Reimers, Carl D.

[["dc.bibliographiccitation.firstpage","383"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Neurology"],["dc.bibliographiccitation.lastpage","388"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Schneider, C."],["dc.contributor.author","Ziegler, Andreas"],["dc.contributor.author","Ricker, K."],["dc.contributor.author","Grimm, T."],["dc.contributor.author","Kress, W."],["dc.contributor.author","Reimers, Carl Detlev"],["dc.contributor.author","Meinck, H. M."],["dc.contributor.author","Reiners, Kerstin"],["dc.contributor.author","Toyka, Klaus V."],["dc.date.accessioned","2018-11-07T10:33:52Z"],["dc.date.available","2018-11-07T10:33:52Z"],["dc.date.issued","2000"],["dc.description.abstract","Objective: To investigate anticipation in proximal myotonic myopathy (PROMM). Background: PROMM is a recently described autosomal dominantly inherited disorder similar to but distinct from myotonic dystrophy (DM). DM belongs to the group of inherited disorders with anticipation caused by an unstable trinucleotide repeat expansion. In PROMM, no mutation has been identified, although PROMM has recently been mapped to a gene locus on chromosome 3q. Methods: We investigated 10 German families with the PROMM phenotype and linkage to chromosome 3q. We based our analysis of anticipation on the age of disease onset. Anticipation was assumed if the offspring had first symptoms earlier in life than his or her affected parent. For statistical analysis Independence Estimating Equations (IEE) and a Monte-Carlo bootstrap were used. Results: In 27 affected living parent-offspring pairs from these 10 families, the mean difference of disease onset was 18.8 years with either statistical analysis (p < 10(-14) and p < 10(-15)). The mean disease onset interval in years was greater in father-offspring as compared to the mother-offspring pairs (p < 0.05; IEE). Conclusion: Our findings suggest the occurrence of anticipation in parent-offspring pairs from families with the PROMM phenotype and linkage to chromosome 3q. The different disease onset intervals in mother-offspring and father-offspring pairs could indicate a mild parent-of-origin effect. These observations are compatible with the suggestion that PROMM, like DM, may be a trinucleotide repeat associated disorder. In contrast to DM, anticipation in PROMM is milder, a congenital form does not seem to occur, and fertility does not appear to be affected."],["dc.identifier.isi","000088631500012"],["dc.identifier.pmid","10932272"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44718"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0028-3878"],["dc.title","Proximal myotonic myopathy - Evidence for anticipation in families with linkage to chromosome 3q"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","166"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Clinical and Experimental Medicine"],["dc.bibliographiccitation.lastpage","170"],["dc.bibliographiccitation.volume","2"],["dc.contributor.author","Lewczuk, P."],["dc.contributor.author","Kele, H."],["dc.contributor.author","Ehrenreich, H."],["dc.contributor.author","Söhnchen, N."],["dc.contributor.author","Reimers, C. D."],["dc.date.accessioned","2021-06-01T10:49:17Z"],["dc.date.available","2021-06-01T10:49:17Z"],["dc.date.issued","2003"],["dc.description.abstract","Endothelin-1 plays an important role as a paracrine factor in the regulation of regional blood flow. Plasma levels may represent the net result of spill-over from local stimulation/release and elimination of endothelin-1. In order to compare changes in the concentration of endothelin-1 in the plasma of subjects performing different types of sports exercises we measured immunoreactive endothelin-1 in healthy volunteers ( n=20) performing in random order jogging on a treadmill and cycling on a bicycle ergometer, for 30 min each. Plasma immunoreactive endothelin-1 increased significantly after jogging (2.13+/-0.8 pg/ml versus 2.6+/-0.8 pg/ml, before and after exercise, respectively, P<0.03), whereas it decreased after cycling (2.45+/-0.76 pg/ml versus 2.25+/-0.9 pg/ml, before and after exercise, respectively, P<0.03). We suggest that microtraumatizing effects on the endothelial lining are more pronounced during jogging than during cycling, resulting in a greater increase in plasma endothelin-1, which is too high to be immediately eliminated by the lung despite exercise-induced enhanced pulmonary perfusion. In contrast, similarly enhanced lung perfusion together with a relatively lower stimulation of endothelin-1 compared with jogging, may explain the net decrease in plasma after cycling."],["dc.identifier.doi","10.1007/s102380300001"],["dc.identifier.gro","3150435"],["dc.identifier.pmid","12624706"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/86234"],["dc.language.iso","en"],["dc.notes.intern","DOI-Import GROB-425"],["dc.notes.status","final"],["dc.relation.eissn","1591-9528"],["dc.relation.issn","1591-8890"],["dc.title","Endothelin-1 concentration in plasma is increased after jogging but decreased after cycling in healthy men"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","312"],["dc.bibliographiccitation.issue","4"],["dc.bibliographiccitation.journal","Cerebrovascular Diseases"],["dc.bibliographiccitation.lastpage","317"],["dc.bibliographiccitation.volume","18"],["dc.contributor.author","Doberenz, C."],["dc.contributor.author","Paulus, Walter J."],["dc.contributor.author","Reimers, Carl Detlev"],["dc.contributor.author","Eicke, B. M."],["dc.date.accessioned","2018-11-07T10:52:13Z"],["dc.date.available","2018-11-07T10:52:13Z"],["dc.date.issued","2004"],["dc.description.abstract","This study was performed to quantify the volumetric impact of extracranial arteriosclerotic lesions. We investigated patients with different degrees of carotid stenosis as defined by conventional velocity-based duplex criteria and different patterns of collateralization. We studied the volume flow rate ( color duplex M-mode device) in 37 patients with symmetrical internal carotid artery ( ICA) plaques (<50% stenosis) and compared these data to 43 patients with a unilateral 50 - 74% stenosis, 75 - 99% stenosis (n = 73) and occlusion of the ICA ( n = 37). A 75 - 99% stenosis caused an ipsilateral flow reduction of 36% with a wide interindividual variability, and an occlusion of 51%. Collateralization via the ophthalmic artery only caused a nonsignificant ipsilateral volume flow increase, whereas the contralateral volume flow was significantly higher in patients with a patent anterior communicating artery. The increase was more pronounced in patients with an occluded vessel. Our data demonstrate a wide diversity of the hemodynamic impact of carotid stenosis as defined by 'classical' Doppler criteria. Collateral flow reflects a dynamic quantitative process. Copyright (C) 2004 S. Karger AG, Basel."],["dc.identifier.doi","10.1159/000080698"],["dc.identifier.isi","000226010900007"],["dc.identifier.pmid","15347913"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/49067"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Karger"],["dc.relation.issn","1015-9770"],["dc.title","Volume flow rate evaluation in patients with obstructive arteriosclerotic disease"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","389"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Neurology"],["dc.bibliographiccitation.lastpage","391"],["dc.bibliographiccitation.volume","61"],["dc.contributor.author","Kele, H."],["dc.contributor.author","Verheggen, Raphaela"],["dc.contributor.author","Bittermann, H. J."],["dc.contributor.author","Reimers, Carl Detlev"],["dc.date.accessioned","2018-11-07T10:36:59Z"],["dc.date.available","2018-11-07T10:36:59Z"],["dc.date.issued","2003"],["dc.description.abstract","The authors compared ultrasonography with electrophysiology for the diagnosis of carpal tunnel syndrome (CTS) on 110 clinically affected wrists. An increased cross sectional area in the proximal carpal tunnel larger than 0.11 cm(2) in combination with compression signs on longitudinal scans proved to be highly predictive for CTS (sensitivity, 89.1%; specificity, 98.0%). Ultrasound was comparable to electrophysiology in the diagnosis of CTS, and in 35% of cases changes in morphology suggested a specific therapeutic strategy."],["dc.identifier.isi","000184712600023"],["dc.identifier.pmid","12913205"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/45455"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","0028-3878"],["dc.title","The potential value of ultrasonography in the evaluation of carpal tunnel syndrome"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1000"],["dc.bibliographiccitation.issue","5"],["dc.bibliographiccitation.journal","Movement Disorders"],["dc.bibliographiccitation.lastpage","1005"],["dc.bibliographiccitation.volume","15"],["dc.contributor.author","Ziemann, Ulf"],["dc.contributor.author","Koc, J."],["dc.contributor.author","Reimers, Carl Detlev"],["dc.contributor.author","Finkenstaedt, M."],["dc.contributor.author","Paulus, Walter J."],["dc.date.accessioned","2018-11-07T10:32:08Z"],["dc.date.available","2018-11-07T10:32:08Z"],["dc.date.issued","2000"],["dc.description.abstract","Hemiballism-hemichorea in older patients with cortex contralateral to hemiballism-hemichorea is increased. hyperglycemia, associated with high signal intensity in the contralateral striatum on T1-weighted magnetic resonance scans, is now an accepted clinical entity. We present an additional patient with this disorder. Using transcranial magnetic stimulation, we show that intracortical inhibition in the motor cortex contralateral to hemiballism-hemichorea is increased. This finding is discussed in the context of current models of basal ganglia-thalamo-cortical connectivity."],["dc.identifier.doi","10.1002/1531-8257(200009)15:5<1000::AID-MDS1037>3.0.CO;2-E"],["dc.identifier.isi","000089324200036"],["dc.identifier.pmid","11009213"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44272"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Lippincott Williams & Wilkins"],["dc.relation.issn","0885-3185"],["dc.title","Exploration of motor cortex excitability in a diabetic patient with hemiballism-hemichorea"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","380"],["dc.bibliographiccitation.issue","8"],["dc.bibliographiccitation.journal","AKTUELLE NEUROLOGIE"],["dc.bibliographiccitation.lastpage","383"],["dc.bibliographiccitation.volume","27"],["dc.contributor.author","Reimers, Carl Detlev"],["dc.date.accessioned","2018-11-07T09:15:13Z"],["dc.date.available","2018-11-07T09:15:13Z"],["dc.date.issued","2000"],["dc.description.abstract","Fibromyalgia is characterised by widespread musculoskeletal pain, numerous so-called tender points, and nonspecific symptoms such as non-refreshing sleep, fatigue or abdominal complaints. Several studies proved that main motor abilities such as strength, endurance, and flexibility were reduced compared to healthy controls. Physical exercise is experienced as being abnormally strenuous. Intensive physical activity regularly exacerbates pain. Nevertheless, several studies demonstrated that regular aerobic fitness training (e.g., 30 to 45 minutes walking, jogging, or bicycling trice a week) was effective with regard to several symptoms (myalgia, pain threshold, number of tender points). Additionally, the prognosis of fibromyalgia improves. Possible triggering of pain due to intensive exercise requires a cautious increase of the workload. Longterm effects are often endangered by low compliance of many patients. This review summarises the physical restrictions as well as prophylactic and therapeutic effects of physical exercise in fibromyalgia."],["dc.identifier.doi","10.1055/s-2007-1017566"],["dc.identifier.isi","000089979800004"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27626"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Georg Thieme Verlag"],["dc.relation.issn","0302-4350"],["dc.title","Fibromyalgia and sports"],["dc.type","review"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","471"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","Journal of Neurosurgery"],["dc.bibliographiccitation.lastpage","473"],["dc.bibliographiccitation.volume","97"],["dc.contributor.author","Kele, H."],["dc.contributor.author","Verheggen, Raphaela"],["dc.contributor.author","Reimers, Carl Detlev"],["dc.date.accessioned","2018-11-07T10:16:25Z"],["dc.date.available","2018-11-07T10:16:25Z"],["dc.date.issued","2002"],["dc.description.abstract","The rare case of a patient with carpal tunnel syndrome caused by thrombosis of a persistent median artery is presented. Progressive pain in the wrist and dysesthesias in the third and fourth fingers were the atypical complaints. High-resolution ultrasonography revealed a bifid median nerve that was compressed by an occluded median artery. The intraoperative findings are described, and emphasis is placed on the importance of using high-resolution ultrasonography for presurgical diagnosis."],["dc.identifier.doi","10.3171/jns.2002.97.2.0471"],["dc.identifier.isi","000177352700032"],["dc.identifier.pmid","12186479"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/41037"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Assoc Neurological Surgeons"],["dc.relation.issn","0022-3085"],["dc.title","Carpal tunnel syndrome caused by thrombosis of the median artery: the importance of high-resolution ultrasonography for diagnosis - Case report"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","9311"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","Journal of Dairy Science"],["dc.bibliographiccitation.lastpage","9323"],["dc.bibliographiccitation.volume","100"],["dc.contributor.author","Ha, N.-T."],["dc.contributor.author","Drögemüller, C."],["dc.contributor.author","Reimer, C."],["dc.contributor.author","Schmitz-Hsu, F."],["dc.contributor.author","Bruckmaier, R.M."],["dc.contributor.author","Simianer, H."],["dc.contributor.author","Gross, J.J."],["dc.date.accessioned","2020-12-10T18:44:01Z"],["dc.date.available","2020-12-10T18:44:01Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.3168/jds.2016-12454"],["dc.identifier.issn","0022-0302"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/78298"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Liver transcriptome analysis reveals important factors involved in the metabolic adaptation of the transition cow"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1371"],["dc.bibliographiccitation.issue","45"],["dc.bibliographiccitation.journal","DMW - Deutsche Medizinische Wochenschrift"],["dc.bibliographiccitation.lastpage","1374"],["dc.bibliographiccitation.volume","125"],["dc.contributor.author","Reimers, Carl Detlev"],["dc.contributor.author","Kele, H."],["dc.contributor.author","Bittermann, H. J."],["dc.date.accessioned","2018-11-07T10:58:10Z"],["dc.date.available","2018-11-07T10:58:10Z"],["dc.date.issued","2000"],["dc.identifier.doi","10.1055/s-2000-8168"],["dc.identifier.isi","000165254500006"],["dc.identifier.pmid","11109426"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/50417"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Georg Thieme Verlag Kg"],["dc.relation.issn","0012-0472"],["dc.title","The role of imaging in neuromuscular disease"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","810"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","Journal of Neurology"],["dc.bibliographiccitation.lastpage","812"],["dc.bibliographiccitation.volume","254"],["dc.contributor.author","Arlt, Soenke"],["dc.contributor.author","Cepek, Lukas"],["dc.contributor.author","Rustenbeck, Hans Heino"],["dc.contributor.author","Prange, Hilmar"],["dc.contributor.author","Reimers, Carl Detlev"],["dc.date.accessioned","2018-11-07T11:01:59Z"],["dc.date.available","2018-11-07T11:01:59Z"],["dc.date.issued","2007"],["dc.identifier.doi","10.1007/s00415-006-0439-x"],["dc.identifier.isi","000247654300019"],["dc.identifier.pmid","17401744"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/51272"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Dr Dietrich Steinkopff Verlag"],["dc.relation.issn","0340-5354"],["dc.title","Gadolinium encephalopathy due to accidental intrathecal administration of gadopentetate dimeglumine"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dc.type.subtype","letter_note"],["dspace.entity.type","Publication"]]