Janssen, Iryna

[["dc.bibliographiccitation.firstpage","916"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Emerging Infectious Diseases"],["dc.bibliographiccitation.lastpage","919"],["dc.bibliographiccitation.volume","24"],["dc.contributor.author","Janssen, Hauke"],["dc.contributor.author","Janssen, Iryna"],["dc.contributor.author","Cooper, Paul"],["dc.contributor.author","Kainyah, Clemens"],["dc.contributor.author","Pellio, Theresia"],["dc.contributor.author","Quintel, Michael"],["dc.contributor.author","Monnheimer, Mathieu"],["dc.contributor.author","Groß, Uwe"],["dc.contributor.author","Schulze, Marco H."],["dc.date.accessioned","2020-12-10T18:44:07Z"],["dc.date.available","2020-12-10T18:44:07Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.3201/eid2405.171506"],["dc.identifier.eissn","1080-6059"],["dc.identifier.issn","1080-6040"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78338"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Antimicrobial-Resistant Bacteria in Infected Wounds, Ghana, 20141"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","4487"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","International Journal of Systematic and Evolutionary Microbiology"],["dc.bibliographiccitation.lastpage","4493"],["dc.bibliographiccitation.volume","67"],["dc.contributor.author","Huber, Katharina"],["dc.contributor.author","Geppert, Alicia M."],["dc.contributor.author","Groß, Uwe"],["dc.contributor.author","Luckner, Manja"],["dc.contributor.author","Wanner, Gerhard"],["dc.contributor.author","Cooper, Paul"],["dc.contributor.author","Abakah, John"],["dc.contributor.author","Janssen, Iryna"],["dc.contributor.author","Overmann, Jörg"],["dc.date.accessioned","2018-10-09T07:44:34Z"],["dc.date.available","2018-10-09T07:44:34Z"],["dc.date.issued","2017-11"],["dc.description.abstract","Members of the class Blastocatellia are frequently found in soils with a neutral and (slightly) basic pH where they constitute an important fraction of the microbial community. A novel representative of the class Blastocatellia was isolated from a Ghanaian soil and was characterized in detail. Cells of strain A24_SHP_-5_238T were non-motile rods that divided by binary fission and formed orange to salmon-coloured colonies on agar plates. Strain A24_SHP_-5_238T tolerated pH values of pH 6.0-9.0 (best growth at pH 7.0-8.5) and temperature values of 8-45 °C (best growth at 33-40 °C). It grew chemo-organoheterotrophically on several sugars, a few amino acids, organic acids and different complex protein substrates. In addition, strain A24_SHP_-5_238T was able to use nitrate as an alternative electron acceptor in the absence of oxygen. Major fatty acids of A24_SHP_-5_238T were iso-C15 : 0, summed feature 1 (C13 : 0 3-OH/iso-C15 : 1 H), summed feature 3 (C16 : 1ω7c/C16 : 1ω6c), anteiso-C17 : 0 and anteiso-C15 : 0. The major quinone was MK-8, and the DNA G+C content was 53.5 mol%. The closest described phylogenetic relatives were Aridibacter famidurans A22_HD_4HT and Aridibacter kavangonensis Ac_23_E3T with a 16S rRNA gene sequence identity of 97.6 and 97.2 %, respectively. The DNA-DNA hybridization values (<28.5 %) confirmed that A24_SHP_-5_238T represents a novel species within the genus Aridibacter. Based on its morphological, physiological and molecular characteristics, we propose the novel species Aridibacter nitratireducens sp. nov. (type strain A24_SHP_-5_238T = DSM 102177T = CECT 9235T)."],["dc.fs.pkfprnr","65352"],["dc.identifier.doi","10.1099/ijsem.0.002318"],["dc.identifier.fs","632159"],["dc.identifier.pmid","28945537"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/15898"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.relation.eissn","1466-5034"],["dc.title","Aridibacter nitratireducens sp. nov., a member of the family Blastocatellaceae, class Blastocatellia, isolated from an African soil"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","1843"],["dc.bibliographiccitation.journal","Frontiers in Microbiology"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Seugendo, Mwanaisha"],["dc.contributor.author","Janssen, Iryna"],["dc.contributor.author","Lang, Vanessa"],["dc.contributor.author","Hasibuan, Irene"],["dc.contributor.author","Bohne, Wolfgang"],["dc.contributor.author","Cooper, Paul"],["dc.contributor.author","Daniel, Rolf"],["dc.contributor.author","Gunka, Katrin"],["dc.contributor.author","Kusumawati, R. L."],["dc.contributor.author","Mshana, Stephen E."],["dc.contributor.author","von Müller, Lutz"],["dc.contributor.author","Okamo, Benard"],["dc.contributor.author","Ortlepp, Jan R."],["dc.contributor.author","Overmann, Jörg"],["dc.contributor.author","Riedel, Thomas"],["dc.contributor.author","Rupnik, Maja"],["dc.contributor.author","Zimmermann, Ortrud"],["dc.contributor.author","Groß, Uwe"],["dc.date.accessioned","2019-07-09T11:45:47Z"],["dc.date.available","2019-07-09T11:45:47Z"],["dc.date.issued","2018"],["dc.description.abstract","Clostridioides (Clostridium) difficile infections (CDI) are considered worldwide as emerging health threat. Uptake of C. difficile spores may result in asymptomatic carrier status or lead to CDI that could range from mild diarrhea, eventually developing into pseudomembranous colitis up to a toxic megacolon that often results in high mortality. Most epidemiological studies to date have been performed in middle- and high income countries. Beside others, the use of antibiotics and the composition of the microbiome have been identified as major risk factors for the development of CDI. We therefore postulate that prevalence rates of CDI and the distribution of C. difficile strains differ between geographical regions depending on the regional use of antibiotics and food habits. A total of 593 healthy control individuals and 608 patients suffering from diarrhea in communities in Germany, Ghana, Tanzania and Indonesia were selected for a comparative multi-center cross-sectional study. The study populations were screened for the presence of C. difficile in stool samples. Cultured C. difficile strains (n = 84) were further subtyped and characterized using PCR-ribotyping, determination of toxin production, and antibiotic susceptibility testing. Prevalence rates of C. difficile varied widely between the countries. Whereas high prevalence rates were observed in symptomatic patients living in Germany and Indonesia (24.0 and 14.7%), patients from Ghana and Tanzania showed low detection rates (4.5 and 6.4%). Differences were also obvious for ribotype distribution and toxin repertoires. Toxin A+/B+ ribotypes 001/072 and 078 predominated in Germany, whereas most strains isolated from Indonesian patients belonged to toxin A+/B+ ribotype SLO160 and toxin A-/B+ ribotype 017. With 42.9-73.3%, non-toxigenic strains were most abundant in Africa, but were also found in Indonesia at a rate of 18.2%. All isolates were susceptible to vancomycin and metronidazole. Mirroring the antibiotic use, however, moxifloxacin resistance was absent in African C. difficile isolates but present in Indonesian (24.2%) and German ones (65.5%). This study showed that CDI is a global health threat with geographically different prevalence rates which might reflect distinct use of antibiotics. Significant differences for distributions of ribotypes, toxin production, and antibiotic susceptibilities were observed."],["dc.identifier.doi","10.3389/fmicb.2018.01843"],["dc.identifier.pmid","30131799"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15318"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59311"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1664-302X"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","610"],["dc.title","Prevalence and Strain Characterization of Clostridioides (Clostridium) difficile in Representative Regions of Germany, Ghana, Tanzania and Indonesia - A Comparative Multi-Center Cross-Sectional Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","652"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","International Journal of Medical Microbiology"],["dc.bibliographiccitation.lastpage","656"],["dc.bibliographiccitation.volume","306"],["dc.contributor.author","Janssen, Iryna"],["dc.contributor.author","Cooper, Paul"],["dc.contributor.author","Gunka, Katrin"],["dc.contributor.author","Rupnik, Maja"],["dc.contributor.author","Wetzel, Daniela"],["dc.contributor.author","Zimmermann, Ortrud"],["dc.contributor.author","Gross, Uwe"],["dc.date.accessioned","2018-11-07T10:05:02Z"],["dc.date.available","2018-11-07T10:05:02Z"],["dc.date.issued","2016"],["dc.description.abstract","Since data about Clostridium difficile infection in sub-Saharan Africa are scarce, we determined its epidemiology and risk factors in a cross-sectional study in Eikwe, a rural community in Ghana. We tested stool samples from 176 hospitalized patients with diarrhoea and from 131 asymptomatic non-hospitalized individuals for C difficile and some other enteric pathogens. The overall prevalence rate of C difficile was 4.9% with ribotype 084 being predominant. With 75% of the isolates, a high rate of nontoxigenic strains was present in symptomatic patients, most of whom had no other identified enteric pathogens. All strains were susceptible against metronidazole and vancomycin, respectively. Data on lifestyle and medical history showed that age <5 years (p=0.004), and use of ceftriaxone (p =0.023) were the most important risk factors for C difficile carriage status. Although our data suggest that C. difficile is currently not a major cause of diarrhoea in this setting, the epidemiology of C difficile in sub-Saharan Africa awaits further investigation. (C) 2016 Elsevier GmbH. All rights reserved."],["dc.description.sponsorship","Federal State of Lower Saxony, Niedersachsisches Vorab [VWZN2889]"],["dc.identifier.doi","10.1016/j.ijmm.2016.09.004"],["dc.identifier.isi","000390824600007"],["dc.identifier.pmid","27693000"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38815"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Gmbh, Urban & Fischer Verlag"],["dc.relation.issn","1618-0607"],["dc.relation.issn","1438-4221"],["dc.title","High prevalence of nontoxigenic Clostridium difficile isolated from hospitalized and non-hospitalized individuals in rural Ghana"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]