Ehrenreich, Ludwig

[["dc.bibliographiccitation.firstpage","90"],["dc.bibliographiccitation.journal","Brain Research"],["dc.bibliographiccitation.lastpage","95"],["dc.bibliographiccitation.volume","1148"],["dc.contributor.author","Jürgens, Uwe"],["dc.contributor.author","Ehrenreich, Ludwig"],["dc.date.accessioned","2022-10-06T13:33:00Z"],["dc.date.available","2022-10-06T13:33:00Z"],["dc.date.issued","2007"],["dc.identifier.doi","10.1016/j.brainres.2007.02.020"],["dc.identifier.pii","S000689930700409X"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115518"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0006-8993"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","The descending motorcortical pathway to the laryngeal motoneurons in the squirrel monkey"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","40"],["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Neuroscience"],["dc.bibliographiccitation.lastpage","9"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Hammerschmidt, Kurt"],["dc.contributor.author","Reisinger, Ellen"],["dc.contributor.author","Westekemper, Katharina"],["dc.contributor.author","Ehrenreich, Ludwig"],["dc.contributor.author","Strenzke, Nicola"],["dc.contributor.author","Fischer, Julia"],["dc.date.accessioned","2017-09-07T11:47:41Z"],["dc.date.available","2017-09-07T11:47:41Z"],["dc.date.issued","2012"],["dc.description.abstract","BACKGROUND:Transgenic mice have become an important tool to elucidate the genetic foundation of the human language faculty. While learning is an essential prerequisite for the acquisition of human speech, it is still a matter of debate whether auditory learning plays any role in the development of species-specific vocalizations in mice. To study the influence of auditory input on call development, we compared the occurrence and structure of ultrasonic vocalizations from deaf otoferlin-knockout mice, a model for human deafness DFNB9, to those of hearing wild-type and heterozygous littermates.RESULTS:We found that the occurrence and structure of ultrasonic vocalizations recorded from deaf otoferlin-knockout mice and hearing wild-type and heterozygous littermates do not differ. Isolation calls from 16 deaf and 15 hearing pups show the same ontogenetic development in terms of the usage and structure of their vocalizations as their hearing conspecifics. Similarly, adult courtship 'songs' produced by 12 deaf and 16 hearing males did not differ in the latency to call, rhythm of calling or acoustic structure.CONCLUSION:The results indicate that auditory experience is not a prerequisite for the development of species-specific vocalizations in mice. Thus, mouse models are of only limited suitability to study the evolution of vocal learning, a crucial component in the development of human speech. Nevertheless, ultrasonic vocalizations of mice constitute a valuable readout in studies of the genetic foundations of social and communicative behavior."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2012"],["dc.identifier.doi","10.1186/1471-2202-13-40"],["dc.identifier.gro","3150690"],["dc.identifier.pmid","22533376"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7598"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7474"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","final"],["dc.relation.issn","1471-2202"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.subject","DFNB9; Evolution; Language; Mice; Ontogeny; Otoferlin; Speech; Vocal learning"],["dc.title","Mice do not require auditory input for the normal development of their ultrasonic vocalizations"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","no"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","331"],["dc.bibliographiccitation.issue","1-2"],["dc.bibliographiccitation.journal","Behavioural Brain Research"],["dc.bibliographiccitation.lastpage","336"],["dc.bibliographiccitation.volume","151"],["dc.contributor.author","Tammer, Roland"],["dc.contributor.author","Ehrenreich, Ludwig"],["dc.contributor.author","Jürgens, Uwe"],["dc.date.accessioned","2022-10-06T13:32:58Z"],["dc.date.available","2022-10-06T13:32:58Z"],["dc.date.issued","2004"],["dc.identifier.doi","10.1016/j.bbr.2003.09.008"],["dc.identifier.pii","S0166432803003152"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115504"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0166-4328"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Telemetrically recorded neuronal activity in the inferior colliculus and bordering tegmentum during vocal communication in squirrel monkeys (Saimiri sciureus)"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","605"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Behavioural Brain Research"],["dc.bibliographiccitation.lastpage","610"],["dc.bibliographiccitation.volume","136"],["dc.contributor.author","Jürgens, Uwe"],["dc.contributor.author","Ehrenreich, Ludwig"],["dc.contributor.author","De Lanerolle, Nihal C"],["dc.date.accessioned","2022-10-06T13:33:49Z"],["dc.date.available","2022-10-06T13:33:49Z"],["dc.date.issued","2002"],["dc.identifier.doi","10.1016/S0166-4328(02)00202-4"],["dc.identifier.pii","S0166432802002024"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115740"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0166-4328"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","2-Deoxyglucose uptake during vocalization in the squirrel monkey brain"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","221"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Neuroscience Methods"],["dc.bibliographiccitation.lastpage","229"],["dc.bibliographiccitation.volume","153"],["dc.contributor.author","Tammer, Roland"],["dc.contributor.author","Ehrenreich, L."],["dc.contributor.author","Boretius, Susann"],["dc.contributor.author","Watanabe, Takashi"],["dc.contributor.author","Frahm, Jens"],["dc.contributor.author","Michaelis, Thomas"],["dc.date.accessioned","2017-09-07T11:45:31Z"],["dc.date.available","2017-09-07T11:45:31Z"],["dc.date.issued","2005"],["dc.description.abstract","Knowledge of the precise position of recording microelectrodes within the brain of a non-human primate is essential for a reliable exploration of very small anatomic structures. This work demonstrates the compatibility of a newly developed glass-guided microelectrode design and microfeed equipment with high-resolution 3D magnetic resonance imaging (MRI). T1- and T2-weighted images allow for the non-invasive visualization of chronically implanted microelectrodes within the brain stem of squirrel monkeys in vivo. Neural extracellular multi-unit recordings proved the functionality of the microelectrode before and after the use of 3D MRI suggesting the preservation of normal brain tissue at the tip of the electrode. Because histology confirmed the absence of lesions attributable to MRI, the approach offers an interactive monitoring during the course of neuroethological experiments. Consequently, MRI may become an in vivo alternative to common histological post mortem verifications of electrode tracks and hence may avoid the early sacrificing of primates after only a small number of experiments."],["dc.identifier.doi","10.1016/j.jneumeth.2005.10.018"],["dc.identifier.gro","3150378"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7136"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.relation.issn","0165-0270"],["dc.title","Compatibility of glass-guided recording microelectrodes in the brain stem of squirrel monkeys with high-resolution 3D MRI"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","339"],["dc.bibliographiccitation.issue","3-6"],["dc.bibliographiccitation.journal","Magnetic Resonance Materials in Physics, Biology and Medicine"],["dc.bibliographiccitation.lastpage","347"],["dc.bibliographiccitation.volume","17"],["dc.contributor.author","Boretius, S."],["dc.contributor.author","Natt, O."],["dc.contributor.author","Watanabe, T."],["dc.contributor.author","Tammer, R."],["dc.contributor.author","Ehrenreich, L."],["dc.contributor.author","Frahm, J."],["dc.contributor.author","Michaelis, T."],["dc.date.accessioned","2017-09-07T11:45:31Z"],["dc.date.available","2017-09-07T11:45:31Z"],["dc.date.issued","2004"],["dc.description.abstract","The purpose was to assess the potential of half Fourier diffusion-weighted single-shot STEAM MRI for diffusion tensor mapping of animal brain in vivo. A STEAM sequence with image acquisition times of about 500 ms was implemented at 2.35 T using six gradient orientations and b values of 200, 700, and 1200 s mm(-2). The use of half Fourier phase-encoding increased the signal-to-noise ratio by 45% relative to full Fourier acquisitions. Moreover, STEAM-derived maps of the relative anisotropy and main diffusion direction were completely free of susceptibility-induced signal losses and geometric distortions. Within measuring times of 3 h, the achieved resolution varied from 600x700x1000 microm3 for squirrel monkeys to 140x280x720 microm3 for mice. While in monkeys the accessible white matter fiber connections were comparable to those reported for humans, detectable fiber structures in mice focused on the corpus callosum, anterior commissure, and hippocampal fimbria. In conclusion diffusion-weighted single-shot STEAM MRI allows for in vivo diffusion tensor mapping of the brain of squirrel monkeys, rats, and mice without motion artifacts and susceptibility distortions."],["dc.identifier.doi","10.1007/s10334-004-0069-1"],["dc.identifier.gro","3150383"],["dc.identifier.pmid","15580374"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7141"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.issn","0968-5243"],["dc.subject","Magnetic resonance imaging; Diffusion-weighted imaging; Anisotropy; White matter; Animal brain"],["dc.title","In vivo diffusion tensor mapping of the brain of squirrel monkey, rat, and mouse using single-shot STEAM MRI"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]