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Notch Signaling: Numb Makes the Difference
ISSN
0960-9822
Date Issued
2012
Author(s)
Giebel, Bernd
DOI
10.1016/j.cub.2012.01.006
Abstract
During Drosophila sensory organ precursor cell development, Numb segregates asymmetrically and functions as a cell fate determinant. Recent work now demonstrates in vivo that Numb inactivates Notch by promoting its endocytosis.