],["dc.date.issued","2013"],["dc.format.extent","230"],["dc.identifier.isi","000326360900578"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28561"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.publisher.place","Basel"],["dc.relation.issn","1423-0240"],["dc.relation.issn","0378-584X"],["dc.title","Karyotype evolution in MDS patients detected by CD34+PB - FISH first results of the ongoing prospective multi-center German diagnostic study"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2010Conference Abstract
    [["dc.bibliographiccitation.issue","21"],["dc.bibliographiccitation.journal","Blood"],["dc.bibliographiccitation.volume","116"],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Sole, Francesc"],["dc.contributor.author","Mallo, Mar"],["dc.contributor.author","Cervera, Jose"],["dc.contributor.author","Luno, Elisa"],["dc.contributor.author","Hildebrandt, Barbara"],["dc.contributor.author","Steidl, Christian"],["dc.contributor.author","Fonatsch, Christa"],["dc.contributor.author","Pfeilstoecker, Michael"],["dc.contributor.author","Noesslinger, Thomas"],["dc.contributor.author","Valent, Peter"],["dc.contributor.author","Giagounidis, Aristoteles A. N."],["dc.contributor.author","Aul, Carlo"],["dc.contributor.author","Luebbert, Michael"],["dc.contributor.author","Stauder, Reinhard"],["dc.contributor.author","Krieger, Otto"],["dc.contributor.author","Le Beau, Michelle M."],["dc.contributor.author","Bennett, John M."],["dc.contributor.author","Greenberg, Peter L."],["dc.contributor.author","Germing, Ulrich"],["dc.contributor.author","Haase, Detlef"],["dc.contributor.author","Schanz, Julie"],["dc.date.accessioned","2018-11-07T08:36:47Z"],["dc.date.available","2018-11-07T08:36:47Z"],["dc.date.issued","2010"],["dc.format.extent","1634"],["dc.identifier.isi","000289662204428"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18389"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Soc Hematology"],["dc.publisher.place","Washington"],["dc.relation.conference","52nd Annual Meeting of the American-Society-of-Hematology (ASH)"],["dc.relation.eventlocation","Orlando, FL"],["dc.relation.issn","0006-4971"],["dc.title","Loss of the Y Chromosome in MDS - Age-Related Phenomenon or Clonal Abnormality?"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2010Journal Article
    [["dc.bibliographiccitation.firstpage","1296"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Leukemia Research"],["dc.bibliographiccitation.lastpage","1301"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Schanz, Julie"],["dc.contributor.author","Jung, Klaus"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Schulte, Kristina"],["dc.contributor.author","Schuetze, Claudia"],["dc.contributor.author","Steffens, Rainer"],["dc.contributor.author","Truemper, Lorenz H."],["dc.contributor.author","Haase, Detlef"],["dc.date.accessioned","2018-11-07T08:38:40Z"],["dc.date.available","2018-11-07T08:38:40Z"],["dc.date.issued","2010"],["dc.description.abstract","In myelodysplastic syndromes (MDS) chromosomal anomalies can be identified in 50-80% of patients. They have a diagnostic and prognostic impact and are increasingly considered for therapeutic decisions. Cytomorphology and cytogenetic analyses of bone marrow (bm) cells define the goldstandard to diagnose MDS patients and to document treatment response. We present a novel method using peripheral blood (pb) for frequent cytogenetic monitoring: after immunomagnetic cell separation circulating CD34+ cells were analysed by fluorescence in situ hybridization (FISH). We compared FISH analyses of enriched and non-enriched pb and bm cells with conventional chromosome banding analyses of bm metaphases: analysing circulating CD34+ cells by FISH is a sensitive, reliable method to measure the abnormal cell clones in pb. This method is practicable, non-invasive, representative for the clonal situation in the bm, and has a predictive value. Its feasibility was proven in a cohort of 27 MDS patients. (C) 2010 Elsevier Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.leukres.2010.01.010"],["dc.identifier.isi","000281214700007"],["dc.identifier.pmid","20226527"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18815"],["dc.notes.status","zu prĂĽfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0145-2126"],["dc.title","FISH analysis of circulating CD34+cells as a new tool for genetic monitoring in MDS: Verification of the method and application to 27 MDS patients"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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