Pöhlmann, Stefan

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[["dc.bibliographiccitation.artnumber","S2211124721008287"],["dc.bibliographiccitation.firstpage","109415"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Cell Reports"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Hofmann-Winkler, Heike"],["dc.contributor.author","Krüger, Nadine"],["dc.contributor.author","Kempf, Amy"],["dc.contributor.author","Nehlmeier, Inga"],["dc.contributor.author","Graichen, Luise"],["dc.contributor.author","Arora, Prerna"],["dc.contributor.author","Sidarovich, Anzhalika"],["dc.contributor.author","Moldenhauer, Anna-Sophie"],["dc.contributor.author","Winkler, Martin S."],["dc.contributor.author","Pöhlmann, Stefan"],["dc.date.accessioned","2021-09-01T06:42:36Z"],["dc.date.available","2021-09-01T06:42:36Z"],["dc.date.issued","2021"],["dc.identifier.doi","10.1016/j.celrep.2021.109415"],["dc.identifier.pii","S2211124721008287"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/89097"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-455"],["dc.relation.issn","2211-1247"],["dc.title","SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","18022"],["dc.bibliographiccitation.issue","42"],["dc.bibliographiccitation.journal","Journal of the American Chemical Society"],["dc.bibliographiccitation.lastpage","18034"],["dc.bibliographiccitation.volume","142"],["dc.contributor.author","Budhadev, Darshita"],["dc.contributor.author","Poole, Emma"],["dc.contributor.author","Nehlmeier, Inga"],["dc.contributor.author","Liu, Yuanyuan"],["dc.contributor.author","Hooper, James"],["dc.contributor.author","Kalverda, Elizabeth"],["dc.contributor.author","Akshath, Uchangi Satyaprasad"],["dc.contributor.author","Hondow, Nicole"],["dc.contributor.author","Turnbull, W. Bruce"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.author","Guo, Yuan"],["dc.contributor.author","Zhou, Dejian"],["dc.date.accessioned","2021-04-14T08:31:53Z"],["dc.date.available","2021-04-14T08:31:53Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1021/jacs.0c06793"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/83741"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1520-5126"],["dc.relation.issn","0002-7863"],["dc.title","Glycan-Gold Nanoparticles as Multifunctional Probes for Multivalent Lectin–Carbohydrate Binding: Implications for Blocking Virus Infection and Nanoparticle Assembly"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e01488-16"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Virology"],["dc.bibliographiccitation.volume","91"],["dc.contributor.author","Wrensch, Florian"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Gärtner, Sabine"],["dc.contributor.author","Nehlmeier, Inga"],["dc.contributor.author","Winkler, Michael"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.editor","Ross, Susan R."],["dc.date.accessioned","2022-10-06T13:25:35Z"],["dc.date.available","2022-10-06T13:25:35Z"],["dc.date.issued","2017"],["dc.description.abstract","ABSTRACT\n Interferon-induced transmembrane proteins (IFITMs) can inhibit the cellular entry of several enveloped viruses, including simian immunodeficiency virus (SIV). The blockade of SIV by IFITMs is isolate specific, raising the question of which parameters impact sensitivity to IFITM. We show that the virion context in which SIV-Env is presented and the efficiency of virion incorporation determine Env susceptibility to inhibition by IFITMs. Thus, determinants other than the nature of the envelope protein can impact the IFITM sensitivity of viral entry.\n \n IMPORTANCE\n The host cell-encoded IFITM proteins can block viral entry and are an important component of the innate defenses against viral infection. However, the determinants controlling whether a virus is susceptible to blockade by IFITM proteins are incompletely understood. Our study shows that the amount of envelope proteins incorporated into virions as well as the nature of the virion particle itself can impact the sensitivity of viral entry to IFITMs. These results show for the first time that determinants other than the viral envelope protein can impact sensitivity to IFITM and have implications for the interpretation of previously published data on inhibition of viruses by IFITM proteins. Moreover, our findings might help to define the mechanism underlying the antiviral activity of IFITM proteins."],["dc.description.sponsorship"," Leibniz-Gemeinschaft https://doi.org/10.13039/501100001664"],["dc.identifier.doi","10.1128/JVI.01488-16"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114874"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1098-5514"],["dc.relation.issn","0022-538X"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.rights.uri","http://creativecommons.org/licenses/by/4.0/"],["dc.title","Virion Background and Efficiency of Virion Incorporation Determine Susceptibility of Simian Immunodeficiency Virus Env-Driven Viral Entry to Inhibition by IFITM Proteins"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Virology"],["dc.bibliographiccitation.volume","93"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Nehlmeier, Inga"],["dc.contributor.author","Brinkmann, Constantin"],["dc.contributor.author","Krähling, Verena"],["dc.contributor.author","Behner, Laura"],["dc.contributor.author","Moldenhauer, Anna-Sophie"],["dc.contributor.author","Krüger, Nadine"],["dc.contributor.author","Nehls, Julia"],["dc.contributor.author","Schindler, Michael"],["dc.contributor.author","Hoenen, Thomas"],["dc.contributor.author","Maisner, Andrea"],["dc.contributor.author","Becker, Stephan"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.editor","Dermody, Terence S."],["dc.date.accessioned","2020-12-10T18:37:03Z"],["dc.date.available","2020-12-10T18:37:03Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1128/JVI.01821-18"],["dc.identifier.eissn","1098-5514"],["dc.identifier.issn","0022-538X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/76825"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1073"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Journal of General Virology"],["dc.bibliographiccitation.lastpage","1078"],["dc.bibliographiccitation.volume","100"],["dc.contributor.author","Lambertz, Ruth L. O."],["dc.contributor.author","Gerhauser, Ingo"],["dc.contributor.author","Nehlmeier, Inga"],["dc.contributor.author","Leist, Sarah R."],["dc.contributor.author","Kollmus, Heike"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.author","Schughart, Klaus"],["dc.date.accessioned","2020-12-10T18:20:19Z"],["dc.date.available","2020-12-10T18:20:19Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1099/jgv.0.001274"],["dc.identifier.eissn","1465-2099"],["dc.identifier.issn","0022-1317"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/75522"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Tmprss2 knock-out mice are resistant to H10 influenza A virus pathogenesis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","447"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Cell"],["dc.bibliographiccitation.lastpage","456.e11"],["dc.bibliographiccitation.volume","185"],["dc.contributor.author","Hoffmann, Markus"],["dc.contributor.author","Krüger, Nadine"],["dc.contributor.author","Schulz, Sebastian"],["dc.contributor.author","Cossmann, Anne"],["dc.contributor.author","Rocha, Cheila"],["dc.contributor.author","Kempf, Amy"],["dc.contributor.author","Nehlmeier, Inga"],["dc.contributor.author","Graichen, Luise"],["dc.contributor.author","Moldenhauer, Anna-Sophie"],["dc.contributor.author","Winkler, Martin S."],["dc.contributor.author","Pöhlmann, Stefan"],["dc.date.accessioned","2022-04-01T10:00:59Z"],["dc.date.available","2022-04-01T10:00:59Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1016/j.cell.2021.12.032"],["dc.identifier.pii","S0092867421014951"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/105571"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-530"],["dc.relation.issn","0092-8674"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","The Lancet Infectious Diseases"],["dc.contributor.author","Arora, Prerna"],["dc.contributor.author","Kempf, Amy"],["dc.contributor.author","Nehlmeier, Inga"],["dc.contributor.author","Schulz, Sebastian R"],["dc.contributor.author","Jäck, Hans-Martin"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.author","Hoffmann, Markus"],["dc.date.accessioned","2022-12-01T08:30:45Z"],["dc.date.available","2022-12-01T08:30:45Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1016/S1473-3099(22)00733-2"],["dc.identifier.pii","S1473309922007332"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/117970"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-621"],["dc.relation.issn","1473-3099"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","Omicron sublineage BQ.1.1 resistance to monoclonal antibodies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1665"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","The Lancet Infectious Diseases"],["dc.bibliographiccitation.lastpage","1666"],["dc.bibliographiccitation.volume","22"],["dc.contributor.author","Arora, Prerna"],["dc.contributor.author","Zhang, Lu"],["dc.contributor.author","Nehlmeier, Inga"],["dc.contributor.author","Kempf, Amy"],["dc.contributor.author","Cossmann, Anne"],["dc.contributor.author","Dopfer-Jablonka, Alexandra"],["dc.contributor.author","Schulz, Sebastian R"],["dc.contributor.author","Jäck, Hans-Martin"],["dc.contributor.author","Behrens, Georg M N"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.author","Hoffmann, Markus"],["dc.date.accessioned","2022-12-01T08:30:45Z"],["dc.date.available","2022-12-01T08:30:45Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1016/S1473-3099(22)00693-4"],["dc.identifier.pii","S1473309922006934"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/117969"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-621"],["dc.relation.issn","1473-3099"],["dc.rights.uri","https://www.elsevier.com/tdm/userlicense/1.0/"],["dc.title","The effect of cilgavimab and neutralisation by vaccine-induced antibodies in emerging SARS-CoV-2 BA.4 and BA.5 sublineages"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Cellular & Molecular Immunology"],["dc.contributor.author","Arora, Prerna"],["dc.contributor.author","Kempf, Amy"],["dc.contributor.author","Nehlmeier, Inga"],["dc.contributor.author","Graichen, Luise"],["dc.contributor.author","Winkler, Martin S."],["dc.contributor.author","Lier, Martin"],["dc.contributor.author","Schulz, Sebastian"],["dc.contributor.author","Jäck, Hans-Martin"],["dc.contributor.author","Pöhlmann, Stefan"],["dc.contributor.author","Hoffmann, Markus"],["dc.date.accessioned","2022-02-01T10:31:08Z"],["dc.date.available","2022-02-01T10:31:08Z"],["dc.date.issued","2022"],["dc.description.abstract","Since the beginning of the COVID-19 pandemic, multiple SARS-CoV-2 variants have emerged. While some variants spread only locally, others, referred to as variants of concern, disseminated globally and became drivers of the pandemic. All SARS-CoV-2 variants harbor mutations relative to the virus circulating early in the pandemic, and mutations in the viral spike (S) protein are considered of particular relevance since the S protein mediates host cell entry and constitutes the key target of the neutralizing antibody response. As a consequence, mutations in the S protein may increase SARS-CoV-2 infectivity and enable its evasion of neutralizing antibodies. Furthermore, mutations in the S protein can modulate viral transmissibility and pathogenicity."],["dc.description.abstract","Since the beginning of the COVID-19 pandemic, multiple SARS-CoV-2 variants have emerged. While some variants spread only locally, others, referred to as variants of concern, disseminated globally and became drivers of the pandemic. All SARS-CoV-2 variants harbor mutations relative to the virus circulating early in the pandemic, and mutations in the viral spike (S) protein are considered of particular relevance since the S protein mediates host cell entry and constitutes the key target of the neutralizing antibody response. As a consequence, mutations in the S protein may increase SARS-CoV-2 infectivity and enable its evasion of neutralizing antibodies. Furthermore, mutations in the S protein can modulate viral transmissibility and pathogenicity."],["dc.identifier.doi","10.1038/s41423-021-00811-8"],["dc.identifier.pii","811"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/98791"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-517"],["dc.relation.eissn","2042-0226"],["dc.relation.issn","1672-7681"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","No evidence for increased cell entry or antibody evasion by Delta sublineage AY.4.2"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]