Lüthje, Lars

[["dc.bibliographiccitation.firstpage","819"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Journal of the American College of Cardiology"],["dc.bibliographiccitation.lastpage","824"],["dc.bibliographiccitation.volume","59"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Stevenson, William G."],["dc.contributor.author","Luethje, Lars"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","John, Roy M."],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Michaud, Gregory F."],["dc.date.accessioned","2018-11-07T09:13:18Z"],["dc.date.available","2018-11-07T09:13:18Z"],["dc.date.issued","2012"],["dc.description.abstract","Objectives The purpose of this study was to evaluate the prevalence and mechanism of a misleading long post-pacing interval (PPI) upon entrainment of typical atrial flutter (AFL) from the cavotricuspid isthmus (CTI). Background In typical AFL, the PPI from entrainment at the CTI is expected to closely match the tachycardia cycle-length (TCL). Methods Sixty patients with confirmed CTI-dependent AFL were retrospectively analyzed and grouped into short (<= 30 ms) or long (>30 ms) PPI-TCL. Thereafter, we prospectively studied 16 patients to acquire the PPI-TCL at 4 CTI sites with entrainment at pacing cycle-lengths (PCLs) 10 to 40 ms shorter than the TCL. Conduction times during AFL and entrainment were compared in 5 segments of the AFL circuit. Results Eleven patients (18%) in the retrospective analysis had a long PPI-TCL after entrainment from the CTI. Subjects with long PPI-TCL had similar baseline characteristics but greater beat-to-beat TCL variability. In the prospective cohort, PPI-TCL was influenced by the difference between PCL and TCL and site of entrainment. Conduction delays associated with a long PPI-TCL were located predominantly in the segment activated first by the paced orthodromic wave front, and were mainly due to local pacing latency, as confirmed by the use of monophasic action potential catheters. Conclusions A long PPI upon entrainment of typical AFL from the CTI is common and due to delayed conduction with entrainment. Whether these findings apply to other macro-re-entrant tachycardias warrants further investigation. (J Am Coll Cardiol 2012; 59: 819-24) (C) 2012 by the American College of Cardiology Foundation"],["dc.identifier.doi","10.1016/j.jacc.2011.11.023"],["dc.identifier.isi","000300609300008"],["dc.identifier.pmid","22361402"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27142"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","0735-1097"],["dc.title","Misleading Long Post-Pacing Interval After Entrainment of Typical Atrial Flutter From the Cavotricuspid Isthmus"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","273"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","European Journal of Heart Failure"],["dc.bibliographiccitation.lastpage","280"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Luethje, Lars"],["dc.contributor.author","Renner, Bernd"],["dc.contributor.author","Kessels, Roger"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Raupach, Tobias"],["dc.contributor.author","Gerritse, Bart"],["dc.contributor.author","Tasci, Selcuk"],["dc.contributor.author","Schwab, Joerg O."],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Schott, Peter"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Unterberg-Buchwald, Christina"],["dc.contributor.author","Andreas, Stefan"],["dc.date.accessioned","2017-09-07T11:47:31Z"],["dc.date.available","2017-09-07T11:47:31Z"],["dc.date.issued","2009"],["dc.description.abstract","Aims The combined therapeutic impact of atrial overdrive pacing (ACIP) and cardiac resynchronization therapy (CRT) on central steep apnoea (CSA) in chronic heart failure (CHF) so far has not been investigated. We aimed to evaluate the effect of CRT alone and CRT + AOP on CSA in CHF patients and to compare the influence of CRT on CHF between CSA positive and CSA negative patients. Methods and results Thirty patients with CRT indication underwent full night polysomnography, echocardiography, exercise testing, and neurohumoral evaluation before and 3 months after CRT implantation. In CSA positive patients (60%), two additional steep studies were conducted after 3 months of CRT, with CRT alone or CRT + ACIP, in random order. Cardiac resynchronization therapy resulted in significant improvements of NYHA class, left ventricular ejection fraction, N-terminal pro-brain natriuretic peptide, VO(2)max, and quality of life irrespective of the presence of CSA. Cardiac resynchronization therapy also reduced the central apnoea-hypopnoea index (AHI) (33.6 +/- 14.3 vs. 23.8 +/- 16.9 h(-1); P < 0.01) and central apnoea index (17.3 +/- 14.1 vs. 10.9 +/- 13.9 h(-1); P < 0.01) without altering steep stages. Cardiac resynchronization therapy with atrial overdrive pacing resulted in a small but significant additional decrease of the central AHI (23.8 +/- 16.9 vs. 21.5 +/- 16.9 h(-1); P < 0.01). Conclusion In this study, CRT significantly improved CSA without altering sleep stages. Cardiac resynchronization therapy with atrial. overdrive pacing resulted in a significant but minor additional improvement of CSA. Positive effects of CRT were irrespective of the presence of CSA."],["dc.identifier.doi","10.1093/eurjhf/hfn042"],["dc.identifier.gro","3143143"],["dc.identifier.isi","000265845700008"],["dc.identifier.pmid","19147446"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/625"],["dc.notes.intern","WoS Import 2017-03-10 / Funder: Bakken Research Center, Maastricht, Netherlands"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1388-9842"],["dc.title","Cardiac resynchronization therapy and atrial overdrive pacing for the treatment of central sleep apnoea"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.volume","25"],["dc.contributor.author","Unterberg, Christina"],["dc.contributor.author","Luethje, Lars"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Buchwald, A."],["dc.date.accessioned","2018-11-07T10:46:39Z"],["dc.date.available","2018-11-07T10:46:39Z"],["dc.date.issued","2004"],["dc.format.extent","406"],["dc.identifier.isi","000224056501629"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/47793"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","W B Saunders Co Ltd"],["dc.publisher.place","London"],["dc.relation.conference","ESC Congress 2004"],["dc.relation.eventlocation","Munich, GERMANY"],["dc.relation.issn","0195-668X"],["dc.title","Restoration of blunted force-frequency-relationship by cardiac resynchronization in patients with severe chronic heart failure"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","927"],["dc.bibliographiccitation.issue","12"],["dc.bibliographiccitation.journal","Clinical Research in Cardiology"],["dc.bibliographiccitation.lastpage","929"],["dc.bibliographiccitation.volume","102"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Luthje, Lars"],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Vollmann, Dirk"],["dc.date.accessioned","2018-11-07T09:17:18Z"],["dc.date.available","2018-11-07T09:17:18Z"],["dc.date.issued","2013"],["dc.identifier.doi","10.1007/s00392-013-0612-z"],["dc.identifier.isi","000327208800009"],["dc.identifier.pmid","23989651"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/28132"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.publisher.place","Heidelberg"],["dc.relation.issn","1861-0692"],["dc.relation.issn","1861-0684"],["dc.title","Supraventricular tachycardia with 'A-A-V' response upon ventricular entrainment and transient 2:1 AV conduction block"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","997"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Heart Rhythm"],["dc.bibliographiccitation.lastpage","999"],["dc.bibliographiccitation.volume","2"],["dc.contributor.author","Luthje, L."],["dc.contributor.author","Drescher, T."],["dc.contributor.author","Zenker, Dieter"],["dc.contributor.author","Vollmann, Dirk"],["dc.date.accessioned","2018-11-07T10:56:11Z"],["dc.date.available","2018-11-07T10:56:11Z"],["dc.date.issued","2005"],["dc.description.abstract","Decompensated heart failure is the leading cause of hospital admissions for US Medicare patients.(1) Early detection of intrathoracic fluid accumulation may reduce the morbidity and mortality associated with cardiac decompensation, but appropriate tools for monitoring patients with chronic heart failure are lacking. Intrathoracic impedance measurement recently has been integrated in a triple-chamber implantable defibrillator (InSync Sentry (TM), Medtronic Inc., Minneapolis, MN, USA). The system can alert the patient with an audible signal if a decrease in intrathoracic impedance indicates pulmonary fluid accumulation due to cardiac decompensation. However, the clinical value of this monitoring function has not been evaluated. This is the first case report to describe detection of heart failure decompensation using intrathoracic impedance monitoring by an implantable device."],["dc.identifier.doi","10.1016/j.hrthm.2005.06.005"],["dc.identifier.isi","000231986200020"],["dc.identifier.pmid","16171758"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/49953"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Inc"],["dc.relation.issn","1547-5271"],["dc.title","Detection of heart failure decompensation using intrathoracic impedance monitoring by a triple-chamber implantable defibrillator"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1460"],["dc.bibliographiccitation.issue","10"],["dc.bibliographiccitation.journal","EP Europace"],["dc.bibliographiccitation.lastpage","1466"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Seegers, Joachim"],["dc.contributor.author","Zabel, Markus"],["dc.contributor.author","Luethje, Lars"],["dc.contributor.author","Vollmann, Dirk"],["dc.date.accessioned","2018-11-07T08:38:23Z"],["dc.date.available","2018-11-07T08:38:23Z"],["dc.date.issued","2010"],["dc.description.abstract","Ventricular oversensing remains a significant problem in modern implantable cardioverter-defibrillator (ICD) systems. The role of manufacturer-related differences in device-based signal processing on the one hand and sensing lead properties on the other is largely unknown. This retrospective study aimed to evaluate and compare the incidence and mechanisms of ventricular oversensing in single- or dual-chamber ICD systems from Biotronik (BTK), Guidant (GDT), and Medtronic (MDT). In 245 consecutive patients, device function, stored episodes, and lead parameters were evaluated at implant and during 243 +/- 18 days of follow-up. Oversensing occurred in 3.3% of the patients [four T-wave oversensing (TWO), three R-wave double-sensing, and one diaphragmatic myopotentials]. The incidence of ventricular oversensing was generally low if an ICD device and an ICD lead were from one identical manufacturer (BTK: 2/68, GDT: 1/80, and MDT: 1/69; P = 0.67). In the subgroup of ICDs connected to leads from other manufacturers, however, ventricular oversensing was observed in none of 19 GDT and MDT ICDs but in 4 of 9 BTK devices (44.4%, P = 0.012). These four cases of oversensing (three R-wave double-sensing and one TWO) all occurred in BTK ICDs connected to integrated bipolar ICD leads from other manufacturers. Significant manufacturer-related differences exist in the incidence of ventricular oversensing in single- and dual-chamber ICD systems. Biotronik devices connected to integrated bipolar ICD leads from other manufacturers have an increased risk for R-wave double-sensing."],["dc.description.sponsorship","Medtronic; Biotronik"],["dc.identifier.doi","10.1093/europace/euq269"],["dc.identifier.isi","000282429700012"],["dc.identifier.pmid","20663783"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/18757"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1099-5129"],["dc.title","Ventricular oversensing due to manufacturer-related differences in implantable cardioverter-defibrillator signal processing and sensing lead properties"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","275"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","EP Europace"],["dc.bibliographiccitation.lastpage","277"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Luethje, Lars"],["dc.contributor.author","Zabel, Markus"],["dc.date.accessioned","2018-11-07T11:02:39Z"],["dc.date.available","2018-11-07T11:02:39Z"],["dc.date.issued","2007"],["dc.description.abstract","We describe the case of a patient who presented with multiple implantable cardioverter-defibrillator (ICD) shock discharges 12 months after device implantation. Upon device interrogation, intermittent oversensing of electrical noise and potential ICD lead failure were suggested by a significant increase in the sensing integrity counter (SIC), a cumulative count of very short ventricular sensed intervals. Analysis of stored episodes, however, revealed that inappropriate ICD therapy had been caused by intermittent T-wave oversensing (TWO), and that the increase of the SIC resulted from the coincidence of TWO and premature ventricular complexes (PVCs). T-wave oversensing resolved and the SIC did not increase any more during follow-up after adjustment of ventricular sensitivity. The coincidence of TWO and PVCs should therefore be considered as an uncommon cause for short ventricular sensed intervals in ICD patients presenting with a suspect increase in the SIC."],["dc.identifier.doi","10.1093/europace/eum028"],["dc.identifier.isi","000247248900004"],["dc.identifier.pmid","17369268"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51431"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1099-5129"],["dc.title","Unusual cause for an increase of the sensing integrity counter in a patient with inappropriate implantable cardioverter-defibrittator therapy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","684"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","European Heart Journal - Cardiovascular Imaging"],["dc.bibliographiccitation.lastpage","691"],["dc.bibliographiccitation.volume","14"],["dc.contributor.author","Sohns, Christian"],["dc.contributor.author","Sohns, Jan Martin"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Luethje, Lars"],["dc.contributor.author","Bergau, Leonard"],["dc.contributor.author","Dorenkamp, Marc"],["dc.contributor.author","Zwaka, Paul A."],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Lotz, Joachim"],["dc.contributor.author","Zabel, Markus"],["dc.date.accessioned","2017-09-07T11:47:40Z"],["dc.date.available","2017-09-07T11:47:40Z"],["dc.date.issued","2013"],["dc.description.abstract","Aims This study aimed to identify whether left atrial (LA) volume assessed by multidetector computed tomography (MDCT) is related to the long-term success of pulmonary vein ablation (PVA). MDCT is used to guide PVA for the treatment of atrial fibrillation (AF). MDCT permits accurate sizing of LA dimensions. Methods and results We analysed data from 368 ablation procedures of 279 consecutive patients referred for PVA due to drug-refractory symptomatic AF (age 62 +/- 10; 58% men; 71% paroxysmal AF). Prior to the procedure, all patients underwent ECG-gated 64-MDCT scan for assessment of LA and PV anatomy, LA thrombus evaluation, LA volume estimation, and electroanatomical mapping integration. Within a mean follow-up of 356 +/- 128 days, 64% of the patients maintained sinus rhythm after the initial ablation, and 84% when including repeat PVA. LA diameter (P = 0.004), LA volume (P = 0.002), and type of AF (P = 0.001) were independent predictors of AF recurrence in univariate analysis. There was a relatively low correlation between the echocardiographic LA diameter and LA volume from MDCT (P = 0.01, r = 0.5). In multivariate analysis, paroxysmal AF (P < 0.006) and LA volume below the median value of 106 mL (P = 0.042) were significantly associated with the success of PVA, whereas LA diameter was not (P = 0.245). Analysing receiver-operator characteristics, the area under the curve for LA volume was 0.73 (P = 0.001) compared with 0.60 (P = 0.09) for LA diameter from echocardiography. Conclusion LA volume assessed by MDCT is a better predictor of AF recurrence after PVA than echocardiograpic LA diameter and can be derived from the pre-procedural imaging data set."],["dc.identifier.doi","10.1093/ehjci/jet017"],["dc.identifier.gro","3142334"],["dc.identifier.isi","000321462600013"],["dc.identifier.pmid","23435593"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/7131"],["dc.notes.intern","WoS Import 2017-03-10"],["dc.notes.status","final"],["dc.notes.submitter","PUB_WoS_Import"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","2047-2404"],["dc.title","Left atrial volumetry from routine diagnostic work up prior to pulmonary vein ablation is a good predictor of freedom from atrial fibrillation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","original"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","232"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Herzschrittmachertherapie + Elektrophysiologie"],["dc.bibliographiccitation.lastpage","235"],["dc.bibliographiccitation.volume","28"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Hansen, Claudius"],["dc.contributor.author","Lüthje, Lars"],["dc.contributor.author","Breithardt, Ole A."],["dc.date.accessioned","2021-06-01T10:49:11Z"],["dc.date.available","2021-06-01T10:49:11Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1007/s00399-017-0504-4"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86195"],["dc.language.iso","de"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1435-1544"],["dc.relation.issn","0938-7412"],["dc.title","Malignes Mitralklappenprolapssyndrom bei „idiopathischem“ Kammerflimmern"],["dc.title.translated","Malignant bileaflet mitral valve prolapse syndrome in otherwise idiopathic ventricular fibrillation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","European Heart Journal"],["dc.bibliographiccitation.volume","35"],["dc.contributor.author","Exposito, P. Munoz"],["dc.contributor.author","Seegers, Joachim"],["dc.contributor.author","Luethje, Lars"],["dc.contributor.author","Vollmann, Dirk"],["dc.contributor.author","Hasenfuß, Gerd"],["dc.contributor.author","Zabel, M."],["dc.date.accessioned","2018-11-07T09:35:36Z"],["dc.date.available","2018-11-07T09:35:36Z"],["dc.date.issued","2014"],["dc.format.extent","939"],["dc.identifier.isi","000343001305332"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32422"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.publisher.place","Oxford"],["dc.relation.eventlocation","Barcelona, SPAIN"],["dc.relation.issn","1522-9645"],["dc.relation.issn","0195-668X"],["dc.title","Usefulness of approximate body-surface-potential-mapping (a-bspm) for risk stratification"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]