Hermann, K.-P.

[["dc.bibliographiccitation.firstpage","258"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","European Journal of Radiology"],["dc.bibliographiccitation.lastpage","265"],["dc.bibliographiccitation.volume","72"],["dc.contributor.author","Schulz-Wendtland, R."],["dc.contributor.author","Fuchsjaeger, M."],["dc.contributor.author","Wacker, T."],["dc.contributor.author","Hermann, K.-P."],["dc.date.accessioned","2018-11-07T11:22:33Z"],["dc.date.available","2018-11-07T11:22:33Z"],["dc.date.issued","2009"],["dc.description.abstract","Digital mammography has increasingly replaced conventional film-screen mammography and has become the gold standard in combination with soft copy reading in diagnostic as well as screening settings. Large international multi-center trials were able to demonstrate at least equivalence and for some aspects superiority of digital over conventional mammography with regard to detectability of breast cancer, especially in pre/perimenopausal women, women younger than 50 years and generally in dense breasts. Especially the experienced reader may benefit form CAD with an increase of specificity. Additionally digital mammography offers options of advanced processing such as digital tomosynthesis and contrast enhanced mammography. The future of breast imaging will be fusion of different imaging systems (hybrid systems). (C) 2009 Elsevier Ireland Ltd. All rights reserved"],["dc.identifier.doi","10.1016/j.ejrad.2009.05.052"],["dc.identifier.isi","000272787100011"],["dc.identifier.pmid","19592186"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56020"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Ireland Ltd"],["dc.relation.issn","0720-048X"],["dc.title","Digital mammography: An update"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","716"],["dc.bibliographiccitation.issue","981"],["dc.bibliographiccitation.journal","British Journal of Radiology"],["dc.bibliographiccitation.lastpage","723"],["dc.bibliographiccitation.volume","82"],["dc.contributor.author","Marten, Katharina"],["dc.contributor.author","Dullin, Christian"],["dc.contributor.author","Machann, W."],["dc.contributor.author","Schmid, J. S."],["dc.contributor.author","Das, M."],["dc.contributor.author","Hermann, K.-P."],["dc.contributor.author","Engelke, C."],["dc.date.accessioned","2018-11-07T11:24:35Z"],["dc.date.available","2018-11-07T11:24:35Z"],["dc.date.issued","2009"],["dc.description.abstract","This study evaluates the accuracy and reproducibility of an experimental flat-panel-detector-based CT scanner (fp-CT) in comparison with those of a 64-slice multidetector row CT (MDCT) in automated pulmonary nodule volumetry. An anthropomorphic chest phantom with 31 spherical nodules (nodule diameters of 2.94-10.01 mm; volumes of 13.24-524.97 mm(3)) was scanned both with an amorphous silicon-based fp-CT scanner, using various tube current and kilovoltage settings, and with a conventional MDCT scanner. Automated nodule volumetry was performed using dedicated software. CT image data were evaluated twice by two independent radiologists. Intra-and inter-observer variations of volumetric measurements were determined and tested using the Kruskal-Wallis test and analysis of variance (fn-ANOVA). The percentage measurement errors (PME) were calculated and differences tested using Wilcoxon signed ranks and Friedman tests. Intraobserver variation was significantly higher for MDCT than for fp-CT (range: p=0.043-0.045). The measured nodule volumes were significantly greater on fp-CT than on MDCT scans (p<0.001). The PME was significantly greater in fp-CT than in MDCT scans (PME range, 12.35-13.35% for fp-CT scan protocols and 16.87-19.02% for MDCT scan protocols; p<0.0001). The PME increased significantly with reduction of nodule size, and this increase was significantly higher on MDCT than on fp-CT scans (p=0.0001). The absolute PME was significantly different for nodules of less than 5 mm in diameter (p=0.0001-0.0033) than for larger nodules. Flat-panel-detector-based CT has advantages over MDCT in accurately determining the volume of pulmonary nodules below 5 mm in diameter."],["dc.identifier.doi","10.1259/bjr/40733553"],["dc.identifier.isi","000271037700003"],["dc.identifier.pmid","19332516"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56439"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","British Inst Radiology"],["dc.relation.issn","0007-1285"],["dc.title","Comparison of flat-panel-detector-based CT and multidetector-row CT in automated volumetry of pulmonary nodules using an anthropomorphic chest phantom"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","96"],["dc.bibliographiccitation.journal","Annals of the Rheumatic Diseases"],["dc.bibliographiccitation.lastpage","97"],["dc.bibliographiccitation.volume","66"],["dc.contributor.author","Song, In-Ho"],["dc.contributor.author","AIthoff, C."],["dc.contributor.author","Hermann, K."],["dc.contributor.author","Scheel, A."],["dc.contributor.author","Knetsch, Torsten"],["dc.contributor.author","Burmester, Gerd-Ruediger"],["dc.contributor.author","Backhaus, M."],["dc.date.accessioned","2018-11-07T11:00:49Z"],["dc.date.available","2018-11-07T11:00:49Z"],["dc.date.issued","2007"],["dc.identifier.isi","000253101100306"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51013"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","B M J Publishing Group"],["dc.publisher.place","London"],["dc.relation.conference","Annual European Congress of Rheumatology (EULAR 2007)"],["dc.relation.eventlocation","Barcelona, SPAIN"],["dc.relation.issn","0003-4967"],["dc.title","Comparison of contrast-enhanced ulthasunography (CE-US) and MR-imaging (CE-MRI) in monitoring the efficacy of a bradykinin receptor-2 antagonist in painful knee osteoarthritis (OA)"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","492"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN"],["dc.bibliographiccitation.lastpage","496"],["dc.bibliographiccitation.volume","179"],["dc.contributor.author","Schulz-Wendtland, R."],["dc.contributor.author","Hermann, K.-P."],["dc.contributor.author","Wenkel, E."],["dc.contributor.author","Adamietz, B."],["dc.contributor.author","Lell, M."],["dc.contributor.author","Böhner, C."],["dc.contributor.author","Uder, M."],["dc.contributor.author","Bautz, W. A."],["dc.date.accessioned","2018-11-07T11:03:02Z"],["dc.date.available","2018-11-07T11:03:02Z"],["dc.date.issued","2007"],["dc.description.abstract","Purpose: Evaluation of the diagnostic value of breast specimen imaging with a digital mammographic system using a detector system with changeable pixel size compared to standard mode imaging in different monitor display modes. Materials and Methods: Using the digital mammographic system SenoScan (Fischer Imaging, Denver, USA), 50 diagnostic breast specimens with microcalcifications were visualized in both standard mode (pixel size 54 pm) and high resolution mode (pixel size 27 pm). The resulting radiographs were displayed 1:1 on a monitor. Standard mode images (pixel size 54 mu m) were additionally displayed in a 2:1 mode. A total of 5 readers with different mammographic experience analyzed the type of the microcalcifications on the basis of the different display modes. The images were presented randomly. The findings were subsequently compared to the histology. Results: The high resolution mode yielded slightly but not significantly better results than the standard mode on average for all 5 readers. Compared to a sensitivity of 80% and a specificity of 72% (PPV=74%, NPV=78%) in the standard mode, the high resolution mode provided a sensitivity of 86% and a specificity of 74% (PPV = 77%, NPV = 83%). The standard mode images on a 2:1 monitor display yielded 84% and 74% (PPV = 76%, NPV = 82%). Conclusion: The high resolution mode did not significantly increase the sensitivity and specificity of the microcalcification reading. A similar improvement was achieved by the 2:1 display mode, i.e. digital monitor zooming. For the clinical situation this means that there is no diagnostic advantage from using a high resolution target view with this mammographic system."],["dc.identifier.doi","10.1055/s-2007-962980"],["dc.identifier.isi","000246689800006"],["dc.identifier.pmid","17436183"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51524"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1438-9029"],["dc.title","Comparing the clinical value of spot view mammography with reduced pixel size to monitor zooming by reporting microcalcifications in digital mammography"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","126"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Der Radiologe"],["dc.bibliographiccitation.lastpage","129"],["dc.bibliographiccitation.volume","51"],["dc.contributor.author","Schulz-Wendtland, R."],["dc.contributor.author","Hermann, K.-P."],["dc.contributor.author","Adamietz, B."],["dc.contributor.author","Meier-Meitinger, M."],["dc.contributor.author","Wenkel, E."],["dc.contributor.author","Lell, M."],["dc.contributor.author","Anders, K."],["dc.contributor.author","Uder, M."],["dc.date.accessioned","2018-11-07T08:59:58Z"],["dc.date.available","2018-11-07T08:59:58Z"],["dc.date.issued","2011"],["dc.description.abstract","Purpose. The aim of this retrospective clinical study was to compare the diagnostic accuracy of the novel 50 mu m FFDM (full-field digital mammography) system (DR) with an established 70 mu m system (DR) in the differential diagnosis between benign and malignant clusters of microcalcification (n=50) (BI-RADS (TM) T classification 4/5) and to assess the possible incremental value of the 50 mu m pixel-pitch on specificity. Material and methods. From March 2009 to September 2009, 50 patients underwent full-field digital mammography (FFDM) (detector resolution 70 mu m) (Novation, Siemens, Erlangen, Germany). As there were suspicious signs of microcalcification classified with BI-RADS (TM) 4/5 after diagnosis and preoperative wire localization, control images were made with the new FFDM system (detector: resolution 50 mu m) (Amulet, Fujifilm, Tokyo, Japan) with the same exposure parameters. The diagnosis was determined after the operation by five radiologists with different experience in digital mammography from randomly distributed mediolateral views (monitor reading) whose results were correlated with the final histology of all lesions. Results. Histopathology revealed 19 benign and 31 malignant lesions in 50 patients after open biopsy. The results of the five readers showed a higher sensitivity of the new FFDM system (80.0%) in the ability to recognize malignant microcalcification in comparison to the established system (74.8%). The specificity (75.8 versus 71.6%) was slightly higher for the new system but hese results were not statistically significant (p<0.001). Considering the diagnostic accuracy, the new system (detector: resolution 50 mu m) was also slightly superior to the well-known system (detector: resolution 70 mu m) (80.1% versus 76.4%). Conclusions. Our study has shown that the new full-field digital mammography system using the novel detector compared with the already established FFDM system with respect to the assessment of microcalcification is at least equivalent."],["dc.identifier.doi","10.1007/s00117-010-2078-6"],["dc.identifier.isi","000289488700008"],["dc.identifier.pmid","21069511"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24033"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-2102"],["dc.relation.issn","0033-832X"],["dc.title","Comparison of dignity determination of mammographic microcalcification with two systems for digital full-field mammography with different detector resolution. A retrospective clinical study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","256"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Der Radiologe"],["dc.bibliographiccitation.lastpage","260"],["dc.bibliographiccitation.volume","42"],["dc.contributor.author","Hermann, K.-P."],["dc.contributor.author","Funke, M."],["dc.contributor.author","Grabbe, Eckhard"],["dc.date.accessioned","2018-11-07T10:31:03Z"],["dc.date.available","2018-11-07T10:31:03Z"],["dc.date.issued","2002"],["dc.description.abstract","The establishment of digital mammography systems constitutes a slow process,the reason for this being the general need of particular image quality in mammography. This article provides an overview of the physical basis of digital mammography with high image quality and dose as low as reasonably achievable. The trade-off of high contrast resolution and effective quantum efficiency of the imaging system on the one hand, and the demand of high spatial resolution or very small pixel size on the other hand is discussed. The actual status of the available digital detector technology for mammography is described. The digital systems presently available are superior to conventional screen-film mammographic systems with respect to contrast resolution. An outlook on possible further developments in the field of digital mammography is presented."],["dc.identifier.doi","10.1007/s00117-002-0734-1"],["dc.identifier.isi","000175618200002"],["dc.identifier.pmid","12063731"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44008"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0033-832X"],["dc.title","Physical aspects of digital mammography technology"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","478"],["dc.bibliographiccitation.issue","907"],["dc.bibliographiccitation.journal","British Journal of Radiology"],["dc.bibliographiccitation.lastpage","482"],["dc.bibliographiccitation.volume","76"],["dc.contributor.author","Obenauer, Silvia"],["dc.contributor.author","Hermann, K.-P."],["dc.contributor.author","Grabbe, Eckhard"],["dc.date.accessioned","2018-11-07T10:37:52Z"],["dc.date.available","2018-11-07T10:37:52Z"],["dc.date.issued","2003"],["dc.description.abstract","The aim of this study was to evaluate the potential for radiation dose reduction by using other beam qualities in full-field digital mammography (FFDM) compared with screen-film mammography (SFM). FFDM was performed using an amorphous silicon detector with a caesium iodide scintillator layer (Senographe 2000D, GE, Milwaukee, USA). SFM was performed using a state-of-the-art conventional system (Senographe DMR, GE, Milwaukee, USA) with a dedicated screen-film combination. An anthropomorphic breast phantom with superimposed microcalcifications (50-200 mum) was used to evaluate the detectability of microcalcifications. Contact mammograms and magnification views (m=1.8) performed with both the digital and the screen-film system were compared. Images were exposed automatically. Molybdenum/Molybdenum (Mo/Mo) anode-filter combination, 28 kVp and 63 mAs were selected by the automatic optimization of parameters (AOP) of the conventional system. This exposure protocol (protocol A) was also used as baseline for the digital system. Dose reduction in digital mammography was achieved by using protocol B with Mo/Rh and 31 kVp and protocol C with Rh/Rh and 32 kVp. The detectability of microcalcifications was assessed by 3 experienced readers with a confidence level ranging from 1 to 5. A receiver operating characteristic (ROC) analysis was performed. In protocol A the area under the ROC-curve (A(z)) for contact views performed by the screen-film system was 0.64 and for those performed with the FFDM system 0.68. The A(z) values were 0.74 in protocol B and 0.65 in protocol C for the digital system. For the conventional and digital magnification views A(z) values were 0.71 and 0.79, respectively. For protocol B the A(z) value was 0.81 and for protocol C it was 0.76. There is no statistically significant difference in the A(z) values for the different protocols in digital mammography and no significant difference from the screen-film system. A potential for dose reduction by using other beam qualities seems to be possible with this digital system."],["dc.identifier.doi","10.1259/bjr/67597156"],["dc.identifier.isi","000184227200009"],["dc.identifier.pmid","12857708"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/45672"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0007-1285"],["dc.title","Dose reduction in full-field digital mammography: an anthropomorphic breast phantom study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","359"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Der Radiologe"],["dc.bibliographiccitation.lastpage","365"],["dc.bibliographiccitation.volume","41"],["dc.contributor.author","Grabbe, Eckhard"],["dc.contributor.author","Fischer, U."],["dc.contributor.author","Funke, M."],["dc.contributor.author","Hermann, K.-P."],["dc.contributor.author","Obenauer, Silvia"],["dc.contributor.author","Baum, F."],["dc.date.accessioned","2018-11-07T09:15:05Z"],["dc.date.available","2018-11-07T09:15:05Z"],["dc.date.issued","2001"],["dc.description.abstract","To evaluate the digital technique for screening mammography various experimental studies and clinical examinations were performed by using direct full-field digital mammography (FFDM). The findings concerning the detectability and characterization of microcalcifications and soft tissue masses as well as the radiation exposure were compared to the state-of-the-art conventional screen-film mammography (SFM). The results of these studies revealed a high performance of the digital images, which are at least equivalent to the conventional images, whereas digital spot views were significantly superior to conventional ones particually in the detection of microcalcifications. This was especially true, when the potential of post-processing was used. In addition, the sensitivity of FFDM should be increased, if computer-aided-diagnosis (CAD) is available. Furthermore, the patient radiation dose can be significantly reduced. Additional advantages are quick and easy handling, efficient data transfer and digital archiving. Thus, FFDM will become an important tool in screening mammography."],["dc.identifier.doi","10.1007/s001170051014"],["dc.identifier.isi","000168405600006"],["dc.identifier.pmid","11388057"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27590"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0033-832X"],["dc.title","Value and importance of full-field digital mammography (FFDM) for screening"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1052"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN"],["dc.bibliographiccitation.lastpage","1056"],["dc.bibliographiccitation.volume","172"],["dc.contributor.author","Obenauer, Silvia"],["dc.contributor.author","Hermann, K.-P."],["dc.contributor.author","Schorn, C."],["dc.contributor.author","Fischer, U."],["dc.contributor.author","Grabbe, Eckhard"],["dc.date.accessioned","2018-11-07T10:58:00Z"],["dc.date.available","2018-11-07T10:58:00Z"],["dc.date.issued","2000"],["dc.description.abstract","Objectives: The study compares contrast-detail and microcalcification detectability of a full-field digital mammography (FFDM) to a state-of-the-art conventional screen-film mammography (SFM) by using different doses in the digital system. Materials and Methods: The investigations were performed with an FFDM (Senographe 2000 D, GEMS) and an SFM system (Senographe DMR, GEMS) using a contrast-detail mammography phantom (CDMAM) and an anthropomorphic breast phantom with superimposed microcalcifications. The digital detector was exposed with standard dose of SFM and with a dose reduction of up to 75%. Contrast-detail curves and correct observation ratio (COR) were performed for the CDMAM phantom. ROC analysis with a confidence level ranging from 1 to 5 was done with the results of the anthropomorphic phantom. Results: Digital mammography with the same dose revealed at least an equivalent or even higher detectability rate than conventional mammography, COR could be increased at about 10-25%. The ROC analysis yielded better results for the FFDM system. The same lesion detectability in digital mammography as in the conventional method was reached at a dose reduction of about 25%, concerning spot views even at higher reduction. Dose reduction in the anthropomorphic phantom resulted in a linear loss of detectability. The same detectability as in conventional mammography was reached, however, by a dose reduction of about 50%. Conclusion: The results suggest that FFDM is at least equivalent to or - as far as spot views are concerned - superior to conventional SFM concerning the detectability of simulated lesions. Thus, a potential of dose reduction is suggested."],["dc.identifier.doi","10.1055/s-2000-9222"],["dc.identifier.isi","000166208200017"],["dc.identifier.pmid","11199434"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50382"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Georg Thieme Verlag Kg"],["dc.relation.issn","1438-9029"],["dc.title","Full-field digital mammography: Dose-dependent detectability of simulated breast lesions"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","255"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Der Radiologe"],["dc.bibliographiccitation.lastpage","263"],["dc.bibliographiccitation.volume","45"],["dc.contributor.author","Schulz-Wendtland, R."],["dc.contributor.author","Hermann, K.-P."],["dc.contributor.author","Bautz, W."],["dc.date.accessioned","2018-11-07T11:21:57Z"],["dc.date.available","2018-11-07T11:21:57Z"],["dc.date.issued","2005"],["dc.description.abstract","Digital mammography is the technology of the future in breast diagnosis. This article provides an overview of all digital mammography units admitted by the Food and Drug Administration (FDA), results of clinical studies, soft copy reading, CAD (computer aided detection), and presents an overview on possible further developments. It is obvious that clinical results are equivalent to conventional screen film mammography and digital mammography."],["dc.identifier.doi","10.1007/s00117-005-1175-4"],["dc.identifier.isi","000228610100005"],["dc.identifier.pmid","15744483"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/55893"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0033-832X"],["dc.title","Digital mammography. Results of clinical studies"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]