Prpic-Schäper, Nikola-Michael

[["dc.bibliographiccitation.firstpage","53"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Development Genes and Evolution"],["dc.bibliographiccitation.lastpage","58"],["dc.bibliographiccitation.volume","219"],["dc.contributor.author","Toegel, Jane Patricia"],["dc.contributor.author","Wimmer, Ernst A."],["dc.contributor.author","Prpic, Nikola-Michael"],["dc.date.accessioned","2018-11-07T08:34:23Z"],["dc.date.available","2018-11-07T08:34:23Z"],["dc.date.issued","2009"],["dc.description.abstract","The Drosophila spineless (ss) gene is regulated downstream of the appendage gene Distal-less (Dll) and is involved in leg and antenna development. Specifically, loss of ss leads to the homeotic transformation of the arista, the distalmost antennal segment, into tarsal identity, and the loss or fusion of distal leg segments. Here we show that the ss homolog from the red flour beetle Tribolium castaneum also homeotically transforms the beetle antenna into leg, but the extent of the transformation is significantly larger than in Drosophila, as the entire antenna (except for the basal antennifer) is transformed into pretarsal, tibiotarsal, and femoral identity; i.e., the transformation comprises the Dll positive area in both appendages. We interpret the antennal phenotype in Tribolium as evidence for a more exclusive role of ss in antennal determination downstream of Dll in the beetle. By contrast, the fact that, in Drosophila ss mutants, only a small portion of the Dll positive area in the antenna is homeotically transformed indicates that Dll uses additional targets to govern the development of the other antennal segments in the fly."],["dc.identifier.doi","10.1007/s00427-008-0265-5"],["dc.identifier.isi","000261787900007"],["dc.identifier.pmid","19030876"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/3537"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17796"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0949-944X"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Loss of spineless function transforms the Tribolium antenna into a thoracic leg with pretarsal, tibiotarsal, and femoral identity"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","716"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","BMC Research Notes"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Quade, Felix S. C."],["dc.contributor.author","Preitz, Beate"],["dc.contributor.author","Prpic, Nikola-Michael"],["dc.date.accessioned","2019-07-09T11:45:59Z"],["dc.date.available","2019-07-09T11:45:59Z"],["dc.date.issued","2018"],["dc.description.abstract","Objective The bleaching, clearing and handling of tiny specimens with soft tissue and cuticular components for confocal laser scanning microscopy is difficult, because after cuticle bleaching and tissue clearing the specimens are virtually invisible. We have adjusted the design of the specimen container described by Smolla et al. (Arthropod Struct Dev 43:175–81, 2014) to handle tiny specimens. Results We describe a perforated and anodised aluminium slide that was designed to hold the distal tips of the pedipalp appendages of the spider Parasteatoda tepidariorum during clearing, and that can then be used directly for confocal laser scanning microscopy. We believe that this slide design will be helpful for others who want to visualise specimens between 500 and 800 µm with confocal laser scanning microscopy."],["dc.identifier.doi","10.1186/s13104-018-3826-3"],["dc.identifier.pmid","30305162"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15365"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59353"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","A perforated anodised aluminium slide for improved specimen clearing and imaging for confocal laser scanning microscopy"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1"],["dc.bibliographiccitation.issue","62"],["dc.bibliographiccitation.journal","BMC Biology"],["dc.bibliographiccitation.lastpage","27"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Schwager, Evelyn E."],["dc.contributor.author","Sharma, Prashant P."],["dc.contributor.author","Clark, Thomas"],["dc.contributor.author","Leite, Daniel J."],["dc.contributor.author","Wierschin, Torsten"],["dc.contributor.author","Pechmann, Matthias"],["dc.contributor.author","Akiyama-Oda, Yasuko"],["dc.contributor.author","Esposito, Lauren"],["dc.contributor.author","Bechsgaard, Jesper"],["dc.contributor.author","Bilde, Trine"],["dc.contributor.author","Buffry, Alexandra D."],["dc.contributor.author","Chao, Hsu"],["dc.contributor.author","Huyen, Dinh"],["dc.contributor.author","Doddapaneni, Harshavardhan"],["dc.contributor.author","Dugan, Shannon"],["dc.contributor.author","Eibner, Cornelius"],["dc.contributor.author","Extavour, Cassandra G."],["dc.contributor.author","Funch, Peter"],["dc.contributor.author","Garb, Jessica"],["dc.contributor.author","Gonzalez, Luis B."],["dc.contributor.author","Gonzalez, Vanessa L."],["dc.contributor.author","Griffiths-Jones, Sam"],["dc.contributor.author","Han, Yi"],["dc.contributor.author","Hayashi, Cheryl"],["dc.contributor.author","Hilbrant, Maarten"],["dc.contributor.author","Hughes, Daniel S. T."],["dc.contributor.author","Janssen, Ralf"],["dc.contributor.author","Lee, Sandra L."],["dc.contributor.author","Maeso, Ignacio"],["dc.contributor.author","Murali, Shwetha C."],["dc.contributor.author","Muzny, Donna M."],["dc.contributor.author","Nunes da Fonseca, Rodrigo"],["dc.contributor.author","Paese, Christian L. B."],["dc.contributor.author","Qu, Jiaxin"],["dc.contributor.author","Ronshaugen, Matthew"],["dc.contributor.author","Schomburg, Christoph"],["dc.contributor.author","Schönauer, Anna"],["dc.contributor.author","Stollewerk, Angelika"],["dc.contributor.author","Torres-Oliva, Montserrat"],["dc.contributor.author","Turetzek, Natascha"],["dc.contributor.author","Vanthournout, Bram"],["dc.contributor.author","Werren, John H."],["dc.contributor.author","Wolff, Carsten"],["dc.contributor.author","Worley, Kim C."],["dc.contributor.author","Bucher, Gregor"],["dc.contributor.author","Gibbs, Richard A."],["dc.contributor.author","Coddington, Jonathan"],["dc.contributor.author","Oda, Hiroki"],["dc.contributor.author","Stanke, Mario"],["dc.contributor.author","Ayoub, Nadia A."],["dc.contributor.author","Prpic, Nikola-Michael"],["dc.contributor.author","Flot, Jean-Francois"],["dc.contributor.author","Posnien, Nico"],["dc.contributor.author","Richards, Stephen"],["dc.contributor.author","McGregor, Alistair P."],["dc.date.accessioned","2019-07-09T11:44:25Z"],["dc.date.available","2019-07-09T11:44:25Z"],["dc.date.issued","2017"],["dc.description.abstract","The duplication of genes can occur through various mechanisms and is thought to make a major contribution to the evolutionary diversification of organisms. There is increasing evidence for a large-scale duplication of genes in some chelicerate lineages including two rounds of whole genome duplication (WGD) in horseshoe crabs. To investigate this further, we sequenced and analyzed the genome of the common house spider Parasteatoda tepidariorum. We found pervasive duplication of both coding and non-coding genes in this spider, including two clusters of Hox genes. Analysis of synteny conservation across the P. tepidariorum genome suggests that there has been an ancient WGD in spiders. Comparison with the genomes of other chelicerates, including that of the newly sequenced bark scorpion Centruroides sculpturatus, suggests that this event occurred in the common ancestor of spiders and scorpions, and is probably independent of the WGDs in horseshoe crabs. Furthermore, characterization of the sequence and expression of the Hox paralogs in P. tepidariorum suggests that many have been subject to neo-functionalization and/or sub-functionalization since their duplication. Our results reveal that spiders and scorpions are likely the descendants of a polyploid ancestor that lived more than 450 MYA. Given the extensive morphological diversity and ecological adaptations found among these animals, rivaling those of vertebrates, our study of the ancient WGD event in Arachnopulmonata provides a new comparative platform to explore common and divergent evolutionary outcomes of polyploidization events across eukaryotes."],["dc.identifier.doi","10.1186/s12915-017-0399-x"],["dc.identifier.pmid","28756775"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/15127"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/59010"],["dc.notes.intern","Merged from goescholar"],["dc.notes.intern","In goescholar not merged with http://resolver.sub.uni-goettingen.de/purl?gs-1/14757 but duplicate"],["dc.rights","CC BY 4.0"],["dc.rights.access","openAccess"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","The house spider genome reveals an ancient whole-genome duplication during arachnid evolution"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","399"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","Development Genes and Evolution"],["dc.bibliographiccitation.lastpage","407"],["dc.bibliographiccitation.volume","219"],["dc.contributor.author","Kittelmann, Maike"],["dc.contributor.author","Schinko, Johannes B."],["dc.contributor.author","Winkler, Marco"],["dc.contributor.author","Bucher, Gregor"],["dc.contributor.author","Wimmer, Ernst A."],["dc.contributor.author","Prpic, Nikola-Michael"],["dc.date.accessioned","2018-11-07T11:25:55Z"],["dc.date.available","2018-11-07T11:25:55Z"],["dc.date.issued","2009"],["dc.description.abstract","The genetic control of leg development is well characterized in the fly Drosophila melanogaster. These control mechanisms, however, must differ to some degree between different insect species to account for the morphological diversity of thoracic legs in the insects. The legs of the flour beetle Tribolium castaneum differ from the Drosophila legs in their developmental mode as well as in their specific morphology especially at the larval stage. In order to identify genes involved in the morphogenesis of the Tribolium larval legs, we have analyzed EGFP enhancer trap lines of Tribolium. We have identified the zfh2 gene as a novel factor required for normal leg development in Tribolium. RNA interference with zfh2 function leads to two alternative classes of leg phenotype. The loss of a leg segment boundary and the generation of ectopic outgrowths in one class of phenotype suggest a role in leg segmentation and segment growth. The malformation of the pretarsal claw in the second class of phenotype suggests a role in distal development and the morphogenesis of the claw-shaped morphology of the pretarsus. This suggests that zfh2 is involved in the regulation of an unidentified target gene in a concentration-dependent manner. Our results demonstrate that enhancer trap screens in T. castaneum have the potential to identify novel gene functions regulating specific developmental processes."],["dc.identifier.doi","10.1007/s00427-009-0303-y"],["dc.identifier.isi","000271397600002"],["dc.identifier.pmid","19760181"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/3758"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56738"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0949-944X"],["dc.rights.access","openAccess"],["dc.subject.ddc","570"],["dc.title","Insertional mutagenesis screening identifies the zinc finger homeodomain 2 (zfh2) gene as a novel factor required for embryonic leg development in Tribolium castaneum"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","469"],["dc.bibliographiccitation.issue","9-10"],["dc.bibliographiccitation.journal","Development Genes and Evolution"],["dc.bibliographiccitation.lastpage","479"],["dc.bibliographiccitation.volume","219"],["dc.contributor.author","Grossmann, Daniela"],["dc.contributor.author","Scholten, Johannes"],["dc.contributor.author","Prpic, Nikola-Michael"],["dc.date.accessioned","2018-11-07T11:23:28Z"],["dc.date.available","2018-11-07T11:23:28Z"],["dc.date.issued","2009"],["dc.description.abstract","The gene wingless (wg) in Drosophila is an important factor in leg development. During embryonic development wg is involved in the allocation of the limb primordia. During imaginal disk development wg is involved in distal development and it has a separate role in ventral development. The expression pattern of wg is highly conserved in all arthropods (comprising data from insects, myriapods, crustaceans, and chelicerates), suggesting that its function in leg development is also conserved. However, recent work in other insects (e.g. the milkweed bug Oncopeltus fasciatus) argued against a role of wg in leg development. We have studied the role of wg in leg development of the flour beetle Tribolium castaneum. Using stage-specific staggered embryonic RNAi in wild-type and transgenic EGFP expressing enhancer trap lines we are able to demonstrate separable functions of Tribolium wg in distal and in ventral leg development. The distal role affects all podomeres distal to the coxa, whereas the ventral role is restricted to cells along the ventral midline of the legs. In addition, severe leg defects after injection into early embryonic stages are evidence that wg is also involved in proximal development and limb allocation in Tribolium. Our data suggest that the roles of wg in leg development are highly conserved in the holometabolous insects. Further studies will reveal the degree of conservation in other arthropod groups."],["dc.description.sponsorship","Deutsche Forschungsgemeinschaft [PR 1109/1-1]"],["dc.identifier.doi","10.1007/s00427-009-0310-z"],["dc.identifier.isi","000273978900004"],["dc.identifier.pmid","20024581"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/4037"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/56205"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","1432-041X"],["dc.relation.issn","0949-944X"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Separable functions of wingless in distal and ventral patterning of the Tribolium leg"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e104885"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Posnien, Nico"],["dc.contributor.author","Zeng, Victor"],["dc.contributor.author","Schwager, Evelyn E."],["dc.contributor.author","Pechmann, Matthias"],["dc.contributor.author","Hilbrant, Maarten"],["dc.contributor.author","Keefe, Joseph D."],["dc.contributor.author","Damen, Wim G. M."],["dc.contributor.author","Prpic, Nikola-Michael"],["dc.contributor.author","McGregor, Alistair P."],["dc.contributor.author","Extavour, Cassandra G."],["dc.date.accessioned","2018-11-07T09:36:37Z"],["dc.date.available","2018-11-07T09:36:37Z"],["dc.date.issued","2014"],["dc.description.abstract","Parasteatoda tepidariorum is an increasingly popular model for the study of spider development and the evolution of development more broadly. However, fully understanding the regulation and evolution of P. tepidariorum development in comparison to other animals requires a genomic perspective. Although research on P. tepidariorum has provided major new insights, gene analysis to date has been limited to candidate gene approaches. Furthermore, the few available EST collections are based on embryonic transcripts, which have not been systematically annotated and are unlikely to contain transcripts specific to post-embryonic stages of development. We therefore generated cDNA from pooled embryos representing all described embryonic stages, as well as post-embryonic stages including nymphs, larvae and adults, and using Illumina HiSeq technology obtained a total of 625,076,514 100-bp paired end reads. We combined these data with 24,360 ESTs available in GenBank, and 1,040,006 reads newly generated from 454 pyrosequencing of a mixed-stage embryo cDNA library. The combined sequence data were assembled using a custom de novo assembly strategy designed to optimize assembly product length, number of predicted transcripts, and proportion of raw reads incorporated into the assembly. The de novo assembly generated 446,427 contigs with an N50 of 1,875 bp. These sequences obtained 62,799 unique BLAST hits against the NCBI non-redundant protein data base, including putative orthologs to 8,917 Drosophila melanogaster genes based on best reciprocal BLAST hit identity compared with the D. melanogaster proteome. Finally, we explored the utility of the transcriptome for RNA-Seq studies, and showed that this resource can be used as a mapping scaffold to detect differential gene expression in different cDNA libraries. This resource will therefore provide a platform for future genomic, gene expression and functional approaches using P. tepidariorum."],["dc.description.sponsorship","Open Access Publikationsfonds 2014"],["dc.identifier.doi","10.1371/journal.pone.0104885"],["dc.identifier.isi","000340900600099"],["dc.identifier.pmid","25118601"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/10635"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/32658"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 2.5"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.5"],["dc.title","A Comprehensive Reference Transcriptome Resource for the Common House Spider Parasteatoda tepidariorum"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","5"],["dc.bibliographiccitation.journal","EvoDevo"],["dc.bibliographiccitation.volume","2"],["dc.contributor.author","Janssen, Ralf"],["dc.contributor.author","Budd, Graham E."],["dc.contributor.author","Prpic, Nikola-Michael"],["dc.contributor.author","Damen, Wim G. M."],["dc.date.accessioned","2018-11-07T09:00:09Z"],["dc.date.available","2018-11-07T09:00:09Z"],["dc.date.issued","2011"],["dc.description.abstract","Background: Segmentation is a hallmark of the arthropods; most knowledge about the molecular basis of arthropod segmentation comes from work on the fly Drosophila melanogaster. In this species a hierarchic cascade of segmentation genes subdivides the blastoderm stepwise into single segment wide regions. However, segmentation in the fly is a derived feature since all segments form virtually simultaneously. Conversely, in the vast majority of arthropods the posterior segments form one at a time from a posterior pre-segmental zone. The pair rule genes (PRGs) comprise an important level of the Drosophila segmentation gene cascade and are indeed the first genes that are expressed in typical transverse stripes in the early embryo. Information on expression and function of PRGs outside the insects, however, is scarce. Results: Here we present the expression of the pair rule gene orthologs in the pill millipede Glomeris marginata (Myriapoda: Diplopoda). We find evidence that these genes are involved in segmentation and that components of the hierarchic interaction of the gene network as found in insects may be conserved. We further provide evidence that segments are formed in a single-segment periodicity rather than in pairs of two like in another myriapod, the centipede Strigamia maritima. Finally we show that decoupling of dorsal and ventral segmentation in Glomeris appears already at the level of the PRGs. Conclusions: Although the pair rule gene network is partially conserved among insects and myriapods, some aspects of PRG interaction are, as suggested by expression pattern analysis, convergent, even within the Myriapoda. Conserved expression patterns of PRGs in insects and myriapods, however, may represent ancestral features involved in segmenting the arthropod ancestor."],["dc.identifier.doi","10.1186/2041-9139-2-5"],["dc.identifier.isi","000310693900005"],["dc.identifier.pmid","21352542"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/5995"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/24084"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Biomed Central Ltd"],["dc.relation.issn","2041-9139"],["dc.rights","CC BY 2.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/2.0"],["dc.title","Expression of myriapod pair rule gene orthologs"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Genome Biology"],["dc.bibliographiccitation.volume","21"],["dc.contributor.author","Thomas, Gregg W. C."],["dc.contributor.author","Dohmen, Elias"],["dc.contributor.author","Hughes, Daniel S. T."],["dc.contributor.author","Murali, Shwetha C."],["dc.contributor.author","Poelchau, Monica"],["dc.contributor.author","Glastad, Karl"],["dc.contributor.author","Anstead, Clare A."],["dc.contributor.author","Ayoub, Nadia A."],["dc.contributor.author","Batterham, Phillip"],["dc.contributor.author","Bellair, Michelle"],["dc.contributor.author","Binford, Greta J."],["dc.contributor.author","Chao, Hsu"],["dc.contributor.author","Chen, Yolanda H."],["dc.contributor.author","Childers, Christopher"],["dc.contributor.author","Dinh, Huyen"],["dc.contributor.author","Doddapaneni, Harsha Vardhan"],["dc.contributor.author","Duan, Jian J."],["dc.contributor.author","Dugan, Shannon"],["dc.contributor.author","Esposito, Lauren A."],["dc.contributor.author","Friedrich, Markus"],["dc.contributor.author","Garb, Jessica"],["dc.contributor.author","Gasser, Robin B."],["dc.contributor.author","Goodisman, Michael A. D."],["dc.contributor.author","Gundersen-Rindal, Dawn E."],["dc.contributor.author","Han, Yi"],["dc.contributor.author","Handler, Alfred M."],["dc.contributor.author","Hatakeyama, Masatsugu"],["dc.contributor.author","Hering, Lars"],["dc.contributor.author","Hunter, Wayne B."],["dc.contributor.author","Ioannidis, Panagiotis"],["dc.contributor.author","Jayaseelan, Joy C."],["dc.contributor.author","Kalra, Divya"],["dc.contributor.author","Khila, Abderrahman"],["dc.contributor.author","Korhonen, Pasi K."],["dc.contributor.author","Lee, Carol Eunmi"],["dc.contributor.author","Lee, Sandra L."],["dc.contributor.author","Li, Yiyuan"],["dc.contributor.author","Lindsey, Amelia R. I."],["dc.contributor.author","Mayer, Georg"],["dc.contributor.author","McGregor, Alistair P."],["dc.contributor.author","McKenna, Duane D."],["dc.contributor.author","Misof, Bernhard"],["dc.contributor.author","Munidasa, Mala"],["dc.contributor.author","Munoz-Torres, Monica"],["dc.contributor.author","Muzny, Donna M."],["dc.contributor.author","Niehuis, Oliver"],["dc.contributor.author","Osuji-Lacy, Nkechinyere"],["dc.contributor.author","Palli, Subba R."],["dc.contributor.author","Panfilio, Kristen A."],["dc.contributor.author","Pechmann, Matthias"],["dc.contributor.author","Perry, Trent"],["dc.contributor.author","Peters, Ralph S."],["dc.contributor.author","Poynton, Helen C."],["dc.contributor.author","Prpic, Nikola-Michael"],["dc.contributor.author","Qu, Jiaxin"],["dc.contributor.author","Rotenberg, Dorith"],["dc.contributor.author","Schal, Coby"],["dc.contributor.author","Schoville, Sean D."],["dc.contributor.author","Scully, Erin D."],["dc.contributor.author","Skinner, Evette"],["dc.contributor.author","Sloan, Daniel B."],["dc.contributor.author","Stouthamer, Richard"],["dc.contributor.author","Strand, Michael R."],["dc.contributor.author","Szucsich, Nikolaus U."],["dc.contributor.author","Wijeratne, Asela"],["dc.contributor.author","Young, Neil D."],["dc.contributor.author","Zattara, Eduardo E."],["dc.contributor.author","Benoit, Joshua B."],["dc.contributor.author","Zdobnov, Evgeny M."],["dc.contributor.author","Pfrender, Michael E."],["dc.contributor.author","Hackett, Kevin J."],["dc.contributor.author","Werren, John H."],["dc.contributor.author","Worley, Kim C."],["dc.contributor.author","Gibbs, Richard A."],["dc.contributor.author","Chipman, Ariel D."],["dc.contributor.author","Waterhouse, Robert M."],["dc.contributor.author","Bornberg-Bauer, Erich"],["dc.contributor.author","Hahn, Matthew W."],["dc.contributor.author","Richards, Stephen"],["dc.date.accessioned","2020-12-10T18:39:05Z"],["dc.date.available","2020-12-10T18:39:05Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1186/s13059-019-1925-7"],["dc.identifier.eissn","1474-760X"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17144"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77536"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Gene content evolution in the arthropods"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","333"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Development Genes and Evolution"],["dc.bibliographiccitation.lastpage","339"],["dc.bibliographiccitation.volume","218"],["dc.contributor.author","Prpic, Nikola-Michael"],["dc.contributor.author","Telford, Maximilian J."],["dc.date.accessioned","2018-11-07T11:14:22Z"],["dc.date.available","2018-11-07T11:14:22Z"],["dc.date.issued","2008"],["dc.description.abstract","In Drosophila leg development, the extradenticle (exd) gene is expressed ubiquitously and its co-factor homothorax (hth) is restricted to the proximal leg portion. This condition is conserved in other insect species but is reversed in chelicerates and myriapods. As the region of co-expression does not differ in the two groups and transcripts from both are necessary for function, this difference in expression is likely to be functionally neutral. Here, we report the expression patterns of exd and hth in a crustacean, the amphipod shrimp Parhyale hawaiensis. The patterns in P. hawaiensis are similar to the insect patterns, supporting the close relationship between crustaceans and insects in the taxon Tetraconata. However, mRNA expression of exd in P. hawaiensis is weak in the distal leg parts, thus being intermediate between the complete lack of distal exd expression in chelicerates and myriapods and the strong distal exd expression in insects. Our data suggest that the reversal of the gene expression regulation of hth and exd occurred in the pancrustacean lineage."],["dc.description.sponsorship","Biotechnology and Biological Sciences Research Council [BBS/B/0675X]"],["dc.identifier.doi","10.1007/s00427-008-0221-4"],["dc.identifier.isi","000256319700005"],["dc.identifier.pmid","18504609"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/3535"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/54111"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Springer"],["dc.relation.issn","0949-944X"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Expression of homothorax and extradenticle mRNA in the legs of the crustacean Parhyale hawaiensis: evidence for a reversal of gene expression regulation in the pancrustacean lineage"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","189"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Development Genes and Evolution"],["dc.bibliographiccitation.lastpage","198"],["dc.bibliographiccitation.volume","219"],["dc.contributor.author","Pechmann, Matthias"],["dc.contributor.author","Prpic, Nikola Michael"],["dc.date.accessioned","2018-11-07T08:30:59Z"],["dc.date.available","2018-11-07T08:30:59Z"],["dc.date.issued","2009"],["dc.description.abstract","Pattern formation by the genes dachshund (dac), Distal-less (Dll), extradenticle (exd) and homothorax (hth) in spider appendages has been studied previously only in members of the higher spiders (Araneomorphae). In order to study the diversity and conservation of pattern formation in spiders as a whole, we studied homologs of these genes in embryos of the bird spider Acanthoscurria geniculata, which belongs to the Mygalomorphae, a more primitive spider group. We show that the patterns of dac and Dll are largely conserved in all spiders studied so far. We find a duplication of hth and exd genes as previously identified in the higher spider Cupiennius salei. These data suggest that pattern formation shows little diversity in all spiders, including the duplication of hth and exd that likely occurred before the split of Mygalomorphae and Araneomorphae. We also find that the legs and pedipalps bear endites of which only the pedipalpal endite expresses Dll and is retained in the adult. Similarly, the limb buds of the posterior spinnerets express Dll and become segmented appendages in the adult, whereas the anterior spinnerets lack Dll expression and are absent in postembryonic stages. In both cases, the expression of Dll or the lack of it indicates structures which will be retained as adult traits or rudimentary structures that degenerate, respectively. The presence of embryonic rudiments of leg endites in Acanthoscurria and the leg-like pattern formation in the posterior spinnerets are interpreted as primitive traits that have been lost in the Araneomorphae."],["dc.description.sponsorship","German Research Council [PR1109/1-1]"],["dc.identifier.doi","10.1007/s00427-009-0279-7"],["dc.identifier.isi","000265306600002"],["dc.identifier.pmid","19266215"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/3534"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/17019"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","1432-041X"],["dc.relation.issn","0949-944X"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Appendage patterning in the South American bird spider Acanthoscurria geniculata (Araneae: Mygalomorphae)"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]