Rosenberger, Albert

[["dc.bibliographiccitation.firstpage","937"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","International Archives of Occupational and Environmental Health"],["dc.bibliographiccitation.lastpage","950"],["dc.bibliographiccitation.volume","91"],["dc.contributor.author","Rosenberger, Albert"],["dc.contributor.author","Hung, Rayjean J."],["dc.contributor.author","Christiani, David C."],["dc.contributor.author","Caporaso, Neil E."],["dc.contributor.author","Liu, Geoffrey"],["dc.contributor.author","Bojesen, Stig E."],["dc.contributor.author","Le Marchand, Loic"],["dc.contributor.author","Haiman, Ch. A."],["dc.contributor.author","Albanes, Demetrios"],["dc.contributor.author","Aldrich, Melinda C."],["dc.contributor.author","Tardon, Adonina"],["dc.contributor.author","Fernández-Tardón, G."],["dc.contributor.author","Rennert, Gad"],["dc.contributor.author","Field, John K."],["dc.contributor.author","Kiemeney, B."],["dc.contributor.author","Lazarus, Philip"],["dc.contributor.author","Haugen, Aage"],["dc.contributor.author","Zienolddiny, Shanbeh"],["dc.contributor.author","Lam, Stephen"],["dc.contributor.author","Schabath, Matthew B."],["dc.contributor.author","Andrew, Angeline S."],["dc.contributor.author","Brunnsstöm, Hans"],["dc.contributor.author","Goodman, Gary E."],["dc.contributor.author","Doherty, Jennifer A."],["dc.contributor.author","Chen, Chu"],["dc.contributor.author","Teare, M. Dawn"],["dc.contributor.author","Wichmann, H.-Erich"],["dc.contributor.author","Manz, Judith"],["dc.contributor.author","Risch, Angela"],["dc.contributor.author","Muley, Thomas R."],["dc.contributor.author","Johansson, Mikael"],["dc.contributor.author","Brennan, Paul"],["dc.contributor.author","Landi, Maria Teresa"],["dc.contributor.author","Amos, Christopher I."],["dc.contributor.author","Pesch, Beate"],["dc.contributor.author","Johnen, Georg"],["dc.contributor.author","Brüning, Thomas"],["dc.contributor.author","Bickeböller, Heike"],["dc.contributor.author","Gomolka, Maria"],["dc.date.accessioned","2020-12-10T14:10:35Z"],["dc.date.available","2020-12-10T14:10:35Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1007/s00420-018-1334-3"],["dc.identifier.eissn","1432-1246"],["dc.identifier.issn","0340-0131"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/70809"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","935"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Cancer Epidemiology, Biomarkers & Prevention"],["dc.bibliographiccitation.lastpage","942"],["dc.bibliographiccitation.volume","28"],["dc.contributor.author","Zhu, Ying"],["dc.contributor.author","Wei, Yongyue"],["dc.contributor.author","Zhang, Ruyang"],["dc.contributor.author","Dong, Xuesi"],["dc.contributor.author","Shen, Sipeng"],["dc.contributor.author","Zhao, Yang"],["dc.contributor.author","Bai, Jianling"],["dc.contributor.author","Albanes, Demetrius"],["dc.contributor.author","Caporaso, Neil E."],["dc.contributor.author","Landi, Maria Teresa"],["dc.contributor.author","Zhu, Bin"],["dc.contributor.author","Chanock, Stephen J."],["dc.contributor.author","Gu, Fangyi"],["dc.contributor.author","Lam, Stephen"],["dc.contributor.author","Tsao, Ming-Sound"],["dc.contributor.author","Shepherd, Frances A."],["dc.contributor.author","Tardon, Adonina"],["dc.contributor.author","Fernández-Somoano, Ana"],["dc.contributor.author","Fernandez-Tardon, Guillermo"],["dc.contributor.author","Chen, Chu"],["dc.contributor.author","Barnett, Matthew J."],["dc.contributor.author","Doherty, Jennifer"],["dc.contributor.author","Bojesen, Stig E."],["dc.contributor.author","Johansson, Mattias"],["dc.contributor.author","Brennan, Paul"],["dc.contributor.author","McKay, James D."],["dc.contributor.author","Carreras-Torres, Robert"],["dc.contributor.author","Muley, Thomas"],["dc.contributor.author","Risch, Angela"],["dc.contributor.author","Wichmann, Heunz-Erich"],["dc.contributor.author","Bickeboeller, Heike"],["dc.contributor.author","Rosenberger, Albert"],["dc.contributor.author","Rennert, Gad"],["dc.contributor.author","Saliba, Walid"],["dc.contributor.author","Arnold, Susanne M."],["dc.contributor.author","Field, John K."],["dc.contributor.author","Davies, Michael P.A."],["dc.contributor.author","Marcus, Michael W."],["dc.contributor.author","Wu, Xifeng"],["dc.contributor.author","Ye, Yuanqing"],["dc.contributor.author","Le Marchand, Loic"],["dc.contributor.author","Wilkens, Lynne R."],["dc.contributor.author","Melander, Olle"],["dc.contributor.author","Manjer, Jonas"],["dc.contributor.author","Brunnström, Hans"],["dc.contributor.author","Hung, Rayjean J."],["dc.contributor.author","Liu, Geoffrey"],["dc.contributor.author","Brhane, Yonathan"],["dc.contributor.author","Kachuri, Linda"],["dc.contributor.author","Andrew, Angeline S."],["dc.contributor.author","Duell, Eric J."],["dc.contributor.author","Kiemeney, Lambertus A."],["dc.contributor.author","van der Heijden, Erik HFM"],["dc.contributor.author","Haugen, Aage"],["dc.contributor.author","Zienolddiny, Shanbeh"],["dc.contributor.author","Skaug, Vidar"],["dc.contributor.author","Grankvist, Kjell"],["dc.contributor.author","Johansson, Mikael"],["dc.contributor.author","Woll, Penella J."],["dc.contributor.author","Cox, Angela"],["dc.contributor.author","Taylor, Fiona"],["dc.contributor.author","Teare, Dawn M."],["dc.contributor.author","Lazarus, Philip"],["dc.contributor.author","Schabath, Matthew B."],["dc.contributor.author","Aldrich, Melinda C."],["dc.contributor.author","Houlston, Richard S."],["dc.contributor.author","McLaughlin, John"],["dc.contributor.author","Stevens, Victoria L."],["dc.contributor.author","Shen, Hongbing"],["dc.contributor.author","Hu, Zhibin"],["dc.contributor.author","Dai, Juncheng"],["dc.contributor.author","Amos, Christopher I."],["dc.contributor.author","Han, Younghun"],["dc.contributor.author","Zhu, Dakai"],["dc.contributor.author","Goodman, Gary E."],["dc.contributor.author","Chen, Feng"],["dc.contributor.author","Christiani, David C."],["dc.date.accessioned","2020-12-10T18:37:45Z"],["dc.date.available","2020-12-10T18:37:45Z"],["dc.date.issued","2019"],["dc.description.abstract","Platelets are a critical element in coagulation and inflammation, and activated platelets are linked to cancer risk through diverse mechanisms. However, a causal relationship between platelets and risk of lung cancer remains unclear."],["dc.identifier.doi","10.1158/1055-9965.EPI-18-0356"],["dc.identifier.eissn","1538-7755"],["dc.identifier.issn","1055-9965"],["dc.identifier.pmid","30700444"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77082"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.relation.eissn","1538-7755"],["dc.relation.issn","1055-9965"],["dc.relation.issn","1538-7755"],["dc.title","Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","219"],["dc.bibliographiccitation.journal","EBioMedicine"],["dc.bibliographiccitation.lastpage","226"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Chen, Li-Shiun"],["dc.contributor.author","Baker, Timothy"],["dc.contributor.author","Hung, Rayjean J."],["dc.contributor.author","Horton, Amy"],["dc.contributor.author","Culverhouse, Robert"],["dc.contributor.author","Hartz, Sarah"],["dc.contributor.author","Saccone, Nancy"],["dc.contributor.author","Cheng, Iona"],["dc.contributor.author","Deng, Bo"],["dc.contributor.author","Han, Younghun"],["dc.contributor.author","Hansen, Helen M."],["dc.contributor.author","Horsman, Janet"],["dc.contributor.author","Kim, Claire"],["dc.contributor.author","Rosenberger, Albert"],["dc.contributor.author","Aben, Katja K."],["dc.contributor.author","Andrew, Angeline S."],["dc.contributor.author","Chang, Shen-Chih"],["dc.contributor.author","Saum, Kai-Uwe"],["dc.contributor.author","Dienemann, Hendrik"],["dc.contributor.author","Hatsukami, Dorothy K."],["dc.contributor.author","Johnson, Eric O."],["dc.contributor.author","Pande, Mala"],["dc.contributor.author","Wrensch, Margaret R."],["dc.contributor.author","McLaughlin, John"],["dc.contributor.author","Skaug, Vidar"],["dc.contributor.author","van der Heijden, Erik H."],["dc.contributor.author","Wampfler, Jason"],["dc.contributor.author","Wenzlaff, Angela"],["dc.contributor.author","Woll, Penella"],["dc.contributor.author","Zienolddiny, Shanbeh"],["dc.contributor.author","Bickeböller, Heike"],["dc.contributor.author","Brenner, Hermann"],["dc.contributor.author","Duell, Eric J."],["dc.contributor.author","Haugen, Aage"],["dc.contributor.author","Brüske, Irene"],["dc.contributor.author","Kiemeney, Lambertus A."],["dc.contributor.author","Lazarus, Philip"],["dc.contributor.author","Le Marchand, Loic"],["dc.contributor.author","Liu, Geoffrey"],["dc.contributor.author","Mayordomo, Jose"],["dc.contributor.author","Risch, Angela"],["dc.contributor.author","Schwartz, Ann G."],["dc.contributor.author","Teare, M. Dawn"],["dc.contributor.author","Wu, Xifeng"],["dc.contributor.author","Wiencke, John K."],["dc.contributor.author","Yang, Ping"],["dc.contributor.author","Zhang, Zuo-Feng"],["dc.contributor.author","Spitz, Margaret R."],["dc.contributor.author","Amos, Christopher I."],["dc.contributor.author","Bierut, Laura J."],["dc.date.accessioned","2020-12-10T14:23:30Z"],["dc.date.available","2020-12-10T14:23:30Z"],["dc.date.issued","2016"],["dc.identifier.doi","10.1016/j.ebiom.2016.08.012"],["dc.identifier.issn","2352-3964"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/71947"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes — A Meta-Analysis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","587"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Carcinogenesis"],["dc.bibliographiccitation.lastpage","597"],["dc.bibliographiccitation.volume","33"],["dc.contributor.author","Rosenberger, Albert"],["dc.contributor.author","Bickeboeller, Heike"],["dc.contributor.author","McCormack, Valerie"],["dc.contributor.author","Brenner, Darren R."],["dc.contributor.author","Duell, Eric J."],["dc.contributor.author","Tjonneland, Anne"],["dc.contributor.author","Friis, Soren"],["dc.contributor.author","Muscat, Joshua E."],["dc.contributor.author","Yang, Ping"],["dc.contributor.author","Wichmann, H-Erich"],["dc.contributor.author","Heinrich, Joachim"],["dc.contributor.author","Szeszenia-Dabrowska, Neonila"],["dc.contributor.author","Lissowska, Jolanta"],["dc.contributor.author","Zaridze, David"],["dc.contributor.author","Rudnai, Peter"],["dc.contributor.author","Fabianova, Eleonora"],["dc.contributor.author","Janout, Vladimir"],["dc.contributor.author","Bencko, Vladimir"],["dc.contributor.author","Brennan, P. C."],["dc.contributor.author","Mates, Dana"],["dc.contributor.author","Schwartz, Ann G."],["dc.contributor.author","Cote, Michele L."],["dc.contributor.author","Zhang, Z."],["dc.contributor.author","Morgenstern, Hal"],["dc.contributor.author","Oh, Sam S."],["dc.contributor.author","Field, John K."],["dc.contributor.author","Raji, Olaide Y."],["dc.contributor.author","McLaughlin, John R."],["dc.contributor.author","Wiencke, John K."],["dc.contributor.author","LeMarchand, Loic"],["dc.contributor.author","Neri, Monica"],["dc.contributor.author","Bonassi, Stefano"],["dc.contributor.author","Andrew, Angeline S."],["dc.contributor.author","Lan, Qing"],["dc.contributor.author","Hu, Wei"],["dc.contributor.author","Orlow, Irene"],["dc.contributor.author","Park, Bernard J."],["dc.contributor.author","Boffetta, Paolo"],["dc.contributor.author","Hung, Rayjean J."],["dc.date.accessioned","2018-11-07T09:13:01Z"],["dc.date.available","2018-11-07T09:13:01Z"],["dc.date.issued","2012"],["dc.description.abstract","Asthma has been hypothesized to be associated with lung cancer (LC) risk. We conducted a pooled analysis of 16 studies in the International Lung Cancer Consortium (ILCCO) to quantitatively assess this association and compared the results with 36 previously published studies. In total, information from 585 444 individuals was used. Study-specific measures were combined using random effects models. A meta-regression and subgroup meta-analyses were performed to identify sources of heterogeneity. The overall LC relative risk (RR) associated with asthma was 1.28 [95% confidence intervals (CIs) = 1.16-1.41] but with large heterogeneity (I-2 = 73%, P < 0.001) between studies. Among ILCCO studies, an increased risk was found for squamous cell (RR = 1.69, 95%, CI = 1.26-2.26) and for small-cell carcinoma (RR = 1.71, 95% CI = 0.99-2.95) but was weaker for adenocarcinoma (RR = 1.09, 95% CI = 0.88-1.36). The increased LC risk was strongest in the 2 years after asthma diagnosis (RR = 2.13, 95% CI = 1.09-4.17) but subjects diagnosed with asthma over 10 years prior had no or little increased LC risk (RR = 1.10, 95% CI = 0.94-1.30). Because the increased incidence of LC was chiefly observed in small cell and squamous cell lung carcinomas, primarily within 2 years of asthma diagnosis and because the association was weak among never smokers, we conclude that the association may not reflect a causal effect of asthma on the risk of LC."],["dc.identifier.doi","10.1093/carcin/bgr307"],["dc.identifier.isi","000300988100014"],["dc.identifier.pmid","22198214"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27075"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press"],["dc.relation.issn","1460-2180"],["dc.relation.issn","0143-3334"],["dc.title","Asthma and lung cancer risk: a systematic investigation by the International Lung Cancer Consortium"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","djv100"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","JNCI Journal of the National Cancer Institute"],["dc.bibliographiccitation.volume","107"],["dc.contributor.author","Chen, Li-Shiun"],["dc.contributor.author","Hung, Rayjean J."],["dc.contributor.author","Baker, Timothy"],["dc.contributor.author","Horton, Amy"],["dc.contributor.author","Culverhouse, Rob"],["dc.contributor.author","Saccone, Nancy"],["dc.contributor.author","Cheng, Iona"],["dc.contributor.author","Deng, B. O."],["dc.contributor.author","Han, Younghun"],["dc.contributor.author","Hansen, Helen M."],["dc.contributor.author","Horsman, Janet"],["dc.contributor.author","Kim, Claire"],["dc.contributor.author","Lutz, Sharon"],["dc.contributor.author","Rosenberger, Albert"],["dc.contributor.author","Aben, Katja K."],["dc.contributor.author","Andrew, Angeline S."],["dc.contributor.author","Breslau, Naomi"],["dc.contributor.author","Chang, Shen-Chih"],["dc.contributor.author","Dieffenbach, Aida Karina"],["dc.contributor.author","Dienemann, Hendrik"],["dc.contributor.author","Frederiksen, Brittni"],["dc.contributor.author","Han, Jiali"],["dc.contributor.author","Hatsukami, Dorothy K."],["dc.contributor.author","Johnson, Eric O."],["dc.contributor.author","Pande, Mala"],["dc.contributor.author","Wrensch, Margaret R."],["dc.contributor.author","McLaughlin, John R."],["dc.contributor.author","Skaug, Vidar"],["dc.contributor.author","van der Heijden, Henricus F. M."],["dc.contributor.author","Wampfler, Jason"],["dc.contributor.author","Wenzlaff, Angela"],["dc.contributor.author","Woll, Penella J."],["dc.contributor.author","Zienolddiny, Shanbeh"],["dc.contributor.author","Bickeboeller, Heike"],["dc.contributor.author","Brenner, Hermann"],["dc.contributor.author","Duell, Eric J."],["dc.contributor.author","Haugen, Aage"],["dc.contributor.author","Heinrich, Joachim"],["dc.contributor.author","Hokanson, John E."],["dc.contributor.author","Hunter, David J."],["dc.contributor.author","Kiemeney, Lambertus A."],["dc.contributor.author","Lazarus, Philip"],["dc.contributor.author","Le Marchand, Loic"],["dc.contributor.author","Liu, Geoffrey"],["dc.contributor.author","Mayordomo, Jose I."],["dc.contributor.author","Risch, Angela"],["dc.contributor.author","Schwartz, Ann G."],["dc.contributor.author","Teare, Dawn"],["dc.contributor.author","Wu, X."],["dc.contributor.author","Wiencke, John K."],["dc.contributor.author","Yang, Ping"],["dc.contributor.author","Zhang, Z."],["dc.contributor.author","Spitz, Margaret R."],["dc.contributor.author","Kraft, Peter"],["dc.contributor.author","Amos, Christopher I."],["dc.contributor.author","Bierut, Laura J."],["dc.date.accessioned","2018-11-07T09:57:38Z"],["dc.date.available","2018-11-07T09:57:38Z"],["dc.date.issued","2015"],["dc.description.abstract","Background: Recent meta-analyses show strong evidence of associations among genetic variants in CHRNA5 on chromosome 15q25, smoking quantity, and lung cancer. This meta-analysis tests whether the CHRNA5 variant rs16969968 predicts age of smoking cessation and age of lung cancer diagnosis. Methods: Meta-analyses examined associations between rs16969968, age of quitting smoking, and age of lung cancer diagnosis in 24 studies of European ancestry (n = 29 072). In each dataset, we used Cox regression models to evaluate the association between rs16969968 and the two primary phenotypes (age of smoking cessation among ever smokers and age of lung cancer diagnosis among lung cancer case patients) and the secondary phenotype of smoking duration. Heterogeneity across studies was assessed with the Cochran Q test. All statistical tests were two-sided. Results: The rs16969968 allele (A) was associated with a lower likelihood of smoking cessation (hazard ratio [HR] = 0.95, 95% confidence interval [CI] = 0.91 to 0.98, P =.0042), and the AA genotype was associated with a four-year delay in median age of quitting compared with the GG genotype. Among smokers with lung cancer diagnoses, the rs16969968 genotype (AA) was associated with a four-year earlier median age of diagnosis compared with the low-risk genotype (GG) (HR = 1.08, 95% CI = 1.04 to 1.12, P = 1.1 10(-5)). Conclusion: These data support the clinical significance of the CHRNA5 variant rs16969968. It predicts delayed smoking cessation and an earlier age of lung cancer diagnosis in this meta-analysis. Given the existing evidence that this CHRNA5 variant predicts favorable response to cessation pharmacotherapy, these findings underscore the potential clinical and public health importance of rs16969968 in CHRNA5 in relation to smoking cessation success and lung cancer risk.d: Recent meta-analyses show strong evidence of associations among genetic variants in CHRNA5 on chromosome 15q25, smoking quantity, and lung cancer. This meta-analysis tests whether the CHRNA5 variant rs16969968 predicts age of smoking cessation and age of lung cancer diagnosis."],["dc.identifier.doi","10.1093/jnci/djv100"],["dc.identifier.isi","000355088600029"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/37206"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.relation.issn","1460-2105"],["dc.relation.issn","0027-8874"],["dc.title","CHRNA5 Risk Variant Predicts Delayed Smoking Cessation and Earlier Lung Cancer Diagnosis-A Meta-Analysis"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","573"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","American Journal of Epidemiology"],["dc.bibliographiccitation.lastpage","585"],["dc.bibliographiccitation.volume","176"],["dc.contributor.author","Brenner, Darren R."],["dc.contributor.author","Boffetta, Paolo"],["dc.contributor.author","Duell, Eric J."],["dc.contributor.author","Bickeboeller, Heike"],["dc.contributor.author","Rosenberger, Albert"],["dc.contributor.author","McCormack, Valerie"],["dc.contributor.author","Muscat, Joshua E."],["dc.contributor.author","Yang, Ping"],["dc.contributor.author","Wichmann, Heinz-Erich"],["dc.contributor.author","Brueske-Hohlfeld, Irene"],["dc.contributor.author","Schwartz, Ann G."],["dc.contributor.author","Cote, Michele L."],["dc.contributor.author","Tjonneland, Anne"],["dc.contributor.author","Friis, Soren"],["dc.contributor.author","Le Marchand, Loic"],["dc.contributor.author","Zhang, Z."],["dc.contributor.author","Morgenstern, Hal"],["dc.contributor.author","Szeszenia-Dabrowska, Neonila"],["dc.contributor.author","Lissowska, Jolanta"],["dc.contributor.author","Zaridze, David"],["dc.contributor.author","Rudnai, Peter"],["dc.contributor.author","Fabianova, Eleonora"],["dc.contributor.author","Foretova, Lenka"],["dc.contributor.author","Janout, Vladimir"],["dc.contributor.author","Bencko, Vladimir"],["dc.contributor.author","Schejbalova, Miriam"],["dc.contributor.author","Brennan, P. C."],["dc.contributor.author","Mates, Ioan N."],["dc.contributor.author","Lazarus, Philip"],["dc.contributor.author","Field, John K."],["dc.contributor.author","Raji, Olaide Y."],["dc.contributor.author","McLaughlin, John R."],["dc.contributor.author","Liu, Geoffrey"],["dc.contributor.author","Wiencke, John K."],["dc.contributor.author","Neri, Monica"],["dc.contributor.author","Ugolini, Donatella"],["dc.contributor.author","Andrew, Angeline S."],["dc.contributor.author","Lan, Qing"],["dc.contributor.author","Hu, Wei"],["dc.contributor.author","Orlow, Irene"],["dc.contributor.author","Park, Bernard J."],["dc.contributor.author","Hung, Rayjean J."],["dc.date.accessioned","2018-11-07T09:05:13Z"],["dc.date.available","2018-11-07T09:05:13Z"],["dc.date.issued","2012"],["dc.description.abstract","To clarify the role of previous lung diseases (chronic bronchitis, emphysema, pneumonia, and tuberculosis) in the development of lung cancer, the authors conducted a pooled analysis of studies in the International Lung Cancer Consortium. Seventeen studies including 24,607 cases and 81,829 controls (noncases), mainly conducted in Europe and North America, were included (19842011). Using self-reported data on previous diagnoses of lung diseases, the authors derived study-specific effect estimates by means of logistic regression models or Cox proportional hazards models adjusted for age, sex, and cumulative tobacco smoking. Estimates were pooled using random-effects models. Analyses stratified by smoking status and histology were also conducted. A history of emphysema conferred a 2.44-fold increased risk of lung cancer (95 confidence interval (CI): 1.64, 3.62 (16 studies)). A history of chronic bronchitis conferred a relative risk of 1.47 (95 CI: 1.29, 1.68 (13 studies)). Tuberculosis (relative risk 1.48, 95 CI: 1.17, 1.87 (16 studies)) and pneumonia (relative risk 1.57, 95 CI: 1.22, 2.01 (12 studies)) were also associated with lung cancer risk. Among never smokers, elevated risks were observed for emphysema, pneumonia, and tuberculosis. These results suggest that previous lung diseases influence lung cancer risk independently of tobacco use and that these diseases are important for assessing individual risk."],["dc.identifier.doi","10.1093/aje/kws151"],["dc.identifier.isi","000309411400002"],["dc.identifier.pmid","22986146"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/25267"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Oxford Univ Press Inc"],["dc.relation.issn","1476-6256"],["dc.relation.issn","0002-9262"],["dc.title","Previous Lung Diseases and Lung Cancer Risk: A Pooled Analysis From the International Lung Cancer Consortium"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]