Wodarz, Andreas

[["dc.bibliographiccitation.firstpage","bio046789"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Biology Open"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Tiwari, Manu D."],["dc.contributor.author","Zeitler, Daniela M."],["dc.contributor.author","Meister, Gunter"],["dc.contributor.author","Wodarz, Andreas"],["dc.date.accessioned","2020-12-10T18:41:50Z"],["dc.date.available","2020-12-10T18:41:50Z"],["dc.date.issued","2019"],["dc.identifier.doi","10.1242/bio.046789"],["dc.identifier.eissn","2046-6390"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/17102"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/77698"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.notes.intern","Merged from goescholar"],["dc.rights","CC BY 4.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/4.0"],["dc.title","Molecular profiling of stem cell-like female germ line cells in Drosophila delineates networks important for stemness and differentiation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","3805"],["dc.bibliographiccitation.issue","19"],["dc.bibliographiccitation.journal","Development"],["dc.bibliographiccitation.lastpage","3815"],["dc.bibliographiccitation.volume","133"],["dc.contributor.author","Schneider, M."],["dc.contributor.author","Khalil, Ashraf A."],["dc.contributor.author","Poulton, J."],["dc.contributor.author","Castillejo-Lopez, C."],["dc.contributor.author","Egger-Adam, D."],["dc.contributor.author","Wodarz, A."],["dc.contributor.author","Deng, W. M."],["dc.contributor.author","Baumgartner, S."],["dc.date.accessioned","2019-07-10T08:12:42Z"],["dc.date.available","2019-07-10T08:12:42Z"],["dc.date.issued","2006"],["dc.identifier.fs","52673"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/3361"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/61008"],["dc.language.iso","en"],["dc.notes.intern","Merged from goescholar"],["dc.relation.orgunit","Göttinger Zentrum für Molekulare Biowissenschaften"],["dc.relation.orgunit","Universitätsmedizin Göttingen"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject.ddc","573"],["dc.subject.ddc","573.8"],["dc.subject.ddc","612"],["dc.subject.ddc","612.8"],["dc.subject.ddc","572.8"],["dc.title","Perlecan and Dystroglycan act at the basal side of the Drosophila follicular epithelium to maintain epithelial organization."],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","dev185421"],["dc.bibliographiccitation.issue","15"],["dc.bibliographiccitation.journal","Development"],["dc.bibliographiccitation.volume","147"],["dc.contributor.author","Linnemannstöns, Karen"],["dc.contributor.author","Witte, Leonie"],["dc.contributor.author","Karuna M, Pradhipa"],["dc.contributor.author","Kittel, Jeanette Clarissa"],["dc.contributor.author","Danieli, Adi"],["dc.contributor.author","Müller, Denise"],["dc.contributor.author","Nitsch, Lena"],["dc.contributor.author","Honemann-Capito, Mona"],["dc.contributor.author","Grawe, Ferdinand"],["dc.contributor.author","Wodarz, Andreas"],["dc.contributor.author","Gross, Julia Christina"],["dc.date.accessioned","2021-04-14T08:23:55Z"],["dc.date.available","2021-04-14T08:23:55Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1242/dev.185421"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/81097"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","1477-9129"],["dc.relation.issn","0950-1991"],["dc.title","Ykt6-dependent endosomal recycling is required for Wnt secretion in the Drosophila wing epithelium"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","R91"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Current Biology"],["dc.bibliographiccitation.lastpage","R92"],["dc.bibliographiccitation.volume","16"],["dc.contributor.author","Giebel, B."],["dc.contributor.author","Wodarz, Andreas"],["dc.date.accessioned","2018-11-07T10:18:45Z"],["dc.date.available","2018-11-07T10:18:45Z"],["dc.date.issued","2006"],["dc.description.abstract","Genetic defects of the endosomal 'ESCRT' machinery in Drosophila have been found to cause loss of epithelial cell polarity, accompanied by overproliferation of mutant and adjacent wild-type cells. These results can be attributed to defective endocytosis of transmembrane proteins that control cell polarity and proliferation, including Crumbs and Notch."],["dc.identifier.doi","10.1016/j.cub.2006.01.022"],["dc.identifier.isi","000235347400016"],["dc.identifier.pmid","16461271"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41513"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cell Press"],["dc.relation.issn","0960-9822"],["dc.title","Tumor suppressors: Control of signaling by endocytosis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1361"],["dc.bibliographiccitation.journal","Journal of Cell Biology"],["dc.bibliographiccitation.lastpage","1374"],["dc.bibliographiccitation.volume","150"],["dc.contributor.author","Wodarz, A."],["dc.contributor.author","Ramrath, A."],["dc.contributor.author","Grimm, A."],["dc.contributor.author","Knust, E."],["dc.date.accessioned","2019-07-10T08:12:42Z"],["dc.date.available","2019-07-10T08:12:42Z"],["dc.date.issued","2000"],["dc.format.mimetype","application/pdf"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?goescholar/3364"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/61011"],["dc.language.iso","en"],["dc.notes.intern","Migrated from goescholar"],["dc.rights","Goescholar"],["dc.rights.access","openAccess"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.subject","cell polarity; atypical PKC; Bazooka; tight junction; asymmetric cell division"],["dc.subject.ddc","573"],["dc.subject.ddc","573.8"],["dc.subject.ddc","612"],["dc.subject.ddc","612.8"],["dc.subject.ddc","572.8"],["dc.title","Drosophila Atypical Protein Kinase C Associates with Bazooka and Controls Polarity of Epithelia and Neuroblasts"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1016"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Nature Cell Biology"],["dc.bibliographiccitation.lastpage","1024"],["dc.bibliographiccitation.volume","9"],["dc.contributor.author","Wodarz, Andreas"],["dc.contributor.author","Naethke, Inke"],["dc.date.accessioned","2018-11-07T10:59:16Z"],["dc.date.available","2018-11-07T10:59:16Z"],["dc.date.issued","2007"],["dc.description.abstract","The development of cancer is a multistep process in which the DNA of a single cell accumulates mutations in genes that control essential cellular processes. Loss of cell-cell adhesion and cell polarity is commonly observed in advanced tumours and correlates well with their invasion into adjacent tissues and the formation of metastases. Growing evidence indicates that loss of cell-cell adhesion and cell polarity may also be important in early stages of cancer. The strongest hints in this direction come from studies on tumour suppressor genes in the fruitfly Drosophila melanogaster, which have revealed their importance in the control of apical-basal cell polarity."],["dc.identifier.doi","10.1038/ncb433"],["dc.identifier.isi","000249256500007"],["dc.identifier.pmid","17762893"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50658"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Nature Publishing Group"],["dc.relation.issn","1465-7392"],["dc.title","Cell polarity in development and cancer"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","71"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","The Journal of Cell Biology"],["dc.bibliographiccitation.lastpage","80"],["dc.bibliographiccitation.volume","193"],["dc.contributor.author","Morawe, Tobias"],["dc.contributor.author","Honemann-Capito, Mona"],["dc.contributor.author","von Stein, Walter"],["dc.contributor.author","Wodarz, Andreas"],["dc.date.accessioned","2018-11-07T08:57:07Z"],["dc.date.available","2018-11-07T08:57:07Z"],["dc.date.issued","2011"],["dc.description.abstract","In Drosophila melanogaster oogenesis, there are 16 germline cells that form a cyst and stay connected to each other by ring canals. Ring canals allow the cytoplasmic transport of proteins, messenger ribonucleic acids, and yolk components from the nurse cells into the oocyte. In this paper, we describe the protein Rings lost (Rngo) and show that it is required for ring canal growth in germline cysts. rngo is an essential gene, and germline clones of a rngo-null allele show defects in ovary development, including mislocalization of ring canal proteins and fusion of germline cells. Rngo appears to be a ubiquitin receptor that possesses a ubiquitin-like domain, a ubiquitin-associated domain, and a retroviral-like aspartate protease (RVP) domain. Rngo binds to ubiquitin and to the 26S proteasome and colocalizes with both in germline cells, and its RVP domain is required for dimerization of Rngo and for its function in vivo. Our results thus show, for the first time, a function for a ubiquitin receptor in Drosophila development."],["dc.identifier.doi","10.1083/jcb.201009142"],["dc.identifier.isi","000289077100010"],["dc.identifier.pmid","21444692"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/7828"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/23315"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Rockefeller Univ Press"],["dc.relation.issn","1540-8140"],["dc.relation.issn","0021-9525"],["dc.rights","Goescholar"],["dc.rights.uri","https://goescholar.uni-goettingen.de/licenses"],["dc.title","Loss of the extraproteasomal ubiquitin receptor Rings lost impairs ring canal growth in Drosophila oogenesis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1079"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Journal of Cell Biology"],["dc.bibliographiccitation.lastpage","1095"],["dc.bibliographiccitation.volume","217"],["dc.contributor.author","Beati, Hamze"],["dc.contributor.author","Peek, Irina"],["dc.contributor.author","Hordowska, Paulina"],["dc.contributor.author","Honemann-Capito, Mona"],["dc.contributor.author","Glashauser, Jade"],["dc.contributor.author","Renschler, Fabian A."],["dc.contributor.author","Kakanj, Parisa"],["dc.contributor.author","Ramrath, Andreas"],["dc.contributor.author","Leptin, Maria"],["dc.contributor.author","Luschnig, Stefan"],["dc.contributor.author","Wiesner, Silke"],["dc.contributor.author","Wodarz, Andreas"],["dc.date.accessioned","2020-12-10T18:15:35Z"],["dc.date.available","2020-12-10T18:15:35Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1083/jcb.201610098"],["dc.identifier.eissn","1540-8140"],["dc.identifier.issn","0021-9525"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/74893"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","The adherens junction–associated LIM domain protein Smallish regulates epithelial morphogenesis"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","636"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","Current Biology"],["dc.bibliographiccitation.lastpage","642"],["dc.bibliographiccitation.volume","20"],["dc.contributor.author","Krahn, Michael P."],["dc.contributor.author","Klopfenstein, Dieter Robert"],["dc.contributor.author","Fischer, Nannette"],["dc.contributor.author","Wodarz, Andreas"],["dc.date.accessioned","2018-11-07T08:44:08Z"],["dc.date.available","2018-11-07T08:44:08Z"],["dc.date.issued","2010"],["dc.description.abstract","Cell polarity in higher animals is controlled by evolutionarily conserved protein complexes, which localize to the cytocortex in a polarized manner [1, 2]. The PAR-3/PAR-6/atypical protein kinase C (aPKC) complex is the first to become asymmetrically localized, and it controls the localization of additional complexes functioning further downstream in the regulation of cell polarity [3-9]. The first component of the PAR-3/PAR-6/aPKC complex that is localized to the cortex is Bazooka/PAR-3 (Baz), a large scaffolding protein [10]. In most cell types analyzed, loss of Baz function leads to loss of cell polarity [6, 8, 11]. Here we present a structure-function analysis of Baz focusing on its subcellular localization and function in four different polarized Drosophila cell types: the embryonic ectodermal epidermis, the follicular epithelium, embryonic neuroblasts, and the oocyte. We show that the PDZ domains of Baz are dispensable for its correct localization, whereas a conserved region in the C-terminal part of Baz to which no function had been assigned so far is required and sufficient for membrane localization. This region binds to phosphoinositide membrane lipids and thus mediates cortical localization of Baz by direct interaction with the plasma membrane. Our findings reveal a mechanism for the coupling of plasma membrane polarity and cortical polarity."],["dc.identifier.doi","10.1016/j.cub.2010.01.065"],["dc.identifier.isi","000276753100028"],["dc.identifier.pmid","20303268"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/20129"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Cell Press"],["dc.relation.issn","0960-9822"],["dc.title","Membrane Targeting of Bazooka/PAR-3 Is Mediated by Direct Binding to Phosphoinositide Lipids"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","e60596"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","PLoS ONE"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Zhang, G."],["dc.contributor.author","Beati, Hamze"],["dc.contributor.author","Nilsson, Jakob"],["dc.contributor.author","Wodarz, Andreas"],["dc.date.accessioned","2018-11-07T09:26:08Z"],["dc.date.available","2018-11-07T09:26:08Z"],["dc.date.issued","2013"],["dc.description.abstract","Correct segregation of genetic material relies on proper assembly and maintenance of the mitotic spindle. How the highly dynamic microtubules (MTs) are maintained in stable mitotic spindles is a key question to be answered. Motor and non-motor microtubule associated proteins (MAPs) have been reported to stabilize the dynamic spindle through crosslinking adjacent MTs. Mars, a novel MAP, is essential for the early development of Drosophila embryos. Previous studies showed that Mars is required for maintaining an intact mitotic spindle but did not provide a molecular mechanism for this function. Here we show that Mars is able to stabilize the mitotic spindle in vivo. Both in vivo and in vitro data reveal that the N-terminal region of Mars functions in the stabilization of the mitotic spindle by crosslinking adjacent MTs."],["dc.description.sponsorship","Open-Access-Publikationsfonds 2013"],["dc.identifier.doi","10.1371/journal.pone.0060596"],["dc.identifier.isi","000319108100057"],["dc.identifier.pmid","23593258"],["dc.identifier.purl","https://resolver.sub.uni-goettingen.de/purl?gs-1/9128"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/30226"],["dc.notes.intern","Merged from goescholar"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Public Library Science"],["dc.relation.issn","1932-6203"],["dc.rights","CC BY 3.0"],["dc.rights.uri","https://creativecommons.org/licenses/by/3.0"],["dc.title","The Drosophila Microtubule-Associated Protein Mars Stabilizes Mitotic Spindles by Crosslinking Microtubules through Its N-Terminal Region"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.version","published_version"],["dspace.entity.type","Publication"]]