Faust, Michael

[["dc.bibliographiccitation.firstpage","315"],["dc.bibliographiccitation.journal","World Neurosurgery"],["dc.bibliographiccitation.lastpage","318"],["dc.bibliographiccitation.volume","110"],["dc.contributor.author","Grau, Stefan"],["dc.contributor.author","Kellermann, Stephanie"],["dc.contributor.author","Faust, Michael"],["dc.contributor.author","Perrech, Moritz"],["dc.contributor.author","Beutner, Dirk"],["dc.contributor.author","Drzezga, Alexander"],["dc.contributor.author","Zöller, Joachim"],["dc.date.accessioned","2020-12-10T15:21:41Z"],["dc.date.available","2020-12-10T15:21:41Z"],["dc.date.issued","2018"],["dc.identifier.doi","10.1016/j.wneu.2017.11.083"],["dc.identifier.issn","1878-8750"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/73121"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-354"],["dc.title","Repair of Cerebrospinal Fluid Leakage Using a Transfrontal, Radial Adipofascial Flap: An Individual Approach Supported by Three-Dimensional Printing for Surgical Planning"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","544"],["dc.bibliographiccitation.journal","Environment international"],["dc.bibliographiccitation.lastpage","562"],["dc.bibliographiccitation.volume","120"],["dc.contributor.author","Bopp, Stephanie K."],["dc.contributor.author","Barouki, Robert"],["dc.contributor.author","Brack, Werner"],["dc.contributor.author","Dalla Costa, Silvia"],["dc.contributor.author","Dorne, Jean-Lou C. M."],["dc.contributor.author","Drakvik, Paula E."],["dc.contributor.author","Faust, Michael"],["dc.contributor.author","Karjalainen, Tuomo K."],["dc.contributor.author","Kephalopoulos, Stylianos"],["dc.contributor.author","van Klaveren, Jacob"],["dc.contributor.author","Kolossa-Gehring, Marike"],["dc.contributor.author","Kortenkamp, Andreas"],["dc.contributor.author","Lebret, Erik"],["dc.contributor.author","Lettieri, Teresa"],["dc.contributor.author","Nørager, Sofie"],["dc.contributor.author","Rüegg, Joëlle"],["dc.contributor.author","Tarazona, Jose V."],["dc.contributor.author","Trier, Xenia"],["dc.contributor.author","van de Water, Bob"],["dc.contributor.author","van Gils, Jos"],["dc.contributor.author","Bergman, Åke"],["dc.date.accessioned","2019-07-29T08:08:22Z"],["dc.date.available","2019-07-29T08:08:22Z"],["dc.date.issued","2018"],["dc.description.abstract","Humans and wildlife are exposed to an intractably large number of different combinations of chemicals via food, water, air, consumer products, and other media and sources. This raises concerns about their impact on public and environmental health. The risk assessment of chemicals for regulatory purposes mainly relies on the assessment of individual chemicals. If exposure to multiple chemicals is considered in a legislative framework, it is usually limited to chemicals falling within this framework and co-exposure to chemicals that are covered by a different regulatory framework is often neglected. Methodologies and guidance for assessing risks from combined exposure to multiple chemicals have been developed for different regulatory sectors, however, a harmonised, consistent approach for performing mixture risk assessments and management across different regulatory sectors is lacking. At the time of this publication, several EU research projects are running, funded by the current European Research and Innovation Programme Horizon 2020 or the Seventh Framework Programme. They aim at addressing knowledge gaps and developing methodologies to better assess chemical mixtures, by generating and making available internal and external exposure data, developing models for exposure assessment, developing tools for in silico and in vitro effect assessment to be applied in a tiered framework and for grouping of chemicals, as well as developing joint epidemiological-toxicological approaches for mixture risk assessment and for prioritising mixtures of concern. The projects EDC-MixRisk, EuroMix, EUToxRisk, HBM4EU and SOLUTIONS have started an exchange between the consortia, European Commission Services and EU Agencies, in order to identify where new methodologies have become available and where remaining gaps need to be further addressed. This paper maps how the different projects contribute to the data needs and assessment methodologies and identifies remaining challenges to be further addressed for the assessment of chemical mixtures."],["dc.identifier.doi","10.1016/j.envint.2018.07.037"],["dc.identifier.pmid","30170309"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62112"],["dc.language.iso","en"],["dc.relation.eissn","1873-6750"],["dc.relation.issn","0160-4120"],["dc.title","Current EU research activities on combined exposure to multiple chemicals"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","10"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Environmental Sciences Europe"],["dc.bibliographiccitation.volume","31"],["dc.contributor.author","Brack, Werner"],["dc.contributor.author","Aissa, Selim Ait"],["dc.contributor.author","Backhaus, Thomas"],["dc.contributor.author","Dulio, Valeria"],["dc.contributor.author","Escher, Beate I."],["dc.contributor.author","Faust, Michael"],["dc.contributor.author","Hilscherova, Klara"],["dc.contributor.author","Hollender, Juliane"],["dc.contributor.author","Hollert, Henner"],["dc.contributor.author","Müller, Christin"],["dc.contributor.author","Munthe, John"],["dc.contributor.author","Posthuma, Leo"],["dc.contributor.author","Seiler, Thomas-Benjamin"],["dc.contributor.author","Slobodnik, Jaroslav"],["dc.contributor.author","Teodorovic, Ivana"],["dc.contributor.author","Tindall, Andrew J."],["dc.contributor.author","de Aragão Umbuzeiro, Gisela"],["dc.contributor.author","Zhang, Xiaowei"],["dc.contributor.author","Altenburger, Rolf"],["dc.date.accessioned","2019-07-29T07:38:55Z"],["dc.date.available","2019-07-29T07:38:55Z"],["dc.date.issued","2019"],["dc.description.abstract","The present monitoring and assessment of the chemical status of water bodies fail to characterize the likelihood that complex mixtures of chemicals affect water quality. The European Collaborative Project SOLUTIONS suggests that this likelihood can be estimated with effect-based methods (EBMs) complemented by chemical screening and/or impact modeling. These methods should be used to identify the causes of impacted water quality and to develop programs of measures to improve water quality. Along this line of reasoning, effect-based methods are recommended for Water Framework Directive (WFD) monitoring to cover the major modes of action in the universe of environmentally relevant chemicals so as to evaluate improvements of water quality upon implementing the measures. To this end, a minimum battery of bioassays has been recommended including short-term toxicity to algae, Daphnia and fish embryos complemented with in vitro and short-term in vivo tests on mode-of-action specific effects as proxies for long-term toxicity. The likelihood of adverse impacts can be established with effect-based trigger values, which differentiate good from poor water quality in close alignment with Environmental Quality Standards for individual chemicals, while taking into account mixture toxicity. The use of EBMs is suggested in the WFD as one avenue to establish the likelihood of adverse effects due to chemical pollution in European water systems. The present paper has been written as one component of a series of policy briefs to support decisions on water quality monitoring and management under the WFD."],["dc.identifier.doi","10.1186/s12302-019-0192-2"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62111"],["dc.language.iso","en"],["dc.relation.issn","2190-4707"],["dc.relation.issn","2190-4715"],["dc.title","Effect-based methods are key. The European Collaborative Project SOLUTIONS recommends integrating effect-based methods for diagnosis and monitoring of water quality"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","167"],["dc.bibliographiccitation.issue","S1"],["dc.bibliographiccitation.journal","Kölner Zeitschrift für Soziologie und Sozialpsychologie"],["dc.bibliographiccitation.lastpage","194"],["dc.bibliographiccitation.volume","70"],["dc.contributor.author","Faust, Michael"],["dc.contributor.author","Kädtler, Jürgen"],["dc.date.accessioned","2019-07-29T08:09:30Z"],["dc.date.available","2019-07-29T08:09:30Z"],["dc.date.issued","2018"],["dc.description.abstract","Die Finanzialisierung des Unternehmens wird seit den 1990er Jahren auch in Deutschland als ein bedeutsamer und an Bedeutung gewinnender Aspekt der kapitalistischen Entwicklung dingfest gemacht. Seit einiger Zeit wird allerdings verbreitet eine konzeptionelle Überdehnung des Begriffs der Finanzialisierung beklagt. Dieser wird zu unterschiedlich und oft mehrdeutig definiert und nicht klar genug von verwandt erscheinenden Begriffen abgegrenzt. Finanzialisierung wird vorschnell mit fixen Effekten verbunden, die zudem zu Stufenmodellen kapitalistischer Entwicklung verdichtet werden. Bei der Analyse der Wirkungen wird isoliert auf Finanzialsierungseffekte abgestellt, ohne Interaktionseffekte mit anderen Strukturierungen von Feldern und damit die Multirefentialität von Unternehmen zu berücksichtigen. Der Behebung dieser Mängel dient ein Vorschlag zur Analyse der Finanzialisierung des Unternehmens, der sich auf allgemeinere soziologische Konzepte der Strukturierung und Dynamik wirtschaftlicher Felder und des darin operierenden „multireferentiellen Unternehmens“ stützt. Auf dieser Grundlage werden Episoden der Finanzialisierung in Deutschland analysiert, an denen deren Dynamik und Grenzen deutlich werden. Die Finanzialisierung von Unternehmen in Deutschland ist demnach strukturell begrenzt, institutionell umkämpft und entfaltet ihre Wirkungen in unterschiedlichen Akteurskonstellationen auf der Unternehmensebene, die ihre je spezifischen Ausprägungen auch deswegen haben, weil Unternehmen multipel und unterschiedlich eingebettet sind."],["dc.identifier.doi","10.1007/s11577-018-0543-9"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62113"],["dc.language.iso","de"],["dc.relation.issn","0023-2653"],["dc.relation.issn","1861-891X"],["dc.title","Die Finanzialisierung von Unternehmen"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","224"],["dc.bibliographiccitation.issue","6399"],["dc.bibliographiccitation.journal","Science (New York, N.Y.)"],["dc.bibliographiccitation.lastpage","226"],["dc.bibliographiccitation.volume","361"],["dc.contributor.author","Kortenkamp, Andreas"],["dc.contributor.author","Faust, Michael"],["dc.date.accessioned","2019-07-29T08:17:14Z"],["dc.date.available","2019-07-29T08:17:14Z"],["dc.date.issued","2018"],["dc.description.abstract","Humans and wildlife are continuously exposed to multiple chemicals from different sources and via different routes, both simultaneously and in sequence. Scientific evidence for heightened toxicity from such mixtures is mounting, yet regulation is lagging behind. Ensuring appropriate regulation of chemical mixture risks will require stronger legal stimuli as well as close integration of different parts of the regulatory systems in order to meet the data and testing requirements for mixture risk assessment. Until about a decade ago, toxicologists, risk assessors, and regulators regarded risks from chemical mixtures as negligible, as long as exposures to all single chemicals in the cocktail were below the levels judged to be safe for each chemical alone (1, 2). However, an increasing body of scientific evidence has challenged this notion, showing that a neglect of mixture effects can cause chemical risks to be underestimated (see the figure). International bodies such as the World Health Organization now acknowledge the need for considering mixtures in chemical risk assessment and regulation (3). This would align toxicological risk assessment with the clinical sciences and their long tradition of investigating drug-drug interactions. Yet, with few exceptions, regulatory systems around the world still focus overwhelmingly on single-chemical assessments, and the translation of scientific evidence about mixture effects into better regulation is extremely slow."],["dc.identifier.doi","10.1126/science.aat9219"],["dc.identifier.pmid","30026211"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/62114"],["dc.language.iso","en"],["dc.relation.eissn","1095-9203"],["dc.relation.issn","0036-8075"],["dc.relation.issn","1095-9203"],["dc.title","Regulate to reduce chemical mixture risk"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]