Shirneshan, Katayoon

[["dc.bibliographiccitation.firstpage","43"],["dc.bibliographiccitation.journal","Oncology Research and Treatment"],["dc.bibliographiccitation.lastpage","44"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Kaempfe, Dietrich"],["dc.contributor.author","Machherndl-Spandl, Sigrid"],["dc.contributor.author","Suessner, Susanne"],["dc.contributor.author","Koziolek, Michael Johann"],["dc.contributor.author","Haase, Detlef"],["dc.contributor.author","Schanz, J."],["dc.date.accessioned","2018-11-07T09:34:10Z"],["dc.date.available","2018-11-07T09:34:10Z"],["dc.date.issued","2014"],["dc.identifier.isi","000343816900097"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32120"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.publisher.place","Basel"],["dc.relation.issn","2296-5262"],["dc.relation.issn","2296-5270"],["dc.title","Significance of Y-chromosome loss in MDS"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Haematologica"],["dc.bibliographiccitation.volume","101"],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Dierks, Sascha"],["dc.contributor.author","Glass, Bertram"],["dc.contributor.author","Stuhlmann, Reingard"],["dc.contributor.author","Baesecke, Joerg"],["dc.contributor.author","Sievers, B."],["dc.contributor.author","Simon-Becker, S."],["dc.contributor.author","Flach, J."],["dc.contributor.author","Martin, R."],["dc.contributor.author","Bacher, Ulrike"],["dc.contributor.author","Haase, Detlef"],["dc.date.accessioned","2018-11-07T10:13:03Z"],["dc.date.available","2018-11-07T10:13:03Z"],["dc.date.issued","2016"],["dc.format.extent","495"],["dc.identifier.isi","000379484601582"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40359"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Ferrata Storti Foundation"],["dc.publisher.place","Pavia"],["dc.relation.conference","21st Congress of the European-Hematology-Association"],["dc.relation.eventlocation","Copenhagen, DENMARK"],["dc.relation.issn","0390-6078"],["dc.title","SPATIAL INTERACTION OF CYTOGENETIC AND MOLECULAR MUTATIONS IN MYELODYSPLASTIC SYNDROMES"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","900"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Leukemia Research"],["dc.bibliographiccitation.lastpage","906"],["dc.bibliographiccitation.volume","37"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Jung, Klaus"],["dc.contributor.author","Schanz, Julie"],["dc.contributor.author","Götze, Katharina S."],["dc.contributor.author","Müller-Thomas, Catharina"],["dc.contributor.author","Platzbecker, Uwe"],["dc.contributor.author","Germing, Ulrich"],["dc.contributor.author","Brümmendorf, Tim H."],["dc.contributor.author","Bug, Gesine"],["dc.contributor.author","Ottmann, Oliver G."],["dc.contributor.author","Giagounidis, Aristoteles A. N."],["dc.contributor.author","Stadler, Michael"],["dc.contributor.author","Hofmann, Wolf-Karsten"],["dc.contributor.author","Schafhausen, Philippe"],["dc.contributor.author","Lübbert, Michael"],["dc.contributor.author","Schlenk, Richard F."],["dc.contributor.author","Blau, Igor W."],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Pfeiffer, Sebastian"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Metz, Michael"],["dc.contributor.author","Detken, Sven"],["dc.contributor.author","Seraphin, Jörg"],["dc.contributor.author","Jentsch-Ullrich, Kathleen"],["dc.contributor.author","Böhme, Angelika"],["dc.contributor.author","Schmidt, Burkhard C."],["dc.contributor.author","Trümper, Lorenz"],["dc.contributor.author","Haase, Detlef"],["dc.date.accessioned","2018-11-07T09:22:10Z"],["dc.date.available","2018-11-07T09:22:10Z"],["dc.date.issued","2013"],["dc.description.abstract","The gold standard of cytogenetic analysis in myelodysplastic syndromes (MDS) is conventional chromosome banding (CCB) analysis of bone marrow (BM) metaphases. Most aberrations can also be detected by fluorescence-in situ-hybridization (FISH). For this prospective multicenter German diagnostic study (www.clinicaltrials.gov: #NCT01355913) 360 patients, as yet, were followed up to 3 years by sequential FISH analyses of immunomagnetically enriched CD34+ peripheral blood (PB) cells using comprehensive FISH probe panels, resulting in a total number of 19,516 FISH analyses. We demonstrate that CD34+ PB FISH correlates significantly with CCB analysis and represents a feasible method for a reliable non-invasive cytogenetic monitoring from PB. (C) 2013 Elsevier Ltd. All rights reserved."],["dc.description.sponsorship","Celgene(R) Germany"],["dc.identifier.doi","10.1016/j.leukres.2013.03.019"],["dc.identifier.isi","000321111900012"],["dc.identifier.pmid","23623559"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/29278"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.notes.submitter","Najko"],["dc.relation.issn","0145-2126"],["dc.title","Molecular cytogenetic monitoring from CD34+peripheral blood cells in myelodysplastic syndromes: First results from a prospective multicenter German diagnostic study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Onkologie"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Schanz, J."],["dc.contributor.author","Goetze, K."],["dc.contributor.author","Mueller-Thomas, Catharina"],["dc.contributor.author","Platzbecker, Uwe"],["dc.contributor.author","Germing, U."],["dc.contributor.author","Bruemmendorf, Tim Hendrik"],["dc.contributor.author","Bug, G."],["dc.contributor.author","Giagounidis, Aristoteles A. N."],["dc.contributor.author","Nolte, F."],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Metz, M."],["dc.contributor.author","Truemper, Lorenz H."],["dc.contributor.author","Haase, Detlef"],["dc.date.accessioned","2018-11-07T09:19:07Z"],["dc.date.available","2018-11-07T09:19:07Z"],["dc.date.issued","2013"],["dc.format.extent","230"],["dc.identifier.isi","000326360900578"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28561"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.publisher.place","Basel"],["dc.relation.issn","1423-0240"],["dc.relation.issn","0378-584X"],["dc.title","Karyotype evolution in MDS patients detected by CD34+PB - FISH first results of the ongoing prospective multi-center German diagnostic study"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","21"],["dc.bibliographiccitation.journal","Blood"],["dc.bibliographiccitation.volume","116"],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Sole, Francesc"],["dc.contributor.author","Mallo, Mar"],["dc.contributor.author","Cervera, Jose"],["dc.contributor.author","Luno, Elisa"],["dc.contributor.author","Hildebrandt, Barbara"],["dc.contributor.author","Steidl, Christian"],["dc.contributor.author","Fonatsch, Christa"],["dc.contributor.author","Pfeilstoecker, Michael"],["dc.contributor.author","Noesslinger, Thomas"],["dc.contributor.author","Valent, Peter"],["dc.contributor.author","Giagounidis, Aristoteles A. N."],["dc.contributor.author","Aul, Carlo"],["dc.contributor.author","Luebbert, Michael"],["dc.contributor.author","Stauder, Reinhard"],["dc.contributor.author","Krieger, Otto"],["dc.contributor.author","Le Beau, Michelle M."],["dc.contributor.author","Bennett, John M."],["dc.contributor.author","Greenberg, Peter L."],["dc.contributor.author","Germing, Ulrich"],["dc.contributor.author","Haase, Detlef"],["dc.contributor.author","Schanz, Julie"],["dc.date.accessioned","2018-11-07T08:36:47Z"],["dc.date.available","2018-11-07T08:36:47Z"],["dc.date.issued","2010"],["dc.format.extent","1634"],["dc.identifier.isi","000289662204428"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18389"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Soc Hematology"],["dc.publisher.place","Washington"],["dc.relation.conference","52nd Annual Meeting of the American-Society-of-Hematology (ASH)"],["dc.relation.eventlocation","Orlando, FL"],["dc.relation.issn","0006-4971"],["dc.title","Loss of the Y Chromosome in MDS - Age-Related Phenomenon or Clonal Abnormality?"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

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[["dc.bibliographiccitation.firstpage","S21"],["dc.bibliographiccitation.journal","Der Internist"],["dc.bibliographiccitation.lastpage","S22"],["dc.bibliographiccitation.volume","57"],["dc.contributor.author","Westhofen, Gina"],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Bacher, Ulrike"],["dc.contributor.author","Beier, F."],["dc.contributor.author","Rassaf, Tienush"],["dc.contributor.author","Martin, R."],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Al-Ali, Haifa Kathrin"],["dc.contributor.author","Bruemmendorf, Tim Hendrik"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Germing, U."],["dc.contributor.author","Stuhlmann, Reingard"],["dc.contributor.author","Gattermann, Norbert"],["dc.contributor.author","Haase, Detlef"],["dc.date.accessioned","2018-11-07T10:15:57Z"],["dc.date.available","2018-11-07T10:15:57Z"],["dc.date.issued","2016"],["dc.identifier.isi","000375417500037"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/40929"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","New york"],["dc.relation.issn","1432-1289"],["dc.relation.issn","0020-9554"],["dc.title","Evidence of a significant Correlation of Iron Overloading with increased genetic Instability through comprehensive genetic Analysis in Patients with Myelodysplastic Syndromes"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1623"],["dc.bibliographiccitation.issue","21"],["dc.bibliographiccitation.journal","Blood"],["dc.bibliographiccitation.lastpage","1624"],["dc.bibliographiccitation.volume","118"],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Kaempfe, Dietrich"],["dc.contributor.author","Platzbecker, Uwe"],["dc.contributor.author","Soeling, Ulrike"],["dc.contributor.author","Bramlage, Carsten Paul"],["dc.contributor.author","Legler, Tobias Joerg"],["dc.contributor.author","Haase, Detlef"],["dc.contributor.author","Schanz, Julie"],["dc.date.accessioned","2018-11-07T08:49:47Z"],["dc.date.available","2018-11-07T08:49:47Z"],["dc.date.issued","2011"],["dc.identifier.isi","000299597105528"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21543"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Soc Hematology"],["dc.publisher.place","Washington"],["dc.relation.eventlocation","San Diego, CA"],["dc.relation.issn","0006-4971"],["dc.title","Proof of Y-Loss As Clonal Abnormality in MDS by Comparative Analysis of CD34+and CD3+Peripheral Blood Cells"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","239"],["dc.bibliographiccitation.journal","Onkologie"],["dc.bibliographiccitation.lastpage","240"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Schanz, J."],["dc.contributor.author","Neesen, J."],["dc.contributor.author","Salinas-Riester, Gabriela"],["dc.contributor.author","Platzbecker, Uwe"],["dc.contributor.author","Haase, Detlef"],["dc.date.accessioned","2018-11-07T09:19:08Z"],["dc.date.available","2018-11-07T09:19:08Z"],["dc.date.issued","2013"],["dc.identifier.isi","000326360900603"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28564"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.publisher.place","Basel"],["dc.relation.issn","1423-0240"],["dc.relation.issn","0378-584X"],["dc.title","Copy number profiles of high-risk MDS and AML patients"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","717"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Genes Chromosomes and Cancer"],["dc.bibliographiccitation.lastpage","724"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","Ganster, Christina"],["dc.contributor.author","Kaempfe, Dietrich"],["dc.contributor.author","Jung, Klaus"],["dc.contributor.author","Braulke, Friederike"],["dc.contributor.author","Shirneshan, Katayoon"],["dc.contributor.author","Machherndl-Spandl, Sigrid"],["dc.contributor.author","Suessner, Susanne"],["dc.contributor.author","Bramlage, Carsten Paul"],["dc.contributor.author","Legler, Tobias Joerg"],["dc.contributor.author","Koziolek, Michael Johann"],["dc.contributor.author","Haase, Detlef"],["dc.contributor.author","Schanz, Julie"],["dc.date.accessioned","2018-11-07T09:48:35Z"],["dc.date.available","2018-11-07T09:48:35Z"],["dc.date.issued","2015"],["dc.description.abstract","Loss of the Y-chromosome (LOY) is described as both a normal age-related event and a marker of a neoplastic clone in hematologic diseases. To assess the significance of LOY in myelodysplastic syndromes (MDS), we determined the percentage of LOY in clonal CD34+ peripheral blood cells in comparison to normal CD3+ T-cells of 27 MDS patients using fluorescence in situ hybridization (FISH) analysis. Results were compared with the percentage of LOY in CD34+ and CD3+ cells of 32 elderly men without hematologic diseases and in 25 young blood donors. While LOY could not be detected in CD3+ cells of young men, it was observed in CD3+ cells of elderly men without hematologic diseases (2.5% LOY) as well as in CD3+ cells of elderly MDS patients (5.8% LOY). The percentage of CD34+ cells affected by LOY was significantly higher in MDS patients compared to elderly men without hematologic diseases (43.3% vs. 13.2%, P = 0.005), indicating that LOY has an age-related basis but is also associated with MDS. Furthermore, we aimed to define a threshold between age- and disease-associated LOY in MDS. Statistical analysis revealed that a value of 21.5% LOY in CD34+ peripheral blood cells provided the best threshold to discriminate between these two conditions in MDS. We conclude that LOY is clonal in a substantial number of MDS based on an age-related predisposition. (C) 2015 Wiley Periodicals, Inc."],["dc.description.sponsorship","Jose Carreras Leukamie-Stiftung [R 12/20]"],["dc.identifier.doi","10.1002/gcc.22282"],["dc.identifier.isi","000365405700001"],["dc.identifier.pmid","26394808"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/35338"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.relation.issn","1098-2264"],["dc.relation.issn","1045-2257"],["dc.title","New Data Shed Light on Y-Loss-Related Pathogenesis in Myelodysplastic Syndromes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]