Becker, Anja

[["dc.bibliographiccitation.firstpage","1183"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Neuroscience"],["dc.bibliographiccitation.lastpage","1191"],["dc.bibliographiccitation.volume","167"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Sagvolden, T."],["dc.contributor.author","DasBanerjee, T."],["dc.contributor.author","Middleton, Frank A."],["dc.contributor.author","Faraone, Steven V."],["dc.contributor.author","Walaas, S. I."],["dc.contributor.author","Becker, A."],["dc.contributor.author","Rothenberger, A."],["dc.contributor.author","Bock, Nathalie"],["dc.date.accessioned","2018-11-07T08:42:20Z"],["dc.date.available","2018-11-07T08:42:20Z"],["dc.date.issued","2010"],["dc.description.abstract","The spontaneously hypertensive rat (SHR/NCrI) is a validated model of attention-deficit/hyperactivity disorder (ADHD) combined subtype, whereas a recently identified sub-strain of the Wistar Kyoto rat (WKY/NCrI) is a model of ADHD inattentive subtype. In this study, we first examined the expression of genes involved in dopamine signaling and metabolism in the dorsal striatum and ventral mesencephalon of these two rat strains, as well as three reference control strains (WKY/NHsd, WK/HanTac, and SD/NTac) using quantitative real time RT-PCR. Next, striatal dopamine transporter (DAT) density was determined by ligand binding assay in the two ADHD-like strains at different developmental stages and after methylphenidate treatment. In adult rats, the mRNA expression of DAT and tyrosine hydroxylase was elevated in SHR/NCrI and WKY/NCrI rats compared to control strains, with differences between SHR/NCrI and WKY/NCrI rats also evident. During normal development, changes of striatal DAT densities occurred in both strains with lower densities in WKY/NCrI compared to SHR/NCrI after day 25. Two-weeks methylphenidate treatment during different developmental stages was associated with decreased striatal DAT density in both rat strains compared to the non-treated rats with more pronounced effects followed prepubertal treatment. These results suggest differences in the pathophysiology of the combined versus the predominantly inattentive animal model of ADHD. Finally, treatment with methylphenidate might reduce elevated DAT levels more effectively in the combined subtype especially when applied before puberty. (C) 2010 IBRO. Published by Elsevier Ltd. All rights reserved."],["dc.identifier.doi","10.1016/j.neuroscience.2010.02.073"],["dc.identifier.isi","000277434800022"],["dc.identifier.pmid","20211696"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6332"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19675"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Pergamon-elsevier Science Ltd"],["dc.relation.issn","0306-4522"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","METHYLPHENIDATE NORMALIZES ELEVATED DOPAMINE TRANSPORTER DENSITIES IN AN ANIMAL MODEL OF THE ATTENTION-DEFICIT/HYPERACTIVITY DISORDER COMBINED TYPE, BUT NOT TO THE SAME EXTENT IN ONE OF THE ATTENTION-DEFICIT/HYPERACTIVITY DISORDER INATTENTIVE TYPE"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.volume","33"],["dc.contributor.author","Becker, A."],["dc.contributor.author","Lentzen, M."],["dc.contributor.author","Soonpaa, M."],["dc.contributor.author","Guan, Kaomei"],["dc.contributor.author","Field, Loren J."],["dc.date.accessioned","2018-11-07T09:07:28Z"],["dc.date.available","2018-11-07T09:07:28Z"],["dc.date.issued","2012"],["dc.format.extent","427"],["dc.identifier.isi","000308012403327"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25804"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.publisher.place","Oxford"],["dc.relation.conference","Congress of the European-Society-of-Cardiology (ESC)"],["dc.relation.eventlocation","Munchen, GERMANY"],["dc.relation.issn","0195-668X"],["dc.title","In-vivo coupling of long-term engrafted mESC-derived cardiomyocytes"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","69"],["dc.bibliographiccitation.lastpage","99"],["dc.contributor.author","Roessner, Veit"],["dc.contributor.author","Becker, A."],["dc.contributor.author","Banaschewski, Tobias"],["dc.contributor.author","Rothenberger, A."],["dc.contributor.editor","Fleischhacker, W. W."],["dc.date.accessioned","2018-11-07T08:42:24Z"],["dc.date.available","2018-11-07T08:42:24Z"],["dc.date.issued","2005"],["dc.description.abstract","Over the last years evidence on the overlap between tic-disorders (TD) and obsessive compulsive behavior/disorder (OCB/OCD) has increased. The main focus of research have been the phenomenological and epidemiological similarities and differences in samples of different age, primary diagnosis (TD vs. OCD) including the co-occurrence of both. Unfortunately, only a minority of studies included all three groups (TD, TD + OCD, OCD). Nevertheless, new insight concerning possible subtypes for both TD and OCD has been gained. While some authors concentrated on OCD with/without tics we will summarize the field of TD and OCB/OCD from the viewpoint of tics, since OCB plays an important role in patients with TD. Thereby we will not only sharpen the clinicans' awareness of known differences in phenomenology, epidemiology, genetics and neurobiology, aimed to improve their diagnoses and treatment but also highlight the gaps of knowledge and discuss possibilities for further research in this field."],["dc.identifier.isi","000233962600006"],["dc.identifier.pmid","16355604"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19691"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Wien"],["dc.relation.isbn","3-211-26292-X"],["dc.relation.isbn","978-3-211-26292-4"],["dc.relation.ispartof","Neurodevelopmental disorders"],["dc.relation.issn","0303-6995"],["dc.title","Tic disorders and obsessive compulsive disorder: where is the link?"],["dc.type","book_chapter"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","328"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Journal of Medical Primatology"],["dc.bibliographiccitation.lastpage","334"],["dc.bibliographiccitation.volume","38"],["dc.contributor.author","Mätz-Rensing, K."],["dc.contributor.author","Winkelmann, J."],["dc.contributor.author","Becker, T."],["dc.contributor.author","Burckhardt, I."],["dc.contributor.author","van der Linden, M."],["dc.contributor.author","Köndgen, S."],["dc.contributor.author","Leendertz, F."],["dc.contributor.author","Kaup, F.-J."],["dc.date.accessioned","2022-10-06T13:25:18Z"],["dc.date.available","2022-10-06T13:25:18Z"],["dc.date.issued","2009"],["dc.identifier.doi","10.1111/j.1600-0684.2009.00359.x"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114806"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1600-0684"],["dc.relation.issn","0047-2565"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Outbreak of\n Streptococcus equi\n subsp.\n zooepidemicus\n infection in a group of rhesus monkeys (\n Macaca mulatta\n )"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1171"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Global Change Biology"],["dc.bibliographiccitation.lastpage","1184"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Veldkamp, Edzo"],["dc.contributor.author","Becker, Anja"],["dc.contributor.author","Schwendenmann, Luitgard"],["dc.contributor.author","Clark, Deborah A."],["dc.contributor.author","Schulte-Bisping, Hubert"],["dc.date.accessioned","2017-09-07T11:54:55Z"],["dc.date.available","2017-09-07T11:54:55Z"],["dc.date.issued","2003"],["dc.description.abstract","Contrary to large areas in Amazonia of tropical moist forests with a pronounced dry season, tropical wet forests in Costa Rica do not depend on deep roots to maintain an evergreen forest canopy through the year. At our Costa Rican tropical wet forest sites, we found a large carbon stock in the subsoil of deeply weathered Oxisols, even though only 0.04–0.2% of the measured root biomass (>2 mm diameter) to 3 m depth was below 2 m. In addition, we demonstrate that 20% or more of this deep soil carbon (depending on soil type) can be mobilized after forest clearing for pasture establishment. Microbial activity between 0.3 and 3 m depth contributed about 50% to the microbial activity in these soils, confirming the importance of the subsoil in C cycling. Depending on soil type, forest clearing for pasture establishment led from no change to a slight addition of carbon in the topsoil (0–0.3 m depth). However, this effect was countered by a substantial loss of C stocks in the subsoil (1–3 m depth). Our results show that large stocks of relatively labile carbon are not limited to areas with a prolonged dry season, but can also be found in deeply weathered soils below tropical wet forests. Forest clearing in such areas may produce unexpectedly high C losses from the subsoil."],["dc.identifier.doi","10.1046/j.1365-2486.2003.00656.x"],["dc.identifier.gro","3150152"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/6884"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.issn","1354-1013"],["dc.subject","Costa Rica; deforestation; land-use change; microbial activity; pasture; soil organic carbon; tropical rain forest"],["dc.title","Substantial labile carbon stocks and microbial activity in deeply weathered soils below a tropical wet forest"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Geburtshilfe und Frauenheilkunde"],["dc.bibliographiccitation.volume","82"],["dc.contributor.author","Jaeger, A"],["dc.contributor.author","Hampl, M"],["dc.contributor.author","Zu Eulenburg, C"],["dc.contributor.author","Prieske, K"],["dc.contributor.author","Hambrecht, J"],["dc.contributor.author","Fuerst, S"],["dc.contributor.author","Klapdor, R"],["dc.contributor.author","Heublein, S"],["dc.contributor.author","Gass, P"],["dc.contributor.author","Rohner, A"],["dc.contributor.author","Canzler, U"],["dc.contributor.author","Becker, S"],["dc.contributor.author","Bommert, M"],["dc.contributor.author","Bauerschlag, D"],["dc.contributor.author","Denecke, A"],["dc.contributor.author","Hanker, L"],["dc.contributor.author","Runnebaum, I"],["dc.contributor.author","Forner, DM"],["dc.contributor.author","Schochter, F"],["dc.contributor.author","Klar, M"],["dc.contributor.author","Schwab, R"],["dc.contributor.author","Koepke, M"],["dc.contributor.author","Kalder, M"],["dc.contributor.author","Hantschmann, P"],["dc.contributor.author","Ratiu, D"],["dc.contributor.author","Denschlag, D"],["dc.contributor.author","Schroeder, W"],["dc.contributor.author","Tuschy, B"],["dc.contributor.author","Baumann, K"],["dc.contributor.author","Mustea, A"],["dc.contributor.author","Soergel, P"],["dc.contributor.author","Bronger, H"],["dc.contributor.author","Bauerschmitz, G"],["dc.contributor.author","Kosse, J"],["dc.contributor.author","Koch, MC"],["dc.contributor.author","Ignatov, A"],["dc.contributor.author","Sehouli, J"],["dc.contributor.author","Dannecker, C"],["dc.contributor.author","Mahner, S"],["dc.contributor.author","Woelber, L"],["dc.date.accessioned","2022-11-01T10:16:51Z"],["dc.date.available","2022-11-01T10:16:51Z"],["dc.date.issued","2022"],["dc.identifier.doi","10.1055/s-0042-1756881"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/116671"],["dc.notes.intern","DOI-Import GROB-605"],["dc.publisher","Georg Thieme Verlag"],["dc.relation.conference","64. Kongress der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe e. V."],["dc.relation.eventend","2022-10-15"],["dc.relation.eventlocation","München"],["dc.relation.eventstart","2022-10-12"],["dc.title","Risiko für eine pelvine Metastasierung und Stellenwert der pelvinen Lymphonodektomie bei Patientinnen mit nodal-positivem Vulvakarzinom – Ergebnisse der AGO-VOP.2/QS Vulva Studie"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","15765"],["dc.bibliographiccitation.issue","40"],["dc.bibliographiccitation.journal","PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA"],["dc.bibliographiccitation.lastpage","15770"],["dc.bibliographiccitation.volume","104"],["dc.contributor.author","Beckers, Anja"],["dc.contributor.author","Alten, Leonie"],["dc.contributor.author","Viebahn, Christoph"],["dc.contributor.author","Andre, Philipp"],["dc.contributor.author","Gossler, Achim"],["dc.date.accessioned","2018-11-07T10:57:51Z"],["dc.date.available","2018-11-07T10:57:51Z"],["dc.date.issued","2007"],["dc.description.abstract","The mouse homeobox gene Noto represents the homologue of zebrafish floating head (flh) and is expressed in the organizer node and in the nascent notochord. Previous analyses suggested that Noto is required exclusively for the formation of the caudal part of the notochord. Here, we show that Noto is also essential for node morphogenesis, controlling ciliogenesis in the posterior notochord, and the establishment of laterality, whereas organizer functions in anterior-posterior patterning are apparently not compromised. In mutant embryos, left-right asymmetry of internal organs and expression of laterality markers was randomized. Mutant posterior notochord regions were variable in size and shape, cilia were shortened with highly irregular axonemal microtubuli, and basal bodies were, in part, located abnormally deep in the cytoplasm. The transcription factor Foxj1, which regulates the dynein gene Dnahc11 and is required for the correct anchoring of basal bodies in lung epithelial cells, was down-regulated in mutant nodes. Likewise, the transcription factor Rfx3, which regulates cilia growth, was not expressed in Noto mutants, and various other genes important for cilia function or assembly such as Dnahc5 and Nphp3 were down-regulated. Our results establish Noto as an essential regulator of node morphogenesis and ciliogenesis in the posterior notochord, and suggest Noto acts upstream of Foxj1 and Rfx3."],["dc.identifier.doi","10.1073/pnas.0704344104"],["dc.identifier.isi","000249942700032"],["dc.identifier.pmid","17884984"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50346"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Natl Acad Sciences"],["dc.relation.issn","0027-8424"],["dc.title","The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left-right patterning"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","811"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Theriogenology"],["dc.bibliographiccitation.lastpage","816"],["dc.bibliographiccitation.volume","78"],["dc.contributor.author","Hanazawa, K."],["dc.contributor.author","Mueller, T."],["dc.contributor.author","Becker, T."],["dc.contributor.author","Heistermann, M."],["dc.contributor.author","Behr, R."],["dc.contributor.author","Sasaki, E."],["dc.date.accessioned","2022-10-06T13:33:24Z"],["dc.date.available","2022-10-06T13:33:24Z"],["dc.date.issued","2012"],["dc.identifier.doi","10.1016/j.theriogenology.2012.03.029"],["dc.identifier.pii","S0093691X12002002"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115624"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.issn","0093-691X"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Minimally invasive transabdominal collection of preimplantation embryos from the common marmoset monkey (Callithrix jacchus)"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","327"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Veterinary Pathology"],["dc.bibliographiccitation.lastpage","334"],["dc.bibliographiccitation.volume","44"],["dc.contributor.author","Mätz-Rensing, K."],["dc.contributor.author","Floto, A."],["dc.contributor.author","Schrod, A."],["dc.contributor.author","Becker, T."],["dc.contributor.author","Finke, E. J."],["dc.contributor.author","Seibold, E."],["dc.contributor.author","Splettstoesser, W. D."],["dc.contributor.author","Kaup, F.-J."],["dc.date.accessioned","2022-10-06T13:26:19Z"],["dc.date.available","2022-10-06T13:26:19Z"],["dc.date.issued","2016"],["dc.description.abstract","Tularemia is a highly contagious infectious zoonosis, transmissible by inoculation, ingestion, or inhalation of the infectious agent Francisella tularensis. The disease is perpetuated by infected rodents, blood-sucking arthropods, and by contaminated water. Therefore, nonhuman primates housed outdoors may be at risk for exposure. An epizootic of F. tularensis occurred in an indoor/outdoor-housed group of cynomolgus monkeys ( Macaca fascicularis) at the German Primate Center. Tularemia was diagnosed in 18 out of 35 animals within a period of 2 years. Six animals died with unspecific clinical symptoms; 12 animals developed seroconversion and were still alive. Pathologic findings were similar in all monkeys that died and resembled the clinical picture of the human disease, including an ulceroglandular syndrome with local lymphadenopathy, gingivostomatitis, and systemic spread, with manifestations such as subacute necrotizing hepatitis, granulomatous splenitis, and pneumonia. Tularemia was diagnosed by culture, real-time polymerase chain reaction, and ELISA techniques. This is the largest outbreak in nonhuman primates and the first report of tularemia in cynomolgus monkeys. An overview of the recent literature about tularemia in nonhuman primates is given."],["dc.identifier.doi","10.1354/vp.44-3-327"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/115059"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-602"],["dc.relation.eissn","1544-2217"],["dc.relation.issn","0300-9858"],["dc.relation.orgunit","Deutsches Primatenzentrum"],["dc.title","Epizootic of Tularemia in an Outdoor Housed Group of Cynomolgus Monkeys (\n Macaca fascicularis\n )"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]