Schneider, Anja

[["dc.bibliographiccitation.firstpage","601"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Neurobiology of Aging"],["dc.bibliographiccitation.lastpage","607"],["dc.bibliographiccitation.volume","36"],["dc.contributor.author","Popp, Julius"],["dc.contributor.author","Wolfsgruber, Steffen"],["dc.contributor.author","Heuser, Isabella"],["dc.contributor.author","Peters, Oliver"],["dc.contributor.author","Hüll, Michael"],["dc.contributor.author","Schröder, Johannes"],["dc.contributor.author","Möller, Hans-Jürgen"],["dc.contributor.author","Lewczuk, Piotr"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Jahn, Holger"],["dc.contributor.author","Luckhaus, Christian"],["dc.contributor.author","Perneczky, Robert"],["dc.contributor.author","Frölich, Lutz"],["dc.contributor.author","Wagner, Michael"],["dc.contributor.author","Maier, Wolfgang"],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Kornhuber, Johannes"],["dc.contributor.author","Jessen, Frank"],["dc.date.accessioned","2017-09-07T11:44:32Z"],["dc.date.available","2017-09-07T11:44:32Z"],["dc.date.issued","2015"],["dc.description.abstract","Increased peripheral and central nervous system cortisol levels have been reported in Alzheimer's disease (AD) and may reflect dysfunction of cerebral components of the hypothalamic-pituitary-adrenal (HPA) axis. However, brain exposure to high cortisol concentrations may also accelerate disease progression and cognitive decline. The objectives of this study were to investigate whether HPA-axis dysregulation occurs at early clinical stages of AD and whether plasma and CSF cortisol levels are associated with clinical disease progression. Morning plasma and CSF cortisol concentrations were obtained from the subjects with AD dementia, mild cognitive impairment of AD type (MCI-AD), MCI of other type (MCI-O), and controls with normal cognition included in a multicenter study from the German Dementia Competence Network. A clinical and neuropsychological follow-up was performed in a subgroup of participants with MCI-AD, MCI-O, and AD dementia. CSF cortisol concentrations were increased in the subjects with AD dementia or MCI-AD compared with subjects with MCI-O or normal cognition. After controlling for possible confounders including CSF measures of amyloid beta1–42 and total tau, higher baseline CSF cortisol levels were associated with faster clinical worsening and cognitive decline in MCI-AD. The findings suggest that HPA-axis dysregulation occurs at the MCI stage of AD and may accelerate disease progression and cognitive decline."],["dc.identifier.doi","10.1016/j.neurobiolaging.2014.10.031"],["dc.identifier.gro","3151692"],["dc.identifier.pmid","25435336"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/8511"],["dc.language.iso","en"],["dc.notes.status","final"],["dc.notes.submitter","chake"],["dc.relation.issn","0197-4580"],["dc.title","Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","945709"],["dc.bibliographiccitation.journal","Frontiers in Psychology"],["dc.bibliographiccitation.volume","13"],["dc.contributor.affiliation","Böttcher, Adriana; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Zarucha, Alexis; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Köbe, Theresa; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Gaubert, Malo; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Höppner, Angela; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Altenstein, Slawek; 3German Center for Neurodegenerative Diseases, Berlin, Germany"],["dc.contributor.affiliation","Bartels, Claudia; 5Department of Psychiatry and Psychotherapy, University Medical Center, University of Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Buerger, Katharina; 6Institute for Stroke and Dementia Research, University Hospital, LMU Munich, Munich, Germany"],["dc.contributor.affiliation","Dechent, Peter; 8MR-Research in Neurology and Psychiatry, Georg-August-University Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Dobisch, Laura; 9German Center for Neurodegenerative Diseases, Magdeburg, Germany"],["dc.contributor.affiliation","Ewers, Michael; 7German Center for Neurodegenerative Diseases, Munich, Germany"],["dc.contributor.affiliation","Fliessbach, Klaus; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Freiesleben, Silka Dawn; 4Department of Psychiatry, Charité – Universitätsmedizin Berlin, Berlin, Germany"],["dc.contributor.affiliation","Frommann, Ingo; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Haynes, John Dylan; 13Bernstein Center for Computational Neuroscience, Charité – Universitätsmedizin, Berlin, Germany"],["dc.contributor.affiliation","Janowitz, Daniel; 6Institute for Stroke and Dementia Research, University Hospital, LMU Munich, Munich, Germany"],["dc.contributor.affiliation","Kilimann, Ingo; 14German Center for Neurodegenerative Diseases, Rostock, Germany"],["dc.contributor.affiliation","Kleineidam, Luca; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Laske, Christoph; 16German Center for Neurodegenerative Diseases, Tübingen, Germany"],["dc.contributor.affiliation","Maier, Franziska; 18Department of Psychiatry, Faculty of Medicine, University of Cologne, Cologne, Germany"],["dc.contributor.affiliation","Metzger, Coraline; 9German Center for Neurodegenerative Diseases, Magdeburg, Germany"],["dc.contributor.affiliation","Munk, Matthias H. J.; 16German Center for Neurodegenerative Diseases, Tübingen, Germany"],["dc.contributor.affiliation","Perneczky, Robert; 7German Center for Neurodegenerative Diseases, Munich, Germany"],["dc.contributor.affiliation","Peters, Oliver; 3German Center for Neurodegenerative Diseases, Berlin, Germany"],["dc.contributor.affiliation","Priller, Josef; 3German Center for Neurodegenerative Diseases, Berlin, Germany"],["dc.contributor.affiliation","Rauchmann, Boris-Stephan; 23Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany"],["dc.contributor.affiliation","Roy, Nina; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Scheffler, Klaus; 25Department for Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany"],["dc.contributor.affiliation","Schneider, Anja; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Spottke, Annika; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Teipel, Stefan J.; 14German Center for Neurodegenerative Diseases, Rostock, Germany"],["dc.contributor.affiliation","Wiltfang, Jens; 5Department of Psychiatry and Psychotherapy, University Medical Center, University of Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Wolfsgruber, Steffen; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Yakupov, Renat; 9German Center for Neurodegenerative Diseases, Magdeburg, Germany"],["dc.contributor.affiliation","Düzel, Emrah; 9German Center for Neurodegenerative Diseases, Magdeburg, Germany"],["dc.contributor.affiliation","Jessen, Frank; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Röske, Sandra; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Wagner, Michael; 11German Center for Neurodegenerative Diseases, Bonn, Germany"],["dc.contributor.affiliation","Kempermann, Gerd; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.affiliation","Wirth, Miranka; 1German Center for Neurodegenerative Diseases, Dresden, Germany"],["dc.contributor.author","Böttcher, Adriana"],["dc.contributor.author","Zarucha, Alexis"],["dc.contributor.author","Köbe, Theresa"],["dc.contributor.author","Gaubert, Malo"],["dc.contributor.author","Höppner, Angela"],["dc.contributor.author","Altenstein, Slawek"],["dc.contributor.author","Bartels, Claudia"],["dc.contributor.author","Buerger, Katharina"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Dobisch, Laura"],["dc.contributor.author","Wirth, Miranka"],["dc.contributor.author","Ewers, Michael"],["dc.contributor.author","Fliessbach, Klaus"],["dc.contributor.author","Freiesleben, Silka Dawn"],["dc.contributor.author","Frommann, Ingo"],["dc.contributor.author","Haynes, John Dylan"],["dc.contributor.author","Janowitz, Daniel"],["dc.contributor.author","Kilimann, Ingo"],["dc.contributor.author","Kleineidam, Luca"],["dc.contributor.author","Laske, Christoph"],["dc.contributor.author","Maier, Franziska"],["dc.contributor.author","Metzger, Coraline"],["dc.contributor.author","Munk, Matthias H. J."],["dc.contributor.author","Perneczky, Robert"],["dc.contributor.author","Peters, Oliver"],["dc.contributor.author","Priller, Josef"],["dc.contributor.author","Rauchmann, Boris-Stephan"],["dc.contributor.author","Roy, Nina"],["dc.contributor.author","Scheffler, Klaus"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Spottke, Annika"],["dc.contributor.author","Teipel, Stefan J."],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Wolfsgruber, Steffen"],["dc.contributor.author","Yakupov, Renat"],["dc.contributor.author","Düzel, Emrah"],["dc.contributor.author","Jessen, Frank"],["dc.contributor.author","Röske, Sandra"],["dc.contributor.author","Wagner, Michael"],["dc.contributor.author","Kempermann, Gerd"],["dc.date.accessioned","2022-10-04T10:21:56Z"],["dc.date.available","2022-10-04T10:21:56Z"],["dc.date.issued","2022"],["dc.date.updated","2022-11-11T13:14:36Z"],["dc.description.abstract","Regular musical activity as a complex multimodal lifestyle activity is proposed to be protective against age-related cognitive decline and Alzheimer’s disease. This cross-sectional study investigated the association and interplay between musical instrument playing during life, multi-domain cognitive abilities and brain morphology in older adults (OA) from the DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE) study. Participants reporting having played a musical instrument across three life periods (\r\n n\r\n = 70) were compared to controls without a history of musical instrument playing (\r\n n\r\n = 70), well-matched for reserve proxies of education, intelligence, socioeconomic status and physical activity. Participants with musical activity outperformed controls in global cognition, working memory, executive functions, language, and visuospatial abilities, with no effects seen for learning and memory. The musically active group had greater gray matter volume in the somatosensory area, but did not differ from controls in higher-order frontal, temporal, or hippocampal volumes. However, the association between gray matter volume in distributed frontal-to-temporal regions and cognitive abilities was enhanced in participants with musical activity compared to controls. We show that playing a musical instrument during life relates to better late-life cognitive abilities and greater brain capacities in OA. Musical activity may serve as a multimodal enrichment strategy that could help preserve cognitive and brain health in late life. Longitudinal and interventional studies are needed to support this notion."],["dc.identifier.doi","10.3389/fpsyg.2022.945709"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/114545"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-600"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","1664-1078"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0/"],["dc.title","Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e1134"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Neurology"],["dc.bibliographiccitation.lastpage","e1143"],["dc.bibliographiccitation.volume","95"],["dc.contributor.author","Wolfsgruber, Steffen"],["dc.contributor.author","Kleineidam, Luca"],["dc.contributor.author","Guski, Jannis"],["dc.contributor.author","Polcher, Alexandra"],["dc.contributor.author","Frommann, Ingo"],["dc.contributor.author","Roeske, Sandra"],["dc.contributor.author","Spruth, Eike Jakob"],["dc.contributor.author","Franke, Christiana"],["dc.contributor.author","Priller, Josef"],["dc.contributor.author","Kilimann, Ingo"],["dc.contributor.author","Teipel, Stefan"],["dc.contributor.author","Buerger, Katharina"],["dc.contributor.author","Janowitz, Daniel"],["dc.contributor.author","Laske, Christoph"],["dc.contributor.author","Buchmann, Martina"],["dc.contributor.author","Peters, Oliver"],["dc.contributor.author","Menne, Felix"],["dc.contributor.author","Fuentes Casan, Manuel"],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Bartels, Claudia"],["dc.contributor.author","Düzel, Emrah"],["dc.contributor.author","Metzger, Coraline"],["dc.contributor.author","Glanz, Wenzel"],["dc.contributor.author","Thelen, Manuela"],["dc.contributor.author","Spottke, Annika"],["dc.contributor.author","Ramirez, Alfredo"],["dc.contributor.author","Kofler, Barbara"],["dc.contributor.author","Fließbach, Klaus"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Heneka, Michael T."],["dc.contributor.author","Brosseron, Frederic"],["dc.contributor.author","Meiberth, Dix"],["dc.contributor.author","Jessen, Frank"],["dc.contributor.author","Wagner, Michael"],["dc.date.accessioned","2021-04-14T08:32:45Z"],["dc.date.available","2021-04-14T08:32:45Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1212/WNL.0000000000010142"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/84007"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1526-632X"],["dc.relation.issn","0028-3878"],["dc.title","Minor neuropsychological deficits in patients with subjective cognitive decline"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Frontiers in Aging Neuroscience"],["dc.bibliographiccitation.volume","13"],["dc.contributor.affiliation","Hansen, Niels; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.affiliation","Singh, Aditya; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.affiliation","Bartels, Claudia; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.affiliation","Brosseron, Frederic; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Buerger, Katharina; 5German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany"],["dc.contributor.affiliation","Cetindag, Arda C.; 7Berlin Institute of Health, Institute of Psychiatry and Psychotherapy, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany"],["dc.contributor.affiliation","Dobisch, Laura; 9German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany"],["dc.contributor.affiliation","Dechent, Peter; 10MR-Research in Neurology and Psychiatry, University Medical Center Göttingen, Göttingen, Germany"],["dc.contributor.affiliation","Ertl-Wagner, Birgit B.; 11Institute for Clinical Radiology, Ludwig-Maximilians-University, Munich, Germany"],["dc.contributor.affiliation","Fliessbach, Klaus; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Haynes, John D.; 12Bernstein Center for Computational Neuroscience, Charité—Universitätsmedizin, Berlin, Germany"],["dc.contributor.affiliation","Heneka, Michael T.; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Janowitz, Daniel; 6Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany"],["dc.contributor.affiliation","Kilimann, Ingo; 13German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany"],["dc.contributor.affiliation","Laske, Christoph; 15German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany"],["dc.contributor.affiliation","Metzger, Coraline D.; 9German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany"],["dc.contributor.affiliation","Munk, Matthias H.; 15German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany"],["dc.contributor.affiliation","Peters, Oliver; 7Berlin Institute of Health, Institute of Psychiatry and Psychotherapy, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany"],["dc.contributor.affiliation","Priller, Josef; 8German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany"],["dc.contributor.affiliation","Roy, Nina; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Scheffler, Klaus; 21Department for Biomedical Magnetic Resonance, University of Tübingen, Tübingen, Germany"],["dc.contributor.affiliation","Schneider, Anja; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Spottke, Annika; 3German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"],["dc.contributor.affiliation","Spruth, Eike J.; 8German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany"],["dc.contributor.affiliation","Teipel, Stefan; 13German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany"],["dc.contributor.affiliation","Tscheuschler, Maike; 23Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany"],["dc.contributor.affiliation","Vukovich, Ruth; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.affiliation","Wiltfang, Jens; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.affiliation","Duezel, Emrah; 9German Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany"],["dc.contributor.affiliation","Jessen, Frank; 23Department of Psychiatry and Psychotherapy, University of Cologne, Medical Faculty, Cologne, Germany"],["dc.contributor.affiliation","Goya-Maldonado, Roberto; 1Department of Psychiatry and Psychotherapy, Göttingen, Germany"],["dc.contributor.author","Hansen, Niels"],["dc.contributor.author","Singh, Aditya"],["dc.contributor.author","Bartels, Claudia"],["dc.contributor.author","Brosseron, Frederic"],["dc.contributor.author","Buerger, Katharina"],["dc.contributor.author","Cetindag, Arda C."],["dc.contributor.author","Dobisch, Laura"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Ertl-Wagner, Birgit B."],["dc.contributor.author","Goya-Maldonado, Roberto"],["dc.contributor.author","Fliessbach, Klaus"],["dc.contributor.author","Haynes, John D."],["dc.contributor.author","Heneka, Michael T."],["dc.contributor.author","Janowitz, Daniel"],["dc.contributor.author","Kilimann, Ingo"],["dc.contributor.author","Laske, Christoph"],["dc.contributor.author","Metzger, Coraline D."],["dc.contributor.author","Munk, Matthias H."],["dc.contributor.author","Peters, Oliver"],["dc.contributor.author","Priller, Josef"],["dc.contributor.author","Roy, Nina"],["dc.contributor.author","Scheffler, Klaus"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Spottke, Annika"],["dc.contributor.author","Spruth, Eike J."],["dc.contributor.author","Teipel, Stefan"],["dc.contributor.author","Tscheuschler, Maike"],["dc.contributor.author","Vukovich, Ruth"],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Duezel, Emrah"],["dc.contributor.author","Jessen, Frank"],["dc.date.accessioned","2021-06-01T09:42:25Z"],["dc.date.available","2021-06-01T09:42:25Z"],["dc.date.issued","2021"],["dc.date.updated","2022-02-09T13:21:10Z"],["dc.description.abstract","Background: The hippocampus and its subfields (HippSub) are reported to be diminished in patients with Alzheimer's disease (AD), bipolar disorder (BD), and major depressive disorder (MDD). We examined these groups vs healthy controls (HC) to reveal HippSub alterations between diseases. Methods: We segmented 3T-MRI T2-weighted hippocampal images of 67 HC, 58 BD, and MDD patients from the AFFDIS study and 137 patients from the DELCODE study assessing cognitive decline, including subjective cognitive decline (SCD), amnestic mild cognitive impairment (aMCI), and AD, via Free Surfer 6.0 to compare volumes across groups. Results: Groups differed significantly in several HippSub volumes, particularly between patients with AD and mood disorders. In comparison to HC, significant lower volumes appear in aMCI and AD groups in specific subfields. Smaller volumes in the left presubiculum are detected in aMCI and AD patients, differing from the BD group. A significant linear regression is seen between left hippocampus volume and duration since the first depressive episode. Conclusions: HippSub volume alterations were observed in AD, but not in early-onset MDD and BD, reinforcing the notion of different neural mechanisms in hippocampal degeneration. Moreover, duration since the first depressive episode was a relevant factor explaining the lower left hippocampal volumes present in groups."],["dc.identifier.doi","10.3389/fnagi.2021.626974"],["dc.identifier.eissn","1663-4365"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/85247"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.publisher","Frontiers Media S.A."],["dc.relation.eissn","1663-4365"],["dc.rights","http://creativecommons.org/licenses/by/4.0/"],["dc.rights.uri","http://creativecommons.org/licenses/by/4.0/"],["dc.title","Hippocampal and Hippocampal-Subfield Volumes From Early-Onset Major Depression and Bipolar Disorder to Cognitive Decline"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.journal","Journal of Neurochemistry"],["dc.bibliographiccitation.volume","138"],["dc.contributor.author","Straub, S."],["dc.contributor.author","Schroeter, M. L."],["dc.contributor.author","Diehl-Schmid, Janine"],["dc.contributor.author","Danek, A."],["dc.contributor.author","von Arnim, Christine A. F."],["dc.contributor.author","Bertram, L."],["dc.contributor.author","Einsiedler, B."],["dc.contributor.author","Fassbender, Klaus"],["dc.contributor.author","Feneberg, Emily"],["dc.contributor.author","Fliessbach, Klaus"],["dc.contributor.author","Foerstl, Hans"],["dc.contributor.author","Huppertz, H-J"],["dc.contributor.author","Jahn, Holger"],["dc.contributor.author","Jessen, Frank"],["dc.contributor.author","Kasper, E."],["dc.contributor.author","Kassubek, Jan"],["dc.contributor.author","Kestler, Hans A."],["dc.contributor.author","Kornhuber, Johannes"],["dc.contributor.author","Kubisch, C."],["dc.contributor.author","Landwehrmeyer, Bernhard"],["dc.contributor.author","Lauer, Martin"],["dc.contributor.author","Lausser, L."],["dc.contributor.author","Lill, C. M."],["dc.contributor.author","Ludolph, A."],["dc.contributor.author","Maler, M."],["dc.contributor.author","Muche, Rainer"],["dc.contributor.author","Pinkhardt, Elmar H."],["dc.contributor.author","Prudlo, Johannes"],["dc.contributor.author","Riedl, Lina"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Schomburg, R."],["dc.contributor.author","Teipel, Stefan J."],["dc.contributor.author","Uttner, Ingo"],["dc.contributor.author","Volk, Alexander E."],["dc.contributor.author","Otto, Markus"],["dc.date.accessioned","2018-11-07T10:10:49Z"],["dc.date.available","2018-11-07T10:10:49Z"],["dc.date.issued","2016"],["dc.format.extent","407"],["dc.identifier.isi","000382568400474"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/39933"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-blackwell"],["dc.publisher.place","Hoboken"],["dc.relation.conference","10th International Conference on Frontotemporal Dementias"],["dc.relation.eventlocation","Munich, GERMANY"],["dc.relation.issn","1471-4159"],["dc.relation.issn","0022-3042"],["dc.title","Multivariate diagnostic approaches in Frontotemporal lobar degeneration Data from the german FTLDc"],["dc.type","conference_abstract"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","7S_Part_23"],["dc.bibliographiccitation.journal","Alzheimer's & Dementia"],["dc.bibliographiccitation.volume","13"],["dc.contributor.author","Dyrba, Martin"],["dc.contributor.author","Metzger, Coraline D."],["dc.contributor.author","Grothe, Michel J."],["dc.contributor.author","Jessen, Frank"],["dc.contributor.author","Duzel, Emrah"],["dc.contributor.author","Spottke, Annika"],["dc.contributor.author","Nestor, Peter"],["dc.contributor.author","Buerger, Katharina"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Oliver, Peters"],["dc.contributor.author","Teipel, Stefan J."],["dc.contributor.authorgroup","DELCODE Consortium"],["dc.date.accessioned","2021-12-08T12:27:22Z"],["dc.date.available","2021-12-08T12:27:22Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1016/j.jalz.2017.06.1609"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/95329"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-476"],["dc.relation.eissn","1552-5279"],["dc.relation.issn","1552-5260"],["dc.rights.uri","http://onlinelibrary.wiley.com/termsAndConditions#vor"],["dc.title","[P3–393]: Robust Automated Detection of Subjective Cognitive Decline and Prodromal Alzheimer's Disease Based on Multicenter Resting‐State Functional Connectivity: Results from the Dzne Delcode Study"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","e206027"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","JAMA Network Open"],["dc.bibliographiccitation.volume","3"],["dc.contributor.author","Maier, Franziska"],["dc.contributor.author","Spottke, Annika"],["dc.contributor.author","Bach, Jan-Philipp"],["dc.contributor.author","Bartels, Claudia"],["dc.contributor.author","Buerger, Katharina"],["dc.contributor.author","Dodel, Richard"],["dc.contributor.author","Fellgiebel, Andreas"],["dc.contributor.author","Fliessbach, Klaus"],["dc.contributor.author","Frölich, Lutz"],["dc.contributor.author","Hausner, Lucrezia"],["dc.contributor.author","Hellmich, Martin"],["dc.contributor.author","Klöppel, Stefan"],["dc.contributor.author","Klostermann, Arne"],["dc.contributor.author","Kornhuber, Johannes"],["dc.contributor.author","Laske, Christoph"],["dc.contributor.author","Peters, Oliver"],["dc.contributor.author","Priller, Josef"],["dc.contributor.author","Richter-Schmidinger, Tanja"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Shah-Hosseini, Kija"],["dc.contributor.author","Teipel, Stefan"],["dc.contributor.author","von Arnim, Christine A. F."],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Jessen, Frank"],["dc.date.accessioned","2021-04-14T08:26:21Z"],["dc.date.available","2021-04-14T08:26:21Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1001/jamanetworkopen.2020.6027"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81913"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","2574-3805"],["dc.title","Bupropion for the Treatment of Apathy in Alzheimer Disease"],["dc.title.alternative","A Randomized Clinical Trial"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","455"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Alzheimer's Disease"],["dc.bibliographiccitation.lastpage","465"],["dc.bibliographiccitation.volume","72"],["dc.contributor.author","Teipel, Stefan J."],["dc.contributor.author","Kuper-Smith, Jan O."],["dc.contributor.author","Bartels, Claudia"],["dc.contributor.author","Brosseron, Frederic"],["dc.contributor.author","Buchmann, Martina"],["dc.contributor.author","Buerger, Katharina"],["dc.contributor.author","Catak, Cihan"],["dc.contributor.author","Janowitz, Daniel"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Dobisch, Laura"],["dc.contributor.author","Ertl-Wagner, Birgit"],["dc.contributor.author","Fließbach, Klaus"],["dc.contributor.author","Haynes, John-Dylan"],["dc.contributor.author","Heneka, Michael T."],["dc.contributor.author","Kilimann, Ingo"],["dc.contributor.author","Laske, Christoph"],["dc.contributor.author","Li, Siyao"],["dc.contributor.author","Menne, Felix"],["dc.contributor.author","Metzger, Coraline D."],["dc.contributor.author","Priller, Josef"],["dc.contributor.author","Pross, Verena"],["dc.contributor.author","Ramirez, Alfredo"],["dc.contributor.author","Scheffler, Klaus"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Spottke, Annika"],["dc.contributor.author","Spruth, Eike J."],["dc.contributor.author","Wagner, Michael"],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Wolfsgruber, Steffen"],["dc.contributor.author","Düzel, Emrah"],["dc.contributor.author","Jessen, Frank"],["dc.contributor.author","Dyrba, Martin"],["dc.contributor.editor","Zhou, Juan Helen"],["dc.date.accessioned","2020-12-10T18:44:13Z"],["dc.date.available","2020-12-10T18:44:13Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.3233/JAD-190446"],["dc.identifier.eissn","1875-8908"],["dc.identifier.issn","1387-2877"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/16953"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78366"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY-NC 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by-nc/4.0"],["dc.title","Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer’s Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","102495"],["dc.bibliographiccitation.journal","NeuroImage: Clinical"],["dc.bibliographiccitation.volume","28"],["dc.contributor.author","Herdick, Meret"],["dc.contributor.author","Dyrba, Martin"],["dc.contributor.author","Fritz, Hans-Christian J."],["dc.contributor.author","Altenstein, Slawek"],["dc.contributor.author","Ballarini, Tommaso"],["dc.contributor.author","Brosseron, Frederic"],["dc.contributor.author","Buerger, Katharina"],["dc.contributor.author","Can Cetindag, Arda"],["dc.contributor.author","Dechent, Peter"],["dc.contributor.author","Dobisch, Laura"],["dc.contributor.author","Duezel, Emrah"],["dc.contributor.author","Ertl-Wagner, Birgit"],["dc.contributor.author","Fliessbach, Klaus"],["dc.contributor.author","Dawn Freiesleben, Silka"],["dc.contributor.author","Frommann, Ingo"],["dc.contributor.author","Glanz, Wenzel"],["dc.contributor.author","Dylan Haynes, John"],["dc.contributor.author","Heneka, Michael T."],["dc.contributor.author","Janowitz, Daniel"],["dc.contributor.author","Kilimann, Ingo"],["dc.contributor.author","Laske, Christoph"],["dc.contributor.author","Metzger, Coraline D."],["dc.contributor.author","Munk, Matthias H."],["dc.contributor.author","Peters, Oliver"],["dc.contributor.author","Priller, Josef"],["dc.contributor.author","Roy, Nina"],["dc.contributor.author","Scheffler, Klaus"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Spottke, Annika"],["dc.contributor.author","Jakob Spruth, Eike"],["dc.contributor.author","Tscheuschler, Maike"],["dc.contributor.author","Vukovich, Ruth"],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Jessen, Frank"],["dc.contributor.author","Teipel, Stefan"],["dc.contributor.author","Grothe, Michel J."],["dc.date.accessioned","2021-04-14T08:27:38Z"],["dc.date.available","2021-04-14T08:27:38Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1016/j.nicl.2020.102495"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82356"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.issn","2213-1582"],["dc.title","Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer’s disease spectrum"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","361"],["dc.bibliographiccitation.issue","07/08"],["dc.bibliographiccitation.journal","Fortschritte der Neurologie · Psychiatrie"],["dc.bibliographiccitation.lastpage","367"],["dc.bibliographiccitation.volume","90"],["dc.contributor.author","Onur, Oezguer A."],["dc.contributor.author","Wolff-Menzler, Claus"],["dc.contributor.author","von Arnim, Christine A. F."],["dc.contributor.author","Jessen, Frank"],["dc.contributor.author","Fink, Gereon R."],["dc.contributor.author","Wiltfang, Jens"],["dc.contributor.author","Laske, Christoph"],["dc.contributor.author","Schneider, Anja"],["dc.contributor.author","Levin, Johannes"],["dc.contributor.author","Oberstein, Timo"],["dc.contributor.author","Frölich, Lutz"],["dc.date.accessioned","2022-09-01T09:50:17Z"],["dc.date.available","2022-09-01T09:50:17Z"],["dc.date.issued","2022"],["dc.description.abstract","Zusammenfassung\n Demenzen sind teure Erkrankungen: die jährlichen Kosten betragen in\n europäischen Versorgungssystemen etwa 28.000 €/Fall mit\n einer starken Stadien-Abhängigkeit, davon entfallen etwa 19% auf\n die medizinische Versorgung. Die diagnostischen Kosten hingegen verursachen\n davon nur einen geringen Teil. Mit Wandel des konzeptuellen\n Verständnisses von Demenzerkrankungen, der\n Behandlungsmöglichkeiten und der Leitlinien spielen zunehmend auch\n Biomarker-Untersuchungen eine wichtige Rolle. Die ökonomischen\n Auswirkungen der Biomarker-basierten Diagnostik sind derzeit nicht sicher\n abschätzbar. Zur Erhebung der Kosten einer leitlinien-orientierten\n ätiologischen Erst-Diagnostik von kognitiven Störungen wurde\n eine Umfrage im Deutschen Netzwerk Gedächtnisambulanzen (DNG)\n durchgeführt. An 15 Expertenzentren des DNG wurden systematisch die\n Personalbindungszeiten für alle Prozeduren und alle beteiligten\n Berufsgruppen erhoben und die Personalkosten basierend auf den\n tarifvertraglichen Arbeitgeberkosten berechnet. Zusammen mit den Kosten\n für technische Untersuchungen wurden Gesamtkosten der Diagnostik\n für drei Szenarien abgeschätzt: Diagnostik ohne Biomarker\n € 633,97 €, Diagnostik mit Liquoruntersuchungen\n € 1.214,90 und Diagnostik mit FDG- plus Amyloid-PET\n € 4.740,58. Zusätzlich erfolgte eine Analyse der\n derzeitigen realen Kostensituation in Gedächtnisambulanzen, wobei die\n Personalbindungszeiten für einzelne Leistungen und die apparativen\n Kosten ins Verhältnis zur Häufigkeit ihrer Anwendung gesetzt\n wurden. Als Mittelwert aller Zentren ergeben sich dabei Gesamtkosten von\n € 1.394,43/Fall (Mittelwert der Personalkosten\n € 351,72, Mittelwert der Kosten für apparative\n Diagnostik € 1.042,71). Die Ergebnisse zeigen, dass eine\n ätiologische Diagnostik von kognitiven Störungen (Demenzen und\n leichte kognitive Störung) einen Ressourceneinsatz erfordert, welcher\n derzeit weder durch die Vergütungssysteme von Ambulanzen noch durch die\n vertragsärztliche Vergütung kostendeckend erstattet wird. Die\n Biomarker-gestützte Diagnostik dementieller und prädementieller\n Syndrome wird häufiger werden, wenn sie zur Indikationsstellung vor\n einer krankheits-modifizierenden Therapie erforderlich ist. Deshalb\n müssen neue Finanzierungsmodelle entwickelt werden, um die\n gegenwärtige Lücke in der Kostenerstattung für die\n ätiologische Diagnostik kognitiver Störungen zu\n schließen."],["dc.identifier.doi","10.1055/a-1871-9889"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/113670"],["dc.language.iso","de"],["dc.notes.intern","DOI-Import GROB-597"],["dc.relation.eissn","1439-3522"],["dc.relation.issn","0720-4299"],["dc.title","Kosten der Diagnostik kognitiver Störungen in deutschen\n Gedächtnisambulanzen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]