Streit, Frank

[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Clinical Chemistry"],["dc.bibliographiccitation.volume","52"],["dc.contributor.author","Domke, I."],["dc.contributor.author","Shipkova, Maria"],["dc.contributor.author","Engelmayer, J."],["dc.contributor.author","Kheradmand, M."],["dc.contributor.author","Luthe, Hilmar"],["dc.contributor.author","Pou, L."],["dc.contributor.author","Streit, Frank"],["dc.contributor.author","Vukovich, T."],["dc.contributor.author","Oellerich, M."],["dc.contributor.author","Wieland, Eberhard"],["dc.date.accessioned","2018-11-07T09:44:11Z"],["dc.date.available","2018-11-07T09:44:11Z"],["dc.date.issued","2006"],["dc.format.extent","A61"],["dc.identifier.isi","000237925900188"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34335"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Clinical Chemistry"],["dc.publisher.place","Washington"],["dc.relation.conference","58th Annual Meeting of the American-Association-of-Clinical-Chemistry"],["dc.relation.eventlocation","Chicago, IL"],["dc.relation.issn","0009-9147"],["dc.title","Cyclosporin determination with different immunoassays in four laboratories using routine patient samples from different transplant types: Performance of automated immunoassays and comparability to tandem mass spectrometry"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","428"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Therapeutic Drug Monitoring"],["dc.bibliographiccitation.lastpage","433"],["dc.bibliographiccitation.volume","30"],["dc.contributor.author","Brandhorst, Gunnar"],["dc.contributor.author","Marquet, Pierre"],["dc.contributor.author","Liebisch, Gerhard"],["dc.contributor.author","Schmitz, Gerd"],["dc.contributor.author","Coffing, Mary Jane"],["dc.contributor.author","Domke, Ingrid"],["dc.contributor.author","Streit, Frank"],["dc.contributor.author","Luthe, Hilmar"],["dc.contributor.author","Oellerich, Michael"],["dc.contributor.author","Shaw, Leslie M."],["dc.date.accessioned","2021-06-01T10:46:58Z"],["dc.date.available","2021-06-01T10:46:58Z"],["dc.date.issued","2008"],["dc.description.abstract","The performance characteristics of a new inosine monophosphate dehydrogenase inhibition assay for the quantification of total mycophenolic acid (MPA) in plasma (Roche Diagnostics) were assessed in a multicenter evaluation. Validation data were collected from four institutions. Within-run and total imprecision were acceptable (n = 21 for each of 7 materials, coefficients of variation ranging 0.7-9.6%). The lower limit of quantification was 0.31 mg/L. The assay was linear from 0.31 to 15.0 mg/L. Method comparison with validated high-performance liquid chromatography with ultraviolet light or liquid chromatography tandem mass spectrometry methods showed good agreement (coefficients of correlation 0.974-0.994, slopes 1.01-1.17, intercepts -0.17 to 0.06). There was no difference found between results from different transplant types (cardiac vs. renal) or comedications (cyclosporine vs. tacrolimus). The recovery of samples from a proficiency testing scheme was acceptable. The cross-reactivity of AcMPAG, an in vitro active metabolite of MPA, was examined by adding AcMPAG to a pool of patient samples and subsequent quantification. MPA overestimation by AcMPAG cross-reactivity was found to be low (< 5%). Thus, this interference is expected to be clinically irrelevant. In conclusion, the Roche Total MPA assay is a promising alternative for MPA quantification where chromatographic methods are not available."],["dc.identifier.doi","10.1097/FTD.0b013e31817fd590"],["dc.identifier.isi","000258114900004"],["dc.identifier.pmid","18641549"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85437"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","0163-4356"],["dc.title","Multicenter Evaluation of a New Inosine Monophosphate Dehydrogenase Inhibition Assay for Quantification of Total Mycophenolic Acid in Plasma"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Therapeutic Drug Monitoring"],["dc.bibliographiccitation.volume","29"],["dc.contributor.author","Brandhorst, Gunnar"],["dc.contributor.author","Streit, Frank"],["dc.contributor.author","Goetze, Sandra"],["dc.contributor.author","Rhode, Karl-Heinz"],["dc.contributor.author","Engelmayer, Jutta."],["dc.contributor.author","Luthe, Hilmar"],["dc.contributor.author","Oellerich, Michael"],["dc.date.accessioned","2018-11-07T11:00:30Z"],["dc.date.available","2018-11-07T11:00:30Z"],["dc.date.issued","2007"],["dc.format.extent","512"],["dc.identifier.isi","000248359200179"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50933"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","10th International Congress of Therapeutic Drug Monitoring and Clinical Toxicology"],["dc.relation.eventlocation","Nice, FRANCE"],["dc.relation.issn","0163-4356"],["dc.title","A new IMPDH tnhibition assay for the quantification of mycophenolic acid on the roche cobas c 501 analyzer compared to liquid chromatography tandem mass spectrometry"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Clinical Chemistry"],["dc.bibliographiccitation.volume","51"],["dc.contributor.author","Domke, I."],["dc.contributor.author","Engelmayer, J."],["dc.contributor.author","Langmann, T."],["dc.contributor.author","Liebisch, Gerhard"],["dc.contributor.author","Streit, Frank"],["dc.contributor.author","Luthe, Hilmar"],["dc.contributor.author","Dorn, A."],["dc.contributor.author","Schmitz, G."],["dc.contributor.author","Oellerich, M."],["dc.date.accessioned","2018-11-07T08:35:50Z"],["dc.date.available","2018-11-07T08:35:50Z"],["dc.date.issued","2005"],["dc.format.extent","A148"],["dc.identifier.isi","000229452500479"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18169"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Clinical Chemistry"],["dc.publisher.place","Washington"],["dc.relation.conference","57th Annual Meeting of the American-Association-for-Clinical-Chemistry"],["dc.relation.eventlocation","Orlando, FL"],["dc.relation.issn","0009-9147"],["dc.title","Measurement of total and free mycophenolic acid with new enzyme receptor methods on COBAS INTEGRA systems"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Clinical Chemistry"],["dc.bibliographiccitation.volume","52"],["dc.contributor.author","Domke, I."],["dc.contributor.author","Vukovich, T."],["dc.contributor.author","Engelmayer, J."],["dc.contributor.author","Kheradmand, M."],["dc.contributor.author","Luthe, Hilmar"],["dc.contributor.author","Shipkova, Maria"],["dc.contributor.author","Streit, Frank"],["dc.contributor.author","Oellerich, M."],["dc.contributor.author","Wieland, Eberhard"],["dc.date.accessioned","2018-11-07T09:44:06Z"],["dc.date.available","2018-11-07T09:44:06Z"],["dc.date.issued","2006"],["dc.format.extent","A61"],["dc.identifier.isi","000237925900187"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/34324"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Clinical Chemistry"],["dc.publisher.place","Washington"],["dc.relation.conference","58th Annual Meeting of the American-Association-of-Clinical-Chemistry"],["dc.relation.eventlocation","Chicago, IL"],["dc.relation.issn","0009-9147"],["dc.title","Comparability between automated immunoassays and LC-MS/MS for tacrolimus determination using routine patient samples"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Clinical Chemistry"],["dc.bibliographiccitation.volume","53"],["dc.contributor.author","Binder, L."],["dc.contributor.author","Streit, Frank"],["dc.contributor.author","Engelmayer, J."],["dc.contributor.author","Goetze, S."],["dc.contributor.author","Luthe, Hilmar"],["dc.contributor.author","Budde, K."],["dc.contributor.author","Beckebaum, S."],["dc.contributor.author","Doll, S."],["dc.contributor.author","Oellerich, M."],["dc.date.accessioned","2018-11-07T11:01:40Z"],["dc.date.available","2018-11-07T11:01:40Z"],["dc.date.issued","2007"],["dc.format.extent","A88"],["dc.identifier.isi","000246843000278"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51200"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Clinical Chemistry"],["dc.publisher.place","Washington"],["dc.relation.conference","59th Annual Meeting of the American-Association-for-Clinical-Chemistry"],["dc.relation.eventlocation","San Diego, CA"],["dc.relation.issn","0009-9147"],["dc.title","Comparison of the ADVIA centaur (R) cyclosporine assay with tandem mass spectrometry (LC-MS/MS)"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Clinical Chemistry"],["dc.bibliographiccitation.volume","53"],["dc.contributor.author","Brandhorst, Gunnar"],["dc.contributor.author","Streit, Frank"],["dc.contributor.author","Goetze, S."],["dc.contributor.author","Rhode, K."],["dc.contributor.author","Engelmayer, J."],["dc.contributor.author","Luthe, Hilmar"],["dc.contributor.author","Oellerich, M."],["dc.date.accessioned","2018-11-07T11:01:41Z"],["dc.date.available","2018-11-07T11:01:41Z"],["dc.date.issued","2007"],["dc.format.extent","A96"],["dc.identifier.isi","000246843000303"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51201"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Clinical Chemistry"],["dc.publisher.place","Washington"],["dc.relation.conference","59th Annual Meeting of the American-Association-for-Clinical-Chemistry"],["dc.relation.eventlocation","San Diego, CA"],["dc.relation.issn","0009-9147"],["dc.title","Quantification of mycophenolic acid by an optimized LC-MS/MS method compared to a new IMPDH inhibition assay on the cobas C 501 analyzer"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Clinical Chemistry"],["dc.bibliographiccitation.volume","54"],["dc.contributor.author","van Gelder, Tenn"],["dc.contributor.author","Domke, I."],["dc.contributor.author","Streit, Frank"],["dc.contributor.author","Koeger, R."],["dc.contributor.author","Luthe, Hilmar"],["dc.contributor.author","Oellerich, M."],["dc.date.accessioned","2018-11-07T11:14:18Z"],["dc.date.available","2018-11-07T11:14:18Z"],["dc.date.issued","2008"],["dc.format.extent","A15"],["dc.identifier.isi","000256325700044"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54094"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Clinical Chemistry"],["dc.publisher.place","Washington"],["dc.relation.conference","60th Annual Meeting of the American-Association-for-Clinical-Chemistry"],["dc.relation.eventlocation","Washington, DC"],["dc.relation.issn","0009-9147"],["dc.title","Clinical utility of a new enzymatic assay for determination of mycophenolic acid in comparison with an optimized LC-MS/MS method"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","378"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Clinical Biochemistry"],["dc.bibliographiccitation.lastpage","386"],["dc.bibliographiccitation.volume","39"],["dc.contributor.author","Wilson, Dawn M."],["dc.contributor.author","Johnston, F."],["dc.contributor.author","Holt, D."],["dc.contributor.author","Moreton, M."],["dc.contributor.author","Engelmayer, J."],["dc.contributor.author","Gaulier, J. M."],["dc.contributor.author","Luthe, Hilmar"],["dc.contributor.author","Marquet, Pierre"],["dc.contributor.author","Moscato, D."],["dc.contributor.author","Oellerich, M."],["dc.contributor.author","Mosso, R."],["dc.contributor.author","Streit, Frank"],["dc.contributor.author","Brunet, M."],["dc.contributor.author","Fillee, C."],["dc.contributor.author","Schmid, R."],["dc.contributor.author","Wallemacq, P."],["dc.contributor.author","Barnes, G."],["dc.date.accessioned","2018-11-07T10:00:59Z"],["dc.date.available","2018-11-07T10:00:59Z"],["dc.date.issued","2006"],["dc.description.abstract","Objectives: This study evaluated the analytical characteristics of the new Abbott microparticle enzyme immunoassay (MEIA) for sirolimus. Design and methods: The protocol consisted of nine sections: evaluation of antibody specificity, linearity, detection limit, quantification limit, endogenous interferents, exogenous interferents, precision, proficiency testing panel, and method comparison. Results: The mean analytical detection limit was 0.68 mu g/L. The sirolimus concentration corresponding to a total CV of 20% was 1.5 mu g/L. Linearity of response was demonstrated across the dynamic range of the assay. Total precision (CVs) at QC control levels from 5 to 22 mu g/L ranged from 5.7 to 12.6%. Assay standardization was found to be in good agreement with LC/MS/MS as compared with target values for spiked sirolimus proficiency samples from an international sirolimus proficiency testing program. Good correlations (R values) of the immunoassay were observed in comparisons to LC/MS/MS. R values tended to be lower in comparisons with LC/UV methods. Across both LC-based methods and all study sites, there was approximately 25% overall positive slope bias due to cross reactivity of the MEIA antibody to metabolites of sirolimus. The assay cross-reactivity to metabolites of sirolimus parent drug ranged from 6 to 63%. Assay interferences were minimal with the exception of hematocrit, which presented a negative relationship to measured sirolimus concentration. Conclusions: The MEIA demonstrated acceptable analytical characteristics for use for routine monitoring of sirolimus immunosuppressive therapy, and is a viable alternative to HPLC-based methods for sirolimus monitoring. (c) 2006 Published by The Canadian Society of Clinical Chemists."],["dc.identifier.doi","10.1016/j.clinbiochem.2006.01.017"],["dc.identifier.isi","000237378300010"],["dc.identifier.pmid","16545357"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37923"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0009-9120"],["dc.title","Multi-center evaluation of analytical performance of the microparticle enzyme immunoassay for sirolimus"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]