Now showing 1 - 10 of 48
  • 2000Journal Article
    [["dc.bibliographiccitation.firstpage","42"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Craniofacial Surgery"],["dc.bibliographiccitation.lastpage","45"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Honig, J. F."],["dc.contributor.author","Merten, Hans-Albert"],["dc.date.accessioned","2018-11-07T11:08:06Z"],["dc.date.available","2018-11-07T11:08:06Z"],["dc.date.issued","2000"],["dc.description.abstract","Benign lymphangiomas are encountered frequently in the head and neck region. They may be well circumscribed or diffusely invasive, involving subcutaneous tissue and underlying muscle, and consist of dilated, thin-wall sinuses. Surgical therapy with excision as wide as possible, while taking tare to avoid rupturing the lesion, is the treatment of choice. To simplify complete excision, the authors introduce an intraoperative technique-intralesional injection of fibrin glue. Using this technique over period of 10 years in 27 patients (age range, 7-24 years) they removed successfully intra- and extraoral lymphangiomas. There have been no recurrences. This technique helps avoid rupture of the epithelium and bleeding, and makes it easier to remove lymphangiomas surgically and as completely as possible. This technique reduces recurrence remarkably and ensures successful surgical excision."],["dc.identifier.doi","10.1097/00001665-200011010-00008"],["dc.identifier.isi","000084778600008"],["dc.identifier.pmid","11314099"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/52712"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","1049-2275"],["dc.title","Surgical removal of intra- and extraoral cavernous lymphangiomas using intraoperative-assisted intralesional fibrin glue injections"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2005Journal Article
    [["dc.bibliographiccitation.artnumber","ONS411"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Neurosurgery"],["dc.bibliographiccitation.volume","57"],["dc.contributor.author","Schaller, Bernhard J."],["dc.contributor.author","Gruber, Rudolf Matthias"],["dc.contributor.author","Merten, Hans-Albert"],["dc.contributor.author","Kruschat, Thomas"],["dc.contributor.author","Schliephake, Henning"],["dc.contributor.author","Buchfelder, Michael"],["dc.contributor.author","Ludwig, H.-C."],["dc.date.accessioned","2018-11-07T10:55:32Z"],["dc.date.available","2018-11-07T10:55:32Z"],["dc.date.issued","2005"],["dc.description.abstract","OBJECTIVE: Piezoelectric surgery represents an innovative, ultrasonic surgery technique for performing a safe and effective osteotomy or osteoplasty that contrasts with the traditional hard and soft tissue management methods with rotating instruments. METHODS: Because of its physical and mechanical properties, the definitive clinical advantage of piezoelectric bone surgery with regard to precision cutting lies in the sparing of vital neurovascular bundles or general soft tissue and better visualization of the surgical field, thus suggesting its great safety. Piezoelectric bone surgery has been previously described only in oral and maxillofacial operative procedures in adults. RESULTS: Five children between the age of 6 and 84 months were operated on for craniosynostosis, tethered cord, and an extraconal intraorbital tumor. The usefulness of piezoelectric bone surgery during neurosurgical procedures is presented for these cases. This technique is especially recommended when there are anatomic difficulties because of poor intraoperative visibility or the presence of delicate anatomic structures. CONCLUSION: The present preliminary report (comprising illustrative case reports) demonstrates and introduces for the first time the utility of piezoelectric bone surgery in cranial base and spinal surgery in children. Until now, there has been no documented neurosurgical experience of this technique even in adults."],["dc.identifier.doi","10.1227/01.NEU.0000176700.77461.C9"],["dc.identifier.isi","000208209000069"],["dc.identifier.pmid","16234663"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/49806"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","0148-396X"],["dc.title","PIEZOELECTRIC BONE SURGERY: A REVOLUTIONARY TECHNIQUE FOR MINIMALLY INVASIVE SURGERY IN CRANIAL BASE AND SPINAL SURGERY? TECHNICAL NOTE"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2003Journal Article
    [["dc.bibliographiccitation.firstpage","151"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Mund-, Kiefer- und Gesichtschirurgie"],["dc.bibliographiccitation.lastpage","156"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Patyk, A."],["dc.contributor.author","Wollschläger, B."],["dc.contributor.author","Merten, H. A."],["dc.date.accessioned","2021-06-01T10:49:16Z"],["dc.date.available","2021-06-01T10:49:16Z"],["dc.date.issued","2003"],["dc.identifier.doi","10.1007/s10006-003-0468-x"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86227"],["dc.language.iso","de"],["dc.notes.intern","DOI-Import GROB-425"],["dc.relation.eissn","1434-3940"],["dc.relation.issn","1432-9417"],["dc.title","Memory-Effekt resorbierbarer Polymere"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]
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  • 1997Journal Article
    [["dc.bibliographiccitation.journal","Zahnärztliche Welt ; Zahnärztliche Rundschau ; Zahnärztliche Reform: ZWR"],["dc.bibliographiccitation.volume","106"],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Merten, H. A."],["dc.contributor.author","Hˆnig, J. F."],["dc.contributor.author","Ludwig, A."],["dc.contributor.author","Wiese, K. G."],["dc.date.accessioned","2017-11-21T09:59:19Z"],["dc.date.available","2017-11-21T09:59:19Z"],["dc.date.issued","1997"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/10126"],["dc.language.iso","de"],["dc.notes.status","new -primates"],["dc.title","Temporäre Platzhalter zum Knochenersatz Galskeramik versus Kunsstoff"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]
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  • 2001Journal Article Erratum
    [["dc.bibliographiccitation.firstpage","919"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Acta Neurochirurgica"],["dc.bibliographiccitation.lastpage","925"],["dc.bibliographiccitation.volume","143"],["dc.contributor.author","Verheggen, Raphaela"],["dc.contributor.author","Merten, Hans-Albert"],["dc.date.accessioned","2018-11-07T09:27:36Z"],["dc.date.available","2018-11-07T09:27:36Z"],["dc.date.issued","2001"],["dc.description.abstract","Background. The development of satisfactory cranioplasty mate -rial and technique has been a continuing bio-engineering challenge. Cranial defects resulting from trauma, tumour or infection are most frequently reconstructed with nonviable alloplastic materials. At present, all synthetic or biological materials in the use for human cranioplasty are more or less ideal. Methods. The in vivo properties of a fully resorbable bony substitute - hydroxyapatite cement (HAC, BoneSource (R)) are described in clinical investigations and animal experiments. HAC is prepared from calcium phosphate precursors which are hydrated and harden endothermically at 37 degreesC to form hydroxyapatite. Bone formation and resorption characteristics of HAC are examined in an adult minipig cranial defect model. Findings. Cranial bone integrity has been restored in ten of eleven patients. Radiographic examination 6 months after surgery reveal a successful reconstruction of the skull defects. Sections of the cranial defect site from animals sacrificed at 12, 18 and 40 weeks demonstrate that new bone formation proceeds in HAC filled osseous defects. Histomorphological evaluation of HAC resorption and new bone formation indicates that HAC is nearly completely resorbed within 40 weeks and replaced by new bone with no loss in size or volume. Interpretation. Hydroxyapatite cement (HAC) has an excellent biocompatibility (non-immunogenic and non-toxic), seems to be an optimal implant for cranial reconstruction and provides a biological scaffold for bone formation. However, further studies need to be conducted to determine the long-term stability of HAC."],["dc.identifier.doi","10.1007/s007010170022"],["dc.identifier.isi","000171488700020"],["dc.identifier.pmid","11685624"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30575"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0001-6268"],["dc.title","Correction of skull defects using hydroxyapatite cement (HAC) - Evidence derived from animal experiments and clinical experience"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.subtype","erratum_ja"],["dspace.entity.type","Publication"]]
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  • 2001Journal Article
    [["dc.bibliographiccitation.firstpage","287"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Craniofacial Surgery"],["dc.bibliographiccitation.lastpage","291"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Hönig, Johannes Franz"],["dc.contributor.author","Merten, Hans Albert"],["dc.contributor.author","Ludwig, Hans"],["dc.contributor.author","Bebnke-Mursch, Juliane"],["dc.date.accessioned","2021-06-01T10:46:49Z"],["dc.date.available","2021-06-01T10:46:49Z"],["dc.date.issued","2001"],["dc.description.abstract","Extensive cranioorbital surgery for craniosynostosis in young children can produce excessive blood loss. Thus, to overcome the disadvantage of unappropriated blood loss and translocation of the osteosynthesis material, we performed a subgaleal dissection in infants and compared the subperiosteal with the subgaleal surgical approach in 29 children who underwent surgery for craniosynostosis. The treatment goal of correction of the deformity was accomplished in each ease. Fronto-orbital deformities were significantly improved in all patients. Blood loss was less in the group with subgaleal elevation of the forehead (mean = 163 ml) compared with the subperiosteal group, which had a mean 266 ml blood loss. The subgaleal dissection caused less bleeding and tethering of the advanced bone."],["dc.identifier.doi","10.1097/00001665-200105000-00016"],["dc.identifier.isi","000168481800016"],["dc.identifier.pmid","11358104"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85396"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","1049-2275"],["dc.title","Subgaleal Versus Subperiosteal Dissection in Fronto-Orbital Advancement Procedures"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2002Conference Paper
    [["dc.bibliographiccitation.firstpage","171"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Plastic & Reconstructive Surgery"],["dc.bibliographiccitation.lastpage","180"],["dc.bibliographiccitation.volume","109"],["dc.contributor.author","Kessler, P. A."],["dc.contributor.author","Merten, Hans-Albert"],["dc.contributor.author","Neukam, F. W."],["dc.contributor.author","Wiltfang, J."],["dc.date.accessioned","2018-11-07T10:33:41Z"],["dc.date.available","2018-11-07T10:33:41Z"],["dc.date.issued","2002"],["dc.description.abstract","Callus distraction has become an accepted treatment procedure to lengthen hypoplastic mandibles in humans. For this purpose, extraoral and intraoral devices have been applied successfully. The effects of the distraction vector, distractor stability, and rate and frequency of callus distraction on the regenerating tissues have been examined in various studies. In an experimental animal trial on pigs (n = 12), a newly developed microhydraulic osteodistractor was tested. The animals were evenly assigned to two groups to perform a continuous and noncontinuous osteodistraction of the mandible. Initially, the forces necessary to distract the pig mandibles were recorded from a noncontinuous distraction procedure; the results were then used to perform continuous bone distraction. Besides testing the new distractor, the study proved that in continuous osteodistraction, intramembranous bone regeneration occurred, whereas in noncontinuous osteodistraction the bone regeneration process followed a chondroid ossification. In continuous osteodistraction, the bone regeneration proceeded at a higher speed with the lower distraction forces compared with noncontinuous distraction, thereby reducing the consolidation period. Clinical and microscopical results are presented."],["dc.identifier.doi","10.1097/00006534-200201000-00027"],["dc.identifier.isi","000173102600027"],["dc.identifier.pmid","11786809"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44670"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.publisher.place","Philadelphia"],["dc.relation.conference","69th Annual Meeting of the American-Society-of-Plastic-and-Reconstructive-Surgeons"],["dc.relation.eventlocation","LOS ANGELES, CALIFORNIA"],["dc.relation.issn","0032-1052"],["dc.title","The effects of magnitude and frequency of distraction forces on tissue regeneration in distraction osteogenesis of the mandible"],["dc.type","conference_paper"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2000Journal Article
    [["dc.bibliographiccitation.firstpage","288"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS"],["dc.bibliographiccitation.lastpage","291"],["dc.bibliographiccitation.volume","89"],["dc.contributor.author","Wiltfang, J."],["dc.contributor.author","Schultze-Mosgau, S."],["dc.contributor.author","Merten, Hans-Albert"],["dc.contributor.author","Kessler, P."],["dc.contributor.author","Ludwig, A."],["dc.contributor.author","Engelke, Wilfried G. H."],["dc.date.accessioned","2018-11-07T09:36:00Z"],["dc.date.available","2018-11-07T09:36:00Z"],["dc.date.issued","2000"],["dc.description.abstract","Objective. The aim of our study was a radiographic, endoscopic, and ultrasound follow-up of the maxillary sinus comparing 2 techniques of sinus floor augmentation. Study design. Sonograms, radiographs (Waters' view) of the sinuses, and endoscopy served before and during surgery to evaluate the maxillary sinus. One week after the operation, ultrasound and radiograph follow-up (Waters' view) were carried out. Six months after the operation, we performed an ultrasound follow-up along with uncovering the implants. If any pathologic condition was found, we look another x-ray film of the sinuses, performed another endoscopic examination, or both. Results. In 23 of 63 patients, healing was uneventful. Waters' view revealed opacification of the maxillary sinus 1 week after surgery in 40 cases when the \"window technique' was used. Sinusitis occurred 3 times, as a result of migration of bone chips in 2 patients. We lost 11 of 132 inserted implants during the healing and loading periods. Conclusion. Endoscope-controlled sinus floor augmentation may lower the complication rate in a remaining height of the jaws between 4 and 8 mm. In our group of patients, we proved by endoscopic examination that migration of cancellous bone sequestra was the reason for sinusitis. In case of infected bone grafts with antral symptoms, sinuscopy allowed debridement and removal of a sequestrum."],["dc.identifier.doi","10.1016/S1079-2104(00)70090-4"],["dc.identifier.isi","000085832000007"],["dc.identifier.pmid","10710451"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32513"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Mosby-year Book Inc"],["dc.relation.issn","1079-2104"],["dc.title","Endoscopic and ultrasonographic evaluation of the maxillary sinus after combined sinus floor augmentation and implant insertion"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2009Journal Article
    [["dc.bibliographiccitation.firstpage","175"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Clinical Oral Implants Research"],["dc.bibliographiccitation.lastpage","182"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Gruber, Rudolf Matthias"],["dc.contributor.author","Ludwig, Arwed"],["dc.contributor.author","Merten, Hans-Albert"],["dc.contributor.author","Pippig, Susanne"],["dc.contributor.author","Kramer, Franz-Josef"],["dc.contributor.author","Schliephake, Henning"],["dc.date.accessioned","2018-11-07T08:32:56Z"],["dc.date.available","2018-11-07T08:32:56Z"],["dc.date.issued","2009"],["dc.description.abstract","The aim of this study was to test the hypothesis that recombinant human growth and differentiation factor-5 (rhGDF-5) in combination with a beta-tricalcium phosphate (beta-TCP) scaffold material results in superior bone formation in sinus floor augmentations in miniature pigs compared with a particulated autogenous bone graft combined with the scaffold material. Six adult female Goettingen minipigs underwent a maxillary sinus floor augmentation procedure. In a split-mouth design, the sinus floors were augmented with beta-TCP mixed with autogenous cortical bone chips, in a ratio of approximately 1 : 1, on one side. The contralateral test site was augmented using beta-TCP coated with two concentrations of rhGDF-5 (400 mu g rhGDF-5/g beta-TCP or 800 mu g rhGDF-5/g beta-TCP; three animals in each case). Simultaneously, one dental implant was inserted into each sinus floor augmentation. After 12 weeks, a histological and histomorphometric assessment of non-decalcified histological specimens was made. There were significantly higher mean values of volume density of newly formed bone using beta-TCP coated with two concentrations of rhGDF-5 (400 mu g: 32.9%; 800 mu g: 23.9%) than with the corresponding control (autogenous bone/beta-TCP) (14.6%, 12.9%) (P=0.012, P=0.049). The bone-to-implant contact rates (BIC) were significantly enhanced in test sites (400 mu g: 84.2%; 800 mu g: 69.8%) compared with the corresponding control sites (24.8%, 40.8%) (P=.027, P=.045). rhGDF-5 delivered on beta-TCP significantly enhanced bone formation compared with beta-TCP combined with autogenous bone in sinus lift procedures in miniature pigs. To cite this article:Gruber RM, Ludwig A, Merten H-A, Pippig S, Kramer F-J, Schliephake H. Sinus floor augmentation with recombinant human growth and differentiation factor-5 (rhGDF-5): a pilot study in the Goettingen miniature pig comparing autogenous bone and rhGDF-5. Clin. Oral Impl. Res. 20, 2009; 175-182.doi: 10.1111/j.1600-0501.2008.01628.x."],["dc.description.sponsorship","Scil Technology GmbH"],["dc.identifier.doi","10.1111/j.1600-0501.2008.01628.x"],["dc.identifier.isi","000262509500010"],["dc.identifier.pmid","19077151"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17452"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell Publishing, Inc"],["dc.relation.issn","0905-7161"],["dc.title","Sinus floor augmentation with recombinant human growth and differentiation factor-5 (rhGDF-5): a pilot study in the Goettingen miniature pig comparing autogenous bone and rhGDF-5"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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  • 2005Journal Article
    [["dc.bibliographiccitation.firstpage","52"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Veterinary and Comparative Orthopaedics and Traumatology"],["dc.bibliographiccitation.lastpage","54"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Hauschild, G."],["dc.contributor.author","Merten, Hans-Albert"],["dc.contributor.author","Bader, A."],["dc.contributor.author","Uhr, G."],["dc.contributor.author","Deivick, A."],["dc.contributor.author","Meyer-Lindenberg, Andreas"],["dc.contributor.author","Fehr, M."],["dc.date.accessioned","2018-11-07T08:49:04Z"],["dc.date.available","2018-11-07T08:49:04Z"],["dc.date.issued","2005"],["dc.description.abstract","Grafting of large bone defects caused by trauma or tumor resection still remains a problem to solve. In experimental studies as well as in human dentistry, osteoconduction and biodegradation of the beta-tricalciumphosphate Cerasorb (R) as well as osteoinductive capabilities of platelet rich plasma have been proven. In case of luxation of the right tarsal joint, including a compressive fracture of the forth tarsal bone, the recommended use of autologous cancellous bone to support osseous fusion was replaced by the use of a bioartificial bone graft. Biodegradation of the bone graft was proven clinically and radiographically. Complete osseous fusion of the intertarsal joint occurred. The use of the beta-tricalciumphosphate Cerasorb in combination with platelet rich plasma to support a partial arthrodesis of the tarsal joint in a dog did not impede the healing process but led to full recovery of the patient, indicating that this concept of bioartificial bone grafting could support bone healing."],["dc.identifier.isi","000227617600011"],["dc.identifier.pmid","16594218"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/21368"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Schattauer Gmbh-verlag Medizin Naturwissenschaften"],["dc.relation.issn","0932-0814"],["dc.title","Bioartificial bone grafting: Tarsal joint fusion in a dog using a bioartificial composite bone graft consisting of beta-tricalciumphosphate and platelet rich plasma - A case report"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]
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