Lindena-Gläß, Gabriele

[["dc.bibliographiccitation.firstpage","1157"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Supportive Care in Cancer"],["dc.bibliographiccitation.lastpage","1163"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Ostgathe, Christoph"],["dc.contributor.author","Gaertner, Jan"],["dc.contributor.author","Kotterba, Maren"],["dc.contributor.author","Klein, Sebastian"],["dc.contributor.author","Lindena, Gabriele"],["dc.contributor.author","Nauck, Friedemann"],["dc.contributor.author","Radbruch, Lukas"],["dc.contributor.author","Voltz, Raymond"],["dc.date.accessioned","2018-11-07T08:40:13Z"],["dc.date.available","2018-11-07T08:40:13Z"],["dc.date.issued","2010"],["dc.description.abstract","Cancer may affect the central nervous system either by primary or secondary brain tumours (PBT/SBT). Specific needs of these patients and special requirements of services caring for them have not been adequately addressed so far. Since 1999, an annual, 3-month census is being conducted in different palliative care settings throughout Germany. Pooled data from the years 2002-2005 were analysed to test for differences between patients with PBT, SBT and other palliative care patients (OP). Symptom frequencies, ECOG status and nursing needs were tested for differences (chi A(2)). Free text entries for reasons for admission were recorded, categorised and analysed descriptively. A total of 5,684 patients were documented (PBT n = 153, 2.7%; SBT n = 661, 11.9%; OP n = 4,872, 85.4%). For patients with PBT, poor functional status and high need for nursing support was reported more frequently than for patients with SBT and OP. For patients with PBT/SBT physical symptoms (pain, nausea, vomiting, constipation and loss of appetite) were documented less frequently and in lower intensity than for OP. However, nursing, psychological, and social problems/symptoms were documented significantly more often and showed higher intensity, particularly the patients' need for support with the activities of daily living, disorientation/confusion of the patients and overburdening of the family. For 67% of all patients, a reason for admission was documented in free text. Main reasons were symptom control (OP > SBT > PBT), social issues (PBT > SBT > OP), functional deficits (PBT > SBT > OP) and cognitive impairment (PBT/SBT > OP). Distinct neurological deficits and problems were documented more often as secondary ICD-diagnoses than as a leading reason for admission. The specific palliative care problems and the rationales leading to health care utilisation point to the need for an appropriate interdisciplinary and multi-professional provision of care for patients with brain malignancies, with a particular view on the needs of the families and an early integration of social and psychological support."],["dc.identifier.doi","10.1007/s00520-009-0735-y"],["dc.identifier.isi","000280405800006"],["dc.identifier.pmid","19763633"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/6760"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/19174"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0941-4355"],["dc.relation.orgunit","Klinik für Palliativmedizin"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Differential palliative care issues in patients with primary and secondary brain tumours"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","325"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Supportive Care in Cancer"],["dc.bibliographiccitation.lastpage","333"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Stiel, Stephanie"],["dc.contributor.author","Krumm, Norbert"],["dc.contributor.author","Pestinger, Martina"],["dc.contributor.author","Lindena, Gabriele"],["dc.contributor.author","Nauck, Friedemann"],["dc.contributor.author","Ostgathe, Christoph"],["dc.contributor.author","Radbruch, Lukas"],["dc.contributor.author","Elsner, Frank"],["dc.date.accessioned","2018-11-07T09:14:10Z"],["dc.date.available","2018-11-07T09:14:10Z"],["dc.date.issued","2012"],["dc.description.abstract","Patients with advanced cancer are highly susceptible to infections. The decision whether to treat an active or suspected infection or to withhold or withdraw an antibiotic treatment in end-of-life care may be difficult. In order to quantify the antimicrobial prescribing practices and decision-making processes in palliative care units in Germany, a survey was performed as part of the Hospice and Palliative Evaluation in 2006. With a specifically designed questionnaire, 448 patients for whom an active or suspected infection and antibiotic treatment was discussed were documented. Data on the use of and indication for antibiotic treatment and the decision-making on withdrawal or withholding of antibiotic therapy were collected. 286 (63.8%) received an antibiotic therapy. In 88 cases, withdrawal of an ongoing treatment was documented. The most frequent reasons for withdrawal were: deterioration of general status (41.4%), inefficiency of therapy (25.7%), and explicit wish of patient (14.3%; multiple answers possible). Outcome of antimicrobial therapy was rated poor or very poor for a fifth of the cases and accordingly, antibiotics were more likely to be withdrawn if the clinical success was considered to be poor. The initiation of therapy was often decided by physicians solely, whereas withdrawing and withholding therapy demanded more often involvement of other team members in the decision-making process. The initiation of therapy seems to be easier than withdrawing and withholding, as involvement of other team members in the decision-making process was then sought more often. When antibiotics were given until death, the indication should be reconsidered because of a possibly undesirable prolongation of the dying process. Clinical practice may benefit from clear definitions of treatment goals and outcome criteria to better evaluate the necessity for and success of antimicrobial treatment."],["dc.identifier.doi","10.1007/s00520-011-1084-1"],["dc.identifier.isi","000298356500014"],["dc.identifier.pmid","21274577"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27343"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0941-4355"],["dc.relation.orgunit","Klinik für Palliativmedizin"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Antibiotics in palliative medicine-results from a prospective epidemiological investigation from the HOPE survey"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","94"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Onkologie"],["dc.bibliographiccitation.lastpage","98"],["dc.bibliographiccitation.volume","34"],["dc.contributor.author","Neuwöhner, Karl"],["dc.contributor.author","Lindena, Gabriele"],["dc.date.accessioned","2019-07-09T11:53:48Z"],["dc.date.available","2019-07-09T11:53:48Z"],["dc.date.issued","2011"],["dc.description.abstract","BACKGROUND: Within the framework of the nationwide Hospice and Palliative Care Evaluation (HOPE), the German Basic Documentation for Psycho-oncology (PO-Bado) was used from 2004 to 2006 as an optional module in most participating palliative care services to investigate how patient distress due to symptom burdens in different palliative care settings should be assessed and how professional interventions could be derived. PATIENTS AND METHODS: The distress scores of 3,317 PO-Bado records out of a total of 6,958 consecutive participants from 3 yearly samples of HOPE were evaluated descriptively and compared with a reference sample of cancer patients from both general and university hospitals. RESULTS: The relative values of distress from physical and psychological symptoms were 0.57 and 0.37 (maximum of 1.0), respectively. In 38.2% of the patients, professional psychosocial interventions were indicated. Compared to the reference sample of cancer patients, palliative care patients clearly showed more specific physical distress, but psychological symptoms were varied; in particular, distress from cognitive impairment, helplessness and grief showed higher intensities in palliative care patients than in the reference group. CONCLUSIONS: The PO-Bado rating scales assessed high levels of distress, particularly from physical symptoms, in palliative care patients. A large percentage of palliative care patients required professional psychosocial support."],["dc.description.abstract","Hintergrund: Im Rahmen der bundesweiten Hospiz- und Palliativerhebung HOPE wurde von 2004 bis 2006 die Psychoonkologische Basisdokumentation (PO-Bado) in den meisten teilnehmenden Institutionen als optionale Ergänzung eingesetzt, um festzustellen, wie die psychische Belastung der Patienten in Hospiz- und Palliativeinrichtungen eingeschätzt und wie daraus die Indikation für eine professionelle Intervention abgeleitet werden kann. Patienten und Methoden: Die Belastungsangaben in 3317 PO-Bado-Datensätzen von insgesamt 6958 Teilnehmern aus 3 jährlichen Stichproben der bundesweiten HOPE-Dokumentation wurden deskriptiv ausgewertet und mit Daten einer Referenzgruppe aus allgemein onkologischen Einrichtungen verglichen. Ergebnisse: Der relative Summenwert der Belastung durch somatische Symptome lag bei 0,57 (maximal 1), durch psychische Symptome bei 0,37. Eine Indikation für eine professionelle psychosoziale Unterstützung wurde bei 38,2% der Patienten gesehen. Im Vergleich zu einer Referenzstichprobe von onkologischen Patienten zeigen Palliativpatienten deutlich stärkere körperliche Belastungen, während die psychischen Belastungen sich differenzieren: höher als in der Referenzgruppe waren die Belastungen durch kognitive Einschränkungen, Hilflosigkeit/Ausgeliefertsein und Trauer/Niedergeschlagenheit. Schlussfolgerungen: Die hohe psychische Belastung durch vor allem somatische Symptome wird bei Palliativpatienten in Deutschland mit Hilfe des PO-Bado-Moduls erfasst. Eine psychosoziale Unterstützung wird in vielen Fällen als notwendig angesehen."],["dc.identifier.doi","10.1159/000324784"],["dc.identifier.fs","577676"],["dc.identifier.pmid","21358213"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8059"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/60501"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.issn","1423-0240"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.mesh","Aged"],["dc.subject.mesh","Comorbidity"],["dc.subject.mesh","Female"],["dc.subject.mesh","Germany"],["dc.subject.mesh","Hospice Care"],["dc.subject.mesh","Humans"],["dc.subject.mesh","Male"],["dc.subject.mesh","Neoplasms"],["dc.subject.mesh","Palliative Care"],["dc.subject.mesh","Personality Assessment"],["dc.subject.mesh","Psychometrics"],["dc.subject.mesh","Reproducibility of Results"],["dc.subject.mesh","Risk Assessment"],["dc.subject.mesh","Risk Factors"],["dc.subject.mesh","Sensitivity and Specificity"],["dc.subject.mesh","Stress, Psychological"],["dc.title","Assessment of distress with physical and psychological symptoms of patients in german palliative care services."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","148"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Palliative Medicine"],["dc.bibliographiccitation.lastpage","152"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Ostgathe, Christoph"],["dc.contributor.author","Alt-Epping, Bernd"],["dc.contributor.author","Golla, Heidrun"],["dc.contributor.author","Gaertner, Jan"],["dc.contributor.author","Lindena, Gabriele"],["dc.contributor.author","Radbruch, Lukas"],["dc.contributor.author","Voltz, Raymond"],["dc.date.accessioned","2018-11-07T08:59:06Z"],["dc.date.available","2018-11-07T08:59:06Z"],["dc.date.issued","2011"],["dc.description.abstract","To determine the role of non-cancer palliative care in inpatient services in Germany, data from the Hospice and Palliative Care Evaluation (HOPE) were analysed. Since 1999, a three-month census has been conducted annually in German palliative care units. Pooled data from 2002-2005 were tested for differences between non-cancer patients (NCs) and cancer patients (Cs). A total of 4182 patients (NC: 3.5%; C: 96.5%) were documented; functional status (using Eastern Cooperative Oncology Group (ECOG) measures) in NCs was lower compared to Cs (p = 0.009). NCs suffered more often from dyspnoea (40%; C: 29%; p = 0.004), weakness (92,3%; C: 84,5%; p = 0.011) and tiredness (75.4%; C: 66.7%; p = 0.03) and less from nausea (17.1%; C: 28.9%; p = 0.002), vomiting (8.2%; C: 19.4%; p = 0.001) or loss of appetite (55.5%; C: 67.9%; p = 0.002). There were no differences in pain and constipation. Other problems (nursing, psychological) were more frequent for NCs, in particular the need for support in the activities of daily life (90.3%; C: 72.8%; p < 0.001) and disorientation/confusion (32.1%; C: 17.2%; p < 0.001). There were no differences in social problems. NCs are still rare in specialized inpatient palliative care institutions in Germany. The palliative care needs in patients with nonmalignant disease will challenge the health care system as the workload for these services will grow over proportionally."],["dc.description.sponsorship","Mundipharma Company, Limburg; German Cancer Aid"],["dc.identifier.doi","10.1177/0269216310385370"],["dc.identifier.isi","000288367500006"],["dc.identifier.pmid","20937612"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8168"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23808"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Sage Publications Ltd"],["dc.relation.issn","0269-2163"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Non-cancer patients in specialized palliative care in Germany: What are the problems?"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","5"],["dc.bibliographiccitation.journal","BMC Musculoskeletal Disorders"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Schmidt, Carsten Oliver"],["dc.contributor.author","Chenot, Jean-Francois"],["dc.contributor.author","Pfingsten, Michael"],["dc.contributor.author","Fahland, Ruth Anja"],["dc.contributor.author","Lindena, Gabriele"],["dc.contributor.author","Marnitz, Ulf"],["dc.contributor.author","Pfeifer, Klaus"],["dc.contributor.author","Kohlmann, Thomas"],["dc.date.accessioned","2018-11-07T08:46:48Z"],["dc.date.available","2018-11-07T08:46:48Z"],["dc.date.issued","2010"],["dc.description.abstract","Background: Although most patients with low back pain (LBP) recover within a few weeks a significant proportion has recurrent episodes or will develop chronic low back pain. Several mainly psychosocial risk factors for developing chronic LBP have been identified. However, effects of preventive interventions aiming at behavioural risk factors and unfavourable cognitions have yielded inconsistent results. Risk tailored interventions may provide a cost efficient and effective means to take systematic account of the individual risk factors but evidence is lacking. Methods/Design: This study will be a cluster-randomised controlled trial comparing screening and a subsequent risk tailored intervention for patients with low back pain to prevent chronic low back pain compared to treatment as usual in primary care. A total of 600 patients from 20 practices in each study arm will be recruited in Berlin and Goettingen. The intervention comprises the following elements: Patients will be assigned to one of four risk groups based on a screening questionnaire. Subsequently they receive an educational intervention including information and counselling tailored to the risk group. A telephone/email consulting service for back pain related problems are offered independent of risk group assignment. The primary outcomes will be functional capacity and sick leave. Discussion: This trial will evaluate the effectiveness of screening for risk factors for chronic low back pain followed by a risk tailored intervention to prevent chronic low back pain. This trial will contribute new evidence regarding the flexible use of individual physical and psychosocial risk factors in general practice."],["dc.identifier.doi","10.1186/1471-2474-11-5"],["dc.identifier.isi","000274727900001"],["dc.identifier.pmid","20051119"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/5697"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20786"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1471-2474"],["dc.relation.orgunit","Institut für Allgemeinmedizin"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.title","Assessing a risk tailored intervention to prevent disabling low back pain - protocol of a cluster randomized controlled trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original_ja"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","2385"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","Supportive Care in Cancer"],["dc.bibliographiccitation.lastpage","2389"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Alt-Epping, Bernd"],["dc.contributor.author","Pache, S."],["dc.contributor.author","Lindena, Gabriele"],["dc.contributor.author","Nauck, F."],["dc.date.accessioned","2018-11-07T09:05:40Z"],["dc.date.available","2018-11-07T09:05:40Z"],["dc.date.issued","2012"],["dc.description.abstract","Anticancer therapies gain increasing attention and discussion in specialized palliative care institutions. Frequency, indication, attitude of team members, and modes of these therapies implemented in specialized palliative care settings are still under investigation. Descriptive analysis of the nationwide Hospice and Palliative Care Evaluation 2007 that collected data from palliative medicine, hospice care, and oncology institutions concerning the use of anticancer therapies. Three thousand one hundred eighty-four patients from 67 palliative care units, eight oncology wards, and other in- and outpatient institutions were registered. Two hundred eleven therapeutic interventions, mostly i.v. chemotherapy (28.9%), have been documented in all institutions except from inpatient hospices. Although all institutions were asked to keep records from \"palliative patients\", those patients treated in oncology services differed from patients on palliative care units with respect to prognosis, therapeutic intention (symptom control versus tumor remission), and team attitude. Anticancer therapies are incorporated into palliative care concepts. The described differences in palliative patients that are treated in specialized palliative care as compared to oncology services will have to be discussed with regard to selection of patients for specialized palliative care and the range of suitable treatment modalities in palliative care concepts."],["dc.identifier.doi","10.1007/s00520-011-1349-8"],["dc.identifier.isi","000308193500018"],["dc.identifier.pmid","22198166"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/8072"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25377"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0941-4355"],["dc.relation.orgunit","Klinik für Palliativmedizin"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Anticancer therapies in specialized palliative care-a multicenter survey"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]