Schuster, Andreas

[["dc.bibliographiccitation.journal","Journal of the American Society of Echocardiography"],["dc.contributor.author","Li, Ling"],["dc.contributor.author","Jani, Vivek"],["dc.contributor.author","Craft, Mary"],["dc.contributor.author","Olson, Joan"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Pedrizzetti, Gianni"],["dc.contributor.author","Danford, David"],["dc.contributor.author","Kutty, Shelby"],["dc.date.accessioned","2022-10-04T10:21:57Z"],["dc.date.available","2022-10-04T10:21:57Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1016/j.echo.2022.08.011"],["dc.identifier.pii","S0894731722004485"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114546"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-600"],["dc.relation.issn","0894-7317"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","Ventricular Flow Profile in Young Patients with Single Left Ventricle Fontan using Echocardiographic Contrast Particle Imaging Velocimetry"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","136"],["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.bibliographiccitation.lastpage","142"],["dc.bibliographiccitation.volume","248"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Shang, Quanliang"],["dc.contributor.author","Joseph, Navya"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Danford, David A."],["dc.contributor.author","Beerbaum, Phillip"],["dc.contributor.author","Sarikouch, Samir"],["dc.date.accessioned","2020-12-10T14:24:31Z"],["dc.date.available","2020-12-10T14:24:31Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1016/j.ijcard.2017.06.121"],["dc.identifier.issn","0167-5273"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/72276"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Abnormal right atrial performance in repaired tetralogy of Fallot: A CMR feature tracking analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","International Journal of Cardiology"],["dc.contributor.author","Backhaus, Sören J."],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Stiermaier, Thomas"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","Koschalka, Alexander"],["dc.contributor.author","Navarra, Jenny-Lou"],["dc.contributor.author","Uhlig, Johannes"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Bigalke, Boris"],["dc.contributor.author","Gutberlet, Matthias"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Thiele, Holger"],["dc.contributor.author","Eitel, Ingo"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2019-08-06T12:07:43Z"],["dc.date.available","2019-08-06T12:07:43Z"],["dc.date.issued","2019"],["dc.description.abstract","Sex-specific outcome data following myocardial infarction (MI) are inconclusive with some evidence suggesting association of female sex and increased major adverse cardiac events (MACE). Since mechanistic principles remain elusive, we aimed to quantify the underlying phenotype using cardiovascular magnetic resonance (CMR) quantitative deformation imaging and tissue characterisation."],["dc.identifier.doi","10.1016/j.ijcard.2019.06.036"],["dc.identifier.pmid","31300172"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62311"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.relation.eissn","1874-1754"],["dc.relation.issn","0167-5273"],["dc.title","Atrioventricular mechanical coupling and major adverse cardiac events in female patients following acute ST elevation myocardial infarction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e109164"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Lamata, Pablo"],["dc.contributor.author","Hussain, Shazia T."],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Bigalke, Boris"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2017-09-07T11:45:27Z"],["dc.date.available","2017-09-07T11:45:27Z"],["dc.date.issued","2014"],["dc.description.abstract","Objectives: Cardiovascular magnetic resonance feature tracking (CMR-FT) offers quantification of myocardial deformation from routine cine images. However, data using CMR-FT to quantify left ventricular (LV) torsion and diastolic recoil are not yet available. We therefore sought to evaluate the feasibility and reproducibility of CMR-FT to quantify LV torsion and peak recoil rate using an optimal anatomical approach. Methods: Short-axis cine stacks were acquired at rest and during dobutamine stimulation (10 and 20 mu g.kg(-1).min(-1)) in 10 healthy volunteers. Rotational displacement was analysed for all slices. A complete 3D-LV rotational model was developed using linear interpolation between adjacent slices. Torsion was defined as the difference between apical and basal rotation, divided by slice distance. Depending on the distance between the most apical (defined as 0% LV distance) and basal (defined as 100% LV distance) slices, four different models for the calculation of torsion were examined: Model-1 (25-75%), Model-2 (0-100%), Model-3 (25-100%) and Model-4 (0-75%). Analysis included subendocardial, subepicardial and global torsion and recoil rate (mean of subendocardial and subepicardial values). Results: Quantification of torsion and recoil rate was feasible in all subjects. There was no significant difference between the different models at rest. However, only Model-1 (25-75%) discriminated between rest and stress (Global Torsion: 2.7 +/- 1.5 degrees cm(-1), 3.6 +/- 2.0 degrees cm(-1), 5.1 +/- 2.2 degrees cm(-1), p<0.01; Global Recoil Rate: -30.1 +/- 11.1 degrees cm(-1) s (-1), -469 +/- 15.0 degrees cm (-1) s (-1), -68.9 +/- 32.3 degrees cm(-1) s(-1), p<0.01; for rest, 10 and 20 mu g.kg(-1).min(-1) of dobutamine, respectively). Reproducibility was sufficient for all parameters as determined by Bland-Altman analysis, intraclass correlation coefficients and coefficient of variation. Conclusions: CMR-FT based derivation of myocardial torsion and recoil rate is feasible and reproducible at rest and with dobutamine stress. Using an optimal anatomical approach measuring rotation at 25% and 75% apical and basal LV locations allows effective quantification of torsion and recoil dynamics. Application of these new measures of deformation by CMR-FT should next be explored in disease states."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2014"],["dc.identifier.doi","10.1371/journal.pone.0109164"],["dc.identifier.gro","3142035"],["dc.identifier.isi","000345743700050"],["dc.identifier.pmid","25285656"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10994"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/3823"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Quantification of Left Ventricular Torsion and Diastolic Recoil Using Cardiovascular Magnetic Resonance Myocardial Feature Tracking"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","670"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","European Heart Journal - Cardiovascular Imaging"],["dc.bibliographiccitation.lastpage","675"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Hoesch, Olga"],["dc.contributor.author","Thuy-Trang Ngyuen, Thuy-Trang Ngyuen"],["dc.contributor.author","Lauerer, Peter"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Steinmetz, Michael"],["dc.date.accessioned","2018-11-07T09:56:17Z"],["dc.date.available","2018-11-07T09:56:17Z"],["dc.date.issued","2015"],["dc.description.abstract","Aims Ebstein's anomaly (EA) involves a displaced and dysplastic tricuspid valve resulting in an atrialized portion of the right ventricle and an enlargement of the functional right ventricle and right atrium. Biomarkers targeting heart failure such as brain natriuretic peptide (BNP) or haematological parameters [haemoglobin (Hb) and haematocrit (Hct)] are upregulated in states of pulmonary hypoperfusion. We hypothesized that decreased pulmonary perfusion dependent on the stage of right heart failure is a possible mechanism in EA, and that it can be correlated with cardiac magnetic resonance (CMR) parameters. The aim of this study was to investigate the relationship between BNP and haematological parameters with functional parameters from CMR and exercise testing in patients with EA. Methods and results Twenty-five patients with non-corrected EA were studied prospectively (mean age 26 +/- 14 years). BNP level was increased (74 +/- 127 ng/L), and in 16% markedly above the heart failure cut-off level of 100 ng/L. Hb and Hct were increased above normal levels in 20 and 24% of patients, respectively. BNP and Hct/Hb correlated with CMR [total right/left (R/L)-Volume-Index, right atrium-end-diastolic volume index (EDVi), functional right ventricle (fRV)-EDVi, fRV-ejection fraction (EF), tricuspid regurgitation, pulmonary artery flow, and left ventricular EF] and exercise testing [workload/kg, oxygen uptake (VO2), ventilatory response to carbon dioxide production (VE/VCO2), oxygen (O-2) pulse, and heart rate reserve]. The higher BNP and haematological parameters, the higher was the disease severity and the more limited was the physical exercise capacity. Conclusion In this EA cohort, BNP levels and haematological parameters correlated well with functional data from CMR and exercise testing. The total R/L-Volume-Index and BNP, and to some extent hematological parameters, may be useful as prognostic markers in patients with EA."],["dc.description.sponsorship","Faculty of Medicine, Georg-August-University Gottingen, Germany"],["dc.identifier.doi","10.1093/ehjci/jeu312"],["dc.identifier.isi","000358014000013"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/36927"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","2047-2412"],["dc.relation.issn","2047-2404"],["dc.title","BNP and haematological parameters are markers of severity of Ebstein's anomaly: correlation with CMR and cardiopulmonary exercise testing"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1262"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","European Heart Journal - Cardiovascular Imaging"],["dc.bibliographiccitation.lastpage","1270"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Backhaus, Sören J"],["dc.contributor.author","Stiermaier, Thomas"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Stulle, Alina"],["dc.contributor.author","Koschalka, Alexander"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Bigalke, Boris"],["dc.contributor.author","Gutberlet, Matthias"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Thiele, Holger"],["dc.contributor.author","Eitel, Ingo"],["dc.date.accessioned","2020-04-03T13:12:22Z"],["dc.date.available","2020-04-03T13:12:22Z"],["dc.date.issued","2019-11-01"],["dc.description.abstract","Cardiovascular magnetic resonance feature tracking (CMR-FT) global longitudinal strain (GLS) provides incremental prognostic value following acute myocardial infarction (AMI) but requires substantial post-processing. Alternatively, manual global long-axis strain (LAS) can be easily assessed from standard steady state free precession images. We aimed to define the prognostic value of LAS in a large multicentre study in patients following AMI."],["dc.identifier.doi","10.1093/ehjci/jez077"],["dc.identifier.pmid","31329854"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/63616"],["dc.language.iso","en"],["dc.relation.eissn","2047-2412"],["dc.relation.issn","2047-2404"],["dc.relation.issn","2047-2412"],["dc.title","Fast manual long-axis strain assessment provides optimized cardiovascular event prediction following myocardial infarction"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Circulation"],["dc.contributor.author","Backhaus, Sören J"],["dc.contributor.author","Lange, Torben"],["dc.contributor.author","George, Elisabeth F"],["dc.contributor.author","Hellenkamp, Kristian"],["dc.contributor.author","Gertz, Roman J"],["dc.contributor.author","Billing, Marcus"],["dc.contributor.author","Wachter, Rolf"],["dc.contributor.author","Steinmetz, Michael"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Raaz, Uwe"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Friede, Tim"],["dc.contributor.author","Uecker, Martin"],["dc.contributor.author","Hasenfuß, Gerd P."],["dc.contributor.author","Seidler, Tim"],["dc.contributor.author","Schuster, Andreas"],["dc.date.accessioned","2021-03-08T07:13:50Z"],["dc.date.available","2021-03-08T07:13:50Z"],["dc.date.issued","2021-01-21"],["dc.description.abstract","Background: Right heart catheterisation (RHC) using exercise-stress is the reference standard for the diagnosis of heart failure with preserved ejection fraction (HFpEF) but carries the risk of the invasive procedure. We hypothesized that real-time cardiovascular magnetic resonance (RT-CMR) exercise imaging with pathophysiologic data at excellent temporal and spatial resolution may represent a contemporary non-invasive alternative for diagnosing HFpEF. Methods: The HFpEF stress trial (DZHK-17, NCT03260621) prospectively recruited 75 patients with echocardiographic signs of diastolic dysfunction and dyspnea on exertion (E/e'>8, New York Heart Association (NYHA) class ≥II) to undergo echocardiography, RHC and RT-CMR at rest and during exercise-stress. HFpEF was defined according to pulmonary capillary wedge pressure (PCWP ≥15mmHg at rest or ≥25mmHg during exercise stress). RT-CMR functional assessments included time-volume curves for total and early (1/3) diastolic left ventricular (LV) filling, left atrial (LA) emptying and LV/LA long axis strain (LAS). Results: HFpEF patients (n=34, median PCWP rest 13mmHg, stress 27mmHg) had higher E/e' (12.5 vs. 9.15), NT-proBNP (255 vs. 75ng/l) and LA volume index (43.8 vs. 36.2ml/m2) compared to non-cardiac dyspnea patients (n=34, rest 8mmHg, stress 18mmHg, p≤0.001 for all). Seven patients were excluded due to the presence of non HFpEF cardiac disease causing dyspnea on imaging. There were no differences in RT-CMR LV total and early diastolic filling at rest and during exercise-stress (p≥0.164) between HFpEF and non-cardiac dyspnea. RT-CMR revealed significantly impaired LA total and early (p<0.001) diastolic emptying in HFpEF during exercise-stress. RT-CMR exercise-stress LA LAS was independently associated with HFpEF (adjusted odds ratio 0.657, 95% confidence interval [0.516; 0.838], p=0.001) after adjustment for clinical and imaging parameters and emerged as the best predictor for HFpEF (area under the curve rest 0.82 vs. exercise-stress 0.93, p=0.029). Conclusions: RT-CMR allows highly accurate identification of HFpEF during physiological exercise and qualifies as a suitable non-invasive diagnostic alternative. These results will need to be confirmed in multi-centre prospective research studies to establish widespread routine clinical use. Clinical Trial Registration: URL: https://www.clinicaltrials.gov Unique Identifier: NCT03260621."],["dc.identifier.doi","10.1161/CIRCULATIONAHA.120.051542"],["dc.identifier.pmid","33472397"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/80476"],["dc.identifier.url","https://mbexc.uni-goettingen.de/literature/publications/302"],["dc.language.iso","en"],["dc.relation","EXC 2067: Multiscale Bioimaging"],["dc.relation.issn","0009-7322"],["dc.relation.issn","1524-4539"],["dc.relation.workinggroup","RG Hasenfuß"],["dc.relation.workinggroup","RG Uecker"],["dc.title","Exercise-Stress Real-time Cardiac Magnetic Resonance Imaging for Non-Invasive Characterisation of Heart Failure with Preserved Ejection Fraction: The HFpEF Stress Trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","601"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Circulation Cardiovascular Imaging"],["dc.bibliographiccitation.lastpage","609"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Hoesch, Olga"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Thuy-Trang Nguyen, Thuy-Trang Nguyen"],["dc.contributor.author","Lauerer, Peter"],["dc.contributor.author","Rosenberg, Christina"],["dc.contributor.author","Kowallick, Johannes Tammo"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Unterberg, Christina"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Fasshauer, Martin"],["dc.contributor.author","Staab, Wieland"],["dc.contributor.author","Paul, Thomas"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Steinmetz, Michael"],["dc.date.accessioned","2018-11-07T09:38:08Z"],["dc.date.available","2018-11-07T09:38:08Z"],["dc.date.issued","2014"],["dc.description.abstract","Background-The classification of clinical severity of Ebstein anomaly still remains a challenge. The aim of this study was to focus on the interaction of the pathologically altered right heart with the anatomically-supposedly-normal left heart and to derive from cardiac magnetic resonance (CMR) a simple imaging measure for the clinical severity of Ebstein anomaly. Methods and Results-Twenty-five patients at a mean age of 26 +/- 14 years with unrepaired Ebstein anomaly were examined in a prospective study. Disease severity was classified using CMR volumes and functional measurements in comparison with heart failure markers from clinical data, ECG, laboratory and cardiopulmonary exercise testing, and echocardiography. All examinations were completed within 24 hours. A total right/left-volume index was defined from end-diastolic volume measurements in CMR: total right/left-volume index=(RA+aRV+fRV)/(LA+LV). Mean total right/left-volume index was 2.6 +/- 1.7 (normal values: 1.1 +/- 0.1). This new total right/left-volume index correlated with almost all clinically used biomarkers of heart failure: brain natriuretic peptide (r=0.691; P=0.0003), QRS (r=0.432; P=0.039), peak oxygen consumption/kg (r=-0.479; P=0.024), ventilatory response to carbon dioxide production at anaerobic threshold (r=0.426; P=0.048), the severity of tricuspid regurgitation (r=0.692; P=0.009), tricuspid valve offset (r=0.583; P=0.004), and tricuspid annular plane systolic excursion (r=0.554; P=0.006). Previously described severity indices ([RA+aRV]/[fRV+LA+LV]) and fRV/LV end-diastolic volume corresponded only to some parameters. Conclusions-In patients with Ebstein anomaly, the easily acquired index of right-sided to left-sided heart volumes from CMR correlated well with established heart failure markers. Our data suggest that the total right/left-volume index should be used as a new and simplified CMR measure, allowing more accurate assessment of disease severity than previously described scoring systems."],["dc.identifier.doi","10.1161/CIRCIMAGING.113.001467"],["dc.identifier.isi","000339172100006"],["dc.identifier.pmid","24807407"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33001"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","1942-0080"],["dc.relation.issn","1941-9651"],["dc.title","The Total Right/Left-Volume Index: A New and Simplified Cardiac Magnetic Resonance Measure to Evaluate the Severity of Ebstein Anomaly of the Tricuspid Valve A Comparison With Heart Failure Markers From Various Modalities"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","60"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Cardiovascular Magnetic Resonance"],["dc.bibliographiccitation.volume","23"],["dc.contributor.author","Metschies, Georg"],["dc.contributor.author","Billing, Marcus"],["dc.contributor.author","Schmidt-Rimpler, Jonas"],["dc.contributor.author","Kowallick, Johannes T."],["dc.contributor.author","Gertz, Roman J."],["dc.contributor.author","Lapinskas, Tomas"],["dc.contributor.author","Pieske-Kraigher, Elisabeth"],["dc.contributor.author","Pieske, Burkert"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Bigalke, Boris"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Kelle, Sebastian"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Backhaus, Sören J."],["dc.date.accessioned","2021-11-25T11:12:48Z"],["dc.date.available","2021-11-25T11:12:48Z"],["dc.date.issued","2021-05-17"],["dc.date.updated","2021-11-19T12:47:36Z"],["dc.description.abstract","Abstract Background Myocardial deformation analyses using cardiovascular magnetic resonance (CMR) feature tracking (CMR-FT) have incremental value in the assessment of cardiac function beyond volumetric analyses. Since guidelines do not recommend specific imaging parameters, we aimed to define optimal spatial and temporal resolutions for CMR cine images to enable reliable post-processing. Methods Intra- and inter-observer reproducibility was assessed in 12 healthy subjects and 9 heart failure (HF) patients. Cine images were acquired with different temporal (20, 30, 40 and 50 frames/cardiac cycle) and spatial resolutions (high in-plane 1.5 × 1.5 mm through-plane 5 mm, standard 1.8 × 1.8 x 8mm and low 3.0 × 3.0 x 10mm). CMR-FT comprised left ventricular (LV) global and segmental longitudinal/circumferential strain (GLS/GCS) and associated systolic strain rates (SR), and right ventricular (RV) GLS. Results Temporal but not spatial resolution did impact absolute strain and SR. Maximum absolute changes between lowest and highest temporal resolution were as follows: 1.8% and 0.3%/s for LV GLS and SR, 2.5% and 0.6%/s for GCS and SR as well as 1.4% for RV GLS. Changes of strain values occurred comparing 20 and 30 frames/cardiac cycle including LV and RV GLS and GCS (p < 0.001–0.046). In contrast, SR values (LV GLS/GCS SR) changed significantly comparing all successive temporal resolutions (p < 0.001–0.013). LV strain and SR reproducibility was not affected by either temporal or spatial resolution, whilst RV strain variability decreased with augmentation of temporal resolution. Conclusion Temporal but not spatial resolution significantly affects strain and SR in CMR-FT deformation analyses. Strain analyses require lower temporal resolution and 30 frames/cardiac cycle offer consistent strain assessments, whilst SR measurements gain from further increases in temporal resolution."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2021"],["dc.identifier.citation","Journal of Cardiovascular Magnetic Resonance. 2021 May 17;23(1):60"],["dc.identifier.doi","10.1186/s12968-021-00740-5"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/93537"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.publisher","BioMed Central"],["dc.relation.eissn","1532-429X"],["dc.relation.orgunit","Klinik für Kardiologie und Pneumologie"],["dc.rights","CC BY 4.0"],["dc.rights.holder","The Author(s)"],["dc.subject","Myocardial deformation"],["dc.subject","Strain"],["dc.subject","Cardiovascular magnetic resonance"],["dc.subject","Temporal resolution"],["dc.subject","Spatial resolution"],["dc.subject","Reproducibility"],["dc.title","Defining the optimal temporal and spatial resolution for cardiovascular magnetic resonance imaging feature tracking"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","296"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","European Journal of Radiology"],["dc.bibliographiccitation.lastpage","301"],["dc.bibliographiccitation.volume","82"],["dc.contributor.author","Schuster, Andreas"],["dc.contributor.author","Morton, Geraint"],["dc.contributor.author","Hussain, Shazia T."],["dc.contributor.author","Jogiya, Roy"],["dc.contributor.author","Kutty, Shelby"],["dc.contributor.author","Asrress, Kaleab N."],["dc.contributor.author","Makowski, Marcus R."],["dc.contributor.author","Bigalke, Boris"],["dc.contributor.author","Perera, Divaka"],["dc.contributor.author","Beerbaum, Philipp"],["dc.contributor.author","Nagel, Eike"],["dc.date.accessioned","2018-11-07T09:28:50Z"],["dc.date.available","2018-11-07T09:28:50Z"],["dc.date.issued","2013"],["dc.description.abstract","Background: Cardiovascular magnetic resonance myocardial feature tracking (CMR-FT) is a promising novel method for quantification of myocardial wall mechanics from standard steady-state free precession (SSFP) images. We sought to determine whether magnetic field strength affects the intra-observer reproducibility of CMR-FT strain analysis. Methods: We studied 2 groups, each consisting of 10 healthy subjects, at 1.5 T or 3 T Analysis was performed at baseline and after 4 weeks using dedicated CMR-FT prototype software (Tomtec, Germany) to analyze standard SSFP cine images. Right ventricular (RV) and left ventricular (LV) longitudinal strain (Ell(RV) and Ell(LV)) and LV long-axis radial strain (Err(LAX)) were derived from the 4-chamber cine, and LV shor-taxis circumferential and radial strains (Ecc(SAX), Err(SAX)) from the short-axis orientation. Strain parameters were assessed together with LV ejection fraction (EF) and volumes. Intra-observer reproducibility was determined by comparing the first and the second analysis in both groups. Results: In all volunteers resting strain parameters were successfully derived from the SSFP images. There was no difference in strain parameters, volumes and EF between field strengths (p > 0.05). In general EccSAX was the most reproducible strain parameter as determined by the coefficient of variation (CV) at 1.5 T (CV 13.3% and 46% global and segmental respectively) and 3 T (CV 17.2% and 31.1% global and segmental respectively). The least reproducible parameter was EllRV (CV 1.5 T 28.7% and 53.2%; 3 T 43.5% and 63.3% global and segmental respectively). Conclusions: CMR-FT results are similar with reasonable intra-observer reproducibility in different groups of volunteers at 1.5 T and 3 T. CMR-FT is a promising novel technique and our data indicate that results might be transferable between field strengths. However there is a considerable amount of segmental variability indicating that further refinements are needed before CMR-FT can be fully established in clinical routine for quantitative assessment of wall mechanics and strain. (C) 2012 Elsevier Ireland Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.ejrad.2012.11.012"],["dc.identifier.isi","000313093800023"],["dc.identifier.pmid","23246014"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30879"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","0720-048X"],["dc.title","The intra-observer reproducibility of cardiovascular magnetic resonance myocardial feature tracking strain assessment is independent of field strength"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]