Zeeck, Axel

[["dc.bibliographiccitation.firstpage","801"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","The Journal of Antibiotics"],["dc.bibliographiccitation.lastpage","806"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Krastel, P."],["dc.contributor.author","Zeeck, Axel"],["dc.date.accessioned","2018-11-07T10:05:54Z"],["dc.date.available","2018-11-07T10:05:54Z"],["dc.date.issued","2002"],["dc.description.abstract","A detailed screening of the secondary metabolite pattern produced by different athropod associated strains of the species Streptomyces anulatus resulted in the isolation and structure elucidation of the endophenazines Asimilar toD (2, 4similar to6). The structures were assigned by spectroscopic methods and chemical transformations. 4 represents a chromophoric system based on a phenazin-7-one, 5 and 6 are new 5, 10-dihydrophenazine derivatives."],["dc.identifier.isi","000178293400003"],["dc.identifier.pmid","12458769"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38993"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Japan Antibiot Res Assn"],["dc.relation.issn","0021-8820"],["dc.title","Endophenazines A similar to D, new phenazine antibiotics from the athropod associated endosymbiont Streptomyces anulatus II. Structure elucidation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","983"],["dc.bibliographiccitation.issue","6"],["dc.bibliographiccitation.journal","European Journal of Organic Chemistry"],["dc.bibliographiccitation.lastpage","987"],["dc.contributor.author","Dubeler, A."],["dc.contributor.author","Krastel, P."],["dc.contributor.author","Floss, Heinz G."],["dc.contributor.author","Zeeck, Axel"],["dc.date.accessioned","2018-11-07T10:31:19Z"],["dc.date.available","2018-11-07T10:31:19Z"],["dc.date.issued","2002"],["dc.description.abstract","Echinosporin (1), a known antibiotic with a unique tricyclic acetal-lactone structure, is produced by Streptomyces erythraeus (strain Tu 4015), together with the novel 7-deoxy-echinosporin (2) as minor compound, which was fully characterized. The biosynthesis of I was established by feeding experiments with C-13-labelled precursors. The results revealed that I was formed by the shikimate pathway, with chorismate as a biosynthetic intermediate. The proposed mechanism for the conversion of chorismate into I represents a new branch of the shikimate pathway, producing a nonaromatic metabolite. In addition, the influence of aromatic amino acids and of glyphosate, an inhibitor in the shikimate pathway of plants, was investigated. (C) Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002."],["dc.identifier.isi","000174531400003"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44081"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Wiley-v C H Verlag Gmbh"],["dc.relation.issn","1434-193X"],["dc.title","Biosynthesis of the antibiotic echinosporin by a novel branch of the shikimate pathway"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","147"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","FEMS Microbiology Letters"],["dc.bibliographiccitation.lastpage","151"],["dc.bibliographiccitation.volume","196"],["dc.contributor.author","Fiedler, H. P."],["dc.contributor.author","Krastel, P."],["dc.contributor.author","Mueller, J."],["dc.contributor.author","Gebhardt, Klaus"],["dc.contributor.author","Zeeck, Axel"],["dc.date.accessioned","2018-11-07T09:16:29Z"],["dc.date.available","2018-11-07T09:16:29Z"],["dc.date.issued","2001"],["dc.description.abstract","Enterobactin is described in the literature as the typical iron-chelating compound (siderophore) produced by bacteria of the family Enterobacteriaceae. In the course of a HPLC with diode array detection screening programme for detection of novel secondary metabolites, enterobactin, its biosynthetic precursor 2,3-dihydroxy-N-benzoylserine and its linear dimer and trimer condensation products were found to be produced by two Streptomyces strains besides the trihydroxamate-type siderophores desferri-ferrioxamine B and E. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved."],["dc.identifier.doi","10.1016/S0378-1097(01)00053-2"],["dc.identifier.isi","000167748300011"],["dc.identifier.pmid","11267771"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/27948"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Elsevier Science Bv"],["dc.relation.issn","0378-1097"],["dc.title","Enterobactin: the characteristic catecholate siderophore of Enterobacteriaceae is produced by Streptomyces species"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","1258"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","Journal of Natural Products"],["dc.bibliographiccitation.lastpage","1260"],["dc.bibliographiccitation.volume","63"],["dc.contributor.author","Puder, C."],["dc.contributor.author","Krastel, P."],["dc.contributor.author","Zeeck, Axel"],["dc.date.accessioned","2018-11-07T10:31:18Z"],["dc.date.available","2018-11-07T10:31:18Z"],["dc.date.issued","2000"],["dc.description.abstract","Five new piperidine alkaloids (1-5), named streptazones A, B-1, B-2, C, and D, were isolated from Streptomyces strains FORM5 and Al. Their structures were established on the basis of detailed MS and NMR analysis. Streptazone A (1) exhibited significant cytotoxic activity against selected human tumor cell lines."],["dc.identifier.doi","10.1021/np0001373"],["dc.identifier.isi","000089540100017"],["dc.identifier.pmid","11000031"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/44077"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Amer Chemical Soc"],["dc.relation.issn","0163-3864"],["dc.title","Streptazones A, B-1, B-2, C, and D: New piperidine alkaloids from streptomycetes"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.artnumber","PII S0378-1097(02)01065-0"],["dc.bibliographiccitation.firstpage","199"],["dc.bibliographiccitation.issue","2"],["dc.bibliographiccitation.journal","FEMS Microbiology Letters"],["dc.bibliographiccitation.lastpage","205"],["dc.bibliographiccitation.volume","217"],["dc.contributor.author","Gebhardt, Klaus"],["dc.contributor.author","Schimana, J."],["dc.contributor.author","Müller, J."],["dc.contributor.author","Fiedler, Hans-Peter"],["dc.contributor.author","Kallenborn, H. G."],["dc.contributor.author","Holzenkämpfer, M."],["dc.contributor.author","Krastel, P."],["dc.contributor.author","Zeeck, Axel"],["dc.contributor.author","Vater, Joachim"],["dc.contributor.author","Hotzel, A."],["dc.contributor.author","Schmid, D. G."],["dc.contributor.author","Rheinheimer, J."],["dc.contributor.author","Dettner, K."],["dc.date.accessioned","2018-11-07T09:41:43Z"],["dc.date.available","2018-11-07T09:41:43Z"],["dc.date.issued","2002"],["dc.description.abstract","Endosymbiotic bacteria from the genus Bacillus were isolated from different compartments of the gut of various members of insects (Hexapoda) and millipedes (Dipiopoda). They were grown in submerged culture and investigated by biological assays and HPLC-diode array analysis regarding their production of bioactive metabolites, which were isolated and determined in structure. Known compounds and yet unknown derivatives from the primary metabolism were detected, as well as antibacterially and antifungally acting peptide antibiotics. (C) 2002 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved."],["dc.identifier.doi","10.1016/S0378-1097(02)01065-0"],["dc.identifier.isi","000179884500010"],["dc.identifier.pmid","12480104"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/33792"],["dc.language.iso","en"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.relation.issn","0378-1097"],["dc.title","Screening for biologically active metabolites with endosymbiotic bacilli isolated from arthropods"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","635"],["dc.bibliographiccitation.issue","7"],["dc.bibliographiccitation.journal","The Journal of Antibiotics"],["dc.bibliographiccitation.lastpage","642"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Schlorke, O."],["dc.contributor.author","Krastel, P."],["dc.contributor.author","Mueller, I."],["dc.contributor.author","Uson, I."],["dc.contributor.author","Dettner, K."],["dc.contributor.author","Zeeck, Axel"],["dc.date.accessioned","2018-11-07T10:21:51Z"],["dc.date.available","2018-11-07T10:21:51Z"],["dc.date.issued","2002"],["dc.description.abstract","Cetoniacytone A (1) and some related minor. components (2, 6, 7) were produced by Actinomyces sp. (strain Lu 9419), which was isolated from the intestines of a rose chafer (Cetonia aureata). The structures of the novel metabolites were established by detailed spectroscopic analysis. The absolute configuration of 1 was determined by X-ray analysis and derivatisation with chiral acids. 1 exhibits a significant cytotoxicity against selected tumor cell lines. The biosynthesis of 1 was studied by feeding C-13 labelled precursors. The results suggest that the characteristic p-C7N skeleton of the aminocarba sugar is formed via the pentose phosphate pathway by cyclisation of a heptulose phosphate intermediate."],["dc.identifier.isi","000177108900003"],["dc.identifier.pmid","12243453"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/42173"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Japan Antibiot Res Assn"],["dc.relation.issn","0021-8820"],["dc.title","Structure and biosynthesis of cetoniacytone A, a cytotoxic aminocarba sugar produced by an endosymbiontic Actinoimyces"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","794"],["dc.bibliographiccitation.issue","9"],["dc.bibliographiccitation.journal","The Journal of Antibiotics"],["dc.bibliographiccitation.lastpage","800"],["dc.bibliographiccitation.volume","55"],["dc.contributor.author","Gebhardt, Klaus"],["dc.contributor.author","Schimana, J."],["dc.contributor.author","Krastel, P."],["dc.contributor.author","Dettner, K."],["dc.contributor.author","Rheinheimer, J."],["dc.contributor.author","Zeeck, Axel"],["dc.contributor.author","Fiedler, H. P."],["dc.date.accessioned","2018-11-07T10:05:51Z"],["dc.date.available","2018-11-07T10:05:51Z"],["dc.date.issued","2002"],["dc.description.abstract","Four new members of the phenazine family, endophenazines Asimilar toD, and the already known phenazine-1-carboxylic acid (tubermycin B) were detected in the culture broth of various endosymbiotic Streptomyces anulatus strains by chemical screening in a combination of TLC-staining reagents and HPLC-diode array analysis. The endosymbiotic strains were isolated from four different arthropod hosts at various sites. The new phenazine compounds showed antimicrobial activities against Gram-positive bacteria and some filamentous fungi, and herbicidal activity against Lemna minor (duckweed)."],["dc.identifier.isi","000178293400002"],["dc.identifier.pmid","12458768"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/38981"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Japan Antibiot Res Assn"],["dc.relation.issn","0021-8820"],["dc.title","Endophenazines A similar to D, new phenazine antibiotics from the arthropod associated endosymbiont Streptomyces anulatus I. Taxonomy, fermentation, isolation and biological activities"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]

[["dc.bibliographiccitation.firstpage","715"],["dc.bibliographiccitation.issue","11"],["dc.bibliographiccitation.journal","The Journal of Antibiotics"],["dc.bibliographiccitation.lastpage","720"],["dc.bibliographiccitation.volume","57"],["dc.contributor.author","Holtzel, A."],["dc.contributor.author","Schmid, D. G."],["dc.contributor.author","Nicholson, G. J."],["dc.contributor.author","Krastel, P."],["dc.contributor.author","Zeeck, Axel"],["dc.contributor.author","Gebhardt, Klaus"],["dc.contributor.author","Fiedler, H. P."],["dc.contributor.author","Jung, G."],["dc.date.accessioned","2018-11-07T10:44:20Z"],["dc.date.available","2018-11-07T10:44:20Z"],["dc.date.issued","2004"],["dc.description.abstract","The structures of new cytochalasan fungal metabolites aspochalamins Asimilar toD have been elucidated by ESI-FTICR-MS, NMR spectroscopy, and chiral amino acid analysis. Aspochalamins Asimilar toD consist of different aspochalasin skeletons connected at position C-19 to the N terminus of the tripeptidic moiety amide anthranoyl-L-alanine-E-didehydrotryptamide. Furthermore, the structure of a new aspochalasin analog, aspochalasin Z, was derived from its molecular mass and NMR data as 10-isopropyl-14-methyl[11]-cytochalasa-6Z, 13E, 19E-triene-1,21-dione."],["dc.identifier.isi","000225409000002"],["dc.identifier.pmid","15712665"],["dc.identifier.uri","https://resolver.sub.uni-goettingen.de/purl?gro-2/47247"],["dc.notes.status","zu prüfen"],["dc.notes.submitter","Najko"],["dc.publisher","Japan Antibiotics Research Assoc"],["dc.relation.issn","0021-8820"],["dc.title","Aspochalamins A similar to D and aspochalasin Z produced by the endosymbiotic fungus Aspergillus niveus LU 9575 II. Structure elucidation"],["dc.type","journal_article"],["dc.type.internalPublication","yes"],["dc.type.peerReviewed","yes"],["dc.type.status","published"],["dspace.entity.type","Publication"]]