Rieken, Stefan

[["dc.bibliographiccitation.firstpage","383"],["dc.bibliographiccitation.issue","3"],["dc.bibliographiccitation.journal","Cancers"],["dc.bibliographiccitation.volume","11"],["dc.contributor.author","Held, Thomas"],["dc.contributor.author","Akbaba, Sati"],["dc.contributor.author","Lang, Kristin"],["dc.contributor.author","Harrabi, Semi"],["dc.contributor.author","Bernhardt, Denise"],["dc.contributor.author","Freudlsperger, Christian"],["dc.contributor.author","Kargus, Steffen"],["dc.contributor.author","Plinkert, Peter"],["dc.contributor.author","Rieken, Stefan"],["dc.contributor.author","Herfarth, Klaus"],["dc.contributor.author","Debus, Jürgen"],["dc.contributor.author","Adeberg, Sebastian"],["dc.date.accessioned","2020-07-16T10:33:52Z"],["dc.date.available","2020-07-16T10:33:52Z"],["dc.date.issued","2019-03-19"],["dc.description.abstract","Purpose: The aim of the current evaluation was to assess central nervous system necrosis (CNSN) after re-irradiation with carbon ions (CR) in two-hundred seventeen (n = 217) patients with recurrent head-and-neck cancer (HNC). Methods: Thirty-six (n = 36) patients with CNSN were assessed retrospectively regarding clinical symptoms and radiographic response. Results: CNSN were classified according to clinical management in line with the Common Terminology Criteria for Adverse Events (CTCAE) v5.0. At a median follow-up of 25.3 months (range 3.3⁻79.9 months), the median time interval until occurrence of grade I, II, and III CNSN was 9.2 months (range 2.8⁻75.0 months), 10.2 months (range 2.3⁻60.5 months), and 16.6 months (range 8.7⁻32.5 months), respectively. In one patient with an adenocarcinoma infiltrating the frontal lobe, an extensive CNSN grade IV was suspected but the patient declined surgical intervention. Radiographic response after treatment of CNSN grade I, II, and III, defined as ≥25% reduction of the T2 alteration on Magnetic Resonance Imaging (MRI), was observed in 4 (16.0%), 5 (29.4%), and 4 (80%) patients, respectively. Conclusion: CNSN occurred late and frequent after re-irradiation with carbon ions in patients with HNC infiltrating the base of skull. The clinical outcome with adequate treatment was encouraging but correct diagnosis of CNSN remains challenging."],["dc.identifier.doi","10.3390/cancers11030383"],["dc.identifier.pmid","30893824"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/67183"],["dc.language.iso","en"],["dc.relation.issn","2072-6694"],["dc.title","Clinical Management of Blood⁻Brain Barrier Disruptions after Active Raster-Scanned Carbon Ion Re-Radiotherapy in Patients with Recurrent Head-and-Neck Cancer"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Bernhardt, Denise"],["dc.contributor.author","Bozorgmehr, Farastuk"],["dc.contributor.author","Adeberg, Sebastian"],["dc.contributor.author","König, Laila"],["dc.contributor.author","Kappes, Jutta"],["dc.contributor.author","Thomas, Michael"],["dc.contributor.author","Herth, Felix"],["dc.contributor.author","Heußel, Claus"],["dc.contributor.author","Debus, Jürgen"],["dc.contributor.author","Steins, Martin"],["dc.contributor.author","Rieken, Stefan"],["dc.date.accessioned","2020-07-10T07:20:41Z"],["dc.date.available","2020-07-10T07:20:41Z"],["dc.date.issued","2017"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66973"],["dc.title","P17-2-jD Outcome and prognostic factors in patients with brain metastases from small-cell lung cancer treated with whole brain radiotherapy"],["dc.type","report"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","130"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Radiation oncology"],["dc.bibliographiccitation.volume","7"],["dc.contributor.author","Hauswald, Henrik"],["dc.contributor.author","Dittmar, Jan-Oliver"],["dc.contributor.author","Habermehl, Daniel"],["dc.contributor.author","Rieken, Stefan"],["dc.contributor.author","Sterzing, Florian"],["dc.contributor.author","Debus, Jürgen"],["dc.contributor.author","Combs, Stephanie E"],["dc.date.accessioned","2020-07-16T09:12:49Z"],["dc.date.available","2020-07-16T09:12:49Z"],["dc.date.issued","2012-08-02"],["dc.description.abstract","To retrospectively access outcome and toxicity of whole brain radiotherapy (WBRT) in patients with multiple brain metastases (BM) from malignant melanoma (MM)."],["dc.identifier.doi","10.1186/1748-717X-7-130"],["dc.identifier.pmid","22857154"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/67114"],["dc.language.iso","en"],["dc.relation.issn","1748-717X"],["dc.title","Efficacy and toxicity of whole brain radiotherapy in patients with multiple cerebral metastases from malignant melanoma"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","394"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","International Journal of Radiation Oncology, Biology, Physics"],["dc.bibliographiccitation.lastpage","399"],["dc.bibliographiccitation.volume","83"],["dc.contributor.author","Rieken, Stefan"],["dc.contributor.author","Habermehl, Daniel"],["dc.contributor.author","Wuerth, Lena"],["dc.contributor.author","Brons, Stephan"],["dc.contributor.author","Mohr, Angela"],["dc.contributor.author","Lindel, Katja"],["dc.contributor.author","Weber, Klaus"],["dc.contributor.author","Haberer, Thomas"],["dc.contributor.author","Debus, Jürgen"],["dc.contributor.author","Combs, Stephanie E"],["dc.date.accessioned","2020-07-10T08:22:35Z"],["dc.date.available","2020-07-10T08:22:35Z"],["dc.date.issued","2012-05-01"],["dc.description.abstract","To investigate the effect of carbon ion irradiation on glioma cell migration."],["dc.identifier.doi","10.1016/j.ijrobp.2011.06.2004"],["dc.identifier.pmid","22056068"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/67012"],["dc.language.iso","en"],["dc.relation.eissn","1879-355X"],["dc.relation.issn","0360-3016"],["dc.title","Carbon ion irradiation inhibits glioma cell migration through downregulation of integrin expression"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","S1045"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Journal of Thoracic Oncology"],["dc.bibliographiccitation.lastpage","S1046"],["dc.bibliographiccitation.volume","12"],["dc.contributor.author","Bernhardt, Denise"],["dc.contributor.author","Adeberg, Sebastian"],["dc.contributor.author","Bozorgmehr, Farastuk"],["dc.contributor.author","Hoerner-Rieber, Juliane"],["dc.contributor.author","Kappes, Jutta"],["dc.contributor.author","Thomas, Michael"],["dc.contributor.author","Bischoff, Helge"],["dc.contributor.author","Herth, Felix Jf"],["dc.contributor.author","Heussel, Claus"],["dc.contributor.author","Debus, Jürgen"],["dc.contributor.author","Steins, Martin"],["dc.contributor.author","Rieken, Stefan"],["dc.date.accessioned","2020-07-10T08:22:55Z"],["dc.date.available","2020-07-10T08:22:55Z"],["dc.date.issued","2017"],["dc.identifier.doi","10.1016/j.jtho.2016.11.1460"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/67016"],["dc.relation.issn","1556-0864"],["dc.title","P2.05-025 9-Year Experience: Prophylactic Cranial Irradiation in Extensive Disease Small-Cell Lung Cancer"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.contributor.author","Bernhardt, Denise"],["dc.contributor.author","Adeberg, Sebastian"],["dc.contributor.author","Bozorgmehr, Farastuk"],["dc.contributor.author","Opfermann, Nils"],["dc.contributor.author","Hoerner-Rieber, Juliane"],["dc.contributor.author","Repka, Michael"],["dc.contributor.author","Kappes, Jutta"],["dc.contributor.author","Thomas, Michael"],["dc.contributor.author","Bischoff, Helge"],["dc.contributor.author","Herth, Felix"],["dc.contributor.author","Heußel, Claus"],["dc.contributor.author","Debus, Jürgen"],["dc.contributor.author","Steins, Martin"],["dc.contributor.author","Rieken, Stefan"],["dc.date.accessioned","2020-07-10T07:20:36Z"],["dc.date.available","2020-07-10T07:20:36Z"],["dc.date.issued","2016"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/66972"],["dc.title","9-year experience: Prophylactic cranial irradiation in extensive disease small-cell lung cancer"],["dc.type","report"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","18"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Radiation oncology"],["dc.bibliographiccitation.volume","8"],["dc.contributor.author","Rieken, Stefan"],["dc.contributor.author","Habermehl, Daniel"],["dc.contributor.author","Welzel, Thomas"],["dc.contributor.author","Mohr, Angela"],["dc.contributor.author","Lindel, Katja"],["dc.contributor.author","Debus, Jürgen"],["dc.contributor.author","Combs, Stephanie E"],["dc.date.accessioned","2020-07-16T09:13:28Z"],["dc.date.available","2020-07-16T09:13:28Z"],["dc.date.issued","2013-01-23"],["dc.description.abstract","Radiotherapy is controversially discussed in the management of benign disorders for fear of late sequelae such as tumor induction. This study was initiated to investigate long-term toxicity, treatment outcome and prognostic factors after radiotherapy (RT) in patients with pituitary adenomas."],["dc.identifier.doi","10.1186/1748-717X-8-18"],["dc.identifier.pmid","23343416"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/67122"],["dc.language.iso","en"],["dc.relation.issn","1748-717X"],["dc.title","Long term toxicity and prognostic factors of radiation therapy for secreting and non-secreting pituitary adenomas"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","253"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Neurosurgery"],["dc.bibliographiccitation.lastpage","260"],["dc.bibliographiccitation.volume","84"],["dc.contributor.author","El Shafie, Rami A."],["dc.contributor.author","Paul, Angela"],["dc.contributor.author","Bernhardt, Denise"],["dc.contributor.author","Lang, Kristin"],["dc.contributor.author","Welzel, Thomas"],["dc.contributor.author","Sprave, Tanja"],["dc.contributor.author","Hommertgen, Adriane"],["dc.contributor.author","Krisam, Johannes"],["dc.contributor.author","Schmitt, Daniela"],["dc.contributor.author","Klüter, Sebastian"],["dc.contributor.author","Schubert, Kai"],["dc.contributor.author","Klose, Christina"],["dc.contributor.author","Kieser, Meinhard"],["dc.contributor.author","Debus, Jürgen"],["dc.contributor.author","Rieken, Stefan"],["dc.date.accessioned","2020-07-16T09:11:12Z"],["dc.date.available","2020-07-16T09:11:12Z"],["dc.date.issued","2019"],["dc.description.abstract","Stereotactic radiosurgery (SRS) of brain metastases (BM) is recommended in oligometastatic scenarios as a less toxic treatment alternative to whole-brain radiotherapy. Recent findings support SRS for patients with multiple (>3) BM. Furthermore, advances in MR imaging have facilitated the detection of very small BM, as advances in SRS technology have facilitated the highly conformal and simultaneous treatment of multiple target lesions."],["dc.identifier.doi","10.1093/neuros/nyy026"],["dc.identifier.pmid","29554321"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/67096"],["dc.language.iso","en"],["dc.relation.eissn","1524-4040"],["dc.relation.issn","0148-396X"],["dc.title","Robotic Radiosurgery for Brain Metastases Diagnosed With Either SPACE or MPRAGE Sequence (CYBER-SPACE)-A Single-Center Prospective Randomized Trial"],["dc.type","journal_article"],["dc.type.internalPublication","unknown"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","132"],["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Radiation oncology"],["dc.bibliographiccitation.volume","6"],["dc.contributor.author","Rieken, Stefan"],["dc.contributor.author","Habermehl, Daniel"],["dc.contributor.author","Mohr, Angela"],["dc.contributor.author","Wuerth, Lena"],["dc.contributor.author","Lindel, Katja"],["dc.contributor.author","Weber, Klaus"],["dc.contributor.author","Debus, Jürgen"],["dc.contributor.author","Combs, Stephanie E"],["dc.date.accessioned","2020-07-16T09:12:44Z"],["dc.date.available","2020-07-16T09:12:44Z"],["dc.date.issued","2011-10-06"],["dc.description.abstract","Sublethal photon irradiation was recently suspected to increase tumor cell motility and promote locoregional recurrence of disease. This study was set up to describe mechanisms underlying increased glioma cell migration through photon irradiation and to analyse the modifiability of photon-altered glioma cell motility by integrin inhibition."],["dc.identifier.doi","10.1186/1748-717X-6-132"],["dc.identifier.pmid","21978494"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/67113"],["dc.language.iso","en"],["dc.relation.issn","1748-717X"],["dc.title","Targeting ανβ3 and ανβ5 inhibits photon-induced hypermigration of malignant glioma cells"],["dc.type","journal_article"],["dc.type.internalPublication","no"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.issue","1"],["dc.bibliographiccitation.journal","Scientific Reports"],["dc.bibliographiccitation.volume","10"],["dc.contributor.author","Hartmann, Laura"],["dc.contributor.author","Schröter, Philipp"],["dc.contributor.author","Osen, Wolfram"],["dc.contributor.author","Baumann, Daniel"],["dc.contributor.author","Offringa, Rienk"],["dc.contributor.author","Moustafa, Mahmoud"],["dc.contributor.author","Will, Rainer"],["dc.contributor.author","Debus, Jürgen"],["dc.contributor.author","Brons, Stephan"],["dc.contributor.author","Rieken, Stefan"],["dc.contributor.author","Eichmüller, Stefan B."],["dc.date.accessioned","2021-04-14T08:26:47Z"],["dc.date.available","2021-04-14T08:26:47Z"],["dc.date.issued","2020"],["dc.identifier.doi","10.1038/s41598-020-78577-8"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/82076"],["dc.language.iso","en"],["dc.notes.intern","DOI Import GROB-399"],["dc.relation.eissn","2045-2322"],["dc.title","Photon versus carbon ion irradiation: immunomodulatory effects exerted on murine tumor cell lines"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dspace.entity.type","Publication"]]