Options
Resilience in Lower Grade Glioma Patients
Date Issued
2022-11-02
Author(s)
Fröhlich, Ellen
Sassenrath, Claudia
Nadji-Ohl, Minou
Unteroberdörster, Meike
Rückriegel, Stefan
Roder, Constantin
Forster, Marie-Therese
Schommer, Stephan
Löhr, Mario
Pala, Andrej
Goebel, Simone
Gerlach, Rüdiger
Renovanz, Mirjam
Wirtz, Christian Rainer
Onken, Julia
Czabanka, Marcus
Tatagiba, Marcos Soares
Ernestus, Ralf-Ingo
Vajkoczy, Peter
Gansland, Oliver
Coburger, Jan
DOI
10.3390/cancers14215410
Abstract
Simple Summary
Current data show that resilience is an important factor in cancer patients’ well-being. We explored the resilience of patients with lower grade glioma (LGG) and the potentially influencing factors. Our data indicate that stigmatization and the functional status are significantly associated with the patients’ resilience. These factors should be identified and targeted therapeutically in clinical routines.
Abstract
Current data show that resilience is an important factor in cancer patients’ well-being. We aim to explore the resilience of patients with lower grade glioma (LGG) and the potentially influencing factors. We performed a cross-sectional assessment of adult patients with LGG who were enrolled in the LoG-Glio registry. By phone interview, we administered the following measures: Resilience Scale (RS-13), distress thermometer, Montreal Cognitive Assessment Test for visually impaired patients (MoCA-Blind), internalized stigmatization by brain tumor (ISBI), Eastern Cooperative Oncological Group performance status (ECOG), patients’ perspective questionnaire (PPQ) and typical clinical parameters. We calculated correlations and multivariate regression models. Of 74 patients who were assessed, 38% of those showed a low level of resilience. Our results revealed significant correlations of resilience with distress (p < 0.001, −0.49), MOCA (p = 0.003, 0.342), ECOG (p < 0.001, −0.602), stigmatization (p < 0.001, −0.558), pain (p < 0.001, −0.524), and occupation (p = 0.007, 0.329). In multivariate analyses, resilience was negatively associated with elevated ECOG (p = 0.020, β = −0.383) and stigmatization levels (p = 0.008, β = −0.350). Occupation showed a tendency towards a significant association with resilience (p = 0.088, β = −0.254). Overall, low resilience affected more than one third of our cohort. Low functional status is a specific risk factor for low resilience. The relevant influence of stigmatization on resilience is a novel finding for patients suffering from a glioma and should be routinely identified and targeted in clinical routine.
Current data show that resilience is an important factor in cancer patients’ well-being. We explored the resilience of patients with lower grade glioma (LGG) and the potentially influencing factors. Our data indicate that stigmatization and the functional status are significantly associated with the patients’ resilience. These factors should be identified and targeted therapeutically in clinical routines.
Abstract
Current data show that resilience is an important factor in cancer patients’ well-being. We aim to explore the resilience of patients with lower grade glioma (LGG) and the potentially influencing factors. We performed a cross-sectional assessment of adult patients with LGG who were enrolled in the LoG-Glio registry. By phone interview, we administered the following measures: Resilience Scale (RS-13), distress thermometer, Montreal Cognitive Assessment Test for visually impaired patients (MoCA-Blind), internalized stigmatization by brain tumor (ISBI), Eastern Cooperative Oncological Group performance status (ECOG), patients’ perspective questionnaire (PPQ) and typical clinical parameters. We calculated correlations and multivariate regression models. Of 74 patients who were assessed, 38% of those showed a low level of resilience. Our results revealed significant correlations of resilience with distress (p < 0.001, −0.49), MOCA (p = 0.003, 0.342), ECOG (p < 0.001, −0.602), stigmatization (p < 0.001, −0.558), pain (p < 0.001, −0.524), and occupation (p = 0.007, 0.329). In multivariate analyses, resilience was negatively associated with elevated ECOG (p = 0.020, β = −0.383) and stigmatization levels (p = 0.008, β = −0.350). Occupation showed a tendency towards a significant association with resilience (p = 0.088, β = −0.254). Overall, low resilience affected more than one third of our cohort. Low functional status is a specific risk factor for low resilience. The relevant influence of stigmatization on resilience is a novel finding for patients suffering from a glioma and should be routinely identified and targeted in clinical routine.
