Lange, Peter

[["dc.bibliographiccitation.firstpage","410"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Brain Sciences"],["dc.bibliographiccitation.volume","12"],["dc.contributor.affiliation","Konen, Franz Felix; 1Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany; konen.felix@mh-hannover.de (F.F.K.); wurster.ulrich@mh-hannover.de (U.W.); jendretzky.konstantin@mh-hannover.de (K.F.J.); gingele.stefan@mh-hannover.de (S.G.); moehn.nora@mh-hannover.de (N.M.); suehs.kurt-wolfram@mh-hannover.de (K.-W.S.); stangel.martin@mh-hannover.de (M.S.); skripuletz.thomas@mh-hannover.de (T.S.)"],["dc.contributor.affiliation","Lange, Peter; 2Department of Neurology, University Medical Center Göttingen (UMG), 37075 Göttingen, Germany; peter-la@med.uni-goettingen.de"],["dc.contributor.affiliation","Wurster, Ulrich; 1Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany; konen.felix@mh-hannover.de (F.F.K.); wurster.ulrich@mh-hannover.de (U.W.); jendretzky.konstantin@mh-hannover.de (K.F.J.); gingele.stefan@mh-hannover.de (S.G.); moehn.nora@mh-hannover.de (N.M.); suehs.kurt-wolfram@mh-hannover.de (K.-W.S.); stangel.martin@mh-hannover.de (M.S.); skripuletz.thomas@mh-hannover.de (T.S.)"],["dc.contributor.affiliation","Jendretzky, Konstantin Fritz; 1Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany; konen.felix@mh-hannover.de (F.F.K.); wurster.ulrich@mh-hannover.de (U.W.); jendretzky.konstantin@mh-hannover.de (K.F.J.); gingele.stefan@mh-hannover.de (S.G.); moehn.nora@mh-hannover.de (N.M.); suehs.kurt-wolfram@mh-hannover.de (K.-W.S.); stangel.martin@mh-hannover.de (M.S.); skripuletz.thomas@mh-hannover.de (T.S.)"],["dc.contributor.affiliation","Gingele, Stefan; 1Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany; konen.felix@mh-hannover.de (F.F.K.); wurster.ulrich@mh-hannover.de (U.W.); jendretzky.konstantin@mh-hannover.de (K.F.J.); gingele.stefan@mh-hannover.de (S.G.); moehn.nora@mh-hannover.de (N.M.); suehs.kurt-wolfram@mh-hannover.de (K.-W.S.); stangel.martin@mh-hannover.de (M.S.); skripuletz.thomas@mh-hannover.de (T.S.)"],["dc.contributor.affiliation","Möhn, Nora; 1Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany; konen.felix@mh-hannover.de (F.F.K.); wurster.ulrich@mh-hannover.de (U.W.); jendretzky.konstantin@mh-hannover.de (K.F.J.); gingele.stefan@mh-hannover.de (S.G.); moehn.nora@mh-hannover.de (N.M.); suehs.kurt-wolfram@mh-hannover.de (K.-W.S.); stangel.martin@mh-hannover.de (M.S.); skripuletz.thomas@mh-hannover.de (T.S.)"],["dc.contributor.affiliation","Sühs, Kurt-Wolfram; 1Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany; konen.felix@mh-hannover.de (F.F.K.); wurster.ulrich@mh-hannover.de (U.W.); jendretzky.konstantin@mh-hannover.de (K.F.J.); gingele.stefan@mh-hannover.de (S.G.); moehn.nora@mh-hannover.de (N.M.); suehs.kurt-wolfram@mh-hannover.de (K.-W.S.); stangel.martin@mh-hannover.de (M.S.); skripuletz.thomas@mh-hannover.de (T.S.)"],["dc.contributor.affiliation","Stangel, Martin; 1Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany; konen.felix@mh-hannover.de (F.F.K.); wurster.ulrich@mh-hannover.de (U.W.); jendretzky.konstantin@mh-hannover.de (K.F.J.); gingele.stefan@mh-hannover.de (S.G.); moehn.nora@mh-hannover.de (N.M.); suehs.kurt-wolfram@mh-hannover.de (K.-W.S.); stangel.martin@mh-hannover.de (M.S.); skripuletz.thomas@mh-hannover.de (T.S.)"],["dc.contributor.affiliation","Skripuletz, Thomas; 1Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany; konen.felix@mh-hannover.de (F.F.K.); wurster.ulrich@mh-hannover.de (U.W.); jendretzky.konstantin@mh-hannover.de (K.F.J.); gingele.stefan@mh-hannover.de (S.G.); moehn.nora@mh-hannover.de (N.M.); suehs.kurt-wolfram@mh-hannover.de (K.-W.S.); stangel.martin@mh-hannover.de (M.S.); skripuletz.thomas@mh-hannover.de (T.S.)"],["dc.contributor.affiliation","Schwenkenbecher, Philipp; 1Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, 30625 Hannover, Germany; konen.felix@mh-hannover.de (F.F.K.); wurster.ulrich@mh-hannover.de (U.W.); jendretzky.konstantin@mh-hannover.de (K.F.J.); gingele.stefan@mh-hannover.de (S.G.); moehn.nora@mh-hannover.de (N.M.); suehs.kurt-wolfram@mh-hannover.de (K.-W.S.); stangel.martin@mh-hannover.de (M.S.); skripuletz.thomas@mh-hannover.de (T.S.)"],["dc.contributor.author","Konen, Franz Felix"],["dc.contributor.author","Lange, Peter"],["dc.contributor.author","Wurster, Ulrich"],["dc.contributor.author","Jendretzky, Konstantin Fritz"],["dc.contributor.author","Gingele, Stefan"],["dc.contributor.author","Möhn, Nora"],["dc.contributor.author","Sühs, Kurt-Wolfram"],["dc.contributor.author","Stangel, Martin"],["dc.contributor.author","Skripuletz, Thomas"],["dc.contributor.author","Schwenkenbecher, Philipp"],["dc.date.accessioned","2022-04-01T10:02:04Z"],["dc.date.available","2022-04-01T10:02:04Z"],["dc.date.issued","2022"],["dc.date.updated","2022-04-08T08:24:49Z"],["dc.description.abstract","Background: Cerebrospinal fluid (CSF) samples from patients with non-inflammatory neurological diseases are used for control groups in biomarker studies. Since large amounts of CSF are withdrawn, patients with idiopathic intracranial hypertension (IIH) or normal pressure hydrocephalus (NPH) are especially suitable. The serially taken CSF portions are usually collected in different tubes. We aimed to investigate whether the later random choice of one of these tubes for CSF investigations might harbor the risk of different CSF protein findings due to the so-called ventriculo-lumbar CSF gradient. Methods: Patients with IIH (9) and NPH (7) were included. CSF was serially taken and collected in six tubes of 5 mL each. Concentrations and CSF-serum quotients of immunoglobulins, albumin and the virus-specific antibody index (AI) were determined in the first, fourth and sixth CSF fraction. Results: CSF immunoglobulin and albumin concentrations and CSF-serum protein quotients were significantly lower in the fourth and sixth CSF fraction compared with the first CSF fraction. Virus-specific AI did not significantly differ in the different CSF fractions. Conclusions: CSF protein analytics should be performed in the first CSF fraction in order to avoid different measurement results and achieve comparability within a control group and between different control and patient groups."],["dc.identifier.doi","10.3390/brainsci12030410"],["dc.identifier.pii","brainsci12030410"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/105817"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-530"],["dc.relation.eissn","2076-3425"],["dc.rights","Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."],["dc.title","The Influence of the Ventricular-Lumbar Gradient on Cerebrospinal Fluid Analysis in Serial Samples"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.subtype","original_ja"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Fluids and Barriers of the CNS"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Möhn, Nora"],["dc.contributor.author","Luo, Yi"],["dc.contributor.author","Skripuletz, Thomas"],["dc.contributor.author","Schwenkenbecher, Philipp"],["dc.contributor.author","Zerr, Inga"],["dc.contributor.author","Lange, Peter"],["dc.contributor.author","Stangel, Martin"],["dc.date.accessioned","2020-12-10T18:39:01Z"],["dc.date.available","2020-12-10T18:39:01Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1186/s12987-019-0148-3"],["dc.identifier.eissn","2045-8118"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16460"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77514"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Tau-protein concentrations are not elevated in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]